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Volumn 51, Issue 11, 2010, Pages 3316-3323

Apolipoprotein B genetic variants modify the response to fenofibrate: A GOLDN study

Author keywords

Fenofibrate; Genetics of lipid lowering drugs and diet network; Polymorphism; Triglycerides

Indexed keywords

APOLIPOPROTEIN B; FENOFIBRATE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 78149332747     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.P001834     Document Type: Article
Times cited : (30)

References (47)
  • 1
    • 33846637379 scopus 로고    scopus 로고
    • Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies
    • Sarwar, N., J. Danesh, G. Eiriksdottir, G. Sigurdsson, N. Wareham, S. Bingham, S. M. Boekholdt, K. T. Khaw, and V. Gudnason. 2007. Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation. 115: 450-458.
    • (2007) Circulation , vol.115 , pp. 450-458
    • Sarwar, N.1    Danesh, J.2    Eiriksdottir, G.3    Sigurdsson, G.4    Wareham, N.5    Bingham, S.6    Boekholdt, S.M.7    Khaw, K.T.8    Gudnason, V.9
  • 3
    • 13044304197 scopus 로고    scopus 로고
    • An overview of genetic factors influencing plasma lipid levels and coronary artery disease risk
    • Ozturk, I. C., and A. A. Killeen. 1999. An overview of genetic factors influencing plasma lipid levels and coronary artery disease risk. Arch. Pathol. Lab. Med. 123: 1219-1222.
    • (1999) Arch. Pathol. Lab. Med. , vol.123 , pp. 1219-1222
    • Ozturk, I.C.1    Killeen, A.A.2
  • 5
    • 63849198178 scopus 로고    scopus 로고
    • Hypertriglyceridemia and its pharmacologic treatment among US adults
    • Ford, E. S., C. Li, G. Zhao, W. S. Pearson, and A. H. Mokdad. 2009. Hypertriglyceridemia and its pharmacologic treatment among US adults. Arch. Intern. Med. 169: 572-578.
    • (2009) Arch. Intern. Med. , vol.169 , pp. 572-578
    • Ford, E.S.1    Li, C.2    Zhao, G.3    Pearson, W.S.4    Mokdad, A.H.5
  • 6
    • 33746038089 scopus 로고    scopus 로고
    • Fibric acid derivatives in cardiovascular disease prevention: Results from the large clinical trials
    • Robins, S. J., and H. E. Bloomfield. 2006. Fibric acid derivatives in cardiovascular disease prevention: results from the large clinical trials. Curr. Opin. Lipidol. 17: 431-439.
    • (2006) Curr. Opin. Lipidol. , vol.17 , pp. 431-439
    • Robins, S.J.1    Bloomfield, H.E.2
  • 7
    • 33846262603 scopus 로고    scopus 로고
    • Fenofibrate: A review of its use in primary dyslipidaemia, the metabolic syndrome and type 2 diabetes mellitus
    • Keating, G. M., and K. F. Croom. 2007. Fenofibrate: a review of its use in primary dyslipidaemia, the metabolic syndrome and type 2 diabetes mellitus. Drugs. 67: 121-153.
    • (2007) Drugs , vol.67 , pp. 121-153
    • Keating, G.M.1    Croom, K.F.2
  • 8
    • 0031473384 scopus 로고    scopus 로고
    • Association of apolipoprotein genetic polymorphisms with plasma cholesterol in a Japanese rural population. The Shibata Study
    • Zaman, M. M., S. Ikemoto, N. Yoshiike, C. Date, T. Yokoyama, and H. Tanaka. 1997. Association of apolipoprotein genetic polymorphisms with plasma cholesterol in a Japanese rural population. The Shibata Study. Arterioscler. Thromb. Vasc. Biol. 17: 3495-3504.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 3495-3504
    • Zaman, M.M.1    Ikemoto, S.2    Yoshiike, N.3    Date, C.4    Yokoyama, T.5    Tanaka, H.6
  • 10
    • 0028179072 scopus 로고
    • ApoB metabolism in familial hypercholesterolemia. Inconsistencies with the LDL receptor paradigm
    • Fisher, W. R., L. A. Zech, and P. W. Stacpoole. 1994. ApoB metabolism in familial hypercholesterolemia. Inconsistencies with the LDL receptor paradigm. Arterioscler. Thromb. 14: 501-510.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 501-510
    • Fisher, W.R.1    Zech, L.A.2    Stacpoole, P.W.3
  • 11
    • 0032861798 scopus 로고    scopus 로고
    • The assembly and secretion of apolipoprotein B-containing lipoproteins
    • Olofsson, S. O., L. Asp, and J. Boren. 1999. The assembly and secretion of apolipoprotein B-containing lipoproteins. Curr. Opin. Lipidol. 10: 341-346.
    • (1999) Curr. Opin. Lipidol. , vol.10 , pp. 341-346
    • Olofsson, S.O.1    Asp, L.2    Boren, J.3
  • 12
    • 49649122219 scopus 로고    scopus 로고
    • The many intersecting pathways underlying apolipoprotein B secretion and degradation
    • Brodsky, J. L., and E. A. Fisher. 2008. The many intersecting pathways underlying apolipoprotein B secretion and degradation. Trends Endocrinol. Metab. 19: 254-259.
    • (2008) Trends Endocrinol. Metab. , vol.19 , pp. 254-259
    • Brodsky, J.L.1    Fisher, E.A.2
  • 13
    • 0024205653 scopus 로고
    • Variation of apolipoprotein- B gene is associated with obesity, high blood cholesterol levels, and increased risk of coronary heart disease
    • Rajput-Williams, J., T. J. Knott, S. C. Wallis, P. Sweetnam, J. Yarnell, N. Cox, G. I. Bell, N. E. Miller, and J. Scott. 1988. Variation of apolipoprotein- B gene is associated with obesity, high blood cholesterol levels, and increased risk of coronary heart disease. Lancet. 2: 1442-1446.
    • (1988) Lancet , vol.2 , pp. 1442-1446
    • Rajput-Williams, J.1    Knott, T.J.2    Wallis, S.C.3    Sweetnam, P.4    Yarnell, J.5    Cox, N.6    Bell, G.I.7    Miller, N.E.8    Scott, J.9
  • 14
    • 0028107588 scopus 로고
    • Apolipoprotein polymorphisms fail to define risk of coronary artery disease. Results of a prospective, angiographically controlled study
    • Marshall, H. W., L. C. Morrison, L. L. Wu, J. L. Anderson, P. S. Corneli, D. M. Stauffer, A. Allen, L. A. Karagounis, and R. H. Ward. 1994. Apolipoprotein polymorphisms fail to define risk of coronary artery disease. Results of a prospective, angiographically controlled study. Circulation. 89: 567-577.
    • (1994) Circulation , vol.89 , pp. 567-577
    • Marshall, H.W.1    Morrison, L.C.2    Wu, L.L.3    Anderson, J.L.4    Corneli, P.S.5    Stauffer, D.M.6    Allen, A.7    Karagounis, L.A.8    Ward, R.H.9
  • 16
    • 0036918538 scopus 로고    scopus 로고
    • Regarding "Testing for population subdivision and association in four case-control studies" [2]
    • DOI 10.1086/344582
    • Pankow, J. S., M. A. Province, S. C. Hunt, and D. K. Arnett. 2002. Regarding "Testing for population subdivision and association in four case-control studies". Am. J. Hum. Genet. 71: 1478-1480. (Pubitemid 36015903)
    • (2002) American Journal of Human Genetics , vol.71 , Issue.6 , pp. 1478-1480
    • Pankow, J.S.1    Province, M.A.2    Hunt, S.C.3    Arnett, D.K.4
  • 17
    • 0033006003 scopus 로고    scopus 로고
    • Allelic discrimination using fluorogenic probes and the 5′ nuclease assay
    • Livak, K. J. 1999. Allelic discrimination using fluorogenic probes and the 5′ nuclease assay. Genet. Anal. 14: 143-149.
    • (1999) Genet. Anal. , vol.14 , pp. 143-149
    • Livak, K.J.1
  • 18
    • 1642536532 scopus 로고    scopus 로고
    • Further studies of the influence of apolipoprotein B alleles on glucose and lipid metabolism
    • Bentzen, J., P. Poulsen, A. Vaag, and M. Fenger. 2003. Further studies of the influence of apolipoprotein B alleles on glucose and lipid metabolism. Hum. Biol. 75: 687-703.
    • (2003) Hum. Biol. , vol.75 , pp. 687-703
    • Bentzen, J.1    Poulsen, P.2    Vaag, A.3    Fenger, M.4
  • 24
    • 34248662666 scopus 로고    scopus 로고
    • Use of a random coefficient regression (RCR) model to estimate growth parameters
    • Corbett, J., A. Kraja, I. B. Borecki, and M. A. Province. 2003. Use of a random coefficient regression (RCR) model to estimate growth parameters. BMC Genet. 4 (Suppl. 1): S5.
    • (2003) BMC Genet. , vol.4 , Issue.SUPPL. 1
    • Corbett, J.1    Kraja, A.2    Borecki, I.B.3    Province, M.A.4
  • 25
    • 0020333131 scopus 로고
    • Random-effects models for longitudinal data
    • Laird, N. M., and J. H. Ware. 1982. Random-effects models for longitudinal data. Biometrics. 38: 963-974.
    • (1982) Biometrics , vol.38 , pp. 963-974
    • Laird, N.M.1    Ware, J.H.2
  • 27
    • 0032251946 scopus 로고    scopus 로고
    • Using SAS PROC MIXED to fit multilevel models, hierarchical models, and individual growth models
    • Singer, J. D. 1998. Using SAS PROC MIXED to fit multilevel models, hierarchical models, and individual growth models. J. Educ. Behav. Stat. 24: 323-355.
    • (1998) J. Educ. Behav. Stat. , vol.24 , pp. 323-355
    • Singer, J.D.1
  • 28
    • 17144407867 scopus 로고    scopus 로고
    • Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study
    • Lai, C. Q., S. Demissie, L. A. Cupples, Y. Zhu, X. Adiconis, L. D. Parnell, D. Corella, and J. M. Ordovas. 2004. Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study. J. Lipid Res. 45: 2096-2105.
    • (2004) J. Lipid Res. , vol.45 , pp. 2096-2105
    • Lai, C.Q.1    Demissie, S.2    Cupples, L.A.3    Zhu, Y.4    Adiconis, X.5    Parnell, L.D.6    Corella, D.7    Ordovas, J.M.8
  • 29
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett, J. C., B. Fry, J. Maller, and M. J. Daly. 2005. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 21: 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 31
    • 0031035851 scopus 로고    scopus 로고
    • Polymorphisms of the genes encoding apoproteins A-I, B, C-III, and E and LDL receptor, and cholesterol and LDL metabolism during increased cholesterol intake. Common alleles of the apoprotein E gene show the greatest regulatory impact
    • Gylling, H., K. Kontula, U. M. Koivisto, H. E. Miettinen, and T. A. Miettinen. 1997. Polymorphisms of the genes encoding apoproteins A-I, B, C-III, and E and LDL receptor, and cholesterol and LDL metabolism during increased cholesterol intake. Common alleles of the apoprotein E gene show the greatest regulatory impact. Arterioscler. Thromb. Vasc. Biol. 17: 38-44.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 38-44
    • Gylling, H.1    Kontula, K.2    Koivisto, U.M.3    Miettinen, H.E.4    Miettinen, T.A.5
  • 32
    • 3442885746 scopus 로고    scopus 로고
    • Apolipoprotein B signal peptide polymorphism and plasma LDL-cholesterol response to low-calorie diet
    • Jemaa, R., A. Mebazaa, and F. Fumeron. 2004. Apolipoprotein B signal peptide polymorphism and plasma LDL-cholesterol response to low-calorie diet. Int. J. Obes. Relat. Metab. Disord. 28: 902-905.
    • (2004) Int. J. Obes. Relat. Metab. Disord. , vol.28 , pp. 902-905
    • Jemaa, R.1    Mebazaa, A.2    Fumeron, F.3
  • 33
    • 0020533327 scopus 로고
    • Effects of clofibrate, bezafibrate, fenofibrate and probucol on plasma lipolytic enzymes in normolipaemic subjects
    • Heller, F., and C. Harvengt. 1983. Effects of clofibrate, bezafibrate, fenofibrate and probucol on plasma lipolytic enzymes in normolipaemic subjects. Eur. J. Clin. Pharmacol. 25: 57-63.
    • (1983) Eur. J. Clin. Pharmacol. , vol.25 , pp. 57-63
    • Heller, F.1    Harvengt, C.2
  • 34
    • 0028817459 scopus 로고
    • Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates
    • Staels, B., N. Vu-Dac, V. A. Kosykh, R. Saladin, J. C. Fruchart, J. Dallongeville, and J. Auwerx. 1995. Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates. J. Clin. Invest. 95: 705-712.
    • (1995) J. Clin. Invest. , vol.95 , pp. 705-712
    • Staels, B.1    Vu-Dac, N.2    Kosykh, V.A.3    Saladin, R.4    Fruchart, J.C.5    Dallongeville, J.6    Auwerx, J.7
  • 36
    • 0029941224 scopus 로고    scopus 로고
    • Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalizes the atherogenic, dense LDL profile in combined hyperlipidemia
    • Guerin, M., E. Bruckert, P. J. Dolphin, G. Turpin, and M. J. Chapman. 1996. Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalizes the atherogenic, dense LDL profile in combined hyperlipidemia. Arterioscler. Thromb. Vasc. Biol. 16: 763-772.
    • (1996) Arterioscler. Thromb. Vasc. Biol. , vol.16 , pp. 763-772
    • Guerin, M.1    Bruckert, E.2    Dolphin, P.J.3    Turpin, G.4    Chapman, M.J.5
  • 37
    • 0043122919 scopus 로고    scopus 로고
    • SIFT: Predicting amino acid changes that affect protein function
    • Ng, P. C., and S. Henikoff. 2003. SIFT: predicting amino acid changes that affect protein function. Nucleic Acids Res. 31: 3812-3814.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3812-3814
    • Ng, P.C.1    Henikoff, S.2
  • 39
    • 0021798836 scopus 로고
    • Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver
    • Windler, E., and R. J. Havel. 1985. Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver. J. Lipid Res. 26: 556-565.
    • (1985) J. Lipid Res. , vol.26 , pp. 556-565
    • Windler, E.1    Havel, R.J.2
  • 40
    • 0021954138 scopus 로고
    • Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III
    • Wang, C. S., W. J. McConathy, H. U. Kloer, and P. Alaupovic. 1985. Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III. J. Clin. Invest. 75: 384-390.
    • (1985) J. Clin. Invest. , vol.75 , pp. 384-390
    • Wang, C.S.1    McConathy, W.J.2    Kloer, H.U.3    Alaupovic, P.4
  • 41
    • 0025940314 scopus 로고
    • Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein
    • Beisiegel, U., W. Weber, and G. Bengtsson-Olivecrona. 1991. Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein. Proc. Natl. Acad. Sci. USA. 88: 8342-8346.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8342-8346
    • Beisiegel, U.1    Weber, W.2    Bengtsson-Olivecrona, G.3
  • 43
    • 0037339775 scopus 로고    scopus 로고
    • Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome
    • Watts, G. F., P. H. Barrett, J. Ji, A. P. Serone, D. C. Chan, K. D. Croft, F. Loehrer, and A. G. Johnson. 2003. Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome. Diabetes. 52: 803-811.
    • (2003) Diabetes , vol.52 , pp. 803-811
    • Watts, G.F.1    Barrett, P.H.2    Ji, J.3    Serone, A.P.4    Chan, D.C.5    Croft, K.D.6    Loehrer, F.7    Johnson, A.G.8
  • 45
    • 20144388057 scopus 로고    scopus 로고
    • Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms and their association with carotid artery intima-media thickness in the Finnish population. The Cardiovascular Risk in Young Finns Study
    • Islam, M. S., O. T. Raitakari, M. Juonala, M. Kahonen, N. Hutri-Kahonen, A. Collings, K. Aalto-Setala, K. Kontula, J. Marniemi, J. S. Viikari, et al. 2005. Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms and their association with carotid artery intima-media thickness in the Finnish population. The Cardiovascular Risk in Young Finns Study. Atherosclerosis. 180: 79-86.
    • (2005) Atherosclerosis , vol.180 , pp. 79-86
    • Islam, M.S.1    Raitakari, O.T.2    Juonala, M.3    Kahonen, M.4    Hutri-Kahonen, N.5    Collings, A.6    Aalto-Setala, K.7    Kontula, K.8    Marniemi, J.9    Viikari, J.S.10
  • 47
    • 0035288666 scopus 로고    scopus 로고
    • Relationship of Xba1 and EcoR1 polymorphisms of apolipoprotein-B gene to dyslipidemia and obesity in Asian Indians in North India
    • Misra, A., S. Nishanth, S. T. Pasha, R. M. Pandey, P. Sethi, and D. S. Rawat. 2001. Relationship of Xba1 and EcoR1 polymorphisms of apolipoprotein-B gene to dyslipidemia and obesity in Asian Indians in North India. Indian Heart J. 53: 177-183.
    • (2001) Indian Heart J , vol.53 , pp. 177-183
    • Misra, A.1    Nishanth, S.2    Pasha, S.T.3    Pandey, R.M.4    Sethi, P.5    Rawat, D.S.6


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