-
1
-
-
81355123438
-
Evolution of microRNA diversity and regulation in animals
-
Berezikov E. Evolution of microRNA diversity and regulation in animals. Nat. Rev. Genet. 2011, 12(12):846-860.
-
(2011)
Nat. Rev. Genet.
, vol.12
, Issue.12
, pp. 846-860
-
-
Berezikov, E.1
-
2
-
-
77955362051
-
Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats
-
Cheng M.F., Chen L.J., Cheng J.T. Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats. J. Biomed. Biotechnol. 2010, 2010:513853.
-
(2010)
J. Biomed. Biotechnol.
, vol.2010
, pp. 513853
-
-
Cheng, M.F.1
Chen, L.J.2
Cheng, J.T.3
-
3
-
-
79953138206
-
Klotho inhibits transforming growth factor-β1 (TGF-β1) signaling and suppresses renal fibrosis and Cancer metastasis in mice
-
Doi S., Zou Y., Toqao O., et al. Klotho inhibits transforming growth factor-β1 (TGF-β1) signaling and suppresses renal fibrosis and Cancer metastasis in mice. J. Biol. Chem. 2011, 286(10):8655-8665.
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.10
, pp. 8655-8665
-
-
Doi, S.1
Zou, Y.2
Toqao, O.3
-
4
-
-
34247483919
-
An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling
-
Fukao T., Fukuda Y., Kiga K., et al. An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling. Cell 2007, 129:617-631.
-
(2007)
Cell
, vol.129
, pp. 617-631
-
-
Fukao, T.1
Fukuda, Y.2
Kiga, K.3
-
5
-
-
84859715394
-
Molecular mechanism underlying persistent induction of LCN2 by lipopolysaccharide in kidney fibroblasts
-
Glaros T., Fu Y., Xing J.H., et al. Molecular mechanism underlying persistent induction of LCN2 by lipopolysaccharide in kidney fibroblasts. Plos One 2012, 7(4):1-8.
-
(2012)
Plos One
, vol.7
, Issue.4
, pp. 1-8
-
-
Glaros, T.1
Fu, Y.2
Xing, J.H.3
-
6
-
-
84860573125
-
Renal neutrophil gelatinase associated lipocalin expression in lipopolysaccharide-induced acute kidney injury in the rat
-
Han M., Li Y., Liu M., et al. Renal neutrophil gelatinase associated lipocalin expression in lipopolysaccharide-induced acute kidney injury in the rat. BMC Nephrol. 2012, 13:25.
-
(2012)
BMC Nephrol.
, vol.13
, pp. 25
-
-
Han, M.1
Li, Y.2
Liu, M.3
-
7
-
-
84899082767
-
Up-regulated miR-199a-5p in gastric cancer functions as an oncogene and targets klotho
-
He Xu-Jun, Ma Ying-Yu, Yu Sheng, et al. Up-regulated miR-199a-5p in gastric cancer functions as an oncogene and targets klotho. MC Cancer 2014, 14:218.
-
(2014)
MC Cancer
, vol.14
, pp. 218
-
-
He, X.-J.1
Ma, Y.-Y.2
Yu, S.3
-
8
-
-
78649642147
-
Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective
-
Hu M.C., Shi M., Zhang J.N., et al. Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective. Kidney Int. 2010, 78:1240-1251.
-
(2010)
Kidney Int.
, vol.78
, pp. 1240-1251
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.N.3
-
9
-
-
84901024350
-
Klotho attenuates high glucose-induced fibronectin and cell hypertrophy via the ERK1/2-p38 kinase signaling pathway in renal interstitial fibroblasts
-
Huang Jau-Shyang, Chuang Chao-Tang, Liu Mei-Hsin, et al. Klotho attenuates high glucose-induced fibronectin and cell hypertrophy via the ERK1/2-p38 kinase signaling pathway in renal interstitial fibroblasts. Mol. Cell. Endocrinol. 2014, 390:45-53.
-
(2014)
Mol. Cell. Endocrinol.
, vol.390
, pp. 45-53
-
-
Huang, J.-S.1
Chuang, C.-T.2
Liu, M.-H.3
-
10
-
-
84867708435
-
Hyperglycemia induced toll like receptor 4 expression and activity in Mouse Mesangia cells: relevance to diabetic ephropathy
-
Kaur H., Chien A., Jiala I., et al. Hyperglycemia induced toll like receptor 4 expression and activity in Mouse Mesangia cells: relevance to diabetic ephropathy. Am. J. Physiol. Ren. Physiol. 2012, 303(8):F1145-F1150.
-
(2012)
Am. J. Physiol. Ren. Physiol.
, vol.303
, Issue.8
, pp. F1145-F1150
-
-
Kaur, H.1
Chien, A.2
Jiala, I.3
-
11
-
-
0030724491
-
Mutation of the mouse Klotho gene leads to a syndrome resembling ageing
-
Kuro-o M., Matsumura Y., Aizawa H., et al. Mutation of the mouse Klotho gene leads to a syndrome resembling ageing. Nature 1997, 390(6655):45-51.
-
(1997)
Nature
, vol.390
, Issue.6655
, pp. 45-51
-
-
Kuro-o, M.1
Matsumura, Y.2
Aizawa, H.3
-
12
-
-
24944481544
-
Suppression of aging in mice by the hormone Klotho
-
Kurosu H., Yamamoto M., Clark J.D., et al. Suppression of aging in mice by the hormone Klotho. Science 2005, 309(5742):1829-1833.
-
(2005)
Science
, vol.309
, Issue.5742
, pp. 1829-1833
-
-
Kurosu, H.1
Yamamoto, M.2
Clark, J.D.3
-
13
-
-
84899508204
-
Down-regulation of miR-34a alleviates mesangial proliferation in vitro and glomerular hypertrophy in early diabetic nephropathy mice by targeting GAS1
-
Le Z., Siyi H., Shaodong G., et al. Down-regulation of miR-34a alleviates mesangial proliferation in vitro and glomerular hypertrophy in early diabetic nephropathy mice by targeting GAS1. J. Diabetes Complicat. 2014, 28(3):259-264.
-
(2014)
J. Diabetes Complicat.
, vol.28
, Issue.3
, pp. 259-264
-
-
Le, Z.1
Siyi, H.2
Shaodong, G.3
-
14
-
-
84905384708
-
Soluble a-klotho as a Novel biomarker in the early stage of nephropathy in patients with type 2 diabetes
-
Lee E.Y., Kim S.S., Lee J.-S., et al. Soluble a-klotho as a Novel biomarker in the early stage of nephropathy in patients with type 2 diabetes. PLoS ONE 2014, 9(8):e102984.
-
(2014)
PLoS ONE
, vol.9
, Issue.8
-
-
Lee, E.Y.1
Kim, S.S.2
Lee, J.-S.3
-
15
-
-
84928013188
-
MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy
-
Li X., Du N., Zhang Q., et al. MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy. Cell Death Dis. 2014, 5(10):e1479.
-
(2014)
Cell Death Dis.
, vol.5
, Issue.10
-
-
Li, X.1
Du, N.2
Zhang, Q.3
-
16
-
-
78651441827
-
Thyroid hormone potentiates insulin signaling and attenuates hyperglycemia and insulin resistance in a mouse model of type 2 diabetes
-
Lin Y., Sun Z. Thyroid hormone potentiates insulin signaling and attenuates hyperglycemia and insulin resistance in a mouse model of type 2 diabetes. Br. J. Pharmacol. 2011, 162(3):597-610.
-
(2011)
Br. J. Pharmacol.
, vol.162
, Issue.3
, pp. 597-610
-
-
Lin, Y.1
Sun, Z.2
-
17
-
-
84862922902
-
Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy
-
Lin M., Yiu W.H., Wu H.J., et al. Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy. J. Am. Soc. Nephrol. 2012, 23(1):86-102.
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, Issue.1
, pp. 86-102
-
-
Lin, M.1
Yiu, W.H.2
Wu, H.J.3
-
18
-
-
84874779817
-
MiR-199a-5p is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting Caveolin-1
-
Lino Cardenas Christian Lacks, Henaoui Imène Sarah, Courcot Elisabeth, et al. miR-199a-5p is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting Caveolin-1. PLoS Genet. 2013, 9(2):e1003291.
-
(2013)
PLoS Genet.
, vol.9
, Issue.2
-
-
Lino Cardenas, C.L.1
Henaoui Imène, Sarah2
Courcot, E.3
-
19
-
-
84894559925
-
Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activatedretinal microglia cells
-
Liu Guo-Dan, Zhang Hong, Wang Lin, et al. Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activatedretinal microglia cells. Int. J. Ophthalmol. 2013, 6(3):280-285.
-
(2013)
Int. J. Ophthalmol.
, vol.6
, Issue.3
, pp. 280-285
-
-
Liu, G.-D.1
Zhang, H.2
Wang, L.3
-
20
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta DeltaC (T)) method
-
Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta DeltaC (T)) method. Methods 2001, 25(4):402-408.
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
21
-
-
84891043328
-
Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion
-
Locke J.M., da SX G., Dawe H.R., et al. Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion. Diabetologia 2014, 57(1):122-128.
-
(2014)
Diabetologia
, vol.57
, Issue.1
, pp. 122-128
-
-
Locke, J.M.1
da SX, G.2
Dawe, H.R.3
-
22
-
-
84911369878
-
Alpha lipoic acid modulated high glucose-induced rat mesangial cell dysfunction via mTOR/p70S6K/4E-BP1 pathway
-
Lv C., Wu C., Zhou Y.H., Shao Y., Wang G., Wang Q.Y. Alpha lipoic acid modulated high glucose-induced rat mesangial cell dysfunction via mTOR/p70S6K/4E-BP1 pathway. Int. J. Endocrinol. 2014, 2014:658589.
-
(2014)
Int. J. Endocrinol.
, vol.2014
, pp. 658589
-
-
Lv, C.1
Wu, C.2
Zhou, Y.H.3
Shao, Y.4
Wang, G.5
Wang, Q.Y.6
-
23
-
-
84879618751
-
Transforming growth factor-β1 selectively inhibits hepatocyte growth factor expression via a micro-RNA-199-dependent posttranscriptional mechanism
-
Mungunsukh Ognoon, Day Regina M. Transforming growth factor-β1 selectively inhibits hepatocyte growth factor expression via a micro-RNA-199-dependent posttranscriptional mechanism. Mol. Biol. Cell 2013, 24(13):2088-2097.
-
(2013)
Mol. Biol. Cell
, vol.24
, Issue.13
, pp. 2088-2097
-
-
Mungunsukh, O.1
Day, R.M.2
-
24
-
-
84905715174
-
Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function
-
Nunemaker C.S., Chung H.G., Verrilli G.M., et al. Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function. J. Endocrinol. 2014, 222(2):267-276.
-
(2014)
J. Endocrinol.
, vol.222
, Issue.2
, pp. 267-276
-
-
Nunemaker, C.S.1
Chung, H.G.2
Verrilli, G.M.3
-
25
-
-
57849131142
-
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
-
Suchankova G., Nelson L.E., Gerhart-Hines Z., Kelly M., Gauthier M.S., Saha A.K., Ido Y., Puigserver P., Ruderman N.B. Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells. Biochem. Biophys. Res. Commun. 2009, 378:836-841.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.378
, pp. 836-841
-
-
Suchankova, G.1
Nelson, L.E.2
Gerhart-Hines, Z.3
Kelly, M.4
Gauthier, M.S.5
Saha, A.K.6
Ido, Y.7
Puigserver, P.8
Ruderman, N.B.9
-
26
-
-
70349149467
-
Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes
-
Tarabra E., Giunti S., Barutta F., et al. Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes. Diabetes 2009, 58(9):2109-2118.
-
(2009)
Diabetes
, vol.58
, Issue.9
, pp. 2109-2118
-
-
Tarabra, E.1
Giunti, S.2
Barutta, F.3
-
27
-
-
84355162040
-
Re-expression of miR-199a suppresses renal cancer cell proliferation and survival by targeting GSK-3beta
-
Tsukigi M., Bilim V., Yuuki K., Ugolkov A., Naito S., Nagaoka A., Kato T., Motoyama T., Tomita Y. Re-expression of miR-199a suppresses renal cancer cell proliferation and survival by targeting GSK-3beta. Cancer Lett. 2012, 315:189-197.
-
(2012)
Cancer Lett.
, vol.315
, pp. 189-197
-
-
Tsukigi, M.1
Bilim, V.2
Yuuki, K.3
Ugolkov, A.4
Naito, S.5
Nagaoka, A.6
Kato, T.7
Motoyama, T.8
Tomita, Y.9
-
28
-
-
84862843347
-
P53-facilitated miR-199a-3p regulates somatic cell reprogramming
-
Wang J., He Q., Han C., et al. p53-facilitated miR-199a-3p regulates somatic cell reprogramming. Stem Cells 2012, 30:1405-1413.
-
(2012)
Stem Cells
, vol.30
, pp. 1405-1413
-
-
Wang, J.1
He, Q.2
Han, C.3
-
29
-
-
84920555876
-
The changes of serum sKlotho and NGAL levels and their correlation in type 2 diabetes mellitus patients with different stages of urinary albumin
-
Wu C., Wang Q.Y., Lv C., et al. The changes of serum sKlotho and NGAL levels and their correlation in type 2 diabetes mellitus patients with different stages of urinary albumin. Diabetes Res. Clin. Pract. 2014, 106(2):343-350.
-
(2014)
Diabetes Res. Clin. Pract.
, vol.106
, Issue.2
, pp. 343-350
-
-
Wu, C.1
Wang, Q.Y.2
Lv, C.3
-
30
-
-
77955272026
-
Establishment of sandwich ELISA for soluble alpha-Klotho measurement: age-dependent change of soluble alpha-Klotho levels in healthy subjects
-
Yamazaki Y., Imura A., Urakawa I., et al. Establishment of sandwich ELISA for soluble alpha-Klotho measurement: age-dependent change of soluble alpha-Klotho levels in healthy subjects. Biochem. Biophys. Res. Commun. 2010, 398(3):513-518.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.398
, Issue.3
, pp. 513-518
-
-
Yamazaki, Y.1
Imura, A.2
Urakawa, I.3
-
31
-
-
9144271181
-
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells
-
Zang M., Zuccollo A., Hou X., Nagata D., Walsh K., Herscovitz H., Brecher P., Ruderman N.B., Cohen R.A. AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. J. Biol. Chem. 2004, 279:47898-47905.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47898-47905
-
-
Zang, M.1
Zuccollo, A.2
Hou, X.3
Nagata, D.4
Walsh, K.5
Herscovitz, H.6
Brecher, P.7
Ruderman, N.B.8
Cohen, R.A.9
-
32
-
-
80052101334
-
Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation
-
Zhao Y., Banerjee S., Dey N., et al. Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation. Diabetes 2011, 60(7):1907-1916.
-
(2011)
Diabetes
, vol.60
, Issue.7
, pp. 1907-1916
-
-
Zhao, Y.1
Banerjee, S.2
Dey, N.3
-
33
-
-
0027452124
-
The extracellular matrix in diabetic nephropathy
-
Ziyadeh E.F. The extracellular matrix in diabetic nephropathy. Am. J. Kidney Dis. 1993, 22:736-744.
-
(1993)
Am. J. Kidney Dis.
, vol.22
, pp. 736-744
-
-
Ziyadeh, E.F.1
|