메뉴 건너뛰기




Volumn 59, Issue 5, 2016, Pages 933-937

Pleotropic effects of leptin to reverse insulin resistance and diabetic ketoacidosis

Author keywords

Diabetic ketoacidosis; Leptin; Lipodystrophy; Review; Type 1 diabetes

Indexed keywords

INSULIN; LEPTIN;

EID: 84960324641     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-016-3909-4     Document Type: Review
Times cited : (33)

References (23)
  • 1
    • 0036114844 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
    • COI: 1:CAS:528:DC%2BD38XjvFCls7k%3D, PID: 12021250
    • Petersen KF, Oral EA, Dufour S et al (2002) Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest 109:1345–1350
    • (2002) J Clin Invest , vol.109 , pp. 1345-1350
    • Petersen, K.F.1    Oral, E.A.2    Dufour, S.3
  • 2
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • COI: 1:CAS:528:DC%2BD3cXkvFWhu7k%3D, PID: 10903330
    • Shulman GI (2000) Cellular mechanisms of insulin resistance. J Clin Invest 106:171–176
    • (2000) J Clin Invest , vol.106 , pp. 171-176
    • Shulman, G.I.1
  • 3
    • 84918819322 scopus 로고    scopus 로고
    • Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease
    • PID: 25229917
    • Shulman GI (2014) Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease. N Engl J Med 371:1131–1141
    • (2014) N Engl J Med , vol.371 , pp. 1131-1141
    • Shulman, G.I.1
  • 4
    • 0034708580 scopus 로고    scopus 로고
    • Mechanism of insulin resistance in A-ZIP/F-1 fatless mice
    • COI: 1:CAS:528:DC%2BD3cXit1enur8%3D, PID: 10722680
    • Kim JK, Gavrilova O, Chen Y, Reitman ML, Shulman GI (2000) Mechanism of insulin resistance in A-ZIP/F-1 fatless mice. J Biol Chem 275:8456–8460
    • (2000) J Biol Chem , vol.275 , pp. 8456-8460
    • Kim, J.K.1    Gavrilova, O.2    Chen, Y.3    Reitman, M.L.4    Shulman, G.I.5
  • 5
    • 84883483789 scopus 로고    scopus 로고
    • Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin
    • COI: 1:CAS:528:DC%2BC3sXhsVSht7bM, PID: 24011077
    • Fujikawa T, Berglund ED, Patel VR et al (2013) Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin. Cell Metab 18:431–444
    • (2013) Cell Metab , vol.18 , pp. 431-444
    • Fujikawa, T.1    Berglund, E.D.2    Patel, V.R.3
  • 6
    • 84883172997 scopus 로고    scopus 로고
    • Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia
    • COI: 1:CAS:528:DC%2BC3sXhsVegs7bL, PID: 23782941
    • Meek TH, Matsen ME, Dorfman MD et al (2013) Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia. Endocrinology 154:3067–3076
    • (2013) Endocrinology , vol.154 , pp. 3067-3076
    • Meek, T.H.1    Matsen, M.E.2    Dorfman, M.D.3
  • 7
    • 78049271280 scopus 로고    scopus 로고
    • Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice
    • COI: 1:CAS:528:DC%2BC3cXht12ltrnJ, PID: 20855609
    • Fujikawa T, Chuang JC, Sakata I, Ramadori G, Coppari R (2010) Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice. Proc Natl Acad Sci U S A 107:17391–17396
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 17391-17396
    • Fujikawa, T.1    Chuang, J.C.2    Sakata, I.3    Ramadori, G.4    Coppari, R.5
  • 8
    • 0033037727 scopus 로고    scopus 로고
    • Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat
    • COI: 1:CAS:528:DyaK1MXktFanu78%3D, PID: 10389859
    • Chinookoswong N, Wang JL, Shi ZQ (1999) Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat. Diabetes 48:1487–1492
    • (1999) Diabetes , vol.48 , pp. 1487-1492
    • Chinookoswong, N.1    Wang, J.L.2    Shi, Z.Q.3
  • 9
    • 77950373635 scopus 로고    scopus 로고
    • Leptin therapy in insulin-deficient type I diabetes
    • COI: 1:CAS:528:DC%2BC3cXjvFaqs7c%3D, PID: 20194735
    • Wang MY, Chen L, Clark GO et al (2010) Leptin therapy in insulin-deficient type I diabetes. Proc Natl Acad Sci U S A 107:4813–4819
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 4813-4819
    • Wang, M.Y.1    Chen, L.2    Clark, G.O.3
  • 10
    • 52949140814 scopus 로고    scopus 로고
    • Making insulin-deficient type 1 diabetic rodents thrive without insulin
    • COI: 1:CAS:528:DC%2BD1cXhtFKiurjM, PID: 18779578
    • Yu X, Park BH, Wang MY, Wang ZV, Unger RH (2008) Making insulin-deficient type 1 diabetic rodents thrive without insulin. Proc Natl Acad Sci U S A 105:14070–14075
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14070-14075
    • Yu, X.1    Park, B.H.2    Wang, M.Y.3    Wang, Z.V.4    Unger, R.H.5
  • 12
    • 84924061396 scopus 로고    scopus 로고
    • Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes
    • COI: 1:CAS:528:DC%2BC2cXitFOrtb%2FF, PID: 25737949
    • Kim GH, Szabo A, King EM, Ayala J, Ayala JE, Altarejos JY (2015) Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes. Mol Metab 4:227–236
    • (2015) Mol Metab , vol.4 , pp. 227-236
    • Kim, G.H.1    Szabo, A.2    King, E.M.3    Ayala, J.4    Ayala, J.E.5    Altarejos, J.Y.6
  • 13
    • 84908032144 scopus 로고    scopus 로고
    • Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes
    • PID: 25137027
    • Meek TH, Matsen ME, Damian V, Cubelo A, Chua SC Jr, Morton GJ (2014) Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes. Endocrinology 155:4157–4167
    • (2014) Endocrinology , vol.155 , pp. 4157-4167
    • Meek, T.H.1    Matsen, M.E.2    Damian, V.3    Cubelo, A.4    Chua, S.C.5    Morton, G.J.6
  • 14
    • 84928790920 scopus 로고    scopus 로고
    • FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis
    • COI: 1:CAS:528:DC%2BC2MXhtF2it73M, PID: 25916467
    • Perry RJ, Lee S, Ma L, Zhang D, Schlessinger J, Shulman GI (2015) FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis. Nat Commun 6:6980
    • (2015) Nat Commun , vol.6 , pp. 6980
    • Perry, R.J.1    Lee, S.2    Ma, L.3    Zhang, D.4    Schlessinger, J.5    Shulman, G.I.6
  • 15
    • 84904000735 scopus 로고    scopus 로고
    • Leptin reverses diabetes by suppression of the hypothalamic–pituitary–adrenal axis
    • COI: 1:CAS:528:DC%2BC2cXpslGis70%3D, PID: 24929951
    • Perry RJ, Zhang XM, Zhang D et al (2014) Leptin reverses diabetes by suppression of the hypothalamic–pituitary–adrenal axis. Nat Med 20:759–763
    • (2014) Nat Med , vol.20 , pp. 759-763
    • Perry, R.J.1    Zhang, X.M.2    Zhang, D.3
  • 16
    • 84904043029 scopus 로고    scopus 로고
    • Regulatory role of leptin in glucose and lipid metabolism in skeletal muscle
    • PID: 23565491
    • Minokoshi Y, Toda C, Okamoto S (2012) Regulatory role of leptin in glucose and lipid metabolism in skeletal muscle. Indian J Endocrinol Metab 16:S562–S568
    • (2012) Indian J Endocrinol Metab , vol.16 , pp. S562-S568
    • Minokoshi, Y.1    Toda, C.2    Okamoto, S.3
  • 17
    • 84883689591 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase in the ventromedial hypothalamus mediates leptin-induced glucose uptake in red-type skeletal muscle
    • COI: 1:CAS:528:DC%2BC3sXhtFWjsLjO, PID: 23530005
    • Toda C, Shiuchi T, Kageyama H et al (2013) Extracellular signal-regulated kinase in the ventromedial hypothalamus mediates leptin-induced glucose uptake in red-type skeletal muscle. Diabetes 62:2295–2307
    • (2013) Diabetes , vol.62 , pp. 2295-2307
    • Toda, C.1    Shiuchi, T.2    Kageyama, H.3
  • 19
    • 0037148928 scopus 로고    scopus 로고
    • Leptin-replacement therapy for lipodystrophy
    • COI: 1:CAS:528:DC%2BD38XhsFKqu7c%3D, PID: 11856796
    • Oral EA, Simha V, Ruiz E et al (2002) Leptin-replacement therapy for lipodystrophy. N Engl J Med 346:570–578
    • (2002) N Engl J Med , vol.346 , pp. 570-578
    • Oral, E.A.1    Simha, V.2    Ruiz, E.3
  • 20
    • 0036800760 scopus 로고    scopus 로고
    • Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
    • COI: 1:CAS:528:DC%2BD38XotFGlurk%3D, PID: 12393845
    • Farooqi IS, Matarese G, Lord GM et al (2002) Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 110:1093–1103
    • (2002) J Clin Invest , vol.110 , pp. 1093-1103
    • Farooqi, I.S.1    Matarese, G.2    Lord, G.M.3
  • 21
    • 84948843974 scopus 로고    scopus 로고
    • Evidence against hypothalamic-pituitary-adrenal axis suppression in the antidiabetic action of leptin
    • PID: 26529250
    • Morton GJ, Meek TH, Matsen ME, Schwartz MW (2015) Evidence against hypothalamic-pituitary-adrenal axis suppression in the antidiabetic action of leptin. J Clin Invest 125:4587–4591
    • (2015) J Clin Invest , vol.125 , pp. 4587-4591
    • Morton, G.J.1    Meek, T.H.2    Matsen, M.E.3    Schwartz, M.W.4
  • 22
    • 0023275573 scopus 로고
    • Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats
    • COI: 1:CAS:528:DyaL2sXktlOmsrg%3D, PID: 3571496
    • Rossetti L, Smith D, Shulman GI, Papachristou D, DeFronzo RA (1987) Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest 79:1510–1515
    • (1987) J Clin Invest , vol.79 , pp. 1510-1515
    • Rossetti, L.1    Smith, D.2    Shulman, G.I.3    Papachristou, D.4    DeFronzo, R.A.5
  • 23
    • 84922709227 scopus 로고    scopus 로고
    • Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes
    • COI: 1:CAS:528:DC%2BC2MXisVSiu74%3D, PID: 25662011
    • Perry RJ, Camporez JP, Kursawe R et al (2015) Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes. Cell 160:745–758
    • (2015) Cell , vol.160 , pp. 745-758
    • Perry, R.J.1    Camporez, J.P.2    Kursawe, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.