-
3
-
-
77953609646
-
Serine proteases of the human immune system in health and disease
-
Heutinck K., ten Berge I., Hack C., Hamann J., Rowshani A. Serine proteases of the human immune system in health and disease. Mol. Immunol. 2010, 47:1943-1955.
-
(2010)
Mol. Immunol.
, vol.47
, pp. 1943-1955
-
-
Heutinck, K.1
ten Berge, I.2
Hack, C.3
Hamann, J.4
Rowshani, A.5
-
4
-
-
11244297746
-
The cardiovascular actions of protease-activated receptors
-
Steinberg S.F. The cardiovascular actions of protease-activated receptors. Mol. Pharmacol. 2005, 67:2-11.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 2-11
-
-
Steinberg, S.F.1
-
5
-
-
79955584619
-
Structure, function and pathophysiology of protease activated receptors
-
Adams M.N., Ramachandran R., Yau M.-K., Suen J.Y., Fairlie D.P., Hollenberg M.D., et al. Structure, function and pathophysiology of protease activated receptors. Pharmacol. Ther. 2011, 130:248-282.
-
(2011)
Pharmacol. Ther.
, vol.130
, pp. 248-282
-
-
Adams, M.N.1
Ramachandran, R.2
Yau, M.-K.3
Suen, J.Y.4
Fairlie, D.P.5
Hollenberg, M.D.6
-
6
-
-
0033613183
-
How the protease thrombin talks to cells
-
Coughlin S.R. How the protease thrombin talks to cells. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:11023-11027.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11023-11027
-
-
Coughlin, S.R.1
-
7
-
-
0034648757
-
Thrombin signalling and protease-activated receptors
-
Coughlin S.R. Thrombin signalling and protease-activated receptors. Nature 2000, 407:258-264.
-
(2000)
Nature
, vol.407
, pp. 258-264
-
-
Coughlin, S.R.1
-
8
-
-
0037144657
-
Protease-activated receptor-1-mediated DNA synthesis in cardiac fibroblast is via epidermal growth factor receptor transactivation: distinct PAR-1 signaling pathways in cardiac fibroblasts and cardiomyocytes
-
Sabri A., Short J., Guo J., Steinberg S.F. Protease-activated receptor-1-mediated DNA synthesis in cardiac fibroblast is via epidermal growth factor receptor transactivation: distinct PAR-1 signaling pathways in cardiac fibroblasts and cardiomyocytes. Circ. Res. 2002, 91:532-539.
-
(2002)
Circ. Res.
, vol.91
, pp. 532-539
-
-
Sabri, A.1
Short, J.2
Guo, J.3
Steinberg, S.F.4
-
9
-
-
0032514474
-
A dual thrombin receptor system for platelet activation
-
Kahn M.L., Zheng Y.-W., Huang W., Bigornia V., Zeng D., Moff S., et al. A dual thrombin receptor system for platelet activation. Nature 1998, 394:690-694.
-
(1998)
Nature
, vol.394
, pp. 690-694
-
-
Kahn, M.L.1
Zheng, Y.-W.2
Huang, W.3
Bigornia, V.4
Zeng, D.5
Moff, S.6
-
10
-
-
36048945107
-
Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy
-
Pawlinski R., Tencati M., Hampton C.R., Shishido T., Bullard T.A., Casey L.M., et al. Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy. Circulation 2007, 116:2298-2306.
-
(2007)
Circulation
, vol.116
, pp. 2298-2306
-
-
Pawlinski, R.1
Tencati, M.2
Hampton, C.R.3
Shishido, T.4
Bullard, T.A.5
Casey, L.M.6
-
11
-
-
1842791710
-
Trypsin IV, a novel agonist of protease-activated receptors 2 and 4
-
Cottrell G.S., Amadesi S., Grady E.F., Bunnett N.W. Trypsin IV, a novel agonist of protease-activated receptors 2 and 4. J. Biol. Chem. 2004, 279:13532-13539.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13532-13539
-
-
Cottrell, G.S.1
Amadesi, S.2
Grady, E.F.3
Bunnett, N.W.4
-
12
-
-
33845955449
-
Proteinase-activated receptors, targets for kallikrein signaling
-
Oikonomopoulou K., Hansen K.K., Saifeddine M., Tea I., Blaber M., Blaber S.I., et al. Proteinase-activated receptors, targets for kallikrein signaling. J. Biol. Chem. 2006, 281:32095-32112.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 32095-32112
-
-
Oikonomopoulou, K.1
Hansen, K.K.2
Saifeddine, M.3
Tea, I.4
Blaber, M.5
Blaber, S.I.6
-
13
-
-
0034629468
-
Cathepsin G activates protease-activated receptor-4 in human platelets
-
Sambrano G.R., Huang W., Faruqi T., Mahrus S., Craik C., Coughlin S.R. Cathepsin G activates protease-activated receptor-4 in human platelets. J. Biol. Chem. 2000, 275:6819-6823.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6819-6823
-
-
Sambrano, G.R.1
Huang, W.2
Faruqi, T.3
Mahrus, S.4
Craik, C.5
Coughlin, S.R.6
-
14
-
-
13244273430
-
Impaired hemostasis and protection against thrombosis in protease-activated receptor 4-deficient mice is due to lack of thrombin signaling in platelets
-
Hamilton J.R., Cornelissen I., Coughlin S.R. Impaired hemostasis and protection against thrombosis in protease-activated receptor 4-deficient mice is due to lack of thrombin signaling in platelets. J. Thromb. Haemost. 2004, 2:1429-1435.
-
(2004)
J. Thromb. Haemost.
, vol.2
, pp. 1429-1435
-
-
Hamilton, J.R.1
Cornelissen, I.2
Coughlin, S.R.3
-
15
-
-
0035817822
-
Role of thrombin signalling in platelets in haemostasis and thrombosis
-
Sambrano G.R., Weiss E.J., Zheng Y.-W., Huang W., Coughlin S.R. Role of thrombin signalling in platelets in haemostasis and thrombosis. Nature 2001, 413:74-78.
-
(2001)
Nature
, vol.413
, pp. 74-78
-
-
Sambrano, G.R.1
Weiss, E.J.2
Zheng, Y.-W.3
Huang, W.4
Coughlin, S.R.5
-
16
-
-
7544230083
-
Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo
-
Hollenberg M.D., Saifeddine M., Sandhu S., Houle S., Vergnolle N. Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br. J. Pharmacol. 2004, 143:443-454.
-
(2004)
Br. J. Pharmacol.
, vol.143
, pp. 443-454
-
-
Hollenberg, M.D.1
Saifeddine, M.2
Sandhu, S.3
Houle, S.4
Vergnolle, N.5
-
17
-
-
0036681940
-
Characterization of thrombin-induced leukocyte rolling and adherence: a potential proinflammatory role for proteinase-activated receptor-4
-
Vergnolle N., Derian C.K., D'Andrea M.R., Steinhoff M., Andrade-Gordon P. Characterization of thrombin-induced leukocyte rolling and adherence: a potential proinflammatory role for proteinase-activated receptor-4. J. Immunol. 2002, 169:1467-1473.
-
(2002)
J. Immunol.
, vol.169
, pp. 1467-1473
-
-
Vergnolle, N.1
Derian, C.K.2
D'Andrea, M.R.3
Steinhoff, M.4
Andrade-Gordon, P.5
-
18
-
-
0037900130
-
Mechanisms of protease-activated receptor-4 actions in cardiomyocytes. Role of Src tyrosine kinase
-
Sabri A., Guo J., Elouardighi H., Darrow A.L., Andrade-Gordon P., Steinberg S.F. Mechanisms of protease-activated receptor-4 actions in cardiomyocytes. Role of Src tyrosine kinase. J. Biol. Chem. 2003, 278:11714-11720.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11714-11720
-
-
Sabri, A.1
Guo, J.2
Elouardighi, H.3
Darrow, A.L.4
Andrade-Gordon, P.5
Steinberg, S.F.6
-
19
-
-
40849113307
-
Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling
-
Strande J.L., Hsu A., Su J., Fu X., Gross G.J., Baker J.E. Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling. J. Pharmacol. Exp. Ther. 2008, 324:1045-1054.
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.324
, pp. 1045-1054
-
-
Strande, J.L.1
Hsu, A.2
Su, J.3
Fu, X.4
Gross, G.J.5
Baker, J.E.6
-
20
-
-
0029147782
-
Induction of interleukin-6 synthesis in the myocardium: potential role in postreperfusion inflammatory injury
-
Kukielka G.L., Smith C.W., Manning A.M., Youker K.A., Michael L.H., Entman M.L. Induction of interleukin-6 synthesis in the myocardium: potential role in postreperfusion inflammatory injury. Circulation 1995, 92:1866-1875.
-
(1995)
Circulation
, vol.92
, pp. 1866-1875
-
-
Kukielka, G.L.1
Smith, C.W.2
Manning, A.M.3
Youker, K.A.4
Michael, L.H.5
Entman, M.L.6
-
21
-
-
0035497740
-
Neutralization of interleukin-1β in the acute phase of myocardial infarction promotes the progression of left ventricular remodeling
-
Hwang M.-W., Matsumori A., Furukawa Y., Ono K., Okada M., Iwasaki A., et al. Neutralization of interleukin-1β in the acute phase of myocardial infarction promotes the progression of left ventricular remodeling. J. Am. Coll. Cardiol. 2001, 38:1546-1553.
-
(2001)
J. Am. Coll. Cardiol.
, vol.38
, pp. 1546-1553
-
-
Hwang, M.-W.1
Matsumori, A.2
Furukawa, Y.3
Ono, K.4
Okada, M.5
Iwasaki, A.6
-
22
-
-
0034717192
-
Signaling properties and functions of two distinct cardiomyocyte protease-activated receptors
-
Sabri A., Muske G., Zhang H., Pak E., Darrow A., Andrade-Gordon P., et al. Signaling properties and functions of two distinct cardiomyocyte protease-activated receptors. Circ. Res. 2000, 86:1054-1061.
-
(2000)
Circ. Res.
, vol.86
, pp. 1054-1061
-
-
Sabri, A.1
Muske, G.2
Zhang, H.3
Pak, E.4
Darrow, A.5
Andrade-Gordon, P.6
-
23
-
-
0032499696
-
Cloning and characterization of human protease-activated receptor-4
-
Xu W.F., Andersen H., Whitmore T.E., Presnell S.R., Yee D.P., Ching A., et al. Cloning and characterization of human protease-activated receptor-4. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:6642-6646.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6642-6646
-
-
Xu, W.F.1
Andersen, H.2
Whitmore, T.E.3
Presnell, S.R.4
Yee, D.P.5
Ching, A.6
-
24
-
-
11144307292
-
Stress signaling pathways that modulate cardiac myocyte apoptosis
-
Baines C.P., Molkentin J.D. Stress signaling pathways that modulate cardiac myocyte apoptosis. J. Mol. Cell. Cardiol. 2005, 38:47-62.
-
(2005)
J. Mol. Cell. Cardiol.
, vol.38
, pp. 47-62
-
-
Baines, C.P.1
Molkentin, J.D.2
-
25
-
-
0036152858
-
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy
-
Asakura M., Kitakaze M., Takashima S., Liao Y., Ishikura F., Yoshinaka T., et al. Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nat. Med. 2002, 8:35-40.
-
(2002)
Nat. Med.
, vol.8
, pp. 35-40
-
-
Asakura, M.1
Kitakaze, M.2
Takashima, S.3
Liao, Y.4
Ishikura, F.5
Yoshinaka, T.6
-
26
-
-
33947282669
-
Platelet-neutrophil-interactions: linking hemostasis and inflammation
-
Zarbock A., Polanowska-Grabowska R.K., Ley K. Platelet-neutrophil-interactions: linking hemostasis and inflammation. Blood Rev. 2007, 21:99-111.
-
(2007)
Blood Rev.
, vol.21
, pp. 99-111
-
-
Zarbock, A.1
Polanowska-Grabowska, R.K.2
Ley, K.3
-
27
-
-
0036533649
-
Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
-
Asokananthan N., Graham P.T., Fink J., Knight D.A., Bakker A.J., McWilliam A.S., et al. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J. Immunol. 2002, 168:3577-3585.
-
(2002)
J. Immunol.
, vol.168
, pp. 3577-3585
-
-
Asokananthan, N.1
Graham, P.T.2
Fink, J.3
Knight, D.A.4
Bakker, A.J.5
McWilliam, A.S.6
-
28
-
-
4444234050
-
A paradoxical pro-apoptotic effect of thrombin on smooth muscle cells
-
Rossignol P., Bouton M.-C., Jandrot-Perrus M., Bryckaert M., Jacob M.-P., Bezeaud A., et al. A paradoxical pro-apoptotic effect of thrombin on smooth muscle cells. Exp. Cell Res. 2004, 299:279-285.
-
(2004)
Exp. Cell Res.
, vol.299
, pp. 279-285
-
-
Rossignol, P.1
Bouton, M.-C.2
Jandrot-Perrus, M.3
Bryckaert, M.4
Jacob, M.-P.5
Bezeaud, A.6
-
29
-
-
79551696812
-
Induction of apoptosis by thrombin in the cultured neurons of dorsal motor nucleus of the vagus
-
279-e124
-
Wu X., Zhang W., Li J.-Y., Chai B.-X., Peng J., Wang H., et al. Induction of apoptosis by thrombin in the cultured neurons of dorsal motor nucleus of the vagus. Neurogastroenterol. Motil. 2011, 23:279-e124.
-
(2011)
Neurogastroenterol. Motil.
, vol.23
-
-
Wu, X.1
Zhang, W.2
Li, J.-Y.3
Chai, B.-X.4
Peng, J.5
Wang, H.6
-
30
-
-
0036033424
-
Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors
-
Seifert R., Wenzel-Seifert K. Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors. Naunyn Schmiedeberg's Arch. Pharmacol. 2002, 366:381-416.
-
(2002)
Naunyn Schmiedeberg's Arch. Pharmacol.
, vol.366
, pp. 381-416
-
-
Seifert, R.1
Wenzel-Seifert, K.2
-
31
-
-
0037012652
-
Dual actions of the Galpha(q) agonist Pasteurella multocida toxin to promote cardiomyocyte hypertrophy and enhance apoptosis susceptibility
-
Sabri A., Wilson B.A., Steinberg S.F. Dual actions of the Galpha(q) agonist Pasteurella multocida toxin to promote cardiomyocyte hypertrophy and enhance apoptosis susceptibility. Circ. Res. 2002, 90:850-857.
-
(2002)
Circ. Res.
, vol.90
, pp. 850-857
-
-
Sabri, A.1
Wilson, B.A.2
Steinberg, S.F.3
-
32
-
-
0037117639
-
Statin prevents tissue factor expression in human endothelial cells: role of Rho/Rho-kinase and Akt pathways
-
Eto M., Kozai T., Cosentino F., Joch H., Lüscher T.F. Statin prevents tissue factor expression in human endothelial cells: role of Rho/Rho-kinase and Akt pathways. Circulation 2002, 105:1756-1759.
-
(2002)
Circulation
, vol.105
, pp. 1756-1759
-
-
Eto, M.1
Kozai, T.2
Cosentino, F.3
Joch, H.4
Lüscher, T.F.5
-
33
-
-
33644841906
-
C-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo
-
Shao Z., Bhattacharya K., Hsich E., Park L., Walters B., Germann U., et al. c-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo. Circ. Res. 2006, 98:111-118.
-
(2006)
Circ. Res.
, vol.98
, pp. 111-118
-
-
Shao, Z.1
Bhattacharya, K.2
Hsich, E.3
Park, L.4
Walters, B.5
Germann, U.6
-
34
-
-
25444482606
-
Genetic inhibition or activation of JNK1/2 protects the myocardium from ischemia-reperfusion-induced cell death in vivo
-
Kaiser R.A., Liang Q., Bueno O., Huang Y., Lackey T., Klevitsky R., et al. Genetic inhibition or activation of JNK1/2 protects the myocardium from ischemia-reperfusion-induced cell death in vivo. J. Biol. Chem. 2005, 280:32602-32608.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32602-32608
-
-
Kaiser, R.A.1
Liang, Q.2
Bueno, O.3
Huang, Y.4
Lackey, T.5
Klevitsky, R.6
-
35
-
-
37849053036
-
Novel mode for neutrophil protease cathepsin G-mediated signaling: membrane shedding of epidermal growth factor is required for cardiomyocyte anoikis
-
Rafiq K., Hanscom M., Valerie K., Steinberg S., Sabri A. Novel mode for neutrophil protease cathepsin G-mediated signaling: membrane shedding of epidermal growth factor is required for cardiomyocyte anoikis. Circ. Res. 2008, 102:32-41.
-
(2008)
Circ. Res.
, vol.102
, pp. 32-41
-
-
Rafiq, K.1
Hanscom, M.2
Valerie, K.3
Steinberg, S.4
Sabri, A.5
-
36
-
-
34250342563
-
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts
-
Strande J.L., Hsu A., Su J., Fu X., Gross G.J., Baker J.E. SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts. Basic Res. Cardiol. 2007, 102:350-358.
-
(2007)
Basic Res. Cardiol.
, vol.102
, pp. 350-358
-
-
Strande, J.L.1
Hsu, A.2
Su, J.3
Fu, X.4
Gross, G.J.5
Baker, J.E.6
-
37
-
-
0034682810
-
Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin
-
Shapiro M.J., Weiss E.J., Faruqi T.R., Coughlin S.R. Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin. J. Biol. Chem. 2000, 275:25216-25221.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25216-25221
-
-
Shapiro, M.J.1
Weiss, E.J.2
Faruqi, T.R.3
Coughlin, S.R.4
|