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Volumn 171, Issue 1, 2003, Pages 1-13

Fibrates in 2003: Therapeutic action in atherogenic dyslipidaemia and future perspectives

Author keywords

Atherogenic lipoprotein phenotype; Atherosclerotic plaque; HDL; Metabolic syndrome; Peroxisome proliferator activated receptor ; Small dense LDL; Triglyceride rich lipoproteins; Type II diabetes

Indexed keywords

BEZAFIBRATE; CERIVASTATIN; CIPROFIBRATE; CLOFIBRATE; CYTOKINE; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MEVINOLIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SIMVASTATIN; TRIACYLGLYCEROL;

EID: 0344874601     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(03)00156-4     Document Type: Review
Times cited : (189)

References (94)
  • 1
    • 0035924611 scopus 로고    scopus 로고
    • The relative role of LDL-cholesterol and HDL-cholesterol in coronary artery disease: Evidence from large-scale statin and fibrate trials
    • Sacks F.M. The relative role of LDL-cholesterol and HDL-cholesterol in coronary artery disease: evidence from large-scale statin and fibrate trials. Am. J. Cardiol. 88:(Suppl.):2001;14N-18N.
    • (2001) Am. J. Cardiol. , vol.88 , Issue.SUPPL.
    • Sacks, F.M.1
  • 2
    • 58149212612 scopus 로고
    • Distribution of lipids in 8500 men with coronary artery disease
    • Rubins H.B., Robins S.J., Collins D., et al. Distribution of lipids in 8500 men with coronary artery disease. Am. J. Cardiol. 75:1995;1196-1201.
    • (1995) Am. J. Cardiol. , vol.75 , pp. 1196-1201
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 3
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of CAD in men with low levels of high-density lipoprotein cholesterol: Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
    • Rubins H.B., Robins S.J., Collins D., et al. Gemfibrozil for the secondary prevention of CAD in men with low levels of high-density lipoprotein cholesterol: Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. New Engl. J. Med. 341:1999;410-418.
    • (1999) New Engl. J. Med. , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 4
    • 0035924637 scopus 로고    scopus 로고
    • Targeting high-density lipoprotein cholesterol for therapy: Lessons from Veterans Affairs High-Density Lipoprotein Intervention Trial
    • Robins S.J. Targeting high-density lipoprotein cholesterol for therapy: lessons from Veterans Affairs High-Density Lipoprotein Intervention Trial. Am. J. Cardiol. 88:(Suppl.):2001;19N-23N.
    • (2001) Am. J. Cardiol. , vol.88 , Issue.SUPPL.
    • Robins, S.J.1
  • 5
    • 0023029454 scopus 로고
    • Incidence of CAD and lipoprotein cholesterol levels: The Framingham Study
    • Castelli W.P., Garrison R.J., Wilson P.W., et al. Incidence of CAD and lipoprotein cholesterol levels: the Framingham Study. J. Am. Med. Assoc. 256:1986;2835-2838.
    • (1986) J. Am. Med. Assoc. , vol.256 , pp. 2835-2838
    • Castelli, W.P.1    Garrison, R.J.2    Wilson, P.W.3
  • 6
    • 0024501678 scopus 로고
    • High density lipoprotein cholesterol and cardiovascular disease: Four prospective American studies
    • Gordon D.J., Probstfield J.L., Garrison R.J., et al. High density lipoprotein cholesterol and cardiovascular disease: four prospective American studies. Circulation. 79:1989;8-15.
    • (1989) Circulation , vol.79 , pp. 8-15
    • Gordon, D.J.1    Probstfield, J.L.2    Garrison, R.J.3
  • 7
    • 0024230807 scopus 로고
    • High density lipoprotein cholesterol and mortality. The Framingham Study
    • Wilson P.W.F., Abbott R.D., Castelli W.P. High density lipoprotein cholesterol and mortality. The Framingham Study. Arteriosclerosis. 8:1988;737-741.
    • (1988) Arteriosclerosis , vol.8 , pp. 737-741
    • Wilson, P.W.F.1    Abbott, R.D.2    Castelli, W.P.3
  • 8
    • 26744455053 scopus 로고    scopus 로고
    • High density lipoproteins: The anti-atherogenic fraction
    • P.J. Barter, & K.A. Rye. Harwood Academic Publisher
    • Barter P.J., Clay M.A., Rye K.A. High density lipoproteins: the anti-atherogenic fraction. Barter P.J., Rye K.A. Plasma lipids and their role in disease. 1999;85-108 Harwood Academic Publisher.
    • (1999) Plasma lipids and their role in disease , pp. 85-108
    • Barter, P.J.1    Clay, M.A.2    Rye, K.A.3
  • 9
    • 0012383209 scopus 로고    scopus 로고
    • Atherogenicity of low-density lipoproteins: Mechanisms
    • P.J. Barter, & K.A. Rye. Harwood Academic Publisher
    • Chapman M.J. Atherogenicity of low-density lipoproteins: mechanisms. Barter P.J., Rye K.A. Plasma lipids and their role in disease. 1999;69-84 Harwood Academic Publisher.
    • (1999) Plasma lipids and their role in disease , pp. 69-84
    • Chapman, M.J.1
  • 10
    • 0344376582 scopus 로고    scopus 로고
    • Epidemiological evidence linking plasma lipoprotein disorders to atherosclerosis and other diseases
    • P.J. Barter, & K.A. Rye. Harwood Academic Publisher
    • Genest J. Jr, Cohn J.S. Epidemiological evidence linking plasma lipoprotein disorders to atherosclerosis and other diseases. Barter P.J., Rye K.A. Plasma lipids and their role in disease. 1999;46-68 Harwood Academic Publisher.
    • (1999) Plasma lipids and their role in disease , pp. 46-68
    • Genest Jr., J.1    Cohn, J.S.2
  • 11
    • 0026762806 scopus 로고
    • Familial lipoprotein disorders in patients with premature coronary artery disease
    • Genest J. Jr, Martin-Munley S.S., McNamara J.R., et al. Familial lipoprotein disorders in patients with premature coronary artery disease. Circulation. 85:1992;2025-2033.
    • (1992) Circulation , vol.85 , pp. 2025-2033
    • Genest Jr., J.1    Martin-Munley, S.S.2    Mcnamara, J.R.3
  • 12
    • 0001786523 scopus 로고
    • Diabetes and atherosclerosis: Epidemiological considerations
    • B. Draznin, & R.H. Eckel. Amsterdam: Elsevier
    • Haffner S., Stern M.P., Rewers M. Diabetes and atherosclerosis: epidemiological considerations. Draznin B., Eckel R.H. Diabetes and atherosclerosis. 1993;229-254 Elsevier, Amsterdam.
    • (1993) Diabetes and atherosclerosis , pp. 229-254
    • Haffner, S.1    Stern, M.P.2    Rewers, M.3
  • 13
    • 0027406191 scopus 로고
    • Diabetes, other risk factors and 12-year cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial
    • Stamler J., Vaccaro O., Neaton J.D., Wentworth D. Diabetes, other risk factors and 12-year cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care. 16:1993;434-444.
    • (1993) Diabetes Care , vol.16 , pp. 434-444
    • Stamler, J.1    Vaccaro, O.2    Neaton, J.D.3    Wentworth, D.4
  • 14
    • 0026065576 scopus 로고
    • Plasma triglyceride and coronary artery disease
    • Austin M.A. Plasma triglyceride and coronary artery disease. Arterioscler. Thromb. 11:1991;2-14.
    • (1991) Arterioscler. Thromb. , vol.11 , pp. 2-14
    • Austin, M.A.1
  • 15
    • 0006619806 scopus 로고    scopus 로고
    • Diabetic dyslipidemia: Implications for vascular risk
    • D.J. Betteridge. London: Martin Dunitz
    • Betteridge D.J. Diabetic dyslipidemia: implications for vascular risk. Betteridge D.J. Lipids current prospectives. 1996;135-158 Martin Dunitz, London.
    • (1996) Lipids current prospectives , pp. 135-158
    • Betteridge, D.J.1
  • 16
    • 0034746490 scopus 로고    scopus 로고
    • Proatherogenic role of elevated cholesteryl ester transfer from HDL to VLDL1 and dense LDL in type 2 diabetes: Impact of the degree of triglyceridemia
    • Guerin M., Le Goff W., Lassel T., Van Tol A., Steiner G., Chapman J. Proatherogenic role of elevated cholesteryl ester transfer from HDL to VLDL1 and dense LDL in type 2 diabetes: impact of the degree of triglyceridemia. Arterioscler. Thromb. Vasc. Biol. 21:2001;282-288.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 282-288
    • Guerin, M.1    Le Goff, W.2    Lassel, T.3    Van Tol, A.4    Steiner, G.5    Chapman, J.6
  • 17
    • 0024223817 scopus 로고
    • The Prospective Cardiovascular Munster (PROCAM) Study: Prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and the relationship to CAD
    • Assmann G., Schulte H. The Prospective Cardiovascular Munster (PROCAM) Study: prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and the relationship to CAD. Am. Heart J. 116:1988;1713-1724.
    • (1988) Am. Heart J. , vol.116 , pp. 1713-1724
    • Assmann, G.1    Schulte, H.2
  • 18
    • 0023854212 scopus 로고
    • Serum lipids, lipoproteins and macrovascular disease in non-insulin dependent diabetics: A possible new approach to prevention
    • Seviour P.W., Teal T.K., Richmond W., Elkeles R.S. Serum lipids, lipoproteins and macrovascular disease in non-insulin dependent diabetics: a possible new approach to prevention. Diabetes Med. 5:1988;166-171.
    • (1988) Diabetes Med. , vol.5 , pp. 166-171
    • Seviour, P.W.1    Teal, T.K.2    Richmond, W.3    Elkeles, R.S.4
  • 20
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the Metabolic Syndrome among US adults. Findings from the Third National Health and Nutrition Examination Survey
    • Ford E.S., Giles W.H., Dietz W.H. Prevalence of the Metabolic Syndrome among US adults. Findings from the Third National Health and Nutrition Examination Survey. J. Am. Med. Assoc. 287:2002;356-359.
    • (2002) J. Am. Med. Assoc. , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 21
    • 0029299438 scopus 로고
    • The response to retention hypothesis of early atherogenesis
    • Williams K.J., Tabas I. The response to retention hypothesis of early atherogenesis. Arterioscler. Thromb. Vasc. Biol. 15:1995;551-561.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 551-561
    • Williams, K.J.1    Tabas, I.2
  • 22
    • 0030937821 scopus 로고    scopus 로고
    • The role of triglyceride-rich lipoprotein families in the progression of atherosclerotic lesions as determined by sequential coronary angiography from a controlled clinical trial
    • Alaupovic P., Mack W.J., Knight-Gibson C., Hodis H.N. The role of triglyceride-rich lipoprotein families in the progression of atherosclerotic lesions as determined by sequential coronary angiography from a controlled clinical trial. Arterioscler. Thromb. Vasc. Biol. 17:1997;715-722.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 715-722
    • Alaupovic, P.1    Mack, W.J.2    Knight-Gibson, C.3    Hodis, H.N.4
  • 23
    • 0032990452 scopus 로고    scopus 로고
    • Pathophysiology of triglyceride-rich lipoproteins in atherothrombosis: Cellular aspects
    • Gianturco S.H., Bradley W.A. Pathophysiology of triglyceride-rich lipoproteins in atherothrombosis: cellular aspects. Clin. Cardiol. 22:1999;II7-II14.
    • (1999) Clin. Cardiol. , vol.22
    • Gianturco, S.H.1    Bradley, W.A.2
  • 24
    • 0028172762 scopus 로고
    • Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
    • Rapp J.H., Lespine A., Hamilton R.L., et al. Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. Arterioscler. Thromb. 14:1994;1767-1774.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 1767-1774
    • Rapp, J.H.1    Lespine, A.2    Hamilton, R.L.3
  • 25
    • 0031983878 scopus 로고    scopus 로고
    • Echolucency of computerised ultrasound images of carotid atherosclerotic plaques are associated with increased levels of triglyceride-rich lipoproteins as well as increased plaque lipid content
    • Gronholdt M.L.M. Echolucency of computerised ultrasound images of carotid atherosclerotic plaques are associated with increased levels of triglyceride-rich lipoproteins as well as increased plaque lipid content. Circulation. 97:1998;34-40.
    • (1998) Circulation , vol.97 , pp. 34-40
    • Gronholdt, M.L.M.1
  • 26
    • 0028903142 scopus 로고
    • Selective retention of VLDL, IDL, and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo: Molecular size as a determinant of fractional loss from the intima-inner media
    • Nordestgaard B.G., Wooton R., Lewis B. Selective retention of VLDL, IDL, and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo: molecular size as a determinant of fractional loss from the intima-inner media. Arterioscler. Thromb. Vasc. Biol. 15:1995;534-542.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 534-542
    • Nordestgaard, B.G.1    Wooton, R.2    Lewis, B.3
  • 27
    • 0035109541 scopus 로고    scopus 로고
    • Preferential reduction of VLDL-1 particle number by Fenofibrate in type IIB hyperlipidemia: Consequences for uptake by human monocyte-derived macrophages
    • Milosavljevic D., Griglio S., Le Naour G., Chapman M.J. Preferential reduction of VLDL-1 particle number by Fenofibrate in type IIB hyperlipidemia: consequences for uptake by human monocyte-derived macrophages. Atherosclerosis. 155:(1):2001;251-260.
    • (2001) Atherosclerosis , vol.155 , Issue.1 , pp. 251-260
    • Milosavljevic, D.1    Griglio, S.2    Le Naour, G.3    Chapman, M.J.4
  • 28
    • 0031458498 scopus 로고
    • Lipoprotein heterogeneity and apolipoprotein B metabolism
    • Packard C.J., Shepherd J. Lipoprotein heterogeneity and apolipoprotein B metabolism. Arterioscler. Thromb. Vasc. Biol. 17:1977;3542-3556.
    • (1977) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 3542-3556
    • Packard, C.J.1    Shepherd, J.2
  • 29
    • 0027938951 scopus 로고
    • Heterogeneity of plasma low density lipoproteins and atherosclerosis risk
    • Krauss R.M. Heterogeneity of plasma low density lipoproteins and atherosclerosis risk. Curr. Opin. Lipidol. 5:1994;339-349.
    • (1994) Curr. Opin. Lipidol. , vol.5 , pp. 339-349
    • Krauss, R.M.1
  • 30
    • 0031890581 scopus 로고    scopus 로고
    • Atherogenic, dense LDL pathophysiology and new therapeutic approaches
    • Chapman M.J., Guerin M., Bruckert E. Atherogenic, dense LDL pathophysiology and new therapeutic approaches. Eur. Heart J. 19:1998;A24-A30.
    • (1998) Eur. Heart J. , vol.19
    • Chapman, M.J.1    Guerin, M.2    Bruckert, E.3
  • 31
    • 0022549920 scopus 로고
    • A receptor mediated pathway for cholesterol homeostasis
    • Brown M.S., Goldstein J.L. A receptor mediated pathway for cholesterol homeostasis. Science. 232:1986;34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 32
    • 0031472257 scopus 로고    scopus 로고
    • Interaction of very-low-density, intermediate-density and low-density lipoproteins with human arterial wall proteoglycans
    • Anber V., Millar J.S., McConnell M., Shepherd J., Packard C.J. Interaction of very-low-density, intermediate-density and low-density lipoproteins with human arterial wall proteoglycans. Arterioscler. Thromb. Vasc. Biol. 17:1997;2507-2514.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 2507-2514
    • Anber, V.1    Millar, J.S.2    Mcconnell, M.3    Shepherd, J.4    Packard, C.J.5
  • 33
    • 0028214532 scopus 로고
    • Why are low density lipoproteins atherogenic
    • Young S.G., Parthasarathy S. Why are low density lipoproteins atherogenic. West. J. Med. 160:1994;153-164.
    • (1994) West. J. Med. , vol.160 , pp. 153-164
    • Young, S.G.1    Parthasarathy, S.2
  • 34
    • 0028361107 scopus 로고
    • Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: Relative contribution of small dense LDL to CAD risk
    • Griffin B.A., Freeman D.J., Tait G.W., et al. Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: relative contribution of small dense LDL to CAD risk. Atherosclerosis. 106:1994;741-753.
    • (1994) Atherosclerosis , vol.106 , pp. 741-753
    • Griffin, B.A.1    Freeman, D.J.2    Tait, G.W.3
  • 35
    • 0031032723 scopus 로고    scopus 로고
    • Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from the Quebec Cardiovascular Study
    • Lamarche B., Tchernof A., Moorjani S., et al. Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from the Quebec Cardiovascular Study. Circulation. 95:1997;69-75.
    • (1997) Circulation , vol.95 , pp. 69-75
    • Lamarche, B.1    Tchernof, A.2    Moorjani, S.3
  • 36
    • 0035170229 scopus 로고    scopus 로고
    • High density lipoproteins and atherosclerosis. Role of cholesterol efflux and reverse cholesterol transport
    • Von Eckardstein A., Nofer J.R., Assmann G. High density lipoproteins and atherosclerosis. Role of cholesterol efflux and reverse cholesterol transport. Atheroscler. Thromb. Vasc. Biol. 21:2001;13-27.
    • (2001) Atheroscler. Thromb. Vasc. Biol. , vol.21 , pp. 13-27
    • Von Eckardstein, A.1    Nofer, J.R.2    Assmann, G.3
  • 37
    • 0032838901 scopus 로고    scopus 로고
    • HDL metabolism in hypertriglyceridemic states: An overview
    • Lamarche B., Rashid S., Lewis G.F. HDL metabolism in hypertriglyceridemic states: an overview. Clin. Chim. Acta. 286:1999;145-161.
    • (1999) Clin. Chim. Acta , vol.286 , pp. 145-161
    • Lamarche, B.1    Rashid, S.2    Lewis, G.F.3
  • 38
    • 0017614773 scopus 로고
    • High density lipoprotein and CAD: A prospective case-control study
    • Miller N.E., Thelle D.S., Forde O.H., Mjos O.D. High density lipoprotein and CAD: a prospective case-control study. Lancet. 1:1977;965-968.
    • (1977) Lancet , vol.1 , pp. 965-968
    • Miller, N.E.1    Thelle, D.S.2    Forde, O.H.3    Mjos, O.D.4
  • 39
    • 0018719409 scopus 로고
    • High density lipoprotein cholesterol and incidence of CAD - The Israeli Ischaemic Heart Disease Study
    • Goldbourt U., Medalie J.H. High density lipoprotein cholesterol and incidence of CAD - the Israeli Ischaemic Heart Disease Study. Am. J. Epidemiol. 109:1979;296-308.
    • (1979) Am. J. Epidemiol. , vol.109 , pp. 296-308
    • Goldbourt, U.1    Medalie, J.H.2
  • 40
    • 0025014653 scopus 로고
    • High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: The follow-up study of the Lipid Research Clinics Prevalence Study
    • Jacobs D.R., Mebane I.L., Bangdiwala S.I., Criqui M.H., Tyroler H.A. High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: the follow-up study of the Lipid Research Clinics Prevalence Study. Am. J. Epidemiol. 131:1990;32-47.
    • (1990) Am. J. Epidemiol. , vol.131 , pp. 32-47
    • Jacobs, D.R.1    Mebane, I.L.2    Bangdiwala, S.I.3    Criqui, M.H.4    Tyroler, H.A.5
  • 41
    • 0029759109 scopus 로고    scopus 로고
    • High density lipoprotein cholesterol as a predictor of CAD risk. The PROCAM experience and pathophysiological implications for reverse cholesterol transport
    • Assmann G., Schulte H., Von Eckardstein A., Huang Y. High density lipoprotein cholesterol as a predictor of CAD risk. The PROCAM experience and pathophysiological implications for reverse cholesterol transport. Atherosclerosis. 124:1996;S11-S20.
    • (1996) Atherosclerosis , vol.124
    • Assmann, G.1    Schulte, H.2    Von Eckardstein, A.3    Huang, Y.4
  • 42
    • 0033860421 scopus 로고    scopus 로고
    • How high-density lipoprotein protects against the effects of lipid peroxidation
    • Mackness M.I., Durrington P.N., Mackness B. How high-density lipoprotein protects against the effects of lipid peroxidation. Curr. Opin. Lipidol. 11:2000;383-388.
    • (2000) Curr. Opin. Lipidol. , vol.11 , pp. 383-388
    • Mackness, M.I.1    Durrington, P.N.2    Mackness, B.3
  • 43
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis E.J. Atherosclerosis. Nature. 407:2000;233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, E.J.1
  • 44
    • 0026656254 scopus 로고
    • Monocyte-endothelial cell interactions
    • Charo I.F. Monocyte-endothelial cell interactions. Curr. Opin. Lipidol. 3:1992;335-343.
    • (1992) Curr. Opin. Lipidol. , vol.3 , pp. 335-343
    • Charo, I.F.1
  • 45
    • 0020319988 scopus 로고
    • Stimulation of arterial endothelial cell prostacyclin synthesis by high density lipoproteins
    • Fleisher L.N., Tall A.R., Witte L.D., Muller R.W., Cannon P.J. Stimulation of arterial endothelial cell prostacyclin synthesis by high density lipoproteins. J. Biol. Chem. 257:1982;6653-6655.
    • (1982) J. Biol. Chem. , vol.257 , pp. 6653-6655
    • Fleisher, L.N.1    Tall, A.R.2    Witte, L.D.3    Muller, R.W.4    Cannon, P.J.5
  • 46
    • 0028227783 scopus 로고
    • Coronary atherosclerotic wall thickening and vascular reactivity in humans. Elevated high-density lipoprotein levels ameliorate abnormal vasoconstriction in early atherosclerosis
    • Zeiher A.M., Schachinger V., Hohnloser S.H. Coronary atherosclerotic wall thickening and vascular reactivity in humans. Elevated high-density lipoprotein levels ameliorate abnormal vasoconstriction in early atherosclerosis. Circulation. 89:1994;2525-2532.
    • (1994) Circulation , vol.89 , pp. 2525-2532
    • Zeiher, A.M.1    Schachinger, V.2    Hohnloser, S.H.3
  • 47
    • 0031595186 scopus 로고    scopus 로고
    • HDL3-mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositide-derived second messenger 1,2-diacylglycerol and inositol 1,4,5-tris-phosphate
    • Nofer J.R., Walter M., Kehrel B., et al. HDL3-mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositide-derived second messenger 1,2-diacylglycerol and inositol 1,4,5-tris-phosphate. Arterioscler. Thromb. Vasc. Biol. 18:1998;861-869.
    • (1998) Arterioscler. Thromb. Vasc. Biol. , vol.18 , pp. 861-869
    • Nofer, J.R.1    Walter, M.2    Kehrel, B.3
  • 48
    • 0031826009 scopus 로고    scopus 로고
    • Reconstituted high density lipoprotein (rHDL) modulates platelet activity in vitro and ex vivo
    • Lerch P.G., Spycher M.O., Doran J.E. Reconstituted high density lipoprotein (rHDL) modulates platelet activity in vitro and ex vivo. Thromb. Haemost. 80:1998;316-320.
    • (1998) Thromb. Haemost. , vol.80 , pp. 316-320
    • Lerch, P.G.1    Spycher, M.O.2    Doran, J.E.3
  • 50
    • 0033668998 scopus 로고    scopus 로고
    • Prevention of CAD by raising high-density lipoprotein cholesterol
    • Von Eckardstein A., Nofer J.R., Assmann G. Prevention of CAD by raising high-density lipoprotein cholesterol. Curr. Opin. Lipidol. 11:2000;627-637.
    • (2000) Curr. Opin. Lipidol. , vol.11 , pp. 627-637
    • Von Eckardstein, A.1    Nofer, J.R.2    Assmann, G.3
  • 51
    • 0028071959 scopus 로고
    • The effects of fibrates on lipoprotein and hemostatic coronary risk factors
    • Schonfeld G. The effects of fibrates on lipoprotein and hemostatic coronary risk factors. Atherosclerosis. 111:1994;161-174.
    • (1994) Atherosclerosis , vol.111 , pp. 161-174
    • Schonfeld, G.1
  • 52
    • 14344284525 scopus 로고    scopus 로고
    • Low high-density lipoprotein cholesterol as a risk factor in CAD. A Working Group Report
    • Gotto A.M. Low high-density lipoprotein cholesterol as a risk factor in CAD. A Working Group Report. Circulation. 103:2001;2213-2218.
    • (2001) Circulation , vol.103 , pp. 2213-2218
    • Gotto, A.M.1
  • 53
    • 0030690553 scopus 로고    scopus 로고
    • Micronised fenofibrate. A review of its pharmacodynamic properties and clinical efficacy in the management of dyslipidemia
    • Adkins J.C., Faulds D. Micronised fenofibrate. A review of its pharmacodynamic properties and clinical efficacy in the management of dyslipidemia. Drugs. 54:1997;615-633.
    • (1997) Drugs , vol.54 , pp. 615-633
    • Adkins, J.C.1    Faulds, D.2
  • 54
    • 0031968706 scopus 로고    scopus 로고
    • Effectiveness and tolerability of 12 week treatment with micronised fenofibrate 200 mg in a drug-monitoring programme involving 9884 patients with dyslipidemia
    • Kirschgassler K.U., Schmitz H., Bach G. Effectiveness and tolerability of 12 week treatment with micronised fenofibrate 200 mg in a drug-monitoring programme involving 9884 patients with dyslipidemia. Clin. Drug Invest. 15:1998;197-204.
    • (1998) Clin. Drug Invest. , vol.15 , pp. 197-204
    • Kirschgassler, K.U.1    Schmitz, H.2    Bach, G.3
  • 56
    • 0029941224 scopus 로고    scopus 로고
    • Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalises the atherogenic dense LDL profile in combined hyperlipidemia
    • Guerin M., Bruckert E., Dolphin P.J., Turpin G., Chapman M.J. Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalises the atherogenic dense LDL profile in combined hyperlipidemia. Arterioscler. Thromb. Vasc. Biol. 16:1996;763-772.
    • (1996) Arterioscler. Thromb. Vasc. Biol. , vol.16 , pp. 763-772
    • Guerin, M.1    Bruckert, E.2    Dolphin, P.J.3    Turpin, G.4    Chapman, M.J.5
  • 57
    • 0344808386 scopus 로고
    • Long term effect of ciprofibrate in patients with primary hyperlipidemia
    • Oro L., Carlsson L.A., Olsson A., Poole P.H. Long term effect of ciprofibrate in patients with primary hyperlipidemia. Curr. Ther. Res. 51:1992;229-243.
    • (1992) Curr. Ther. Res. , vol.51 , pp. 229-243
    • Oro, L.1    Carlsson, L.A.2    Olsson, A.3    Poole, P.H.4
  • 58
    • 0027285331 scopus 로고
    • Ciprofibrate therapy normalises the atherogenic low-density lipoprotein subspecies profile in combined hyperlipidemia
    • Bruckert E., Dejager S., Chapman M.J. Ciprofibrate therapy normalises the atherogenic low-density lipoprotein subspecies profile in combined hyperlipidemia. Atherosclerosis. 100:1993;91-102.
    • (1993) Atherosclerosis , vol.100 , pp. 91-102
    • Bruckert, E.1    Dejager, S.2    Chapman, M.J.3
  • 59
    • 0028017562 scopus 로고
    • Effects of ciprofibrate on LDL metabolism in man
    • Gaw A., Packard C.J., Caslake M.J., et al. Effects of ciprofibrate on LDL metabolism in man. Atherosclerosis. 108:1994;137-148.
    • (1994) Atherosclerosis , vol.108 , pp. 137-148
    • Gaw, A.1    Packard, C.J.2    Caslake, M.J.3
  • 60
    • 0030463802 scopus 로고    scopus 로고
    • Effects of simvastatin and ciprofibrate alone and in combination on lipid profile, plasma fibrinogen and LDL particle structure and distribution in patients with familial combined hyperlipidemia and coronary artery disease
    • Koutopoulos A.G., Athyros V.G., Papageorgiou A.A., Hatzikoustandinou H.A., Mayroudi M.C., Boudoulas H. Effects of simvastatin and ciprofibrate alone and in combination on lipid profile, plasma fibrinogen and LDL particle structure and distribution in patients with familial combined hyperlipidemia and coronary artery disease. Coronary Artery Dis. 7:1996;843-850.
    • (1996) Coronary Artery Dis. , vol.7 , pp. 843-850
    • Koutopoulos, A.G.1    Athyros, V.G.2    Papageorgiou, A.A.3    Hatzikoustandinou, H.A.4    Mayroudi, M.C.5    Boudoulas, H.6
  • 61
    • 0029758187 scopus 로고    scopus 로고
    • Efficacy and safety of ciprofibrate in hyperlipoproteinaemias
    • Turpin G., Bruckert E. Efficacy and safety of ciprofibrate in hyperlipoproteinaemias. Atherosclerosis. 124:(Suppl.):1996;S83-S87.
    • (1996) Atherosclerosis , vol.124 , Issue.SUPPL.
    • Turpin, G.1    Bruckert, E.2
  • 62
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary prevention trial with Gemfibrozil in middle-aged men with hyperlipidemia
    • Frick N.N., Elo O., Haapa K., et al. Helsinki Heart Study: primary prevention trial with Gemfibrozil in middle-aged men with hyperlipidemia. New Engl. J. Med. 317:1987;1237-1245.
    • (1987) New Engl. J. Med. , vol.317 , pp. 1237-1245
    • Frick, N.N.1    Elo, O.2    Haapa, K.3
  • 63
    • 0034604225 scopus 로고    scopus 로고
    • Secondary prevention by raising HDL-C and reducing triglycerides in patients with coronary artery disease. The Bezafibrate Infarction Prevention (BIP) Study
    • Secondary prevention by raising HDL-C and reducing triglycerides in patients with coronary artery disease. The Bezafibrate Infarction Prevention (BIP) Study. Circulation. 102:2000;21-27.
    • (2000) Circulation , vol.102 , pp. 21-27
  • 64
    • 0031922041 scopus 로고    scopus 로고
    • Cardiovascular outcome in type 2 diabetes. A double-blind placebo-controlled study of bezafibrate: The St Mary's, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention (SENDCAP) Study
    • Elkeles R.S., Diamond J.R., Poulter G., et al. Cardiovascular outcome in type 2 diabetes. A double-blind placebo-controlled study of bezafibrate: the St Mary's, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention (SENDCAP) Study. Diabetes Care. 21:1998;641-648.
    • (1998) Diabetes Care , vol.21 , pp. 641-648
    • Elkeles, R.S.1    Diamond, J.R.2    Poulter, G.3
  • 65
    • 0033376382 scopus 로고    scopus 로고
    • The impact of micronised fenofibrate on lipid subfractions and on reaching HDL target levels in 7098 patients with dyslipidemia
    • Poulter N. The impact of micronised fenofibrate on lipid subfractions and on reaching HDL target levels in 7098 patients with dyslipidemia. Br. J. Cardiol. 6:1999;682-685.
    • (1999) Br. J. Cardiol. , vol.6 , pp. 682-685
    • Poulter, N.1
  • 66
    • 0035941990 scopus 로고    scopus 로고
    • Effect of fenofibrate on progression of coronary artery disease in Type 2 diabetes: The Diabetes Atherosclerosis Intervention Study, a randomised study
    • Effect of fenofibrate on progression of coronary artery disease in Type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet. 357:2001;905-910.
    • (2001) Lancet , vol.357 , pp. 905-910
  • 67
    • 0033384110 scopus 로고    scopus 로고
    • Atherogenic lipoprotein phenotype in Type 2 diabetes: Reversal with micronised fenofibrate
    • Feher M.D., Caslake M., Foxton J., Cox A., Packard C.J. Atherogenic lipoprotein phenotype in Type 2 diabetes: reversal with micronised fenofibrate. Diabetes Metab. Res. Rev. 15:1999;395-399.
    • (1999) Diabetes Metab. Res. Rev. , vol.15 , pp. 395-399
    • Feher, M.D.1    Caslake, M.2    Foxton, J.3    Cox, A.4    Packard, C.J.5
  • 68
    • 0027225298 scopus 로고
    • Fenofibrate and low density lipoprotein metabolic heterogeneity in hypercholesterolemia
    • Caslake M.J., Packard C.J., Gaw A., et al. Fenofibrate and low density lipoprotein metabolic heterogeneity in hypercholesterolemia. Arterioscler. Thromb. 13:1993;702-711.
    • (1993) Arterioscler. Thromb. , vol.13 , pp. 702-711
    • Caslake, M.J.1    Packard, C.J.2    Gaw, A.3
  • 69
    • 0032076207 scopus 로고    scopus 로고
    • Effects of two different fibric derivatives on lipoproteins, cholesteryl ester transfer, fibrinogen, plasminogen activator inhibitor and paraoxonase activity in Type IIb-hyperlipoproteinemia
    • Durrington P.N., Mackness M.I., Bhatnagar D., et al. Effects of two different fibric derivatives on lipoproteins, cholesteryl ester transfer, fibrinogen, plasminogen activator inhibitor and paraoxonase activity in Type IIb-hyperlipoproteinemia. Atherosclerosis. 138:1998;217-225.
    • (1998) Atherosclerosis , vol.138 , pp. 217-225
    • Durrington, P.N.1    Mackness, M.I.2    Bhatnagar, D.3
  • 70
    • 0032506273 scopus 로고    scopus 로고
    • Mechanism of action of fibrates on lipid and lipoprotein metabolism
    • Staels B., Dallongeville J., Auwerx J., et al. Mechanism of action of fibrates on lipid and lipoprotein metabolism. Circulation. 98:1998;2088-2093.
    • (1998) Circulation , vol.98 , pp. 2088-2093
    • Staels, B.1    Dallongeville, J.2    Auwerx, J.3
  • 71
    • 0028292272 scopus 로고
    • Postprandial lipid metabolism
    • Cohn J.S. Postprandial lipid metabolism. Curr. Opin. Lipidol. 54:1994;185-190.
    • (1994) Curr. Opin. Lipidol. , vol.54 , pp. 185-190
    • Cohn, J.S.1
  • 72
    • 0028349617 scopus 로고
    • Postprandial lipoproteins and progression of coronary atherosclerosis
    • Karpe F., Steiner G., Uffelman K., et al. Postprandial lipoproteins and progression of coronary atherosclerosis. Atherosclerosis. 106:1993;83-97.
    • (1993) Atherosclerosis , vol.106 , pp. 83-97
    • Karpe, F.1    Steiner, G.2    Uffelman, K.3
  • 73
    • 17944401657 scopus 로고    scopus 로고
    • Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus
    • Evans M., Anderson R.A., Graham J., et al. Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus. Circulation. 101:2000;1773-1779.
    • (2000) Circulation , vol.101 , pp. 1773-1779
    • Evans, M.1    Anderson, R.A.2    Graham, J.3
  • 74
    • 0025651990 scopus 로고
    • Postprandial lipemia, fenofibrate and coronary artery disease
    • Simpson H.S., Williamson C.M., Olivecrona T., et al. Postprandial lipemia, fenofibrate and coronary artery disease. Atherosclerosis. 85:1990;193-202.
    • (1990) Atherosclerosis , vol.85 , pp. 193-202
    • Simpson, H.S.1    Williamson, C.M.2    Olivecrona, T.3
  • 75
    • 0033535977 scopus 로고    scopus 로고
    • Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease
    • Kugiyama K., Hideki D., Takazoe K., et al. Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease. Circulation. 99:1999;2858-2860.
    • (1999) Circulation , vol.99 , pp. 2858-2860
    • Kugiyama, K.1    Hideki, D.2    Takazoe, K.3
  • 76
    • 0033384740 scopus 로고    scopus 로고
    • Diabetic dyslipidemia and CAD: New perspectives
    • Evans M., Khan N., Rees A. Diabetic dyslipidemia and CAD: new perspectives. Curr. Opin. Lipidol. 10:1999;387-391.
    • (1999) Curr. Opin. Lipidol. , vol.10 , pp. 387-391
    • Evans, M.1    Khan, N.2    Rees, A.3
  • 77
    • 0029994543 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator activated receptor (PPAR) in mediating effects of fibrates and fatty acids on gene expression
    • Schoonjans K., Staels B., Auwerx J. Role of the peroxisome proliferator activated receptor (PPAR) in mediating effects of fibrates and fatty acids on gene expression. J. Lipid Res. 37:1996;907-925.
    • (1996) J. Lipid Res. , vol.37 , pp. 907-925
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 78
    • 0036094913 scopus 로고    scopus 로고
    • Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis
    • Barbier O., Pineda Torra I., Duguay Y., et al. Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 22:2002;717-726.
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 717-726
    • Barbier, O.1    Pineda Torra, I.2    Duguay, Y.3
  • 81
    • 0032565868 scopus 로고    scopus 로고
    • Activation of human aortic smooth muscle cells is inhibited by PPARα but not by PPARγ activators
    • Staels B., Koenig W., Habib A., et al. Activation of human aortic smooth muscle cells is inhibited by PPARα but not by PPARγ activators. Nature. 393:1998;790-793.
    • (1998) Nature , vol.393 , pp. 790-793
    • Staels, B.1    Koenig, W.2    Habib, A.3
  • 82
    • 0033594810 scopus 로고    scopus 로고
    • PPARα activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells
    • Marx M., Sukhova G.K., Collins T., Libby P., Plutzky J. PPARα activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation. 99:1999;3125-3131.
    • (1999) Circulation , vol.99 , pp. 3125-3131
    • Marx, M.1    Sukhova, G.K.2    Collins, T.3    Libby, P.4    Plutzky, J.5
  • 83
    • 0027232397 scopus 로고
    • The hemostatic system and CAD
    • Hamsten A. The hemostatic system and CAD. Thromb. Res. 70:1993;1-38.
    • (1993) Thromb. Res. , vol.70 , pp. 1-38
    • Hamsten, A.1
  • 84
    • 0030070847 scopus 로고    scopus 로고
    • Association between serum fibrinogen concentrations and HDL and LDL subfraction phenotypes in healthy men
    • Halle H., Berg A., Keul J., Baumstark M.W. Association between serum fibrinogen concentrations and HDL and LDL subfraction phenotypes in healthy men. Arterioscler. Thromb. Vasc. Biol. 16:1996;144-148.
    • (1996) Arterioscler. Thromb. Vasc. Biol. , vol.16 , pp. 144-148
    • Halle, H.1    Berg, A.2    Keul, J.3    Baumstark, M.W.4
  • 85
    • 0022180444 scopus 로고
    • Effect of ciprofibrate on platelet aggregation and fibrinolysis in patients with hypercholesterolaemia
    • Simpson I.A., Lorimer A.R., Walker I.D., Davidson J.F. Effect of ciprofibrate on platelet aggregation and fibrinolysis in patients with hypercholesterolaemia. Thromb. Haemostat. 54:1989;442-444.
    • (1989) Thromb. Haemostat. , vol.54 , pp. 442-444
    • Simpson, I.A.1    Lorimer, A.R.2    Walker, I.D.3    Davidson, J.F.4
  • 86
    • 0026597808 scopus 로고
    • Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on CAD risk in the Helsinki Heart Study. Implications for treatment
    • Manninen V., Tenkanen L., Koskinen P., et al. Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on CAD risk in the Helsinki Heart Study. Implications for treatment. Circulation. 85:1992;37-45.
    • (1992) Circulation , vol.85 , pp. 37-45
    • Manninen, V.1    Tenkanen, L.2    Koskinen, P.3
  • 87
    • 0029982038 scopus 로고    scopus 로고
    • Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients
    • Ericsson C.G., Hamsten A., Nilsson J., Grip L., Svane B., de Faire U. Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients. Lancet. 347:1996;849-853.
    • (1996) Lancet , vol.347 , pp. 849-853
    • Ericsson, C.G.1    Hamsten, A.2    Nilsson, J.3    Grip, L.4    Svane, B.5    De Faire, U.6
  • 88
    • 0342506477 scopus 로고    scopus 로고
    • Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol
    • Frick M.H., Syvanne M., Nieminen M.S., et al. Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol. Circulation. 96:1997;2137-2143.
    • (1997) Circulation , vol.96 , pp. 2137-2143
    • Frick, M.H.1    Syvanne, M.2    Nieminen, M.S.3
  • 89
    • 0032054839 scopus 로고    scopus 로고
    • Consensus for the use of fibrates in the treatment of dyslipoproteinemia and CAD
    • Fruchart J.C., Brewer H.B., Leitersdorf E. Consensus for the use of fibrates in the treatment of dyslipoproteinemia and CAD. Am. J. Cardiol. 81:1998;912-917.
    • (1998) Am. J. Cardiol. , vol.81 , pp. 912-917
    • Fruchart, J.C.1    Brewer, H.B.2    Leitersdorf, E.3
  • 90
    • 0035021878 scopus 로고    scopus 로고
    • Effect of intensive lipid-lowering strategy on low-density lipoprotein particle size in patients with Type 2 diabetes mellitus
    • Neimeijer S.D.J.M., Dallinga-Thie G.M., de Ruijter-Heijstek, et al. Effect of intensive lipid-lowering strategy on low-density lipoprotein particle size in patients with Type 2 diabetes mellitus. Atherosclerosis. 156:2001;209-216.
    • (2001) Atherosclerosis , vol.156 , pp. 209-216
    • Neimeijer, S.D.J.M.1    Dallinga-Thie, G.M.2    De Ruijter-Heijstek3
  • 92
    • 0033586641 scopus 로고    scopus 로고
    • Evidence for a new pathophysiological mechanism for coronary artery disease regression - Hepatic lipase mediated changes in LDL density
    • Zambon A., Hokanson J.E., Brown B.G., Brunzell J.D. Evidence for a new pathophysiological mechanism for coronary artery disease regression - hepatic lipase mediated changes in LDL density. Circulation. 99:1999;1959-1964.
    • (1999) Circulation , vol.99 , pp. 1959-1964
    • Zambon, A.1    Hokanson, J.E.2    Brown, B.G.3    Brunzell, J.D.4
  • 93
    • 0027183606 scopus 로고
    • Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles
    • Reaven J, GM, Chen YD, Jeppesen J, Maheux P, Krauss RM. Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles, J Clin Invest 1993;92:141-6.
    • (1993) J Clin Invest , vol.92 , pp. 141-146
    • Reaven, J.G.M.1    Chen, Y.D.2    Jeppesen, J.3    Maheux, P.4    Krauss, R.M.5
  • 94
    • 0034595980 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity
    • Guerre-Millo M., Gervois P., Raspé E., et al. Peroxisome- proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity. J. Biol. Chem. 275:2000;16638-16642.
    • (2000) J. Biol. Chem. , vol.275 , pp. 16638-16642
    • Guerre-Millo, M.1    Gervois, P.2    Raspé, E.3


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