-
1
-
-
20444504698
-
The genetic epidemiology of neurodegenerative disease
-
Bertram L, Tanzi RE. The genetic epidemiology of neurodegenerative disease. J Clin Invest 2005;115:1449-1457.
-
(2005)
J Clin Invest
, vol.115
, pp. 1449-1457
-
-
Bertram, L.1
Tanzi, R.E.2
-
2
-
-
71849092190
-
Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
-
Dickson DW, Braak H, Duda JE, et al. Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol 2009;8:1150-1157.
-
(2009)
Lancet Neurol
, vol.8
, pp. 1150-1157
-
-
Dickson, D.W.1
Braak, H.2
Duda, J.E.3
-
3
-
-
84865864065
-
The genetics and neuropathology of Parkinson's disease
-
Houlden H, Singleton AB. The genetics and neuropathology of Parkinson's disease. Acta Neuropathol 2012;124:325-338.
-
(2012)
Acta Neuropathol
, vol.124
, pp. 325-338
-
-
Houlden, H.1
Singleton, A.B.2
-
4
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
Simon-Sanchez J, Schulte C, Bras JM, et al. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet 2009;41:1308-1312.
-
(2009)
Nat Genet
, vol.41
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.M.3
-
5
-
-
77951185469
-
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease
-
Edwards TL, Scott WK, Almonte C, et al. Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Ann Hum Genet 2010;74:97-109.
-
(2010)
Ann Hum Genet
, vol.74
, pp. 97-109
-
-
Edwards, T.L.1
Scott, W.K.2
Almonte, C.3
-
6
-
-
24644502474
-
Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration
-
Pittman AM, Myers AJ, Abou-Sleiman P, et al. Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. J Med Genet 2005;42:837-846.
-
(2005)
J Med Genet
, vol.42
, pp. 837-846
-
-
Pittman, A.M.1
Myers, A.J.2
Abou-Sleiman, P.3
-
7
-
-
1442304904
-
Tau haplotypes regulate transcription and are associated with Parkinson's disease
-
Kwok JB, Teber ET, Loy C, et al. Tau haplotypes regulate transcription and are associated with Parkinson's disease. Ann Neurol 2004;55:329-334.
-
(2004)
Ann Neurol
, vol.55
, pp. 329-334
-
-
Kwok, J.B.1
Teber, E.T.2
Loy, C.3
-
8
-
-
4544297675
-
Linkage disequilibrium and association of MAPT H1 in Parkinson disease
-
Skipper L, Wilkes K, Toft M, et al. Linkage disequilibrium and association of MAPT H1 in Parkinson disease. Am J Hum Genet 2004;75:669-677.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 669-677
-
-
Skipper, L.1
Wilkes, K.2
Toft, M.3
-
9
-
-
84865791125
-
MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
-
Trabzuni D, Wray S, Vandrovcova J, et al. MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies. Hum Mol Genet 2012;21:4094-4103.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4094-4103
-
-
Trabzuni, D.1
Wray, S.2
Vandrovcova, J.3
-
10
-
-
34250335127
-
Functional MAPT haplotypes: bridging the gap between genotype and neuropathology
-
Caffrey TM, Wade-Martins R. Functional MAPT haplotypes: bridging the gap between genotype and neuropathology. Neurobiol Dis 2007;27:1-10.
-
(2007)
Neurobiol Dis
, vol.27
, pp. 1-10
-
-
Caffrey, T.M.1
Wade-Martins, R.2
-
11
-
-
73649107635
-
Epigenetics: molecular mechanisms and implications for disease
-
Handel AE, Ebers GC, Ramagopalan SV. Epigenetics: molecular mechanisms and implications for disease. Trends Mol Med 2010;16:7-16.
-
(2010)
Trends Mol Med
, vol.16
, pp. 7-16
-
-
Handel, A.E.1
Ebers, G.C.2
Ramagopalan, S.V.3
-
12
-
-
0035977865
-
Genomic imprinting and cancer; new paradigms in the genetics of neoplasia
-
Schofield PN, Joyce JA, Lam WK, Grandjean V, Ferguson-Smith A, Reik W, Maher ER. Genomic imprinting and cancer; new paradigms in the genetics of neoplasia. Toxicol Lett 2001;120:151-160.
-
(2001)
Toxicol Lett
, vol.120
, pp. 151-160
-
-
Schofield, P.N.1
Joyce, J.A.2
Lam, W.K.3
Grandjean, V.4
Ferguson-Smith, A.5
Reik, W.6
Maher, E.R.7
-
13
-
-
78149433116
-
Role of epigenetics in Alzheimer's and Parkinson's disease
-
Kwok JBJ. Role of epigenetics in Alzheimer's and Parkinson's disease. Epigenomics 2010;2:671-682.
-
(2010)
Epigenomics
, vol.2
, pp. 671-682
-
-
Kwok, J.B.J.1
-
14
-
-
68949096744
-
Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease [serial online]
-
Mastroeni D, McKee A, Grover A, Rogers J, Coleman PD. Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease [serial online]. PloS One 2009;4:e6617.
-
(2009)
PloS One
, vol.4
, pp. e6617
-
-
Mastroeni, D.1
McKee, A.2
Grover, A.3
Rogers, J.4
Coleman, P.D.5
-
15
-
-
77951842993
-
Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains
-
Jowaed A, Schmitt I, Kaut O, Wullner U. Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains. J Neurosci 2010;30:6355-6359.
-
(2010)
J Neurosci
, vol.30
, pp. 6355-6359
-
-
Jowaed, A.1
Schmitt, I.2
Kaut, O.3
Wullner, U.4
-
16
-
-
78649652766
-
CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease [serial online]
-
Matsumoto L, Takuma H, Tamaoka A, Kurisaki H, Date H, Tsuji S, Iwata A. CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease [serial online]. PloS One 2010;5:e15522.
-
(2010)
PloS One
, vol.5
, pp. e15522
-
-
Matsumoto, L.1
Takuma, H.2
Tamaoka, A.3
Kurisaki, H.4
Date, H.5
Tsuji, S.6
Iwata, A.7
-
17
-
-
0032716797
-
The methylation status of cytosines in a tau gene promoter region alters with age to downregulate transcriptional activity in human cerebral cortex
-
Tohgi H, Utsugisawa K, Nagane Y, Yoshimura M, Ukitsu M, Genda Y. The methylation status of cytosines in a tau gene promoter region alters with age to downregulate transcriptional activity in human cerebral cortex. Neurosci Lett 1999;275:89-92.
-
(1999)
Neurosci Lett
, vol.275
, pp. 89-92
-
-
Tohgi, H.1
Utsugisawa, K.2
Nagane, Y.3
Yoshimura, M.4
Ukitsu, M.5
Genda, Y.6
-
18
-
-
69449086451
-
DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain
-
Barrachina M, Ferrer I. DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain. J Neuropathol Exp Neurol 2009;68:880-891.
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 880-891
-
-
Barrachina, M.1
Ferrer, I.2
-
19
-
-
79952199669
-
Memory and Ageing Study Team. The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70-90 years
-
Sachdev PS, Brodaty H, Reppermund S, et al.; Memory and Ageing Study Team. The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70-90 years. Int Psychogeriatr 2010;22:1248-1264.
-
(2010)
Int Psychogeriatr
, vol.22
, pp. 1248-1264
-
-
Sachdev, P.S.1
Brodaty, H.2
Reppermund, S.3
-
20
-
-
28544435240
-
GSK3B polymorphisms alter transcription and splicing in Parkinson's disease
-
Kwok JB, Hallupp M, Loy CT, et al. GSK3B polymorphisms alter transcription and splicing in Parkinson's disease. Ann Neurol 2005;58:829-839.
-
(2005)
Ann Neurol
, vol.58
, pp. 829-839
-
-
Kwok, J.B.1
Hallupp, M.2
Loy, C.T.3
-
21
-
-
5444255434
-
Stages in the development of Parkinson's disease-related pathology
-
Braak H, Ghebremedhin E, Rub U, Bratzke H, Del Tredici K. Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res 2004;318:121-134.
-
(2004)
Cell Tissue Res
, vol.318
, pp. 121-134
-
-
Braak, H.1
Ghebremedhin, E.2
Rub, U.3
Bratzke, H.4
Del Tredici, K.5
-
22
-
-
33847019906
-
Rapid and quantitative method of allele-specific DNA methylation analysis
-
Wong HL, Byun HM, Kwan JM, Campan M, Ingles SA, Laird PW, Yang AS. Rapid and quantitative method of allele-specific DNA methylation analysis. Biotechniques 2006;41:734-739.
-
(2006)
Biotechniques
, vol.41
, pp. 734-739
-
-
Wong, H.L.1
Byun, H.M.2
Kwan, J.M.3
Campan, M.4
Ingles, S.A.5
Laird, P.W.6
Yang, A.S.7
-
23
-
-
38449102144
-
Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
-
Klug M, Rehli M. Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics 2006;1:127-130.
-
(2006)
Epigenetics
, vol.1
, pp. 127-130
-
-
Klug, M.1
Rehli, M.2
-
24
-
-
0035958821
-
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease
-
Muller T, Woitalla D, Hauptmann B, Fowler B, Kuhn W. Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease. Neurosci Lett 2001;308:54-56.
-
(2001)
Neurosci Lett
, vol.308
, pp. 54-56
-
-
Muller, T.1
Woitalla, D.2
Hauptmann, B.3
Fowler, B.4
Kuhn, W.5
-
25
-
-
55849090651
-
Glycogen synthase kinase-3 beta and tau genes interact in Alzheimer's disease
-
Kwok JB, Loy CT, Hamilton G, et al. Glycogen synthase kinase-3 beta and tau genes interact in Alzheimer's disease. Ann Neurol 2008;64:446-454.
-
(2008)
Ann Neurol
, vol.64
, pp. 446-454
-
-
Kwok, J.B.1
Loy, C.T.2
Hamilton, G.3
-
26
-
-
0033951680
-
Significant association between the tau gene A0/A0 genotype and Parkinson's disease
-
Pastor P, Ezquerra M, Munoz E, Marti MJ, Blesa R, Tolosa E, Oliva R. Significant association between the tau gene A0/A0 genotype and Parkinson's disease. Ann Neurol 2000;47:242-245.
-
(2000)
Ann Neurol
, vol.47
, pp. 242-245
-
-
Pastor, P.1
Ezquerra, M.2
Munoz, E.3
Marti, M.J.4
Blesa, R.5
Tolosa, E.6
Oliva, R.7
-
27
-
-
58149100151
-
PSG-PROGENI and GenePD Investigators, Coordinators and Molecular Genetic Laboratories. Genome wide association study for susceptibility genes contributing to familial Parkinson disease
-
Pankratz N, Wilk JB, Latourelle JC, et al.; PSG-PROGENI and GenePD Investigators, Coordinators and Molecular Genetic Laboratories. Genome wide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet 2009;124:593-605.
-
(2009)
Hum Genet
, vol.124
, pp. 593-605
-
-
Pankratz, N.1
Wilk, J.B.2
Latourelle, J.C.3
-
28
-
-
69449084444
-
The relationship of DNA methylation with age, gender and genotype in twins and healthy controls [serial online]
-
Boks MP, Derks EM, Weisenberger DJ, et al. The relationship of DNA methylation with age, gender and genotype in twins and healthy controls [serial online]. PloS One 2009;4:e6767.
-
(2009)
PloS One
, vol.4
, pp. e6767
-
-
Boks, M.P.1
Derks, E.M.2
Weisenberger, D.J.3
-
30
-
-
70350716441
-
Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences
-
Schilling E, El Chartouni C, Rehli M. Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences. Genome Res 2009;19:2028-2035.
-
(2009)
Genome Res
, vol.19
, pp. 2028-2035
-
-
Schilling, E.1
El Chartouni, C.2
Rehli, M.3
-
31
-
-
76049126281
-
Allelic skewing of DNA methylation is widespread across the genome
-
Schalkwyk LC, Meaburn EL, Smith R, et al. Allelic skewing of DNA methylation is widespread across the genome. Am J Hum Genet 2010;86:196-212.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 196-212
-
-
Schalkwyk, L.C.1
Meaburn, E.L.2
Smith, R.3
-
32
-
-
46249117780
-
Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation
-
Kerkel K, Spadola A, Yuan E, et al. Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nat Genet 2008;40:904-908.
-
(2008)
Nat Genet
, vol.40
, pp. 904-908
-
-
Kerkel, K.1
Spadola, A.2
Yuan, E.3
-
33
-
-
0031104930
-
DNA methylation directs a time dependent repression of transcription initiation
-
Kass SU, Landsberger N, Wolffe AP. DNA methylation directs a time dependent repression of transcription initiation. Curr Biol 1997;7:157-165.
-
(1997)
Curr Biol
, vol.7
, pp. 157-165
-
-
Kass, S.U.1
Landsberger, N.2
Wolffe, A.P.3
-
34
-
-
84873429169
-
Nutrition and neurodegeneration: epidemiological evidence and challenges for future research
-
Gillette-Guyonnet S, Secher M, Vellas B. Nutrition and neurodegeneration: epidemiological evidence and challenges for future research. Br J Clin Pharmacol 2013;75:738-755.
-
(2013)
Br J Clin Pharmacol
, vol.75
, pp. 738-755
-
-
Gillette-Guyonnet, S.1
Secher, M.2
Vellas, B.3
-
35
-
-
19344362520
-
Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis
-
Etminan M, Gill SS, Samii A. Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis. Lancet Neurol 2005;4:362-365.
-
(2005)
Lancet Neurol
, vol.4
, pp. 362-365
-
-
Etminan, M.1
Gill, S.S.2
Samii, A.3
-
36
-
-
84879788359
-
Gene-environment interactions in Parkinson's disease: specific evidence in humans and mammalian models
-
Cannon JR, Greenamyre JT. Gene-environment interactions in Parkinson's disease: specific evidence in humans and mammalian models. Neurobiol Dis 2013;57:38-46.
-
(2013)
Neurobiol Dis
, vol.57
, pp. 38-46
-
-
Cannon, J.R.1
Greenamyre, J.T.2
-
37
-
-
85005929986
-
Promoter DNA methylation regulates progranulin expression and is altered in FTLD
-
Banzhaf-Strathmann J, Claus R, Mucke O, et al. Promoter DNA methylation regulates progranulin expression and is altered in FTLD. Acta Neuropathol Commun 2013;1:16-16.
-
(2013)
Acta Neuropathol Commun
, vol.1
, pp. 16-16
-
-
Banzhaf-Strathmann, J.1
Claus, R.2
Mucke, O.3
-
38
-
-
84887611390
-
Vitamin and antioxidant rich diet increases MLH1 promoter DNA methylation in DMT2 subjects [serial online]
-
Switzeny OJ, Mullner E, Wagner KH, Brath H, Aumuller E, Haslberger AG. Vitamin and antioxidant rich diet increases MLH1 promoter DNA methylation in DMT2 subjects [serial online]. Clin Epigenet 2012;4:19.
-
(2012)
Clin Epigenet
, vol.4
, pp. 19
-
-
Switzeny, O.J.1
Mullner, E.2
Wagner, K.H.3
Brath, H.4
Aumuller, E.5
Haslberger, A.G.6
-
39
-
-
48249102700
-
Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study
-
Tobin JE, Latourelle JC, Lew MF, et al. Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology 2008;71:28-34.
-
(2008)
Neurology
, vol.71
, pp. 28-34
-
-
Tobin, J.E.1
Latourelle, J.C.2
Lew, M.F.3
-
40
-
-
69249231118
-
The effect of age and the H1c MAPT haplotype on MAPT expression
-
Hayesmoore JBG, Bray NJ, Cross WC, Owen MJ, O'Donovan MC, Morris HR. The effect of age and the H1c MAPT haplotype on MAPT expression. Neurobiol Aging 2009;30:1652-1656.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1652-1656
-
-
Hayesmoore, J.B.G.1
Bray, N.J.2
Cross, W.C.3
Owen, M.J.4
O'Donovan, M.C.5
Morris, H.R.6
-
41
-
-
83655181921
-
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease [serial online]
-
Morris M, Koyama A, Masliah E, Mucke L. Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease [serial online]. PloS One 2011;6:e29257.
-
(2011)
PloS One
, vol.6
, pp. e29257
-
-
Morris, M.1
Koyama, A.2
Masliah, E.3
Mucke, L.4
|