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Volumn 44, Issue 4, 2015, Pages 1909-1923

Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL FACTOR; EUKARYOTIC RELEASE FACTOR 3; RNA HELICASE; SURF COMPLEX; UNCLASSIFIED DRUG; UP FRAMESHIFT 2 PROTEIN; UP FRAMESHIFT 3 PROTEIN; UP FRAMESHIFT 3B PROTEIN; MULTIPROTEIN COMPLEX; PEPTIDE-CHAIN-RELEASE FACTOR 3; PROTEIN BINDING; STOP CODON; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSLATION TERMINATION FACTOR; UPF2 PROTEIN, HUMAN;

EID: 84960489994     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv1527     Document Type: Article
Times cited : (39)

References (55)
  • 1
    • 84867850145 scopus 로고    scopus 로고
    • NMD: A multifaceted response to premature translational termination
    • Kervestin, S. and Jacobson, A. (2012) NMD: a multifaceted response to premature translational termination. Nat. Rev. Mol. Cell Biol., 13, 700-712.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 700-712
    • Kervestin, S.1    Jacobson, A.2
  • 2
    • 84877818178 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay-mechanisms of substrate mRNA recognition and degradation in mammalian cells
    • Schweingruber, C., Rufener, S.C., Zund, D., Yamashita, A. and Muhlemann, O. (2013) Nonsense-mediated mRNA decay-mechanisms of substrate mRNA recognition and degradation in mammalian cells. Biochim. Biophys. Acta, 1829, 612-623.
    • (2013) Biochim. Biophys. Acta , vol.1829 , pp. 612-623
    • Schweingruber, C.1    Rufener, S.C.2    Zund, D.3    Yamashita, A.4    Muhlemann, O.5
  • 3
    • 84874217508 scopus 로고    scopus 로고
    • Role of SMG-1-mediated Upf1 phosphorylation in mammalian nonsense-mediated mRNA decay
    • Yamashita, A. (2013) Role of SMG-1-mediated Upf1 phosphorylation in mammalian nonsense-mediated mRNA decay. Genes Cells, 18, 161-175.
    • (2013) Genes Cells , vol.18 , pp. 161-175
    • Yamashita, A.1
  • 4
    • 34249870085 scopus 로고    scopus 로고
    • MRNA quality control: An ancient machinery recognizes and degrades mRNAs with nonsense codons
    • Behm-Ansmant, I., Kashima, I., Rehwinkel, J., Sauliere, J., Wittkopp, N. and Izaurralde, E. (2007) mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons. FEBS Lett., 581, 2845-2853.
    • (2007) FEBS Lett. , vol.581 , pp. 2845-2853
    • Behm-Ansmant, I.1    Kashima, I.2    Rehwinkel, J.3    Sauliere, J.4    Wittkopp, N.5    Izaurralde, E.6
  • 5
    • 84945442257 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay: An intricate machinery that shapes transcriptomes
    • Lykke-Andersen, S. and Jensen, T.H. (2015) Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes. Nat. Rev. Mol. Cell Biol., 16, 665-677.
    • (2015) Nat. Rev. Mol. Cell Biol. , vol.16 , pp. 665-677
    • Lykke-Andersen, S.1    Jensen, T.H.2
  • 6
    • 84948744028 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay: Degradation of defective transcripts is only part of the story
    • He, F. and Jacobson, A. (2015) Nonsense-mediated mRNA decay: degradation of defective transcripts is only part of the story. Annu. Rev. Genet., 49, 339-366.
    • (2015) Annu. Rev. Genet. , vol.49 , pp. 339-366
    • He, F.1    Jacobson, A.2
  • 7
    • 84930864711 scopus 로고    scopus 로고
    • RNA degradation drives stem cell differentiation
    • Lou, C.H., Shum, E.Y. and Wilkinson, M.F. (2015) RNA degradation drives stem cell differentiation. EMBO J., 34, 1606-1608.
    • (2015) EMBO J. , vol.34 , pp. 1606-1608
    • Lou, C.H.1    Shum, E.Y.2    Wilkinson, M.F.3
  • 9
    • 65449178454 scopus 로고    scopus 로고
    • SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay
    • Yamashita, A., Izumi, N., Kashima, I., Ohnishi, T., Saari, B., Katsuhata, Y., Muramatsu, R., Morita, T., Iwamatsu, A., Hachiya, T. et al. (2009) SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. Genes Dev., 23, 1091-1105.
    • (2009) Genes Dev. , vol.23 , pp. 1091-1105
    • Yamashita, A.1    Izumi, N.2    Kashima, I.3    Ohnishi, T.4    Saari, B.5    Katsuhata, Y.6    Muramatsu, R.7    Morita, T.8    Iwamatsu, A.9    Hachiya, T.10
  • 10
    • 32044435368 scopus 로고    scopus 로고
    • Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay
    • Kashima, I., Yamashita, A., Izumi, N., Kataoka, N., Morishita, R., Hoshino, S., Ohno, M., Dreyfuss, G. and Ohno, S. (2006) Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes Dev., 20, 355-367.
    • (2006) Genes Dev. , vol.20 , pp. 355-367
    • Kashima, I.1    Yamashita, A.2    Izumi, N.3    Kataoka, N.4    Morishita, R.5    Hoshino, S.6    Ohno, M.7    Dreyfuss, G.8    Ohno, S.9
  • 11
    • 84885069820 scopus 로고    scopus 로고
    • Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay
    • Hurt, J.A., Robertson, A.D. and Burge, C.B. (2013) Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay. Genome Res., 23, 1636-1650.
    • (2013) Genome Res. , vol.23 , pp. 1636-1650
    • Hurt, J.A.1    Robertson, A.D.2    Burge, C.B.3
  • 12
    • 84874504687 scopus 로고    scopus 로고
    • Rules that govern UPF1 binding to mRNA 3' UTRs
    • Kurosaki, T. and Maquat, L.E. (2013) Rules that govern UPF1 binding to mRNA 3' UTRs. Proc. Natl. Acad. Sci. U.S.A., 110, 3357-3362.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 3357-3362
    • Kurosaki, T.1    Maquat, L.E.2
  • 13
    • 84881477715 scopus 로고    scopus 로고
    • Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3' UTRs
    • Zund, D., Gruber, A.R., Zavolan, M. and Muhlemann, O. (2013) Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3' UTRs. Nat. Struct. Mol. Biol., 20, 936-943.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 936-943
    • Zund, D.1    Gruber, A.R.2    Zavolan, M.3    Muhlemann, O.4
  • 17
    • 84940478899 scopus 로고    scopus 로고
    • Structural basis for stop codon recognition in eukaryotes
    • Brown, A., Shao, S., Murray, J., Hegde, R.S. and Ramakrishnan, V. (2015) Structural basis for stop codon recognition in eukaryotes. Nature, 524, 493-496.
    • (2015) Nature , vol.524 , pp. 493-496
    • Brown, A.1    Shao, S.2    Murray, J.3    Hegde, R.S.4    Ramakrishnan, V.5
  • 19
    • 21744448013 scopus 로고    scopus 로고
    • Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation
    • Chauvin, C., Salhi, S., Le Goff, C., Viranaicken, W., Diop, D. and Jean-Jean, O. (2005) Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation. Mol. Cell. Biol., 25, 5801-5811.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 5801-5811
    • Chauvin, C.1    Salhi, S.2    Le Goff, C.3    Viranaicken, W.4    Diop, D.5    Jean-Jean, O.6
  • 23
    • 37849005006 scopus 로고    scopus 로고
    • NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity
    • Chamieh, H., Ballut, L., Bonneau, F. and Le Hir, H. (2008) NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity. Nat. Struct. Mol. Biol., 15, 85-93.
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 85-93
    • Chamieh, H.1    Ballut, L.2    Bonneau, F.3    Le Hir, H.4
  • 24
    • 40949148553 scopus 로고    scopus 로고
    • Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways
    • Ivanov, P.V., Gehring, N.H., Kunz, J.B., Hentze, M.W. and Kulozik, A.E. (2008) Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways. EMBO J., 27, 736-747.
    • (2008) EMBO J. , vol.27 , pp. 736-747
    • Ivanov, P.V.1    Gehring, N.H.2    Kunz, J.B.3    Hentze, M.W.4    Kulozik, A.E.5
  • 25
    • 0035449691 scopus 로고    scopus 로고
    • Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay
    • Yamashita, A., Ohnishi, T., Kashima, I., Taya, Y. and Ohno, S. (2001) Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay. Genes Dev., 15, 2215-2228.
    • (2001) Genes Dev. , vol.15 , pp. 2215-2228
    • Yamashita, A.1    Ohnishi, T.2    Kashima, I.3    Taya, Y.4    Ohno, S.5
  • 27
    • 84907399845 scopus 로고    scopus 로고
    • The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex
    • Hug, N. and Caceres, J.F. (2014) The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex. Cell Rep., 8, 1845-1856.
    • (2014) Cell Rep. , vol.8 , pp. 1845-1856
    • Hug, N.1    Caceres, J.F.2
  • 28
    • 84895824865 scopus 로고    scopus 로고
    • Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2
    • Clerici, M., Deniaud, A., Boehm, V., Gehring, N.H., Schaffitzel, C. and Cusack, S. (2014) Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2. Nucleic Acids Res., 42, 2673-2686.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 2673-2686
    • Clerici, M.1    Deniaud, A.2    Boehm, V.3    Gehring, N.H.4    Schaffitzel, C.5    Cusack, S.6
  • 30
    • 84873526691 scopus 로고    scopus 로고
    • Structural insights into nonsense-mediated mRNA decay (NMD) by electron microscopy
    • Llorca, O. (2013) Structural insights into nonsense-mediated mRNA decay (NMD) by electron microscopy. Curr. Opin. Struct. Biol., 23, 161-167.
    • (2013) Curr. Opin. Struct. Biol. , vol.23 , pp. 161-167
    • Llorca, O.1
  • 31
    • 84905705220 scopus 로고    scopus 로고
    • Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD
    • Melero, R., Uchiyama, A., Castano, R., Kataoka, N., Kurosawa, H., Ohno, S., Yamashita, A. and Llorca, O. (2014) Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD. Structure, 22, 1105-1119.
    • (2014) Structure , vol.22 , pp. 1105-1119
    • Melero, R.1    Uchiyama, A.2    Castano, R.3    Kataoka, N.4    Kurosawa, H.5    Ohno, S.6    Yamashita, A.7    Llorca, O.8
  • 32
    • 1842473091 scopus 로고    scopus 로고
    • The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
    • Kadlec, J., Izaurralde, E. and Cusack, S. (2004) The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Nat. Struct. Mol. Biol., 11, 330-337.
    • (2004) Nat. Struct. Mol. Biol. , vol.11 , pp. 330-337
    • Kadlec, J.1    Izaurralde, E.2    Cusack, S.3
  • 34
    • 33744994837 scopus 로고    scopus 로고
    • EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3' UTR length
    • Buhler, M., Steiner, S., Mohn, F., Paillusson, A. and Muhlemann, O. (2006) EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3' UTR length. Nat. Struct. Mol. Biol., 13, 462-464.
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 462-464
    • Buhler, M.1    Steiner, S.2    Mohn, F.3    Paillusson, A.4    Muhlemann, O.5
  • 35
    • 43249093760 scopus 로고    scopus 로고
    • Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region
    • Eberle, A.B., Stalder, L., Mathys, H., Orozco, R.Z. and Muhlemann, O. (2008) Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region. PLoS Biol., 6, e92.
    • (2008) PLoS Biol. , vol.6 , pp. e92
    • Eberle, A.B.1    Stalder, L.2    Mathys, H.3    Orozco, R.Z.4    Muhlemann, O.5
  • 37
    • 0035865408 scopus 로고    scopus 로고
    • The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts
    • Wang, W., Czaplinski, K., Rao, Y. and Peltz, S.W. (2001) The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts. EMBO J., 20, 880-890.
    • (2001) EMBO J. , vol.20 , pp. 880-890
    • Wang, W.1    Czaplinski, K.2    Rao, Y.3    Peltz, S.W.4
  • 38
    • 84906239869 scopus 로고    scopus 로고
    • A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD
    • Nicholson, P., Josi, C., Kurosawa, H., Yamashita, A. and Muhlemann, O. (2014) A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD. Nucleic Acids Res., 42, 9217-9235.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 9217-9235
    • Nicholson, P.1    Josi, C.2    Kurosawa, H.3    Yamashita, A.4    Muhlemann, O.5
  • 39
    • 0032575550 scopus 로고    scopus 로고
    • Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1
    • Hoshino, S., Imai, M., Mizutani, M., Kikuchi, Y., Hanaoka, F., Ui, M. and Katada, T. (1998) Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1. J. Biol. Chem., 273, 22254-22259.
    • (1998) J. Biol. Chem. , vol.273 , pp. 22254-22259
    • Hoshino, S.1    Imai, M.2    Mizutani, M.3    Kikuchi, Y.4    Hanaoka, F.5    Ui, M.6    Katada, T.7
  • 40
    • 78651507958 scopus 로고    scopus 로고
    • The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8
    • Arias-Palomo, E., Yamashita, A., Fernandez, I.S., Nunez-Ramirez, R., Bamba, Y., Izumi, N., Ohno, S. and Llorca, O. (2011) The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8. Genes Dev., 25, 153-164.
    • (2011) Genes Dev. , vol.25 , pp. 153-164
    • Arias-Palomo, E.1    Yamashita, A.2    Fernandez, I.S.3    Nunez-Ramirez, R.4    Bamba, Y.5    Izumi, N.6    Ohno, S.7    Llorca, O.8
  • 41
    • 84856858152 scopus 로고    scopus 로고
    • N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD
    • Okada-Katsuhata, Y., Yamashita, A., Kutsuzawa, K., Izumi, N., Hirahara, F. and Ohno, S. (2012) N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD. Nucleic Acids Res., 40, 1251-1266.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 1251-1266
    • Okada-Katsuhata, Y.1    Yamashita, A.2    Kutsuzawa, K.3    Izumi, N.4    Hirahara, F.5    Ohno, S.6
  • 42
    • 84868444740 scopus 로고    scopus 로고
    • RELION: Implementation of a Bayesian approach to cryo-EM structure determination
    • Scheres, S.H. (2012) RELION: implementation of a Bayesian approach to cryo-EM structure determination. J. Struct. Biol., 180, 519-530.
    • (2012) J. Struct. Biol. , vol.180 , pp. 519-530
    • Scheres S. ., H.1
  • 44
    • 79952114848 scopus 로고    scopus 로고
    • 3-D structures of macromolecules using single-particle analysis in EMAN
    • Ludtke, S.J. (2010) 3-D structures of macromolecules using single-particle analysis in EMAN. Methods Mol. Biol., 673, 157-173.
    • (2010) Methods Mol. Biol. , vol.673 , pp. 157-173
    • Ludtke S. ., J.1
  • 45
    • 33845336533 scopus 로고    scopus 로고
    • Bsoft: Image processing and molecular modeling for electron microscopy
    • Heymann, J.B. and Belnap, D.M. (2007) Bsoft: image processing and molecular modeling for electron microscopy. J. Struct. Biol., 157, 3-18.
    • (2007) J. Struct. Biol. , vol.157 , pp. 3-18
    • Heymann, J.B.1    Belnap, D.M.2
  • 46
    • 1342325392 scopus 로고    scopus 로고
    • A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex
    • Kataoka, N. and Dreyfuss, G. (2004) A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex. J. Biol. Chem., 279, 7009-7013.
    • (2004) J. Biol. Chem. , vol.279 , pp. 7009-7013
    • Kataoka, N.1    Dreyfuss, G.2
  • 47
    • 0035823150 scopus 로고    scopus 로고
    • Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex
    • Kim, V.N., Kataoka, N. and Dreyfuss, G. (2001) Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex. Science, 293, 1832-1836.
    • (2001) Science , vol.293 , pp. 1832-1836
    • Kim, V.N.1    Kataoka, N.2    Dreyfuss, G.3
  • 49
    • 84919843479 scopus 로고    scopus 로고
    • 3' UTR length and messenger ribonucleoprotein composition determine endocleavage efficiencies at termination codons
    • Boehm, V., Haberman, N., Ottens, F., Ule, J. and Gehring, N.H. (2014) 3' UTR length and messenger ribonucleoprotein composition determine endocleavage efficiencies at termination codons. Cell Rep., 9, 555-568.
    • (2014) Cell Rep. , vol.9 , pp. 555-568
    • Boehm, V.1    Haberman, N.2    Ottens, F.3    Ule, J.4    Gehring, N.H.5
  • 51
    • 84884692094 scopus 로고    scopus 로고
    • Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways
    • Metze, S., Herzog, V.A., Ruepp, M.D. and Muhlemann, O. (2013) Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways. RNA, 19, 1432-1448.
    • (2013) RNA , vol.19 , pp. 1432-1448
    • Metze, S.1    Herzog, V.A.2    Ruepp, M.D.3    Muhlemann, O.4
  • 52
    • 45449118785 scopus 로고    scopus 로고
    • Recognition of nonsense mRNA: Towards a unified model
    • Muhlemann, O. (2008) Recognition of nonsense mRNA: towards a unified model. Biochem. Soc. Trans., 36, 497-501.
    • (2008) Biochem. Soc. Trans. , vol.36 , pp. 497-501
    • Muhlemann, O.1
  • 53
    • 43249084802 scopus 로고    scopus 로고
    • A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay
    • Singh, G., Rebbapragada, I. and Lykke-Andersen, J. (2008) A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay. PLoS Biol. 6, e111.
    • (2008) PLoS Biol , vol.6 , pp. e111
    • Singh, G.1    Rebbapragada, I.2    Lykke-Andersen, J.3


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