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Volumn 15, Issue 6, 2016, Pages 819-826

Andrographolide inhibits prostate cancer by targeting cell cycle regulators, CXCR3 and CXCR7 chemokine receptors

Author keywords

Andrographolide; Cell cycle; chemokine; chemokine receptor and prostate cancer; CXCL11; CXCR3; CXCR7; Cyclins

Indexed keywords

ANDROGRAPHOLIDE; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR7; CXCL11 CHEMOKINE; CYCLIN A2; CYCLIN B1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN E2; CYCLINE; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CCNB1 PROTEIN, HUMAN; CCNE2 PROTEIN, HUMAN; CDK1 PROTEIN, HUMAN; CELL CYCLE PROTEIN; CHEMOKINE RECEPTOR CXCR; CXCL11 PROTEIN, HUMAN; CXCR3 PROTEIN, HUMAN; CXCR7 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; DITERPENE; HISTONE; NUCLEAR PROTEIN; PLANT EXTRACT; PROTEIN TYROSINE KINASE; WEE1 PROTEIN, HUMAN;

EID: 84962033896     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2016.1148836     Document Type: Article
Times cited : (40)

References (46)
  • 1
    • 39149137869 scopus 로고    scopus 로고
    • Plant-derived compounds in clinical trials
    • 18275914
    • A.Saklani, S.K.Kutty. Plant-derived compounds in clinical trials. Drug Discov Today 2008; 13:161-71; PMID:18275914; http://dx.doi.org/10.1016/j.drudis.2007.10.010
    • (2008) Drug Discov Today , vol.13 , pp. 161-171
    • Saklani, A.1    Kutty, S.K.2
  • 2
    • 77953713797 scopus 로고    scopus 로고
    • Bioavailability challenges associated with development of anti-cancer phenolics
    • 20370701
    • S.Gao, M.Hu. Bioavailability challenges associated with development of anti-cancer phenolics. Mini Rev Med Chem 2010; 10:550-67; PMID:20370701; http://dx.doi.org/10.2174/138955710791384081
    • (2010) Mini Rev Med Chem , vol.10 , pp. 550-567
    • Gao, S.1    Hu, M.2
  • 4
    • 84906255505 scopus 로고    scopus 로고
    • Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats
    • NOT_FOUND
    • H.W.Chen, C.S.Huang, C.C.Li, A.H.Lin, Y.J.Huang, T.S.Wang, H.T.Yao, C.K.Lii. Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats. Toxicol Appl Pharm 2014; 280:1-9; PMID:NOT_FOUND; http://dx.doi.org/10.1016/j.taap.2014.07.024
    • (2014) Toxicol Appl Pharm , vol.280 , pp. 1-9
    • Chen, H.W.1    Huang, C.S.2    Li, C.C.3    Lin, A.H.4    Huang, Y.J.5    Wang, T.S.6    Yao, H.T.7    Lii, C.K.8
  • 5
    • 0141457852 scopus 로고    scopus 로고
    • Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata
    • 14641821
    • S.Rajagopal, R.A.Kumar, D.S.Deevi, C.Satyanarayana, R.Rajagopalan. Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata. J Exp Ther Oncol 2003; 3:147-58; PMID:14641821; http://dx.doi.org/10.1046/j.1359-4117.2003.01090.x
    • (2003) J Exp Ther Oncol , vol.3 , pp. 147-158
    • Rajagopal, S.1    Kumar, R.A.2    Deevi, D.S.3    Satyanarayana, C.4    Rajagopalan, R.5
  • 6
    • 77953591188 scopus 로고    scopus 로고
    • Andrographolide sensitizes ras-transformed cells to radiation in vitro and in vivo
    • 20610044
    • S.K.Hung, L.C.Hung, C.D.Kuo, K.Y.Lee, M.S.Lee, H.Y.Lin, Y.J.Chen, S.L.Fu. Andrographolide sensitizes ras-transformed cells to radiation in vitro and in vivo. Int J Radiat Oncol Biol Phys 2010; 77:1232-9; PMID:20610044; http://dx.doi.org/10.1016/j.ijrobp.2010.01.007
    • (2010) Int J Radiat Oncol Biol Phys , vol.77 , pp. 1232-1239
    • Hung, S.K.1    Hung, L.C.2    Kuo, C.D.3    Lee, K.Y.4    Lee, M.S.5    Lin, H.Y.6    Chen, Y.J.7    Fu, S.L.8
  • 9
    • 84883176178 scopus 로고    scopus 로고
    • CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential
    • 23382783
    • O.Wald, O.M.Shapira, U.Izhar. CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential. Theranostics 2013; 3:26-33; PMID:23382783; http://dx.doi.org/10.7150/thno.4922
    • (2013) Theranostics , vol.3 , pp. 26-33
    • Wald, O.1    Shapira, O.M.2    Izhar, U.3
  • 11
    • 11144238568 scopus 로고    scopus 로고
    • Expression and functional role of CCR9 in prostate cancer cell migration and invasion
    • 15623660
    • S.Singh, U.P.Singh, J.K.Stiles, W.E.Grizzle, J.W.Lillard, Jr. Expression and functional role of CCR9 in prostate cancer cell migration and invasion. Clin Cancer Res: Off J Am Assoc Cancer Res 2004; 10:8743-50; PMID:15623660; http://dx.doi.org/10.1158/1078-0432.CCR-04-0266
    • (2004) Clin Cancer Res: Off J Am Assoc Cancer Res , vol.10 , pp. 8743-8750
    • Singh, S.1    Singh, U.P.2    Stiles, J.K.3    Grizzle, W.E.4    Lillard, J.W.5
  • 12
    • 3142666166 scopus 로고    scopus 로고
    • CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells
    • 15256432
    • S.A.Shulby, N.G.Dolloff, M.E.Stearns, O.Meucci, A.Fatatis. CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells. Cancer Res 2004; 64:4693-8; PMID:15256432; http://dx.doi.org/10.1158/0008-5472.CAN-03-3437
    • (2004) Cancer Res , vol.64 , pp. 4693-4698
    • Shulby, S.A.1    Dolloff, N.G.2    Stearns, M.E.3    Meucci, O.4    Fatatis, A.5
  • 13
    • 72749094682 scopus 로고    scopus 로고
    • Emerging roles of chemokines in prostate cancer
    • 19556286
    • D.Vindrieux, P.Escobar, G.Lazennec. Emerging roles of chemokines in prostate cancer. Endocr-Relat Cancer 2009; 16:663-73; PMID:19556286; http://dx.doi.org/10.1677/ERC-09-0109
    • (2009) Endocr-Relat Cancer , vol.16 , pp. 663-673
    • Vindrieux, D.1    Escobar, P.2    Lazennec, G.3
  • 15
    • 84902536339 scopus 로고    scopus 로고
    • Expression of CXCR4 and breast cancer prognosis: a systematic review and meta-analysis
    • 24475985
    • Z.Zhang, C.Ni, W.Chen, P.Wu, Z.Wang, J.Yin, J.Huang, F.Qiu. Expression of CXCR4 and breast cancer prognosis: a systematic review and meta-analysis. BMC Cancer 2014; 14:49; PMID:24475985; http://dx.doi.org/10.1186/1471-2407-14-49
    • (2014) BMC Cancer , vol.14 , pp. 49
    • Zhang, Z.1    Ni, C.2    Chen, W.3    Wu, P.4    Wang, Z.5    Yin, J.6    Huang, J.7    Qiu, F.8
  • 16
    • 33746051169 scopus 로고    scopus 로고
    • Chemokines, chemokine receptors, and cancer metastasis
    • 16478915
    • T.Kakinuma, S.T.Hwang. Chemokines, chemokine receptors, and cancer metastasis. J Leukoc Biol 2006; 79:639-51; PMID:16478915; http://dx.doi.org/10.1189/jlb.1105633
    • (2006) J Leukoc Biol , vol.79 , pp. 639-651
    • Kakinuma, T.1    Hwang, S.T.2
  • 17
    • 79960017581 scopus 로고    scopus 로고
    • Expression and histopathological correlation of CCR9 and CCL25 in ovarian cancer
    • 21637913
    • R.Singh, C.R.Stockard, W.E.Grizzle, J.W.Lillard, Jr., S.Singh. Expression and histopathological correlation of CCR9 and CCL25 in ovarian cancer. Int J Oncol 2011; 39:373-81; PMID:21637913
    • (2011) Int J Oncol , vol.39 , pp. 373-381
    • Singh, R.1    Stockard, C.R.2    Grizzle, W.E.3    Lillard, J.W.4    Singh, S.5
  • 18
    • 39549096664 scopus 로고    scopus 로고
    • Amelioratory effect of andrographis paniculata nees on liver, kidney, heart, lung and spleen during nicotine induced oxidative stress
    • 21783869
    • S.Neogy, S.Das, S.K.Mahapatra, N.Mandal, S.Roy. Amelioratory effect of andrographis paniculata nees on liver, kidney, heart, lung and spleen during nicotine induced oxidative stress. Environ Toxicol Pharmacol 2008; 25:321-8; PMID:21783869; http://dx.doi.org/10.1016/j.etap.2007.10.034
    • (2008) Environ Toxicol Pharmacol , vol.25 , pp. 321-328
    • Neogy, S.1    Das, S.2    Mahapatra, S.K.3    Mandal, N.4    Roy, S.5
  • 19
    • 33947607132 scopus 로고    scopus 로고
    • Protective activity of andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol-induced toxicity in mice
    • P.K.Singha, S.Roy, S.Dey. Protective activity of andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol-induced toxicity in mice. J Ethnopharmacol 2007; 111:13–21.
    • (2007) J Ethnopharmacol , vol.111 , pp. 13-21
    • Singha, P.K.1    Roy, S.2    Dey, S.3
  • 20
    • 48849109817 scopus 로고    scopus 로고
    • Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide
    • 18619950
    • M.-D.Shi, H.-H.Lin, Y.-C.Lee, J.-K.Chao, R.-A.Lin, J.-H.Chen. Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide. Chemico-Biological Interactions 2008; 174:201-10; PMID:18619950; http://dx.doi.org/10.1016/j.cbi.2008.06.006
    • (2008) Chemico-Biological Interactions , vol.174 , pp. 201-210
    • Shi, M.-D.1    Lin, H.-H.2    Lee, Y.-C.3    Chao, J.-K.4    Lin, R.-A.5    Chen, J.-H.6
  • 22
    • 0032931766 scopus 로고    scopus 로고
    • Cyclin E2, a novel G1 cyclin that binds Cdk2 and is aberrantly expressed in human cancers
    • 9858585
    • J.M.Gudas, M.Payton, S.Thukral, E.Chen, M.Bass, M.O.Robinson, S.Coats. Cyclin E2, a novel G1 cyclin that binds Cdk2 and is aberrantly expressed in human cancers. Mol Cell Biol 1999; 19:612-22; PMID:9858585; http://dx.doi.org/10.1128/MCB.19.1.612
    • (1999) Mol Cell Biol , vol.19 , pp. 612-622
    • Gudas, J.M.1    Payton, M.2    Thukral, S.3    Chen, E.4    Bass, M.5    Robinson, M.O.6    Coats, S.7
  • 24
    • 80052811947 scopus 로고    scopus 로고
    • Andrographolide inhibits oral squamous cell carcinogenesis through NF-kappaB inactivation
    • 21841043
    • L.J.Wang, X.Zhou, W.Wang, F.Tang, C.L.Qi, X.Yang, S.Wu, Y.Q.Lin, J.T.Wang, J.G.Geng. Andrographolide inhibits oral squamous cell carcinogenesis through NF-kappaB inactivation. J Dent Res 2011; 90:1246-52; PMID:21841043; http://dx.doi.org/10.1177/0022034511418341
    • (2011) J Dent Res , vol.90 , pp. 1246-1252
    • Wang, L.J.1    Zhou, X.2    Wang, W.3    Tang, F.4    Qi, C.L.5    Yang, X.6    Wu, S.7    Lin, Y.Q.8    Wang, J.T.9    Geng, J.G.10
  • 25
    • 84923233767 scopus 로고    scopus 로고
    • Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3beta: autoregulation of GSK-3beta in vivo
    • 25423492
    • C.Tapia-Rojas, A.Schuller, C.B.Lindsay, R.C.Ureta, C.Mejias-Reyes, J.Hancke, F.Melo, N.C.Inestrosa. Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3beta: autoregulation of GSK-3beta in vivo. Biochem J 2015; 466:415-30; PMID:25423492; http://dx.doi.org/10.1042/BJ20140207
    • (2015) Biochem J , vol.466 , pp. 415-430
    • Tapia-Rojas, C.1    Schuller, A.2    Lindsay, C.B.3    Ureta, R.C.4    Mejias-Reyes, C.5    Hancke, J.6    Melo, F.7    Inestrosa, N.C.8
  • 26
    • 0142068802 scopus 로고    scopus 로고
    • Cyclin-dependent kinases and S phase control in mammalian cells
    • 12851482
    • R.A.Woo, R.Y.Poon. Cyclin-dependent kinases and S phase control in mammalian cells. Cell cycle (Georgetown, Tex) 2003; 2:316-24; PMID:12851482; http://dx.doi.org/10.4161/cc.2.4.468
    • (2003) Cell cycle (Georgetown, Tex) , vol.2 , pp. 316-324
    • Woo, R.A.1    Poon, R.Y.2
  • 28
    • 0028980058 scopus 로고
    • Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer
    • 7539916
    • A.Dutta, R.Chandra, L.M.Leiter, S.Lester. Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer. Proc Nat Acad SciU S A 1995; 92:5386-90; PMID:7539916; http://dx.doi.org/10.1073/pnas.92.12.5386
    • (1995) Proc Nat Acad SciU S A , vol.92 , pp. 5386-5390
    • Dutta, A.1    Chandra, R.2    Leiter, L.M.3    Lester, S.4
  • 29
    • 31544483104 scopus 로고    scopus 로고
    • Evaluation of anticyclin B1 serum antibody as a diagnostic and prognostic biomarker for lung cancer
    • 16461786
    • A.M.Egloff, J.Weissfeld, S.R.Land, O.J.Finn. Evaluation of anticyclin B1 serum antibody as a diagnostic and prognostic biomarker for lung cancer. AnnNew York Acad Sci 2005; 1062:29-40; PMID:16461786; http://dx.doi.org/10.1196/annals.1358.005
    • (2005) AnnNew York Acad Sci , vol.1062 , pp. 29-40
    • Egloff, A.M.1    Weissfeld, J.2    Land, S.R.3    Finn, O.J.4
  • 31
    • 84871787545 scopus 로고    scopus 로고
    • Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retina
    • 23301080
    • I.M.Ornelas, T.M.Silva, L.Fragel-Madeira, A.L.M.Ventura Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retina. PloS one 2013; 8:e53517; PMID:23301080; http://dx.doi.org/10.1371/journal.pone.0053517
    • (2013) PloS one , vol.8 , pp. e53517
    • Ornelas, I.M.1    Silva, T.M.2    Fragel-Madeira, L.3    Ventura, A.L.M.4
  • 32
    • 84863336678 scopus 로고    scopus 로고
    • Inactivation of PI3K/Akt signaling mediates proliferation inhibition and G2/M phase arrest induced by andrographolide in human glioblastoma cells
    • AMBIGUOUS
    • Y.Li, P.Zhang, F.Qiu, L.Chen, C.Miao, J.Li, W.Xiao, E.Ma. Inactivation of PI3K/Akt signaling mediates proliferation inhibition and G2/M phase arrest induced by andrographolide in human glioblastoma cells. Life Sci 2012; 90:962-7; PMID:AMBIGUOUS; http://dx.doi.org/10.1016/j.lfs.2012.04.044
    • (2012) Life Sci , vol.90 , pp. 962-967
    • Li, Y.1    Zhang, P.2    Qiu, F.3    Chen, L.4    Miao, C.5    Li, J.6    Xiao, W.7    Ma, E.8
  • 33
    • 77956701109 scopus 로고    scopus 로고
    • The Roles of Cyclin A2, B1, and B2 in Early and Late Mitotic Events
    • 20660152
    • D.Gong, J.E.Ferrell. The Roles of Cyclin A2, B1, and B2 in Early and Late Mitotic Events. Mol Biol Cell 2010; 21:3149-61; PMID:20660152; http://dx.doi.org/10.1091/mbc.E10-05-0393
    • (2010) Mol Biol Cell , vol.21 , pp. 3149-3161
    • Gong, D.1    Ferrell, J.E.2
  • 34
    • 34248184018 scopus 로고    scopus 로고
    • Specialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factor
    • 17344473
    • T.K.Fung, H.T.Ma, R.Y.Poon. Specialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factor. Mol Biol Cell 2007; 18:1861-73; PMID:17344473; http://dx.doi.org/10.1091/mbc.E06-12-1092
    • (2007) Mol Biol Cell , vol.18 , pp. 1861-1873
    • Fung, T.K.1    Ma, H.T.2    Poon, R.Y.3
  • 35
    • 79953175974 scopus 로고    scopus 로고
    • Andrographolide enhances nuclear factor-kappaB subunit p65 Ser536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells
    • C.Y.Hsieh, M.J.Hsu, G.Hsiao, Y.H.Wang, C.W.Huang, S.W.Chen, T.Jayakumar, P.T.Chiu, Y.H.Chiu, J.R.Sheu. Andrographolide enhances nuclear factor-kappaB subunit p65 Ser536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells. J Biol Chem 2011; 286:5942–55.
    • (2011) J Biol Chem , vol.286 , pp. 5942-5955
    • Hsieh, C.Y.1    Hsu, M.J.2    Hsiao, G.3    Wang, Y.H.4    Huang, C.W.5    Chen, S.W.6    Jayakumar, T.7    Chiu, P.T.8    Chiu, Y.H.9    Sheu, J.R.10
  • 36
    • 0043066731 scopus 로고    scopus 로고
    • Regulating mammalian checkpoints through Cdc25 inactivation
    • 12835754
    • M.Donzelli, G.F.Draetta. Regulating mammalian checkpoints through Cdc25 inactivation. EMBO reports 2003; 4:671-7; PMID:12835754; http://dx.doi.org/10.1038/sj.embor.embor887
    • (2003) EMBO reports , vol.4 , pp. 671-677
    • Donzelli, M.1    Draetta, G.F.2
  • 37
    • 0028838971 scopus 로고
    • Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling
    • 7834742
    • T.Hunter Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 1995; 80:225-36; PMID:7834742; http://dx.doi.org/10.1016/0092-8674(95)90405-0
    • (1995) Cell , vol.80 , pp. 225-236
    • Hunter, T.1
  • 39
    • 84859877994 scopus 로고    scopus 로고
    • Developing S-phase control
    • 22508722
    • R.J.Duronio Developing S-phase control. Genes Dev 2012; 26:746-50; PMID:22508722; http://dx.doi.org/10.1101/gad.191171.112
    • (2012) Genes Dev , vol.26 , pp. 746-750
    • Duronio, R.J.1
  • 40
    • 13844269240 scopus 로고    scopus 로고
    • p21 stability: linking chaperones to a cell cycle checkpoint
    • G.Liu, G.Lozano. p21 stability: linking chaperones to a cell cycle checkpoint. Cancer Cell 2005; 7:113–4.
    • (2005) Cancer Cell , vol.7 , pp. 113-114
    • Liu, G.1    Lozano, G.2
  • 42
    • 84892373230 scopus 로고    scopus 로고
    • Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy
    • S.H.Liu, C.H.Lin, F.P.Liang, P.F.Chen, C.D.Kuo, M.M.Alam, B.Maiti, S.K.Hung, C.W.Chi, C.M.Sun, Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy. Biochem Pharmacol 2014; 87:229–42.
    • (2014) Biochem Pharmacol , vol.87 , pp. 229-242
    • Liu, S.H.1    Lin, C.H.2    Liang, F.P.3    Chen, P.F.4    Kuo, C.D.5    Alam, M.M.6    Maiti, B.7    Hung, S.K.8    Chi, C.W.9    Sun, C.M.10
  • 44
    • 33646543052 scopus 로고    scopus 로고
    • CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation
    • 16339779
    • M.O.Aksoy, Y.Yang, R.Ji, P.J.Reddy, S.Shahabuddin, J.Litvin, T.J.Rogers, S.G.Kelsen. CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation. Am J Physiol Lung Cell Mol Physiol 2006; 290:L909-18; PMID:16339779; http://dx.doi.org/10.1152/ajplung.00430.2005
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290 , pp. L909-L918
    • Aksoy, M.O.1    Yang, Y.2    Ji, R.3    Reddy, P.J.4    Shahabuddin, S.5    Litvin, J.6    Rogers, T.J.7    Kelsen, S.G.8
  • 45
    • 0010136245 scopus 로고    scopus 로고
    • Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha
    • 8798467
    • M.R.Rani, G.R.Foster, S.Leung, D.Leaman, G.R.Stark, R.M.Ransohoff. Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha. J Biol Chem 1996; 271:22878-84; PMID:8798467; http://dx.doi.org/10.1074/jbc.271.37.22878
    • (1996) J Biol Chem , vol.271 , pp. 22878-22884
    • Rani, M.R.1    Foster, G.R.2    Leung, S.3    Leaman, D.4    Stark, G.R.5    Ransohoff, R.M.6
  • 46
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • 6606682
    • T.Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Meth 1983; 65:55-63; PMID:6606682; http://dx.doi.org/10.1016/0022-1759(83)90303-4
    • (1983) J Immunol Meth , vol.65 , pp. 55-63
    • Mosmann, T.1


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