Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia

Endocrinology

Volumn 154, Issue 9, 2013, Pages 3067-3076

  Meek, Thomas H ^a   Matsen, Miles E ^a   Dorfman, Mauricio D ^a   Guyenet, Stephan J ^a   Damian, Vincent ^a   Nguyen, Hong T ^a   Taborsky Jr , Gerald J ^b   Morton, Gregory J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; GLUCOSE; INSULIN; LEPTIN; STEROIDOGENIC FACTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BODY WEIGHT; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DRUG EFFECT; FOOD INTAKE; GENE; GENE DELETION; GENE EXPRESSION; GLUCAGON BLOOD LEVEL; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; HYPERGLYCEMIA; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; LEPTIN RECEPTOR GENE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STREPTOZOCIN DIABETES;

ANIMALS; DIABETES MELLITUS, TYPE 1; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCONEOGENESIS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INFUSIONS, INTRAVENTRICULAR; INJECTIONS, INTRAVENTRICULAR; LEPTIN; LIVER; MALE; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; RATS; RATS, WISTAR; RECEPTORS, LEPTIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

EID: 84883172997     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1328     Document Type: Article

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