TCRβ repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition

Journal of Leukocyte Biology

Volumn 99, Issue 3, 2016, Pages 505-513

  Li, Hoi Ming ^a   Hiroi, Toyoko ^a   Zhang, Yongqing ^a   Shi, Alvin ^a,c   Chen, Guobing ^a   De, Supriyo ^a   Jeffrey Metter, E ^a   Wood, William H ^a   Sharov, Alexei ^a   Milner, Joshua D ^b   Becker, Kevin G ^a   Zhan, Ming ^b   Weng, Nan Ping ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Human; RACE; RNAseq; Supervised learning; TCR diversity

Indexed keywords

ARGININE; ASPARAGINE; ASPARTIC ACID; COMPLEMENTARY DNA; CYSTEINE; ISOLEUCINE; LEUCINE; LYSINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROLINE; T LYMPHOCYTE RECEPTOR BETA CHAIN; THREONINE; VALINE; AMINO ACID; COMPLEMENTARITY DETERMINING REGION; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AGED; AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; COMPLEMENTARITY DETERMINING REGION; GENE SEQUENCE; HUMAN; HUMAN CELL; NEXT GENERATION SEQUENCING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SUPPORT VECTOR MACHINE; ANALYSIS; CHEMISTRY; IMMUNOLOGY; MIDDLE AGED; T LYMPHOCYTE RECEPTOR GENE;

ADULT; AGED; AMINO ACIDS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; COMPLEMENTARITY DETERMINING REGIONS; GENES, T-CELL RECEPTOR BETA; HUMANS; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 84961254556     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.6A0215-071RR     Document Type: Article

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