Protease-activated receptor-1-mediated DNA synthesis in cardiac fibroblast is via epidermal growth factor receptor transactivation: Distinct PAR-1 signaling pathways in cardiac fibroblasts and cardiomyocytes

Circulation Research

Volumn 91, Issue 6, 2002, Pages 532-539

  Sabri, Abdelkarim ^a   Short, Jacob ^a   Guo, Jianfen ^a   Steinberg, Susan F ^a  

^a Columbia University ^*  (United States)

Author keywords

Cardiac fibroblasts; Epidermal growth factor receptors; Protease activated receptors; Signal transduction; Thrombin

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; FIBROBLAST; HEART MUSCLE CELL; INFLAMMATORY CELL; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FIBROBLASTS; HEART VENTRICLES; PEPTIDE FRAGMENTS; PERTUSSIS TOXIN; PHOSPHOLIPASE C; PYRAZOLES; PYRIMIDINES; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; THROMBIN;

EID: 0037144657     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000035242.96310.45     Document Type: Article

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