Down-regulation of miR-34a alleviates mesangial proliferation in vitro and glomerular hypertrophy in early diabetic nephropathy mice by targeting GAS1

Journal of Diabetes and its Complications

Volumn 28, Issue 3, 2014, Pages 259-264

  Zhang, Le ^a   He, Siyi ^a   Guo, Shaodong ^b   Xie, Wei ^a   Xin, Rong ^a   Yu, Hua ^a   Yang, Fan ^a   Qiu, Jing ^a   Zhang, Di ^a   Zhou, Shiwen ^a   Zhang, Kebin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Texas A and M University   (United States)

Author keywords

Diabetic nephropathy; GAS1; Glomerular hypertrophy; miR 34a

Indexed keywords

ANTAGOMIR; CARRIER PROTEINS AND BINDING PROTEINS; DEOXYURIDINE DERIVATIVE; GLUCOSE; GROWTH ARREST SPECIFIC 1; LUCIFERASE; MICRORNA 34A; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; GAS1 PROTEIN, MOUSE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; MICRORNA; MIRN34 MICRORNA, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNTING; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DOWN REGULATION; GENE EXPRESSION; GENE TARGETING; HYPERGLYCEMIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY HYPERTROPHY; LUCIFERASE ASSAY; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL SURVIVAL; COMPLICATION; DIABETIC NEPHROPATHIES; DISEASE MODEL; DRUG EFFECTS; GENETICS; GLOMERULUS; HYPERTROPHY; METABOLISM; MUTANT MOUSE STRAIN; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CELL CYCLE PROTEINS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GLUCOSE; GPI-LINKED PROTEINS; HYPERTROPHY; IN VITRO TECHNIQUES; KIDNEY GLOMERULUS; MALE; MESANGIAL CELLS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICRORNAS;

EID: 84899508204     PISSN: 10568727     EISSN: 1873460X     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2014.01.002     Document Type: Article

References (32)

1. X.Y. Bai, Y. Ma, R. Ding, B. Fu, S. Shi, and X.M. Chen miR-335 and miR-34a Promote renal senescence by suppressing mitochondrial antioxidative enzymes Journal of the American Society of Nephrology: JASN 22 7 2011 1252 1261
2. B.C. Bernardo, X.M. Gao, C.E. Winbanks, E.J. Boey, Y.K. Tham, and H. Kiriazis et al. Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function Proceedings of the National Academy of Sciences of the United States of America 109 43 2012 17615 17620
3. J.R. Cabrera, L. Sanchez-Pulido, A.M. Rojas, A. Valencia, S. Manes, and J.R. Naranjo et al. Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling The Journal of biological chemistry 281 20 2006 14330 14339
4. H. Chen, Y. Sun, R. Dong, S. Yang, C. Pan, and D. Xiang et al. Mir-34a is upregulated during liver regeneration in rats and is associated with the suppression of hepatocyte proliferation PloS one 6 5 2011 e20238
5. Y.Q. Chen, X.X. Wang, X.M. Yao, D.L. Zhang, X.F. Yang, and S.F. Tian et al. Abated microRNA-195 expression protected mesangial cells from apoptosis in early diabetic renal injury in mice Journal of nephrology 25 4 2012 566 576
6. T. Chiyomaru, S. Yamamura, S. Fukuhara, H. Yoshino, T. Kinoshita, and S. Majid et al. Genistein inhibits prostate cancer cell growth by targeting miR-34a and oncogenic HOTAIR PloS one 8 8 2013 e70372
7. F. Conserva, P. Pontrelli, M. Accetturo, and L. Gesualdo The pathogenesis of diabetic nephropathy: Focus on microRNAs and proteomics Journal of nephrology 26 5 2013 811 820
8. Y. Dang, D. Luo, M. Rong, and G. Chen Underexpression of miR-34a in hepatocellular carcinoma and its contribution towards enhancement of proliferating inhibitory effects of agents targeting c-MET PloS one 8 4 2013 e61054
9. P. de Antonellis, C. Medaglia, E. Cusanelli, I. Andolfo, L. Liguori, and G. De Vita et al. MiR-34a targeting of Notch ligand delta-like 1 impairs CD15 +/CD133 + tumor-propagating cells and supports neural differentiation in medulloblastoma PloS one 6 9 2011 e24584
10. A.A. Eid, A. Koubeissi, R. Bou-Mjahed, N.A. Khalil, M. Farah, and R. Maalouf et al. Novel carbocyclic nucleoside analogs suppress glomerular mesangial cells proliferation and matrix protein accumulation through ROS-dependent mechanism in the diabetic milieu Bioorganic & medicinal chemistry letters 23 1 2013 174 178
11. A. Evdokiou, and P.A. Cowled Growth-regulatory activity of the growth arrest-specific gene, GAS1, in NIH3T3 fibroblasts Experimental cell research 240 2 1998 359 367
12. C. Fernandez-Hernando, C.M. Ramirez, L. Goedeke, and Y. Suarez MicroRNAs in metabolic disease Arteriosclerosis, thrombosis, and vascular biology 33 2 2013 178 185
13. S. Gobeil, X. Zhu, C.J. Doillon, and M.R. Green A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene Genes & development 22 21 2008 2932 2940
14. Q. Hou, J. Tang, Z. Wang, C. Wang, X. Chen, and L. Hou et al. Inhibitory effect of microRNA-34a on retinal pigment epithelial cell proliferation and migration Investigative ophthalmology & visual science 54 10 2013 6481 6488
15. H.L. Janssen, H.W. Reesink, E.J. Lawitz, S. Zeuzem, M. Rodriguez-Torres, and K. Patel et al. Treatment of HCV infection by targeting microRNA The New England journal of medicine 368 18 2013 1685 1694
16. Y.S. Kim, M.A. Reddy, L. Lanting, S.G. Adler, and R. Natarajan Differential behavior of mesangial cells derived from 12/15-lipoxygenase knockout mice relative to control mice Kidney international 64 5 2003 1702 1714
17. K.K. Lee, A.K. Leung, M.K. Tang, D.Q. Cai, C. Schneider, and C. Brancolini et al. Functions of the growth arrest specific 1 gene in the development of the mouse embryo Developmental biology 234 1 2001 188 203
18. L. Liu, X. Hu, G.Y. Cai, Y. Lv, L. Zhuo, and J.J. Gao et al. High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling Nephrology, dialysis, transplantation: Official publication of the European Dialysis and Transplant Association - European Renal Association 27 1 2012 90 100
19. V. Nesca, C. Guay, C. Jacovetti, V. Menoud, M.L. Peyot, and D.R. Laybutt et al. Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes Diabetologia 56 10 2013 2203 2212
20. A. Onozaki, S. Midorikawa, H. Sanada, Y. Hayashi, T. Baba, and T. Katoh et al. Rapid change of glucose concentration promotes mesangial cell proliferation via VEGF: Inhibitory effects of thiazolidinedione Biochemical and biophysical research communications 317 1 2004 24 29
21. C.W. Park, H.W. Kim, S.H. Ko, J.H. Lim, G.R. Ryu, and H.W. Chung et al. Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice Journal of the American Society of Nephrology: JASN 18 4 2007 1227 1238
22. M. Stebel, P. Vatta, M.E. Ruaro, G. Del Sal, R.G. Parton, and C. Schneider The growth suppressing gas1 product is a GPI-linked protein FEBS letters 481 2 2000 152 158
23. Y.M. Sun, Y. Su, J. Li, and L.F. Wang Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy Biochemical and biophysical research communications 433 4 2013 359 361
24. C.R. van Roeyen, S. Zok, J. Pruessmeyer, P. Boor, Y. Nagayama, and S. Fleckenstein et al. Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation Kidney international 83 2 2013 251 263
25. H. Wang, X. Zhou, Y. Zhang, H. Zhu, L. Zhao, and L. Fan et al. Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer The FEBS journal 279 19 2012 3652 3664
26. R. Wei, J. Yang, G.Q. Liu, M.J. Gao, W.F. Hou, and L. Zhang et al. Dynamic expression of microRNAs during the differentiation of human embryonic stem cells into insulin-producing cells Gene 518 2 2013 246 255
27. G. Wolf, and F.N. Ziyadeh Molecular mechanisms of diabetic renal hypertrophy Kidney international 56 2 1999 393 405
28. M. Yamakuchi MicroRNA regulation of SIRT1 Frontiers in physiology 3 2012 68
29. N. Zarco, R. Gonzalez-Ramirez, R.O. Gonzalez, and J. Segovia GAS1 induces cell death through an intrinsic apoptotic pathway Apoptosis: An international journal on programmed cell death 17 6 2012 627 635
30. Z. Zhang, X. Luo, S. Ding, J. Chen, T. Chen, and X. Chen et al. MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early diabetic nephropathy FEBS letters 586 1 2012 20 26
31. L. Zhang, S. Pang, B. Deng, L. Qian, J. Chen, and J. Zou et al. High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-kappaB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol The international journal of biochemistry & cell biology 44 4 2012 629 638
32. Z. Zhang, H. Peng, J. Chen, X. Chen, F. Han, and X. Xu et al. MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice FEBS letters 583 12 2009 2009 2014