Differences in global gene expression in peripheral blood mononuclear cells indicate a significant role of the innate responses in progression of dengue fever but not dengue hemorrhagic fever

Journal of Infectious Diseases

Volumn 197, Issue 10, 2008, Pages 1459-1467

  Ubol, Sukathida ^a   Masrinoul, Promsin ^a   Chaijaruwanich, Jeerayut ^c   Kalayanarooj, Siripen ^b   Charoensirisuthikul, Takol ^a   Kasisith, Jitra ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b QUEEN SIRIKIT NATIONAL INSTITUTE OF CHILD HEALTH   (Thailand)

^c CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN; CATHEPSIN L; CD59 ANTIGEN; COMPLEMENT INHIBITOR; CXCL1 CHEMOKINE; GALECTIN 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN FC FRAGMENT; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 21 RECEPTOR; INTERLEUKIN 8; LECTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; PROTEASOME; SERINE PROTEINASE INHIBITOR; TRANSCRIPTOME; TUMOR NECROSIS FACTOR RECEPTOR; X BOX BINDING PROTEIN 1;

ANTIBODY TITER; APOPTOSIS; ARTICLE; B LYMPHOCYTE ACTIVATION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMOGRAPHY; DENGUE; DENGUE VIRUS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; MICROARRAY ANALYSIS; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SEROTYPE; T LYMPHOCYTE ACTIVATION;

CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; COMPLEMENT SYSTEM PROTEINS; CYTOKINES; DENGUE; DENGUE HEMORRHAGIC FEVER; DENGUE VIRUS; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY, NATURAL; LEUKOCYTES, MONONUCLEAR; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 44049104994     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/587699     Document Type: Article

References (50)

1. Holmes EC, Twiddy SS. The origin, emergence and evolutionary genetics of dengue virus. Infect Genet Evol 2003; 3:19-28.
2. Guzmán M, Kourí G, Díaz M, et al. Dengue, one of the great emerging health challenges of the 21st century. Expert Rev Vaccines 2004; 3:511-20.
3. Green S, Rothman A. Immunopathological mechanisms in dengue and dengue hemorrhagic fever. Curr Opin Infect Dis 2006; 19:429-36.
4. Vaughn DW, Green S, Kalayanarooj S, et al. Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J Infect Dis 2000; 181:2-9.
5. Libraty DH, Young PR, Pickering D, et al. High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever. J Infect Dis 2002; 186:1165-8.
6. Chareonsirisuthigul T, Kalayanarooj S, Ubol S. Dengue virus (DENV) antibody-dependent enhancement of infection upregulates the production of anti-inflammatory cytokines, but suppresses anti-DENV free radical and pro-inflammatory cytokine production, in THP-1 cells. J Gen Virol 2007; 88:365-75.
7. + T cells display quantitative and qualitative differences in their response to variant epitopes of heterologous viral serotypes. J Immunol 2006; 176:2817-24.
8. high regulatory T cells in acute dengue infection. J Exp Med 2007; 204:979-85.
9. Palmer DR, Sun P, Celluzzi C, et al. Differential effects of dengue virus on infected and bystander dendritic cells. J Virol 2005; 79:2432-9.
10. Srikiatkhachorn A, Ajariyakhajorn C, Endy TP, et al. Virus-induced decline in soluble vascular endothelial growth receptor 2 is associated with plasma leakage in dengue hemorrhagic fever. J Virol 2007; 81:1592- 600.
11. Srichaikul T, Nimmannitya S. Haematology in dengue and dengue haemorrhagic fever. Baillieres Best Pract Res Clin Haematol 2000; 13:261-76.
12. Chantharakassi U, Malasit P, Innis BL. Time dependent effects of dengue virus on platelets: a cyclo-oxygenase dependent mechanism [abstract]. Southeast Asian J Trop Med Public Health 1990; 21:706
13. Lockhart DJ, Winzeler EA. Genomics, gene expression and DNA arrays. Nature 2000; 405:827-36.
14. Kobasa D, Jones SM, Shinya K, et al. Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature 2007; 445:319-23.
15. Pugazhendhi D, Sadler AJ, Darbre PD. Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17β-oestradiol in MCF7 human breast cancer cells. J Appl Toxicol 2007; 27:67-77.
16. Lanciotti RS, Calisher CH, Gubler D, Chang GJ, Vorndam AV. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 1992; 30:545-51.
17. Houng HH, Chung-Ming R, Vaughn DW, Kanesa-Thasan N. Development of a fluorogenic RT-PCR system for quantitative identification of dengue virus serotypes 1-4 using conserved and serotype-specific 3′ noncoding sequence. J Virol Med 2001; 95:19-23.
18. Sa-Ngsang A, Anantapreecha S, A-Nuegoonpipat A, et al. Specific IgM and IgG responses in primary and secondary dengue virus infection determined by enzyme-linked immunosorbant assay. Epidemiol Infect 2006; 134:820-5.
19. Shresta S, Kyle JL, Snider HM, et al. Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical. J Virol 2004; 78:2701-10.
20. Shresta S, Sharar KL, Prigozhin DM, et al. Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice. J Immunol 2005; 175:3946-54.
21. Chen LC, Lei HY, Liu CC, et al. Correlation of serum levels of macrophage migration inhibitory factor with disease severity and clinical outcome in dengue patients. Am J Trop Med Hyg 2006; 74:142-7.
22. Simmons CP, Popper S, Dolocek C, et al. Patterns of host genome-wide gene transcript abundance in the peripheral blood of patients with acute dengue hemorrhagic fever. J Infect Dis 2007; 195:1097-107.
23. Fujita T. Sensing viral RNA amid your own. Science 2006; 314:935-6
24. Kato H, Takeuchi O, Sato S, et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006; 441:101-5.
25. Berghäll H, Sirén J, Sarkar D, et al. The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines. Microbes Infect 2006; 8:2138-44.
26. Martensen PM, Justesen J. Small ISGs coming forward. J Interferon Cytokine Res 2004; 24:1-19.
27. Lenschow DJ, Lai C, Frias-Staheli N, et al. IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proc Natl Acad Sci USA 2007; 104:1371-6.
28. Wacher C, Müller M, Hofer MJ, et al. Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses. J Virol 2007; 81:860-71.
29. Taub DD, Lloyd AR, Conlon K, et al. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med 1993; 177:1809-14.
30. Taub DD, Sayers TJ, Carter CR, Ortaldo JR. Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis. J Immunol 1995; 155:3877-88.
31. Trifilo MJ, Montalto-Morrison C, Stiles LN, et al. CXC chemokine ligand 10 controls viral infection in the central nervous system: evidence for a role in innate immune response through recruitment and activation of natural killer cells. J Virol 2004; 78:585-94.
32. Bhowmick S, Duseja R, Das S, Appaiahgiri MB, Vrati S, Basu A. Induction of IP-10 (CXCL10) in astrocytes following Japanese encephalitis. Neurosci Lett 2007; 414:45-50.
33. Hsieh MF, Lai SL, Chen JP, et al. Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus. J Immunol 2006; 177:1855-63.
34. Chen JP, Lu HL, Lai SL, et al. Dengue virus induces expression of CXC chemokine ligand 10/IFN-γ-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate. J Immunol 2006; 177:3185-92.
35. Avirutnan P, Punyadee N, Noisakarn S, et al. Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement. J Infect Dis 2006; 193:1078-88.
36. Morgan BP. Effects of the membrane attack complex of complement on nucleated cells. Curr Top Microbiol Immunol 1992; 178:115-40.
37. Cole DS, Hughes TR, Gasque P, Morgan BP. Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis. Mol Immunol 2006; 43:1953-64.
38. Harris CL, Pettigrew DM, Lea SM, Morgan BP. Decay-accelerating factor must bind both components of the complement alternative pathway C3 convertase to mediate efficient decay. J Immunol 2007; 178:352-9.
39. Pang T, Cardosa MJ, Guzman MG. Of cascades and perfect storms: the immunopathogenesis of dengue haemorrhagic fever-dengue shock syndrome (DHF/DSS). Immunol Cell Biol 2007; 85:43-5.
40. Sturm A, Lensch M, André S, et al. Human galectin-2: novel inducer of T cell apoptosis with distinct profile of caspase activation. J Immunol 2004; 173:3825-37.
41. Conti P, Youinou P, Theoharides TC. Modulation of autoimmunity by the latest interleukins (with special emphasis on IL-32). Autoimmun Rev 2007; 6:131-7.
42. Kohler C, Håkansson A, Svanborg C, Orrenius S, Zhivotovsky B. Protease activation in apoptosis induced by MAL. Exp Cell Res 1999; 249:260-8.
43. Mongkolsapaya J, Dejnirattisai W, Xu XN, et al. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med 2003; 9:921-7.
44. Chaturvedi UC, Agarwal R, Elbishbishi EA, Mustafa SA. Cytokine cascade in dengue hemorrhagic fever: implications for pathogenesis. FEMS Immunol Med Microbiol 2000; 28:183-8.
45. Rothman AL. Immunology and immunopathogenesis of dengue disease. Adv Virus Res 2003; 60:397-419.
46. Nguyen TH, Nguyen TL, Lei HY, et al. Association between sex, nutritional status, severity of dengue hemorrhagic fever, and immune status in infants with dengue hemorrhagic fever. Am J Trop Med Hyg 2005; 72:370-4.
47. Nguyen TH, Lei HY, Nguyen TL, et al. Dengue hemorrhagic fever in infants: a study of clinical and cytokine profiles. J Infect Dis 2004; 189:221-32.
48. Chaturvedi UC, Nagar R, Shrivastava R. Dengue and dengue hemorrhagic fever: implication of host genetics. FEMS Immunol Med Microbiol 2006; 47:155-66.
49. LaFleur C, Granados J, Vargas-Alarcon G, et al. HLA-DR antigen frequencies in Mexican patients with dengue virus infection: HLA-DR4 as a possible genetic resistance factor for dengue hemorrhagic fever. Hum Immunol 2002; 63:1039-44.
50. Polizel JR, Bueno D, Visentainer JEL, et al. Association of human leukocyte antigen DQ1 and dengue fever in a white Southern Brazillian population. Men Inst Oswaldo Cruz 2004; 99:559-62.