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Volumn 369, Issue 1645, 2014, Pages

The application of transcriptional blood signatures to enhance our understanding of the host response to infection: The example of tuberculosis

Author keywords

Immune response; Infection; Tuberculosis

Indexed keywords

IMMUNE RESPONSE; MORBIDITY; MORTALITY; PUBLIC HEALTH; TUBERCULOSIS; VACCINATION;

EID: 84961146311     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2013.0427     Document Type: Article
Times cited : (66)

References (77)
  • 1
    • 77952318708 scopus 로고    scopus 로고
    • A genomic approach to human autoimmune diseases
    • (doi:10.1146/ annurev-immunol-030409-101221)
    • Pascual V, Chaussabel D, Banchereau J. 2010 A genomic approach to human autoimmune diseases. Annu. Rev. Immunol. 28, 535-571. (doi:10.1146/ annurev-immunol-030409-101221)
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 535-571
    • Pascual, V.1    Chaussabel, D.2    Banchereau, J.3
  • 2
    • 77954384233 scopus 로고    scopus 로고
    • Assessing the human immune system through blood transcriptomics
    • (doi:10. 1186/1741-7007-8-84)
    • Chaussabel D, Pascual V, Banchereau J. 2010 Assessing the human immune system through blood transcriptomics. BMC Biol. 8, 84. (doi:10. 1186/1741-7007-8-84)
    • (2010) BMC Biol. , vol.8 , pp. 84
    • Chaussabel, D.1    Pascual, V.2    Banchereau, J.3
  • 3
    • 84889672787 scopus 로고    scopus 로고
    • Transcriptional profiling in infectious diseases: Ready for prime time?
    • (doi:10.1016/j.jinf.2013.09.018)
    • Mejias A, Ramilo O. 2013 Transcriptional profiling in infectious diseases: ready for prime time? J. Infect. 68, S94-S99. (doi:10.1016/j.jinf.2013.09.018)
    • (2013) J. Infect. , vol.68
    • Mejias, A.1    Ramilo, O.2
  • 4
    • 84861123691 scopus 로고    scopus 로고
    • Ten years of pathway analysis: Current approaches and outstanding challenges
    • (doi:10.1371/journal.pcbi.1002375)
    • Khatri P, Sirota M, Butte AJ. 2012 Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput. Biol. 8, e1002375. (doi:10.1371/journal.pcbi.1002375)
    • (2012) PLoS Comput. Biol. , vol.8
    • Khatri, P.1    Sirota, M.2    Butte, A.J.3
  • 5
    • 79953050420 scopus 로고    scopus 로고
    • Systems biology in immunology: A computational modeling perspective
    • (doi:10.1146/annurevimmunol-030409-101317)
    • Germain RN, Meier-Schellersheim M, Nita-Lazar A, Fraser ID. 2011 Systems biology in immunology: a computational modeling perspective. Annu. Rev. Immunol. 29, 527-585. (doi:10.1146/annurevimmunol-030409-101317)
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 527-585
    • Germain, R.N.1    Meier-Schellersheim, M.2    Nita-Lazar, A.3    Fraser, I.D.4
  • 6
    • 58049203835 scopus 로고    scopus 로고
    • Systems biology of innate immunity
    • (doi:10. 1111/j.1600-065X.2008.00721.x)
    • Zak DE, Aderem A. 2009 Systems biology of innate immunity. Immunol. Rev. 227, 264-282. (doi:10. 1111/j.1600-065X.2008.00721.x)
    • (2009) Immunol. Rev. , vol.227 , pp. 264-282
    • Zak, D.E.1    Aderem, A.2
  • 7
    • 0036899286 scopus 로고    scopus 로고
    • From patterns to pathways: Gene expression data analysis comes of age
    • (doi:10.1038/ng1033)
    • Slonim DK. 2002 From patterns to pathways: gene expression data analysis comes of age. Nat. Genet. 32, 502-508. (doi:10.1038/ng1033)
    • (2002) Nat. Genet. , vol.32 , pp. 502-508
    • Slonim, D.K.1
  • 8
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • (doi:10.1126/science.286.5439.531)
    • Golub TR et al. 1999 Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286, 531-537. (doi:10.1126/science.286.5439.531)
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1
  • 9
    • 84876745847 scopus 로고    scopus 로고
    • Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines
    • (doi:10.1016/j.immuni.2012.12.008)
    • Obermoser G et al. 2013 Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines. Immunity 38, 831-844. (doi:10.1016/j.immuni.2012.12.008)
    • (2013) Immunity , vol.38 , pp. 831-844
    • Obermoser, G.1
  • 11
    • 35248840944 scopus 로고    scopus 로고
    • The peripheral-blood transcriptome: New insights into disease and risk assessment
    • (doi:10.1016/j.molmed.2007.08.003)
    • Mohr S, Liew CC. 2007 The peripheral-blood transcriptome: new insights into disease and risk assessment. Trends Mol. Med. 13, 422-432. (doi:10.1016/j.molmed.2007.08.003)
    • (2007) Trends Mol. Med. , vol.13 , pp. 422-432
    • Mohr, S.1    Liew, C.C.2
  • 12
    • 0016858724 scopus 로고
    • Letter: Racial differences in leucoyte count
    • (doi:10.1136/bmj.2.5972.684-c)
    • Rougemont A, Boisson ME. 1975 Letter: racial differences in leucoyte count. Br. Med. J. 2, 684-685. (doi:10.1136/bmj.2.5972.684-c)
    • (1975) Br. Med. J. , vol.2 , pp. 684-685
    • Rougemont, A.1    Boisson, M.E.2
  • 14
    • 84881086889 scopus 로고    scopus 로고
    • Gene expression profiles in febrile children with defined viral and bacterial infection
    • (doi:10.1073/pnas. 1302968110)
    • Hu X, Yu J, Crosby SD, Storch GA. 2013 Gene expression profiles in febrile children with defined viral and bacterial infection. Proc. Natl Acad. Sci. USA 110, 12 792-12 797. (doi:10.1073/pnas. 1302968110)
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 12792-12797
    • Hu, X.1    Yu, J.2    Crosby, S.D.3    Storch, G.A.4
  • 15
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • (doi:10. 1038/nature09247)
    • Berry MP et al. 2010 An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466, 973-977. (doi:10. 1038/nature09247)
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.1
  • 16
    • 84881104975 scopus 로고    scopus 로고
    • Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers
    • (doi:10.1371/journal. pone.0070630)
    • Bloom CI et al. 2013 Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers. PLoS ONE 8, e70630. (doi:10.1371/journal. pone.0070630)
    • (2013) PLoS ONE , vol.8
    • Bloom, C.I.1
  • 17
    • 84866686896 scopus 로고    scopus 로고
    • Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis
    • (doi:10.1371/journal.pone. 0045839)
    • Ottenhoff TH et al. 2012 Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis. PLoS ONE 7, e45839. (doi:10.1371/journal.pone. 0045839)
    • (2012) PLoS ONE , vol.7
    • Ottenhoff, T.H.1
  • 18
    • 80053414769 scopus 로고    scopus 로고
    • + T cells predicts prognosis in patients with Crohn disease and ulcerative colitis
    • (doi:10.1172/JCI59255)
    • + T cells predicts prognosis in patients with Crohn disease and ulcerative colitis. J. Clin. Invest. 121, 4170-4179. (doi:10.1172/JCI59255)
    • (2011) J. Clin. Invest. , vol.121 , pp. 4170-4179
    • Lee, J.C.1
  • 19
    • 80051989398 scopus 로고    scopus 로고
    • Systems biology of vaccination for seasonal influenza in humans
    • (doi:10.1038/ni.2067)
    • Nakaya HI et al. 2011 Systems biology of vaccination for seasonal influenza in humans. Nat. Immunol. 12, 786-795. (doi:10.1038/ni.2067)
    • (2011) Nat. Immunol. , vol.12 , pp. 786-795
    • Nakaya, H.I.1
  • 20
    • 84898018919 scopus 로고    scopus 로고
    • Computational deconvolution: Extracting cell type-specific information from heterogeneous samples
    • (doi:10.1016/j.coi. 2013.09.015)
    • Shen-Orr SS, Gaujoux R. 2013 Computational deconvolution: extracting cell type-specific information from heterogeneous samples. Curr. Opin. Immunol. 25, 571-578. (doi:10.1016/j.coi. 2013.09.015)
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 571-578
    • Shen-Orr, S.S.1    Gaujoux, R.2
  • 21
    • 70349443224 scopus 로고    scopus 로고
    • Transcriptional control of the inflammatory response
    • (doi:10.1038/nri2634)
    • Medzhitov R, Horng T. 2009 Transcriptional control of the inflammatory response. Nat. Rev. Immunol. 9, 692-703. (doi:10.1038/nri2634)
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 692-703
    • Medzhitov, R.1    Horng, T.2
  • 23
    • 46749152178 scopus 로고    scopus 로고
    • A modular analysis framework for blood genomics studies: Application to systemic lupus erythematosus
    • (doi:10.1016/j.immuni.2008.05.012)
    • Chaussabel D et al. 2008 A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity 29, 150-164. (doi:10.1016/j.immuni.2008.05.012)
    • (2008) Immunity , vol.29 , pp. 150-164
    • Chaussabel, D.1
  • 24
    • 76249091272 scopus 로고    scopus 로고
    • Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis
    • (doi:10.1186/ gb-2009-10-11-r127)
    • Pankla R, Buddhisa S, Berry M, Blankenship DM, Bancroft GJ, Banchereau J, Lertmemongkolchai G, Chaussabel D. 2009 Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis. Genome Biol. 10, R127. (doi:10.1186/ gb-2009-10-11-r127)
    • (2009) Genome Biol. , vol.10
    • Pankla, R.1    Buddhisa, S.2    Berry, M.3    Blankenship, D.M.4    Bancroft, G.J.5    Banchereau, J.6    Lertmemongkolchai, G.7    Chaussabel, D.8
  • 25
    • 84867031010 scopus 로고    scopus 로고
    • Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy
    • (doi:10.1371/journal.pone.0046191)
    • Bloom CI et al. 2012 Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy. PLoS ONE 7, e46191. (doi:10.1371/journal.pone.0046191)
    • (2012) PLoS ONE , vol.7
    • Bloom, C.I.1
  • 26
    • 33745484802 scopus 로고    scopus 로고
    • Analysis of significance patterns identifies ubiquitous and disease-specific geneexpression signatures in patient peripheral blood leukocytes
    • (doi:10.1196/annals.1358.017)
    • Chaussabel D, Allman W, Mejias A, Chung W, Bennett L, Ramilo O, Pascual V, Palucka AK, Banchereau J. 2005 Analysis of significance patterns identifies ubiquitous and disease-specific geneexpression signatures in patient peripheral blood leukocytes. Ann. NY Acad. Sci. 1062, 146-154. (doi:10.1196/annals.1358.017)
    • (2005) Ann. NY Acad. Sci. , vol.1062 , pp. 146-154
    • Chaussabel, D.1    Allman, W.2    Mejias, A.3    Chung, W.4    Bennett, L.5    Ramilo, O.6    Pascual, V.7    Palucka, A.K.8    Banchereau, J.9
  • 27
    • 33847408050 scopus 로고    scopus 로고
    • Gene expression patterns in blood leukocytes discriminate patients with acute infections
    • (doi:10.1182/ blood-2006-02-002477)
    • Ramilo O et al. 2007 Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood 109, 2066-2077. (doi:10.1182/ blood-2006-02-002477)
    • (2007) Blood , vol.109 , pp. 2066-2077
    • Ramilo, O.1
  • 28
    • 85027203102 scopus 로고    scopus 로고
    • Peripheral blood RNA gene expression profiling in patients with bacterial meningitis
    • (doi:10.3389/ fnins.2013.00033)
    • Lill M, Koks S, Soomets U, Schalkwyk LC, Fernandes C, Lutsar I, Taba P. 2013 Peripheral blood RNA gene expression profiling in patients with bacterial meningitis. Front. Neurosci. 7, 33. (doi:10.3389/ fnins.2013.00033)
    • (2013) Front. Neurosci. , vol.7 , pp. 33
    • Lill, M.1    Koks, S.2    Soomets, U.3    Schalkwyk, L.C.4    Fernandes, C.5    Lutsar, I.6    Taba, P.7
  • 29
    • 69149103242 scopus 로고    scopus 로고
    • Gene transcript abundance profiles distinguish Kawasaki disease from adenovirus infection
    • (doi:10.1086/603538)
    • Popper SJ, Watson VE, Shimizu C, Kanegaye JT, Burns JC, Relman DA. 2009 Gene transcript abundance profiles distinguish Kawasaki disease from adenovirus infection. J. Infect. Dis. 200, 657-666. (doi:10.1086/603538)
    • (2009) J. Infect. Dis. , vol.200 , pp. 657-666
    • Popper, S.J.1    Watson, V.E.2    Shimizu, C.3    Kanegaye, J.T.4    Burns, J.C.5    Relman, D.A.6
  • 30
    • 69949148793 scopus 로고    scopus 로고
    • Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans
    • (doi:10.1016/j.chom.2009. 07.006)
    • Zaas AK et al. 2009 Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. Cell Host Microbe 6, 207-217. (doi:10.1016/j.chom.2009. 07.006)
    • (2009) Cell Host Microbe , vol.6 , pp. 207-217
    • Zaas, A.K.1
  • 31
    • 84888990746 scopus 로고    scopus 로고
    • Whole blood gene expression profiles to assess pathogenesis and disease severity in infants with respiratory syncytial virus infection
    • (doi:10.1371/journal. pmed.1001549)
    • Mejias A et al. 2013 Whole blood gene expression profiles to assess pathogenesis and disease severity in infants with respiratory syncytial virus infection. PLoS Med. 10, e1001549. (doi:10.1371/journal. pmed.1001549)
    • (2013) PLoS Med. , vol.10
    • Mejias, A.1
  • 33
    • 44049104994 scopus 로고    scopus 로고
    • Differences in global gene expression in peripheral blood mononuclear cells indicate a significant role of the innate responses in progression of dengue fever but not dengue hemorrhagic fever
    • (doi:10.1086/587699)
    • Ubol S, Masrinoul P, Chaijaruwanich J, Kalayanarooj S, Charoensirisuthikul T, Kasisith J. 2008 Differences in global gene expression in peripheral blood mononuclear cells indicate a significant role of the innate responses in progression of dengue fever but not dengue hemorrhagic fever. J. Infect. Dis. 197, 1459-1467. (doi:10.1086/587699)
    • (2008) J. Infect. Dis. , vol.197 , pp. 1459-1467
    • Ubol, S.1    Masrinoul, P.2    Chaijaruwanich, J.3    Kalayanarooj, S.4    Charoensirisuthikul, T.5    Kasisith, J.6
  • 34
    • 70949100884 scopus 로고    scopus 로고
    • Gene expression profiling during early acute febrile stage of dengue infection can predict the disease outcome
    • (doi:10.1371/journal.pone. 0007892)
    • Nascimento EJ et al. 2009 Gene expression profiling during early acute febrile stage of dengue infection can predict the disease outcome. PLoS ONE 4, e7892. (doi:10.1371/journal.pone. 0007892)
    • (2009) PLoS ONE , vol.4
    • Nascimento, E.J.1
  • 35
    • 77956995857 scopus 로고    scopus 로고
    • Gene expression patterns of dengue virus-infected children from Nicaragua reveal a distinct signature of increased metabolism
    • (doi:10.1371/journal. pntd.0000710)
    • Loke P, Hammond SN, Leung JM, Kim CC, Batra S, Rocha C, Balmaseda A, Harris E. 2010 Gene expression patterns of dengue virus-infected children from Nicaragua reveal a distinct signature of increased metabolism. PLoS Neglected Trop. Dis. 4, e710. (doi:10.1371/journal. pntd.0000710)
    • (2010) PLoS Neglected Trop. Dis. , vol.4
    • Loke, P.1    Hammond, S.N.2    Leung, J.M.3    Kim, C.C.4    Batra, S.5    Rocha, C.6    Balmaseda, A.7    Harris, E.8
  • 36
    • 84880893484 scopus 로고    scopus 로고
    • Transcriptomic analysis of peripheral blood mononuclear cells in rapid progressors in early HIV infection identifies a signature closely correlated with disease progression
    • (doi:10. 1373/clinchem.2012.197335)
    • Zhang ZN et al. 2013 Transcriptomic analysis of peripheral blood mononuclear cells in rapid progressors in early HIV infection identifies a signature closely correlated with disease progression. Clin. Chem. 59, 1175-1186. (doi:10. 1373/clinchem.2012.197335)
    • (2013) Clin. Chem. , vol.59 , pp. 1175-1186
    • Zhang, Z.N.1
  • 37
    • 79960883949 scopus 로고    scopus 로고
    • Comparative expression profile of miRNA and mRNA in primary peripheral blood mononuclear cells infected with human immunodeficiency virus (HIV-1)
    • (doi:10.1371/journal.pone. 0022730)
    • Gupta A, Nagilla P, Le HS, Bunney C, Zych C, Thalamuthu A, Bar-Joseph Z, Mathavan S, Ayyavoo V. 2011 Comparative expression profile of miRNA and mRNA in primary peripheral blood mononuclear cells infected with human immunodeficiency virus (HIV-1). PLoS ONE 6, e22730. (doi:10.1371/journal.pone. 0022730)
    • (2011) PLoS ONE , vol.6
    • Gupta, A.1    Nagilla, P.2    Le, H.S.3    Bunney, C.4    Zych, C.5    Thalamuthu, A.6    Bar-Joseph, Z.7    Mathavan, S.8    Ayyavoo, V.9
  • 38
    • 84875425732 scopus 로고    scopus 로고
    • Type I interferon suppresses type II interferon-triggered human antimycobacterial responses
    • (doi:10.1126/science.1233665)
    • Teles RM et al. 2013 Type I interferon suppresses type II interferon-triggered human antimycobacterial responses. Science 339, 1448-1453. (doi:10.1126/science.1233665)
    • (2013) Science , vol.339 , pp. 1448-1453
    • Teles, R.M.1
  • 39
    • 65549116870 scopus 로고    scopus 로고
    • Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections
    • (doi:10.1371/journal. pone.0005446)
    • Ardura MI et al. 2009 Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections. PLoS ONE 4, e5446. (doi:10.1371/journal. pone.0005446)
    • (2009) PLoS ONE , vol.4
    • Ardura, M.I.1
  • 40
    • 84862781158 scopus 로고    scopus 로고
    • Transcriptome signature in young children with acute otitis media due to Streptococcus pneumoniae
    • (doi:10. 1016/j.micinf.2012.01.006)
    • Liu K, Chen L, Kaur R, Pichichero M. 2012 Transcriptome signature in young children with acute otitis media due to Streptococcus pneumoniae. Microbes Infect. Inst. Pasteur 14, 600-609. (doi:10. 1016/j.micinf.2012.01.006)
    • (2012) Microbes Infect. Inst. Pasteur , vol.14 , pp. 600-609
    • Liu, K.1    Chen, L.2    Kaur, R.3    Pichichero, M.4
  • 41
    • 76049124789 scopus 로고    scopus 로고
    • Transcriptional response in the peripheral blood of patients infected with Salmonella enterica serovar Typhi
    • (doi:10.1073/pnas. 0912386106)
    • Thompson LJ et al. 2009 Transcriptional response in the peripheral blood of patients infected with Salmonella enterica serovar Typhi. Proc. Natl Acad. Sci. USA 106, 22 433-22 438. (doi:10.1073/pnas. 0912386106)
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 22433-22438
    • Thompson, L.J.1
  • 42
    • 34249948116 scopus 로고    scopus 로고
    • Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis
    • (doi:10.1007/s00109-007-0157-6)
    • Jacobsen M, Repsilber D, Gutschmidt A, Neher A, Feldmann K, Mollenkopf HJ, Ziegler A, Kaufmann SH. 2007 Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis. J. Mol. Med. 85, 613-621. (doi:10.1007/s00109-007-0157-6)
    • (2007) J. Mol. Med. , vol.85 , pp. 613-621
    • Jacobsen, M.1    Repsilber, D.2    Gutschmidt, A.3    Neher, A.4    Feldmann, K.5    Mollenkopf, H.J.6    Ziegler, A.7    Kaufmann, S.H.8
  • 43
    • 33846405255 scopus 로고    scopus 로고
    • Gene-expression patterns in whole blood identify subjects at risk for recurrent tuberculosis
    • (doi:10. 1086/510397)
    • Mistry R et al. 2007 Gene-expression patterns in whole blood identify subjects at risk for recurrent tuberculosis. J. Infect. Dis. 195, 357-365. (doi:10. 1086/510397)
    • (2007) J. Infect. Dis. , vol.195 , pp. 357-365
    • Mistry, R.1
  • 45
    • 80052726604 scopus 로고    scopus 로고
    • Transcriptional responses of host peripheral blood cells to tuberculosis infection
    • (doi:10.1016/j.tube. 2011.07.002)
    • Lesho E et al. 2011 Transcriptional responses of host peripheral blood cells to tuberculosis infection. Tuberculosis 91, 390-399. (doi:10.1016/j.tube. 2011.07.002)
    • (2011) Tuberculosis , vol.91 , pp. 390-399
    • Lesho, E.1
  • 46
    • 80055042377 scopus 로고    scopus 로고
    • Functional correlations of pathogenesis-driven gene expression signatures in tuberculosis
    • (doi:10.1371/journal.pone.0026938)
    • Maertzdorf J, Ota M, Repsilber D, Mollenkopf HJ, Weiner J, Hill PC, Kaufmann SH. 2011 Functional correlations of pathogenesis-driven gene expression signatures in tuberculosis. PLoS ONE 6, e26938. (doi:10.1371/journal.pone.0026938)
    • (2011) PLoS ONE , vol.6
    • Maertzdorf, J.1    Ota, M.2    Repsilber, D.3    Mollenkopf, H.J.4    Weiner, J.5    Hill, P.C.6    Kaufmann, S.H.7
  • 48
    • 84872978097 scopus 로고    scopus 로고
    • Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response
    • (doi:10.1093/ infdis/jis499)
    • Cliff JM et al. 2013 Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response. J. Infect. Dis. 207, 18-29. (doi:10.1093/ infdis/jis499)
    • (2013) J. Infect. Dis. , vol.207 , pp. 18-29
    • Cliff, J.M.1
  • 49
    • 84886613855 scopus 로고    scopus 로고
    • Detection of tuberculosis in HIV-infected and-uninfected African adults using whole blood RNA expression signatures: A case-control study
    • (doi:10. 1371/journal.pmed.1001538)
    • Kaforou M et al. 2013 Detection of tuberculosis in HIV-infected and-uninfected African adults using whole blood RNA expression signatures: a case-control study. PLoS Med. 10, e1001538. (doi:10. 1371/journal.pmed.1001538)
    • (2013) PLoS Med. , vol.10
    • Kaforou, M.1
  • 50
    • 57849085182 scopus 로고    scopus 로고
    • Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
    • (doi:10. 1038/ni.1688)
    • Querec TD et al. 2009 Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat. Immunol. 10, 116-125. (doi:10. 1038/ni.1688)
    • (2009) Nat. Immunol. , vol.10 , pp. 116-125
    • Querec, T.D.1
  • 52
    • 84870370352 scopus 로고    scopus 로고
    • Annonymous, Geneva, Switzerland: World Health Organisation
    • Annonymous. 2012 Global tuberculosis report 2012. Geneva, Switzerland: World Health Organisation.
    • (2012) Global tuberculosis report 2012
  • 53
    • 78650088377 scopus 로고    scopus 로고
    • Annonymous, Geneva, Switzerland: World Health Organisation
    • Annonymous. 2010 The global plan to Stop TB 2011-2015. Geneva, Switzerland: World Health Organisation.
    • (2010) The global plan to Stop TB 2011-2015
  • 54
    • 0034255547 scopus 로고    scopus 로고
    • Lifetime risks, incubation period, and serial interval of tuberculosis
    • (doi:10.1093/aje/ 152.3.247)
    • Vynnycky E, Fine PE. 2000 Lifetime risks, incubation period, and serial interval of tuberculosis. Am. J. Epidemiol. 152, 247-263. (doi:10.1093/aje/ 152.3.247)
    • (2000) Am. J. Epidemiol. , vol.152 , pp. 247-263
    • Vynnycky, E.1    Fine, P.E.2
  • 56
    • 0344609266 scopus 로고    scopus 로고
    • Tuberculosis in patients with human immunodeficiency virus infection
    • (doi:10.1056/ NEJM199902043400507)
    • Havlir DV, Barnes PF. 1999 Tuberculosis in patients with human immunodeficiency virus infection. N. Engl. J. Med. 340, 367-373. (doi:10.1056/ NEJM199902043400507)
    • (1999) N. Engl. J. Med. , vol.340 , pp. 367-373
    • Havlir, D.V.1    Barnes, P.F.2
  • 57
    • 33748563580 scopus 로고    scopus 로고
    • Adverse events and treatment interruption in tuberculosis patients with and without HIV co-infection
    • (doi:10.1136/thx.2006.058867)
    • Breen RA et al. 2006 Adverse events and treatment interruption in tuberculosis patients with and without HIV co-infection. Thorax 61, 791-794. (doi:10.1136/thx.2006.058867)
    • (2006) Thorax , vol.61 , pp. 791-794
    • Breen, R.A.1
  • 58
    • 84875868248 scopus 로고    scopus 로고
    • Vaccination against tuberculosis: How can we better BCG?
    • (doi:10.1016/j. micpath.2012.12.002)
    • Pitt JM, Blankley S, McShane H, O'Garra A. 2013 Vaccination against tuberculosis: how can we better BCG? Microb. Pathog. 58, 2-16. (doi:10.1016/j. micpath.2012.12.002)
    • (2013) Microb. Pathog. , vol.58 , pp. 2-16
    • Pitt, J.M.1    Blankley, S.2    McShane, H.3    O'Garra, A.4
  • 59
    • 0028153628 scopus 로고
    • Efficacy of BCG vaccine in the prevention of tuberculosis. Metaanalysis of the published literature
    • (doi:10.1001/jama.1994. 03510330076038)
    • Colditz GA, Brewer TF, Berkey CS, Wilson ME, Burdick E, Fineberg HV, Mosteller F. 1994 Efficacy of BCG vaccine in the prevention of tuberculosis. Metaanalysis of the published literature. J. Am. Med. Assoc. 271, 698-702. (doi:10.1001/jama.1994. 03510330076038)
    • (1994) J. Am. Med. Assoc. , vol.271 , pp. 698-702
    • Colditz, G.A.1    Brewer, T.F.2    Berkey, C.S.3    Wilson, M.E.4    Burdick, E.5    Fineberg, H.V.6    Mosteller, F.7
  • 60
    • 0028872014 scopus 로고
    • Variation in protection by BCG: Implications of and for heterologous immunity
    • (doi:10.1016/S0140-6736(95)92348-9)
    • Fine PE. 1995 Variation in protection by BCG: implications of and for heterologous immunity. Lancet 346, 1339-1345. (doi:10.1016/S0140-6736(95)92348-9)
    • (1995) Lancet , vol.346 , pp. 1339-1345
    • Fine, P.E.1
  • 61
    • 84893324684 scopus 로고    scopus 로고
    • Protection by BCG against tuberculosis: A systematic review of randomised controlled trials
    • (doi:10.1093/cid/cit790)
    • Mangtani P et al. 2013 Protection by BCG against tuberculosis: a systematic review of randomised controlled trials. Clin. Infect. Dis. 58, 470-480. (doi:10.1093/cid/cit790)
    • (2013) Clin. Infect. Dis. , vol.58 , pp. 470-480
    • Mangtani, P.1
  • 62
    • 77958475885 scopus 로고    scopus 로고
    • Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guerin vaccination of newborns
    • (doi:10.1164/rccm.201003-0334OC)
    • Kagina BM et al. 2010 Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guerin vaccination of newborns. Am. J. Respir. Crit. Care Med. 182, 1073-1079. (doi:10.1164/rccm.201003-0334OC)
    • (2010) Am. J. Respir. Crit. Care Med. , vol.182 , pp. 1073-1079
    • Kagina, B.M.1
  • 63
    • 84862640434 scopus 로고    scopus 로고
    • Tuberculosis vaccine development: Strength lies in tenacity
    • (doi:10.1016/j.it.2012. 03.004)
    • Kaufmann SH. 2012 Tuberculosis vaccine development: strength lies in tenacity. Trends Immunol. 33, 373-379. (doi:10.1016/j.it.2012. 03.004)
    • (2012) Trends Immunol. , vol.33 , pp. 373-379
    • Kaufmann, S.H.1
  • 64
    • 84875382846 scopus 로고    scopus 로고
    • Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: A randomised, placebo-controlled phase 2b trial
    • (doi:10.1016/S0140-6736(13) 60177-4)
    • Tameris MD et al. 2013 Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial. Lancet 381, 1021-1028. (doi:10.1016/S0140-6736(13) 60177-4)
    • (2013) Lancet , vol.381 , pp. 1021-1028
    • Tameris, M.D.1
  • 65
    • 79957470148 scopus 로고    scopus 로고
    • Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCGvaccinated infants
    • (doi:10.1093/infdis/jir195)
    • Scriba TJ et al. 2011 Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCGvaccinated infants. J. Infect. Dis. 203, 1832-1843. (doi:10.1093/infdis/jir195)
    • (2011) J. Infect. Dis. , vol.203 , pp. 1832-1843
    • Scriba, T.J.1
  • 66
    • 65349186494 scopus 로고    scopus 로고
    • MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques
    • (doi:10.1371/journal.pone. 0005264)
    • Verreck FA et al. 2009 MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques. PLoS ONE 4, e5264. (doi:10.1371/journal.pone. 0005264)
    • (2009) PLoS ONE , vol.4
    • Verreck, F.A.1
  • 67
    • 84898018651 scopus 로고    scopus 로고
    • Systems approaches to studying the immune response in tuberculosis
    • (doi:10.1016/j.coi.2013. 08.003)
    • Berry MP, Blankley S, Graham CM, Bloom CI, O'Garra A. 2013 Systems approaches to studying the immune response in tuberculosis. Curr. Opin. Immunol. 25, 579-587. (doi:10.1016/j.coi.2013. 08.003)
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 579-587
    • Berry, M.P.1    Blankley, S.2    Graham, C.M.3    Bloom, C.I.4    O'Garra, A.5
  • 68
    • 80052313144 scopus 로고    scopus 로고
    • Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells
    • (doi:10. 1371/journal.pone.0024290)
    • Lu C et al. 2011 Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells. PLoS ONE 6, e24290. (doi:10. 1371/journal.pone.0024290)
    • (2011) PLoS ONE , vol.6
    • Lu, C.1
  • 69
    • 0035826721 scopus 로고    scopus 로고
    • Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha/beta
    • (doi:10.1073/ pnas.091096998)
    • Manca C, Tsenova L, Bergtold A, Freeman S, Tovey M, Musser JM, Barry 3rd CE, Freedman VH, Kaplan G. 2001 Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha/beta. Proc. Natl Acad. Sci. USA 98, 5752-5757. (doi:10.1073/ pnas.091096998)
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 5752-5757
    • Manca, C.1    Tsenova, L.2    Bergtold, A.3    Freeman, S.4    Tovey, M.5    Musser, J.M.6    Barry III, C.E.7    Freedman, V.H.8    Kaplan, G.9
  • 70
    • 29444432905 scopus 로고    scopus 로고
    • Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway
    • (doi:10. 1089/jir.2005.25.694)
    • Manca C, Tsenova L, Freeman S, Barczak AK, Tovey M, Murray PJ, Barry C, Kaplan G. 2005 Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway. J. Interferon Cytokine Res. 25, 694-701. (doi:10. 1089/jir.2005.25.694)
    • (2005) J. Interferon Cytokine Res. , vol.25 , pp. 694-701
    • Manca, C.1    Tsenova, L.2    Freeman, S.3    Barczak, A.K.4    Tovey, M.5    Murray, P.J.6    Barry, C.7    Kaplan, G.8
  • 71
    • 84884179172 scopus 로고    scopus 로고
    • A helicopter perspective on TB biomarkers: Pathway and process based analysis of gene expression data provides new insight into TB pathogenesis
    • (doi:10.1371/ journal.pone.0073230)
    • Joosten SA, Fletcher HA, Ottenhoff TH. 2013 A helicopter perspective on TB biomarkers: pathway and process based analysis of gene expression data provides new insight into TB pathogenesis. PLoS ONE 8, e73230. (doi:10.1371/ journal.pone.0073230)
    • (2013) PLoS ONE , vol.8
    • Joosten, S.A.1    Fletcher, H.A.2    Ottenhoff, T.H.3
  • 72
    • 81455150139 scopus 로고    scopus 로고
    • Sarcoidosis blood transcriptome reflects lung inflammation and overlaps with tuberculosis
    • (doi:10.1164/rccm.201106-1143OC)
    • Koth LL, Solberg OD, Peng JC, Bhakta NR, Nguyen CP, Woodruff PG. 2011 Sarcoidosis blood transcriptome reflects lung inflammation and overlaps with tuberculosis. Am. J. Respir. Crit. Care Med. 184, 1153-1163. (doi:10.1164/rccm.201106-1143OC)
    • (2011) Am. J. Respir. Crit. Care Med. , vol.184 , pp. 1153-1163
    • Koth, L.L.1    Solberg, O.D.2    Peng, J.C.3    Bhakta, N.R.4    Nguyen, C.P.5    Woodruff, P.G.6
  • 73
    • 84898618335 scopus 로고    scopus 로고
    • Comparison of RNA-Seq and microarray in transcriptome profiling of activated T cells
    • (doi:10.1371/journal.pone. 0078644)
    • Zhao S, Fung-Leung WP, Bittner A, Ngo K, Liu X. 2014 Comparison of RNA-Seq and microarray in transcriptome profiling of activated T cells. PLoS ONE 9, e78644. (doi:10.1371/journal.pone. 0078644)
    • (2014) PLoS ONE , vol.9
    • Zhao, S.1    Fung-Leung, W.P.2    Bittner, A.3    Ngo, K.4    Liu, X.5
  • 74
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: A revolutionary tool for transcriptomics
    • (doi:10.1038/nrg2484)
    • Wang Z, Gerstein M, Snyder M. 2009 RNA-Seq: a revolutionary tool for transcriptomics. Nat. Rev. Genet. 10, 57-63. (doi:10.1038/nrg2484)
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 75
    • 84870602117 scopus 로고    scopus 로고
    • Accurate diagnostics for bovine tuberculosis based on high-throughput sequencing
    • (doi:10.1371/ journal.pone.0050147)
    • Churbanov A, Milligan B. 2012 Accurate diagnostics for bovine tuberculosis based on high-throughput sequencing. PLoS ONE 7, e50147. (doi:10.1371/ journal.pone.0050147)
    • (2012) PLoS ONE , vol.7
    • Churbanov, A.1    Milligan, B.2
  • 76
    • 84900333650 scopus 로고    scopus 로고
    • Milestone approval lifts Illumina's NGS from research into clinic
    • (doi:10.1038/ nbt0214-111)
    • Sheridan C. 2014 Milestone approval lifts Illumina's NGS from research into clinic. Nat. Biotechnol. 32, 111-112. (doi:10.1038/ nbt0214-111)
    • (2014) Nat. Biotechnol. , vol.32 , pp. 111-112
    • Sheridan, C.1
  • 77
    • 84881169742 scopus 로고    scopus 로고
    • Mining large-scale response networks reveals 'topmost activities' in Mycobacterium tuberculosis infection
    • (doi:10. 1038/srep02302)
    • Sambarey A, Prashanthi K, Chandra N. 2013 Mining large-scale response networks reveals 'topmost activities' in Mycobacterium tuberculosis infection. Sci. Rep. 3, 2302. (doi:10. 1038/srep02302)
    • (2013) Sci. Rep. , vol.3 , pp. 2302
    • Sambarey, A.1    Prashanthi, K.2    Chandra, N.3


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