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Volumn 26, Issue 7, 2016, Pages 324-333

A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studies

Author keywords

cholesterol; dyslipidemia; fenofibrate; genome wide association study; lipid; lipoprotein; triglyceride

Indexed keywords

FENOFIBRATE; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTILIPEMIC AGENT; GENETIC MARKER;

EID: 84961393542     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0000000000000219     Document Type: Article
Times cited : (13)

References (46)
  • 1
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among us adults: Findings from the third national health and nutrition examination survey
    • Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002; 287: 356-359.
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 2
    • 0031861930 scopus 로고    scopus 로고
    • Plasma triglyceride as a risk factor for cardiovascular disease
    • Suppl B
    • Austin MA. Plasma triglyceride as a risk factor for cardiovascular disease. Can J Cardiol 1998; 14 (Suppl B): 14B-17B.
    • (1998) Can J Cardiol , vol.14 , pp. 14B-17B
    • Austin, M.A.1
  • 6
    • 84906259943 scopus 로고    scopus 로고
    • Triglycerides and cardiovascular disease
    • Nordestgaard BG, Varbo A. Triglycerides and cardiovascular disease. Lancet 2014; 384: 626-635.
    • (2014) Lancet , vol.384 , pp. 626-635
    • Nordestgaard, B.G.1    Varbo, A.2
  • 7
    • 84921963597 scopus 로고    scopus 로고
    • Triglyceride-rich lipoproteins and coronary artery disease risk: New insights from human genetics
    • Khetarpal SA, Rader DJ. Triglyceride-rich lipoproteins and coronary artery disease risk: new insights from human genetics. Arterioscler Thromb Vasc Biol 2015; 35: e3-e9.
    • (2015) Arterioscler Thromb Vasc Biol , vol.35 , pp. e3-e9
    • Khetarpal, S.A.1    Rader, D.J.2
  • 8
    • 63449138395 scopus 로고    scopus 로고
    • Database mining for selection of SNP markers useful in admixture mapping
    • Baye TM, Tiwari HK, Allison DB, Go RC. Database mining for selection of SNP markers useful in admixture mapping. BioData Min 2009; 2: 1.
    • (2009) BioData Min , vol.2 , pp. 1
    • Baye, T.M.1    Tiwari, H.K.2    Allison, D.B.3    Go, R.C.4
  • 9
    • 0344874601 scopus 로고    scopus 로고
    • Fibrates in 2003: Therapeutic action in atherogenic dyslipidaemia and future perspectives
    • Chapman MJ. Fibrates in 2003: therapeutic action in atherogenic dyslipidaemia and future perspectives. Atherosclerosis 2003; 171: 1-13.
    • (2003) Atherosclerosis , vol.171 , pp. 1-13
    • Chapman, M.J.1
  • 10
    • 24644447956 scopus 로고    scopus 로고
    • Fibrates and coronary risk reduction
    • Steiner G. Fibrates and coronary risk reduction. Atherosclerosis 2005; 182: 199-207.
    • (2005) Atherosclerosis , vol.182 , pp. 199-207
    • Steiner, G.1
  • 11
    • 5144227019 scopus 로고    scopus 로고
    • The role of fibrates in managing hyperlipidemia: Mechanisms of action and clinical efficacy
    • Fazio S, Linton MF. The role of fibrates in managing hyperlipidemia: mechanisms of action and clinical efficacy. Curr Atheroscler Rep 2004; 6: 148-157.
    • (2004) Curr Atheroscler Rep , vol.6 , pp. 148-157
    • Fazio, S.1    Linton, M.F.2
  • 12
    • 0029941224 scopus 로고    scopus 로고
    • Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalizes the atherogenic, dense LDL profile in combined hyperlipidemia
    • Guerin M, Bruckert E, Dolphin PJ, Turpin G, Chapman MJ. Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalizes the atherogenic, dense LDL profile in combined hyperlipidemia. Arterioscler Thromb Vasc Biol 1996; 16: 763-772.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 763-772
    • Guerin, M.1    Bruckert, E.2    Dolphin, P.J.3    Turpin, G.4    Chapman, M.J.5
  • 13
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary-prevention trial with gemfibrozil in middle-Aged men with dyslipidemia Safety of treatment, changes in risk factors, and incidence of coronary heart disease
    • Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-Aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987; 317: 1237-1245.
    • (1987) N Engl J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3    Heinonen, O.P.4    Heinsalmi, P.5    Helo, P.6
  • 14
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol
    • Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
    • Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med 1999; 341: 410-418.
    • (1999) N Engl J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3    Fye, C.L.4    Anderson, J.W.5    Elam, M.B.6
  • 15
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-Term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study) randomised controlled trial
    • Keech A, Simes RJ, Barter P, Best J, Scott R, Taskinen MR, et al. Effects of long-Term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study) randomised controlled trial. Lancet 2005; 366: 1849-1861.
    • (2005) Lancet , vol.366 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, P.3    Best, J.4    Scott, R.5    Taskinen, M.R.6
  • 16
    • 0037049366 scopus 로고    scopus 로고
    • Diabetes, plasma insulin, and cardiovascular disease: Subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT
    • Rubins HB, Robins SJ, Collins D, Nelson DB, Elam MB, Schaefer EJ, et al. Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT). Arch Intern Med 2002; 162: 2597-2604.
    • (2002) Arch Intern Med , vol.162 , pp. 2597-2604
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3    Nelson, D.B.4    Elam, M.B.5    Schaefer, E.J.6
  • 17
    • 77954921239 scopus 로고    scopus 로고
    • Fibrates: No ACCORD on their use in the treatment of dyslipidaemia
    • Wierzbicki AS. Fibrates: no ACCORD on their use in the treatment of dyslipidaemia. Curr Opin Lipidol 2010; 21: 352-358.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 352-358
    • Wierzbicki, A.S.1
  • 18
    • 33645730513 scopus 로고    scopus 로고
    • Cardioprotective properties of fibrates: Which fibrate, which patients, what mechanism?
    • Barter PJ, Rye KA. Cardioprotective properties of fibrates: which fibrate, which patients, what mechanism?. Circulation 2006; 113: 1553-1555.
    • (2006) Circulation , vol.113 , pp. 1553-1555
    • Barter, P.J.1    Rye, K.A.2
  • 19
    • 84868286230 scopus 로고    scopus 로고
    • Variants identified in a GWAS meta-Analysis for blood lipids are associated with the lipid response to fenofibrate
    • Aslibekyan S, Goodarzi MO, Frazier-Wood AC, Yan X, Irvin MR, Kim E, et al. Variants identified in a GWAS meta-Analysis for blood lipids are associated with the lipid response to fenofibrate. PLoS ONE 2012; 7: e48663.
    • (2012) PLoS ONE , vol.7 , pp. e48663
    • Aslibekyan, S.1    Goodarzi, M.O.2    Frazier-Wood, A.C.3    Yan, X.4    Irvin, M.R.5    Kim, E.6
  • 20
    • 84862779585 scopus 로고    scopus 로고
    • Rare ppara variants and extreme response to fenofibrate in the genetics of lipid-lowering drugs and diet network study
    • Irvin MR, Zhang Q, Kabagambe EK, Perry RT, Straka RJ, Tiwari HK, et al. Rare PPARA variants and extreme response to fenofibrate in the Genetics of Lipid-Lowering Drugs and Diet Network Study. Pharmacogenet Genomics 2012; 22: 367-372.
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 367-372
    • Irvin, M.R.1    Zhang, Q.2    Kabagambe, E.K.3    Perry, R.T.4    Straka, R.J.5    Tiwari, H.K.6
  • 21
    • 78149332747 scopus 로고    scopus 로고
    • Apolipoprotein B genetic variants modify the response to fenofibrate: A GOLDN study
    • Wojczynski MK, Gao G, Borecki I, Hopkins PN, Parnell L, Lai CQ, et al. Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study. J Lipid Res 2010; 51: 3316-3323.
    • (2010) J Lipid Res , vol.51 , pp. 3316-3323
    • Wojczynski, M.K.1    Gao, G.2    Borecki, I.3    Hopkins, P.N.4    Parnell, L.5    Lai, C.Q.6
  • 22
    • 48649105226 scopus 로고    scopus 로고
    • Association of common C-reactive protein (CRP) gene polymorphisms with baseline plasma CRP levels and fenofibrate response: The GOLDN study
    • Shen J, Arnett DK, Parnell LD, Peacock JM, Lai CQ, Hixson JE, et al. Association of common C-reactive protein (CRP) gene polymorphisms with baseline plasma CRP levels and fenofibrate response: the GOLDN study. Diabetes Care 2008; 31: 910-915.
    • (2008) Diabetes Care , vol.31 , pp. 910-915
    • Shen, J.1    Arnett, D.K.2    Parnell, L.D.3    Peacock, J.M.4    Lai, C.Q.5    Hixson, J.E.6
  • 23
  • 24
    • 78649370520 scopus 로고    scopus 로고
    • Apolipoprotein e polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the genetics of lipid lowering and diet network (goldn) study
    • Irvin MR, Kabagambe EK, Tiwari HK, Parnell LD, Straka RJ, Tsai M, et al. Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the Genetics of Lipid Lowering and Diet Network (GOLDN) Study. Circ Cardiovasc Genet 2010; 3: 462-467.
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 462-467
    • Irvin, M.R.1    Kabagambe, E.K.2    Tiwari, H.K.3    Parnell, L.D.4    Straka, R.J.5    Tsai, M.6
  • 27
    • 48549097021 scopus 로고    scopus 로고
    • The SCARB1 gene is associated with lipid response to dietary and pharmacological interventions
    • Liu Y, Ordovas JM, Gao G, Province M, Straka RJ, Tsai MY, et al. The SCARB1 gene is associated with lipid response to dietary and pharmacological interventions. J Hum Genet 2008; 53: 709-717.
    • (2008) J Hum Genet , vol.53 , pp. 709-717
    • Liu, Y.1    Ordovas, J.M.2    Gao, G.3    Province, M.4    Straka, R.J.5    Tsai, M.Y.6
  • 28
    • 85027950257 scopus 로고    scopus 로고
    • A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network
    • Aslibekyan S, Kabagambe EK, Irvin MR, Straka RJ, Borecki IB, Tiwari HK, et al. A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network. Pharmacogenet Genomics 2012; 22: 191-197.
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 191-197
    • Aslibekyan, S.1    Kabagambe, E.K.2    Irvin, M.R.3    Straka, R.J.4    Borecki, I.B.5    Tiwari, H.K.6
  • 29
    • 84864417548 scopus 로고    scopus 로고
    • Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
    • Howie B, Fuchsberger C, Stephens M, Marchini J, Abecasis GR. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat Genet 2012; 44: 955-959.
    • (2012) Nat Genet , vol.44 , pp. 955-959
    • Howie, B.1    Fuchsberger, C.2    Stephens, M.3    Marchini, J.4    Abecasis, G.R.5
  • 31
    • 84856478855 scopus 로고    scopus 로고
    • A linear complexity phasing method for thousands of genomes
    • Delaneau O, Marchini J, Zagury JF. A linear complexity phasing method for thousands of genomes. Nat Methods 2012; 9: 179-181.
    • (2012) Nat Methods , vol.9 , pp. 179-181
    • Delaneau, O.1    Marchini, J.2    Zagury, J.F.3
  • 32
    • 84871952176 scopus 로고    scopus 로고
    • Improved whole-chromosome phasing for disease and population genetic studies
    • Delaneau O, Zagury JF, Marchini J. Improved whole-chromosome phasing for disease and population genetic studies. Nat Methods 2013; 10: 5-6.
    • (2013) Nat Methods , vol.10 , pp. 5-6
    • Delaneau, O.1    Zagury, J.F.2    Marchini, J.3
  • 33
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie BN, Donnelly P, Marchini J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet 2009; 5: e1000529.
    • (2009) PLoS Genet , vol.5 , pp. e1000529
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 34
  • 37
    • 38649132270 scopus 로고    scopus 로고
    • Six new loci associated with blood low-density lipoprotein cholesterol highdensity lipoprotein cholesterol or triglycerides in humans
    • Kathiresan S, Melander O, Guiducci C, Surti A, Burtt NP, Rieder MJ, et al. Six new loci associated with blood low-density lipoprotein cholesterol, highdensity lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008; 40: 189-197.
    • (2008) Nat Genet , vol.40 , pp. 189-197
    • Kathiresan, S.1    Melander, O.2    Guiducci, C.3    Surti, A.4    Burtt, N.P.5    Rieder, M.J.6
  • 39
    • 84871267657 scopus 로고    scopus 로고
    • Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population
    • Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, et al. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. PLoS One 2012; 7: e51954.
    • (2012) PLoS One , vol.7 , pp. e51954
    • Comuzzie, A.G.1    Cole, S.A.2    Laston, S.L.3    Voruganti, V.S.4    Haack, K.5    Gibbs, R.A.6
  • 40
    • 38649125868 scopus 로고    scopus 로고
    • Newly identified loci that influence lipid concentrations and risk of coronary artery disease
    • Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R, et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008; 40: 161-169.
    • (2008) Nat Genet , vol.40 , pp. 161-169
    • Willer, C.J.1    Sanna, S.2    Jackson, A.U.3    Scuteri, A.4    Bonnycastle, L.L.5    Clarke, R.6
  • 42
    • 58149161560 scopus 로고    scopus 로고
    • Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
    • Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2009; 41: 47-55.
    • (2009) Nat Genet , vol.41 , pp. 47-55
    • Aulchenko, Y.S.1    Ripatti, S.2    Lindqvist, I.3    Boomsma, D.4    Heid, I.M.5    Pramstaller, P.P.6
  • 43
    • 84898058547 scopus 로고    scopus 로고
    • Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk
    • Holmen OL, Zhang H, Fan Y, Hovelson DH, Schmidt EM, Zhou W, et al. Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. Nat Genet 2014; 46: 345-351.
    • (2014) Nat Genet , vol.46 , pp. 345-351
    • Holmen, O.L.1    Zhang, H.2    Fan, Y.3    Hovelson, D.H.4    Schmidt, E.M.5    Zhou, W.6
  • 46
    • 63449121037 scopus 로고    scopus 로고
    • Osteocrin - Beyond just another bone protein?
    • Moffatt P, Thomas GP. Osteocrin - beyond just another bone protein?. Cell Mol Life Sci 2009; 66: 1135-1139.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 1135-1139
    • Moffatt, P.1    Thomas, G.P.2


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