-
1
-
-
33744994837
-
EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 30 UTR length
-
Bühler, M., Steiner, S., Mohn, F., Paillusson, A., and Mühlemann, O. (2006). EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 30 UTR length. Nat. Struct. Mol. Biol. 13, 462-464.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 462-464
-
-
Bühler, M.1
Steiner, S.2
Mohn, F.3
Paillusson, A.4
Mühlemann, O.5
-
2
-
-
84906218594
-
Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6
-
Chakrabarti, S., Bonneau, F., Schüssler, S., Eppinger, E., and Conti, E. (2014). Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6. Nucleic Acids Res. 42, 9447-9460.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 9447-9460
-
-
Chakrabarti, S.1
Bonneau, F.2
Schüssler, S.3
Eppinger, E.4
Conti, E.5
-
3
-
-
67650330563
-
A UPF3-mediated regulatory switch that maintains RNA surveillance
-
Chan, W.K., Bhalla, A.D., Le Hir, H., Nguyen, L.S., Huang, L., Gécz, J., and Wilkinson, M.F. (2009). A UPF3-mediated regulatory switch that maintains RNA surveillance. Nat. Struct. Mol. Biol. 16, 747-753.
-
(2009)
Nat. Struct. Mol. Biol
, vol.16
, pp. 747-753
-
-
Chan, W.K.1
Bhalla, A.D.2
Le Hir, H.3
Nguyen, L.S.4
Huang, L.5
Gécz, J.6
Wilkinson, M.F.7
-
4
-
-
34247197937
-
The nonsense-mediated decay RNA surveillance pathway
-
Chang, Y.F., Imam, J.S., and Wilkinson, M.F. (2007). The nonsense-mediated decay RNA surveillance pathway. Annu. Rev. Biochem. 76, 51-74.
-
(2007)
Annu. Rev. Biochem
, vol.76
, pp. 51-74
-
-
Chang, Y.F.1
Imam, J.S.2
Wilkinson, M.F.3
-
5
-
-
68249138707
-
Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2
-
Clerici, M., Mourão, A., Gutsche, I., Gehring, N.H., Hentze, M.W., Kulozik, A., Kadlec, J., Sattler, M., and Cusack, S. (2009). Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2. EMBO J. 28, 2293-2306.
-
(2009)
EMBO J
, vol.28
, pp. 2293-2306
-
-
Clerici, M.1
Mourão, A.2
Gutsche, I.3
Gehring, N.H.4
Hentze, M.W.5
Kulozik, A.6
Kadlec, J.7
Sattler, M.8
Cusack, S.9
-
6
-
-
84895824865
-
Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2
-
Clerici, M., Deniaud, A., Boehm, V., Gehring, N.H., Schaffitzel, C., and Cusack, S. (2014). Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2. Nucleic Acids Res. 42, 2673-2686.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 2673-2686
-
-
Clerici, M.1
Deniaud, A.2
Boehm, V.3
Gehring, N.H.4
Schaffitzel, C.5
Cusack, S.6
-
7
-
-
0033082394
-
RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer
-
Culbertson, M.R. (1999). RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer. Trends Genet. 15, 74-80.
-
(1999)
Trends Genet
, vol.15
, pp. 74-80
-
-
Culbertson, M.R.1
-
8
-
-
43249093760
-
Posttranscriptional gene regulation by spatial rearrangement of the 30 untranslated region
-
Eberle, A.B., Stalder, L., Mathys, H., Orozco, R.Z., and Mühlemann, O. (2008). Posttranscriptional gene regulation by spatial rearrangement of the 30 untranslated region. PLoS Biol. 6, e92.
-
(2008)
PLoS Biol
, vol.6
-
-
Eberle, A.B.1
Stalder, L.2
Mathys, H.3
Orozco, R.Z.4
Mühlemann, O.5
-
9
-
-
58149265041
-
SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells
-
Eberle, A.B., Lykke-Andersen, S., Mühlemann, O., and Jensen, T.H. (2009). SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells. Nat. Struct. Mol. Biol. 16, 49-55.
-
(2009)
Nat. Struct. Mol. Biol
, vol.16
, pp. 49-55
-
-
Eberle, A.B.1
Lykke-Andersen, S.2
Mühlemann, O.3
Jensen, T.H.4
-
10
-
-
84907189359
-
The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay
-
Fatscher, T., Boehm, V., Weiche, B., and Gehring, N.H. (2014). The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay. RNA 20, 1579-1592.
-
(2014)
RNA
, vol.20
, pp. 1579-1592
-
-
Fatscher, T.1
Boehm, V.2
Weiche, B.3
Gehring, N.H.4
-
11
-
-
13944259434
-
SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway
-
Fukuhara, N., Ebert, J., Unterholzner, L., Lindner, D., Izaurralde, E., and Conti, E. (2005). SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. Mol. Cell 17, 537-547.
-
(2005)
Mol. Cell
, vol.17
, pp. 537-547
-
-
Fukuhara, N.1
Ebert, J.2
Unterholzner, L.3
Lindner, D.4
Izaurralde, E.5
Conti, E.6
-
12
-
-
2942595765
-
Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila
-
Gatfield, D., and Izaurralde, E. (2004). Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila. Nature 429, 575-578.
-
(2004)
Nature
, vol.429
, pp. 575-578
-
-
Gatfield, D.1
Izaurralde, E.2
-
13
-
-
0038814325
-
Y14 and hUpf3b form an NMD-activating complex
-
Gehring, N.H., Neu-Yilik, G., Schell, T., Hentze, M.W., and Kulozik, A.E. (2003). Y14 and hUpf3b form an NMD-activating complex. Mol. Cell 11, 939-949.
-
(2003)
Mol. Cell
, vol.11
, pp. 939-949
-
-
Gehring, N.H.1
Neu-Yilik, G.2
Schell, T.3
Hentze, M.W.4
Kulozik, A.E.5
-
14
-
-
25844512736
-
Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements
-
Gehring, N.H., Kunz, J.B., Neu-Yilik, G., Breit, S., Viegas, M.H., Hentze, M.W., and Kulozik, A.E. (2005). Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Mol. Cell 20, 65-75.
-
(2005)
Mol. Cell
, vol.20
, pp. 65-75
-
-
Gehring, N.H.1
Kunz, J.B.2
Neu-Yilik, G.3
Breit, S.4
Viegas, M.H.5
Hentze, M.W.6
Kulozik, A.E.7
-
15
-
-
57749180915
-
Tethering assays to investigate nonsense-mediated mRNA decay activating proteins
-
Gehring, N.H., Hentze, M.W., and Kulozik, A.E. (2008). Tethering assays to investigate nonsense-mediated mRNA decay activating proteins. Methods Enzymol. 448, 467-482.
-
(2008)
Methods Enzymol
, vol.448
, pp. 467-482
-
-
Gehring, N.H.1
Hentze, M.W.2
Kulozik, A.E.3
-
16
-
-
65249119729
-
Disassembly of exon junction complexes by PYM
-
Gehring, N.H., Lamprinaki, S., Kulozik, A.E., and Hentze, M.W. (2009). Disassembly of exon junction complexes by PYM. Cell 137, 536-548.
-
(2009)
Cell
, vol.137
, pp. 536-548
-
-
Gehring, N.H.1
Lamprinaki, S.2
Kulozik, A.E.3
Hentze, M.W.4
-
17
-
-
33750490399
-
Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex
-
Glavan, F., Behm-Ansmant, I., Izaurralde, E., and Conti, E. (2006). Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. EMBO J. 25, 5117-5125.
-
(2006)
EMBO J
, vol.25
, pp. 5117-5125
-
-
Glavan, F.1
Behm-Ansmant, I.2
Izaurralde, E.3
Conti, E.4
-
18
-
-
3542995089
-
Nonsense-mediated decay approaches the clinic
-
Holbrook, J.A., Neu-Yilik, G., Hentze, M.W., and Kulozik, A.E. (2004). Nonsense-mediated decay approaches the clinic. Nat. Genet. 36, 801-808.
-
(2004)
Nat. Genet
, vol.36
, pp. 801-808
-
-
Holbrook, J.A.1
Neu-Yilik, G.2
Hentze, M.W.3
Kulozik, A.E.4
-
19
-
-
57049126216
-
SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan
-
Huntzinger, E., Kashima, I., Fauser, M., Saulière, J., and Izaurralde, E. (2008). SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. RNA 14, 2609-2617.
-
(2008)
RNA
, vol.14
, pp. 2609-2617
-
-
Huntzinger, E.1
Kashima, I.2
Fauser, M.3
Saulière, J.4
Izaurralde, E.5
-
20
-
-
1842473091
-
The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
-
Kadlec, J., Izaurralde, E., and Cusack, S. (2004). The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Nat. Struct. Mol. Biol. 11, 330-337.
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 330-337
-
-
Kadlec, J.1
Izaurralde, E.2
Cusack, S.3
-
21
-
-
32044435368
-
Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay
-
Kashima, I., Yamashita, A., Izumi, N., Kataoka, N., Morishita, R., Hoshino, S., Ohno, M., Dreyfuss, G., and Ohno, S. (2006). Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes Dev. 20, 355-367.
-
(2006)
Genes Dev
, vol.20
, pp. 355-367
-
-
Kashima, I.1
Yamashita, A.2
Izumi, N.3
Kataoka, N.4
Morishita, R.5
Hoshino, S.6
Ohno, M.7
Dreyfuss, G.8
Ohno, S.9
-
22
-
-
78049447110
-
SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay
-
Kashima, I., Jonas, S., Jayachandran, U., Buchwald, G., Conti, E., Lupas, A.N., and Izaurralde, E. (2010). SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes Dev. 24, 2440-2450.
-
(2010)
Genes Dev
, vol.24
, pp. 2440-2450
-
-
Kashima, I.1
Jonas, S.2
Jayachandran, U.3
Buchwald, G.4
Conti, E.5
Lupas, A.N.6
Izaurralde, E.7
-
23
-
-
84867850145
-
NMD: a multifaceted response to premature translational termination
-
Kervestin, S., and Jacobson, A. (2012). NMD: a multifaceted response to premature translational termination. Nat. Rev. Mol. Cell Biol. 13, 700-712.
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 700-712
-
-
Kervestin, S.1
Jacobson, A.2
-
24
-
-
84885356907
-
The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2
-
Loh, B., Jonas, S., and Izaurralde, E. (2013). The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2. Genes Dev. 27, 2125-2138.
-
(2013)
Genes Dev
, vol.27
, pp. 2125-2138
-
-
Loh, B.1
Jonas, S.2
Izaurralde, E.3
-
25
-
-
74549134095
-
How and where are nonsense mRNAs degraded in mammalian cells?
-
Mühlemann, O., and Lykke-Andersen, J. (2010). How and where are nonsense mRNAs degraded in mammalian cells? RNA Biol. 7, 28-32.
-
(2010)
RNA Biol
, vol.7
, pp. 28-32
-
-
Mühlemann, O.1
Lykke-Andersen, J.2
-
26
-
-
0035254681
-
Splicing and 30 end formation in the definition of nonsense-mediated decay-competent human beta-globin mRNPs
-
Neu-Yilik, G., Gehring, N.H., Thermann, R., Frede, U., Hentze, M.W., and Kulozik, A.E. (2001). Splicing and 30 end formation in the definition of nonsense-mediated decay-competent human beta-globin mRNPs. EMBO J. 20, 532-540.
-
(2001)
EMBO J
, vol.20
, pp. 532-540
-
-
Neu-Yilik, G.1
Gehring, N.H.2
Thermann, R.3
Frede, U.4
Hentze, M.W.5
Kulozik, A.E.6
-
27
-
-
77949904260
-
Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors
-
Nicholson, P., Yepiskoposyan, H., Metze, S., Zamudio Orozco, R., Kleinschmidt, N., and Mühlemann, O. (2010). Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors. Cell. Mol. Life Sci. 67, 677-700.
-
(2010)
Cell. Mol. Life Sci
, vol.67
, pp. 677-700
-
-
Nicholson, P.1
Yepiskoposyan, H.2
Metze, S.3
Zamudio Orozco, R.4
Kleinschmidt, N.5
Mühlemann, O.6
-
28
-
-
84906239869
-
A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD
-
Nicholson, P., Josi, C., Kurosawa, H., Yamashita, A., and Mühlemann, O. (2014). A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD. Nucleic Acids Res. 42, 9217-9235.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 9217-9235
-
-
Nicholson, P.1
Josi, C.2
Kurosawa, H.3
Yamashita, A.4
Mühlemann, O.5
-
29
-
-
0942268832
-
Splicing enhances translation in mammalian cells: an additional function of the exon junction complex
-
Nott, A., Le Hir, H., and Moore, M.J. (2004). Splicing enhances translation in mammalian cells: an additional function of the exon junction complex. Genes Dev. 18, 210-222.
-
(2004)
Genes Dev
, vol.18
, pp. 210-222
-
-
Nott, A.1
Le Hir, H.2
Moore, M.J.3
-
30
-
-
84856858152
-
N-and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD
-
Okada-Katsuhata, Y., Yamashita, A., Kutsuzawa, K., Izumi, N., Hirahara, F., and Ohno, S. (2012). N-and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD. Nucleic Acids Res. 40, 1251-1266.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 1251-1266
-
-
Okada-Katsuhata, Y.1
Yamashita, A.2
Kutsuzawa, K.3
Izumi, N.4
Hirahara, F.5
Ohno, S.6
-
31
-
-
43249084802
-
A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay
-
Singh, G., Rebbapragada, I., and Lykke-Andersen, J. (2008). A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay. PLoS Biol. 6, e111.
-
(2008)
PLoS Biol
, vol.6
-
-
Singh, G.1
Rebbapragada, I.2
Lykke-Andersen, J.3
-
32
-
-
84873828345
-
Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability
-
Tani, H., Imamachi, N., Salam, K.A., Mizutani, R., Ijiri, K., Irie, T., Yada, T., Suzuki, Y., and Akimitsu, N. (2012). Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability. RNA Biol. 9, 1370-1379.
-
(2012)
RNA Biol
, vol.9
, pp. 1370-1379
-
-
Tani, H.1
Imamachi, N.2
Salam, K.A.3
Mizutani, R.4
Ijiri, K.5
Irie, T.6
Yada, T.7
Suzuki, Y.8
Akimitsu, N.9
-
33
-
-
0032526946
-
Binary specification of nonsense codons by splicing and cytoplasmic translation
-
Thermann, R., Neu-Yilik, G., Deters, A., Frede, U., Wehr, K., Hagemeier, C., Hentze, M.W., and Kulozik, A.E. (1998). Binary specification of nonsense codons by splicing and cytoplasmic translation. EMBO J. 17, 3484-3494.
-
(1998)
EMBO J
, vol.17
, pp. 3484-3494
-
-
Thermann, R.1
Neu-Yilik, G.2
Deters, A.3
Frede, U.4
Wehr, K.5
Hagemeier, C.6
Hentze, M.W.7
Kulozik, A.E.8
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