Age-Related decrease in TCR repertoire diversity measured with deep and normalized sequence profiling

Journal of Immunology

Volumn 192, Issue 6, 2014, Pages 2689-2698

  Britanova, Olga V ^a   Putintseva, Ekaterina V ^a   Shugay, Mikhail ^a,b   Merzlyak, Ekaterina M ^a   Turchaninova, Maria A ^a   Staroverov, Dmitriy B ^a   Bolotin, Dmitriy A ^a   Lukyanov, Sergey ^a,b   Bogdanova, Ekaterina A ^a   Mamedov, Ilgar Z ^a   Lebedev, Yuriy B ^a   Chudakov, Dmitriy M ^c  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^b PIROGOV RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY   (Russian Federation)

^c MASARYK UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ACCURACY; ADULT; AGE; AGE DISTRIBUTION; AGED; AGING; ARTICLE; BIOINFORMATICS; CD4+ T LYMPHOCYTE; CELL CLONING; CELL EXPANSION; CHILD; CONTROLLED STUDY; DNA BARCODING; FEMALE; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; MALE; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN DETERMINATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; AMINO ACID SEQUENCE; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CHILD; COMPLEMENTARITY DETERMINING REGIONS; FEMALE; FLOW CYTOMETRY; GENETIC VARIATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84897530472     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302064     Document Type: Article

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