Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis

Journal of Steroid Biochemistry and Molecular Biology

Volumn 169, Issue , 2017, Pages 69-76

  Nakazawa, Takaya ^a   Miyanoki, Yuta ^a   Urano, Yasuomi ^a   Uehara, Madoka ^a   Saito, Yoshiro ^a   Noguchi, Noriko ^a  

^a DOSHISHA UNIVERSITY   (Japan)

Author keywords

24(S) hydroxycholesterol; Caspase 8; Cell death; Lipid droplet; Tocopherol; Tocotrienol

Indexed keywords

24 HYDROXYCHOLESTEROL; ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; CASPASE 3; CASPASE 8; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL DERIVATIVE; CUMENE HYDROPEROXIDE; FAT DROPLET; LACTATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; RETINOIC ACID; UNCLASSIFIED DRUG; 24-HYDROXYCHOLESTEROL; ANTIOXIDANT; LIPID; TOCOTRIENOL, ALPHA;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NECROPTOSIS; NEUROBLASTOMA CELL; PROTEIN EXPRESSION; SH SY5Y CELL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; METABOLISM; NERVE CELL; TUMOR CELL LINE;

ALPHA-TOCOPHEROL; ANTIOXIDANTS; APOPTOSIS; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; HYDROXYCHOLESTEROLS; LIPIDS; MICROSCOPY, FLUORESCENCE; NEURONS; REACTIVE OXYGEN SPECIES; TOCOTRIENOLS; TRETINOIN; VITAMIN E;

EID: 84960194608     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2016.03.003     Document Type: Article

References (40)

1. [1] Noguchi, N., Saito, Y., Urano, Y., Diverse functions of 24(S)-hydroxycholesterol in the brain. A special issue on oxysterols. Biochem. Biophys. Res. Commun. 446 (2014), 692–696.
2. [2] Noguchi, N., Urano, Y., Takabe, W., Saito, Y., New aspects of 24S-hydroxycholesterol in modulating neuronal cell death. Free Radic. Biol. Med 87 (2015), 366–372.
3. [3] Russell, D.W., Halford, R.W., Ramirez, D.M., Shah, R., Kotti, T., Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain. Ann. Rev. Biochem. 78 (2009), 1017–1040.
4. [4] Bjorkhem, I., Lutjohann, D., Diczfalusy, U., Stahle, L., Ahlborg, G., Wahren, J., Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. J. Lipid Res. 39 (1998), 1594–1600.
5. [5] Urano, Y., Ochiai, S., Noguchi, N., Suppression of amyloid-beta production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking. FASEB J. 27 (2013), 4305–4315.
6. [6] Okabe, A., Urano, Y., Itoh, S., Suda, N., Kotani, R., Nishimura, Y., et al. Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death. Redox Biol. 2 (2014), 28–35.
7. [7] Gamba, P., Guglielmotto, M., Testa, G., Monteleone, D., Zerbinati, C., Gargiulo, S., Biasi, F., Iuliano, L., Giaccone, G., Mauro, A., Poli, G., Tamagno, E., Leonarduzzi, G., Up-regulation of β-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine. Aging Cell 13 (2014), 561–572.
8. [8] Lee, C.Y., Seet, R.C., Huang, S.H., Long, L.H., Halliwell, B., Different patterns of oxidized lipid products in plasma and urine of dengue fever, stroke, and Parkinson's disease patients: cautions in the use of biomarkers of oxidative stress. Antioxid. Redox Signal. 11 (2009), 407–420.
9. [9] Zarrouk, A., Vejux, A., Mackrill, J., O'Callaghan, Y., Hammami, M., O'Brien, N., Lizard, G., Involvement of oxysterols in age-related diseases and ageing processes. Ageing Res. Rev. 18 (2014), 148–162.
10. [10] Kölsch, H., Lütjohann, D., Tulke, A., Björkhem, I., Rao, M.L., The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells. Brain Res. 818 (1999), 171–175.
11. [11] Kölsch, H., Ludwig, M., Lütjohann, D., Rao, M.L., Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta. Neural Transm. 108 (2001), 475–488.
12. [12] Vejux, A., Lizard, G., Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis. Mol. Aspects Med. 30 (2009), 153–170.
13. [13] Nury, T., Zarrouk, A., Mackrill, J.J., Samadi, M., Durand, P., Riedinger, J.M., Doria, M., Vejux, A., Limagne, E., Delmas, D., Prost, M., Moreau, T., Hammami, M., Delage-Mourroux, R., O'Brien, N.M., Lizard, G., Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3). Steroids 99 (2015), 194–203.
14. [14] Yamanaka, K., Saito, Y., Yamamori, T., Urano, Y., Noguchi, N., 24(S)-hydroxycholesterol induces neuronal cell death through necroptosis: a form of programmed necrosis. J. Biol. Chem. 286 (2011), 24666–24673.
15. [15] Degterev, A., Yuan, J., Expansion and evolution of cell death programmes. Nat. Rev. Mol. Cell Biol 9 (2008), 378–390.
16. [16] Yamanaka, K., Urano, Y., Takabe, W., Saito, Y., Noguchi, N., Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA:cholesterol acyltransferase 1. Cell Death Dis., 5, 2014, e990.
17. [17] Jiang, M., Zhu, K., Grenet, J., Lahti, J.M., Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells. Biochim. Biophys. Acta 1783 (2008), 1055–1067.
18. [18] Vandenabeele, P., Galluzzi, L., Vanden Berghe, T., Kroemer, G., Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat. Rev. Mol. Cell Biol. 11 (2010), 700–714.
19. [19] Vo, D.K., Urano, Y., Takabe, W., Saito, Y., Noguchi, N., 24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8. Steroids 99 (2015), 230–237.
20. [20] Sano, M., Ernesto, C., Thomas, R.G., Klauber, M.R., Schafer, K., Grundman, M., Woodbury, P., Growdon, J., Cotman, C.W., Pfeiffer, E., Schneider, L.S., Thai, L.J., A controlled trial of selegiline, aspha-tocopherol, or both as treatment for Alzheimer's desease. The Alzheimer's Disease Cooperative Study. N. Engl. J. Med. 336 (1997), 1216–1222.
21. [21] Morris, M.C., Beckett, L.A., Scherr, P.A., Hebert, L.E., Bennett, D.A., Field, T.S., Evans, D.A., Vitamin E and vitamin C supplement use and risk of incident Alzheimer disease. Alzheimer Dis. Assoc. Disord. 12 (1998), 121–126.
22. [22] Morris, M.C., Evans, D.A., Bienias, J.L., Tangney, C.C., Wilson, R.S., Vitamin E and cognitive decline in older persons. Arch. Neurol. 59 (2002), 1125–1132.
23. [23] Dysken, M.W., Sano, M., Asthana, S., Vertrees, J.E., Pallaki, M., Llorente, M., Love, S., Schellenberg, G.D., McCarten, J.R., Malphurs, J., Prieto, S., Chen, P., Loreck, D.J., Trapp, G., Bakshi, R.S., Mintzer, J.E., Heidebrink, J.L., Vidal-Cardona, A., Arroyo, L.M., Cruz, A.R., Zachariah, S., Kowall, N.W., Chopra, M.P., Craft, S., Thielke, S., Turvey, C.L., Woodman, C., Monnell, K.A., Gordon, K., Tomaska, J., Segal, Y., Peduzzi, P.N., Guarino, P.D., Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial. JAMA 311 (2014), 33–44.
24. [24] Coupland, K.G., Mellick, G.D., Silburn, P.A., Mather, K., Armstrong, N.J., Sachdev, P.S., Brodaty, H., Huang, Y., Halliday, G.M., Hallupp, M., Kim, W.S., Dobson-Stone, C., Kwok, J.B., DNA methylation of the MAPT gene in Parkinson's disease cohorts and modulation by vitamin E in vitro. Mov. Disord. 29 (2014), 1606–1614.
25. [25] Mustacich, D.J., Bruno, R.S., Traber, M.G., Vitamin E. Vitam. Horm. 76 (2007), 1–21.
26. [26] Niki, E., Traber, M.G., A history of vitamin E. Ann. Nutr. Metab. 61 (2012), 207–212.
27. [27] IUPAC-IUB Joint Commissionon Biochemical Nomenclature (JCBN). Nomenclature of tocopherols and related compounds. Recommendations 1981. Eur. J. Biochem. 123, 473-475, (1982).
28. [28] Yoshida, Y., Niki, E., Noguchi, N., Comparative study on the action of tocopherols and tocotrienols as antioxidant: chemical and physical effects. Chem. Phys. Lipid 123 (2003), 63–75.
29. [29] Niki, E., Noguchi, N., Dynamics of antioxidant action of vitamin E. Acc. Chem. Res. 37 (2004), 45–51.
30. [30] Noguchi, N., Hanyu, R., Nonaka, A., Okimoto, Y., Kodama, T., Inhibition of THP-1 cell adhesion to endothelial cells by alpha-tocopherol and alpha-tocotrienol is dependent on intracellular concentration of the antioxidants. Free Radic. Biol. Med. 34 (2003), 1614–1620.
31. [31] Saito, Y., Nishio, K., Yoko Ogawa-Akazawa, Y., Yamanaka, K., Akiko Miyama, A., Yoshida, Y., Noguchi, N., Niki, E., Cytoprotective effects of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: tocopherols and tocotrienols exert similar effects by antioxidant function. Free Radic. Biol. Med. 49 (2010), 1542–1549.
32. [32] Vejux, A., Guyot, S., Montange, T., Riedinger, J.M., Kahn, E., Lizard, G., Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis. J. Nutr. Biochem. 20 (2009), 45–61.
33. [33] Påhlman, S., Ruusala, A.I., Abrahamsson, L., Mattsson, M.E., Esscher, T., Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation. Cell Differ. 14 (1984), 35–144.
34. [34] Izant, J.G., McIntosh, J.R., Microtubule-associated proteins: a monoclonal antibody to MAP2 binds to differentiated neurons. Proc. Natl. Acad. Sci. U. S. A. 77 (1980), 4741–4745.
35. [35] Das, A., Banik, N.L., Ray, S.K., Retinoids induce differentiation and downregulate telomerase activity and N-Myc to increase sensitivity to flavonoids for apoptosis in human malignant neuroblastoma SH-SY5Y cells. Int. J. Oncol. 34 (2009), 757–765.
36. [36] Wada, K., Arita, M., Nakajima, A., Katayama, K., Kudo, C., Kamisaki, Y., Serhan, C.N., Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation. FASEB J. 20 (2006), 1785–1792.
37. [37] Royer, M.C., Lemaire-Ewing, S., Desrumaux, C., Monier, S., Barros, J.P.P., Athias, A., Neel, D., Lagrost, L., 7-Ketochoesterol incorporation int sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for a-tocopherol with consequences on cell death. J. Biol. Chem. 284 (2009), 15826–15834.
38. [38] Takahashi, M., Tsuchiya, J., Niki, E., Urano, S., Action of vitamin E as antioxidant in phospholipid liposomal membranes as studied by spin label technique. J. Nutr. Sci. Vitaminol. 34 (1988), 25–34.
39. [39] Yoshida, Y., Niki, E., Antioxidant action of tocotrienols and tocopherols in solution and membranes: chemical physical effects. Watson, R.R., Preedy, V.R., (eds.) Tocotrienols: Viamin E Beyond Tocopherols, 2008, CRC Press, 109–117.
40. [40] Torkildsen, Ø., Løken-Amsrud, K.I., Wergeland, S., Myhr, K.M., Holmøy, T., Fat-soluble vitamins as disease modulators in multiple sclerosis. Acta Neurol. Scand. Suppl. 196 (2013), 16–23.