-
1
-
-
56649085323
-
Adrenocortical carcinoma in the United States: Treatment utilization and prognostic factors
-
Bilimoria KY, Shen WT, Elaraj D, et al. Adrenocortical carcinoma in the United States: treatment utilization and prognostic factors. Cancer. 2008;113:3130–3136.
-
(2008)
Cancer
, vol.113
, pp. 3130-3136
-
-
Bilimoria, K.Y.1
Shen, W.T.2
Elaraj, D.3
-
2
-
-
84895072281
-
Distinguishing adrenal cortical carcinomas and adenomas: A study of clinicopathological features and biomarkers
-
Wang C, Sun Y, Wu H, Zhao D, Chen J. Distinguishing adrenal cortical carcinomas and adenomas: a study of clinicopathological features and biomarkers. Histopathology. 2014;64:567–576.
-
(2014)
Histopathology
, vol.64
, pp. 567-576
-
-
Wang, C.1
Sun, Y.2
Wu, H.3
Zhao, D.4
Chen, J.5
-
4
-
-
76049095621
-
The European Network for the Study of Adrenal Tumors staging system is prognostically superior to the international union against cancer-staging system: A North American validation
-
Lughezzani G, Sun M, Perrotte P, et al. The European Network for the Study of Adrenal Tumors staging system is prognostically superior to the international union against cancer-staging system: a North American validation. Eur J Cancer. 2010;46:713–719.
-
(2010)
Eur J Cancer
, vol.46
, pp. 713-719
-
-
Lughezzani, G.1
Sun, M.2
Perrotte, P.3
-
5
-
-
33744952176
-
Clinical review: Adrenocortical carcinoma: Clinical update
-
Allolio B, Fassnacht M. Clinical review: adrenocortical carcinoma: clinical update. J Clin Endocrinol Metab. 2006;91:2027–2037.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2027-2037
-
-
Allolio, B.1
Fassnacht, M.2
-
6
-
-
45549094013
-
Comparative effects of chemotherapeutic agents on the growth and survival of human adrenal carcinoma cells in culture
-
Montoya M, Brown JW, Fishman LM. Comparative effects of chemotherapeutic agents on the growth and survival of human adrenal carcinoma cells in culture. Horm Metab Res. 2008;40:302–305.
-
(2008)
Horm Metab Res
, vol.40
, pp. 302-305
-
-
Montoya, M.1
Brown, J.W.2
Fishman, L.M.3
-
7
-
-
84930481235
-
Cisplatin resistance: A cellular self-defense mechanism resulting from multiple epigenetic and genetic changes
-
Shen DW, Pouliot LM, Hall MD, Gottesman MM. Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes. Pharmacol Rev. 2012;64:706–721.
-
(2012)
Pharmacol Rev
, vol.64
, pp. 706-721
-
-
Shen, D.W.1
Pouliot, L.M.2
Hall, M.D.3
Gottesman, M.M.4
-
8
-
-
84873660610
-
Autophagy in human health and disease
-
Choi AM, Ryter SW, Levine B. Autophagy in human health and disease. N Engl J Med. 2013;368:651–662.
-
(2013)
N Engl J Med
, vol.368
, pp. 651-662
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
9
-
-
67650095390
-
The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells
-
Lomonaco SL, Finniss S, Xiang C, et al. The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells. Int J Cancer. 2009;125:717–722.
-
(2009)
Int J Cancer
, vol.125
, pp. 717-722
-
-
Lomonaco, S.L.1
Finniss, S.2
Xiang, C.3
-
10
-
-
78649464206
-
Autophagy is a therapeutic target in anticancer drug resistance
-
Chen S, Rehman SK, Zhang W, Wen A, Yao L, Zhang J. Autophagy is a therapeutic target in anticancer drug resistance. Biochim Biophys Acta. 2010;1806:220–229.
-
(2010)
Biochim Biophys Acta
, vol.1806
, pp. 220-229
-
-
Chen, S.1
Rehman, S.K.2
Zhang, W.3
Wen, A.4
Yao, L.5
Zhang, J.6
-
11
-
-
79956224883
-
Targeting autophagy during cancer therapy to improve clinical outcomes
-
Levy JM, Thorburn A. Targeting autophagy during cancer therapy to improve clinical outcomes. Pharmacol Ther. 2011;131:130–141.
-
(2011)
Pharmacol Ther
, vol.131
, pp. 130-141
-
-
Levy, J.M.1
Thorburn, A.2
-
12
-
-
62949091373
-
Autophagy: A lysosomal degradation pathway with a central role in health and disease
-
Eskelinen EL, Saftig P. Autophagy: a lysosomal degradation pathway with a central role in health and disease. Biochim Biophys Acta. 2009;1793:664–673.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 664-673
-
-
Eskelinen, E.L.1
Saftig, P.2
-
13
-
-
56449107131
-
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma
-
Ding ZB, Shi YH, Zhou J, et al. Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma. Cancer Res. 2008;68:9167–9175.
-
(2008)
Cancer Res
, vol.68
, pp. 9167-9175
-
-
Ding, Z.B.1
Shi, Y.H.2
Zhou, J.3
-
14
-
-
65249180744
-
The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers
-
Li BX, Li CY, Peng RQ, et al. The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers. Autophagy. 2009;5:303–306.
-
(2009)
Autophagy
, vol.5
, pp. 303-306
-
-
Li, B.X.1
Li, C.Y.2
Peng, R.Q.3
-
15
-
-
84880785265
-
Aberrant expression of Beclin-1 and LC3 correlates with poor prognosis of human hypopharyngeal squamous cell carcinoma
-
Wang J, Pan XL, Ding LJ, Liu DY, Lei D, Jin T. Aberrant expression of Beclin-1 and LC3 correlates with poor prognosis of human hypopharyngeal squamous cell carcinoma. PLoS One. 2013;8:e69038.
-
(2013)
Plos One
, vol.8
-
-
Wang, J.1
Pan, X.L.2
Ding, L.J.3
Liu, D.Y.4
Lei, D.5
Jin, T.6
-
16
-
-
80053420059
-
Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis
-
Shi YH, Ding ZB, Zhou J, et al. Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis. Autophagy. 2011;7:1159–1172.
-
(2011)
Autophagy
, vol.7
, pp. 1159-1172
-
-
Shi, Y.H.1
Ding, Z.B.2
Zhou, J.3
-
17
-
-
84883196778
-
The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer
-
Cufi S, Vazquez-Martin A, Oliveras-Ferraros C, et al. The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer. Sci Rep. 2013;3:2469.
-
(2013)
Sci Rep
, vol.2469
, pp. 3
-
-
Cufi, S.1
Vazquez-Martin, A.2
Oliveras-Ferraros, C.3
-
18
-
-
84928746432
-
Chloroquine-enhanced efficacy of cisplatin in the treatment of hypopharyngeal carcinoma in xenograft mice
-
Zhao XG, Sun RJ, Yang XY, et al. Chloroquine-enhanced efficacy of cisplatin in the treatment of hypopharyngeal carcinoma in xenograft mice. PLoS One. 2015;10:e0126147.
-
(2015)
Plos One
, vol.10
-
-
Zhao, X.G.1
Sun, R.J.2
Yang, X.Y.3
-
19
-
-
77953383616
-
Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors
-
Wu Z, Chang PC, Yang JC, et al. Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors. Genes Cancer. 2010;1:40–49.
-
(2010)
Genes Cancer
, vol.1
, pp. 40-49
-
-
Wu, Z.1
Chang, P.C.2
Yang, J.C.3
-
20
-
-
79952229430
-
Pancreatic cancers require autophagy for tumor growth
-
Yang S, Wang X, Contino G, et al. Pancreatic cancers require autophagy for tumor growth. Genes Dev. 2011;25:717–729.
-
(2011)
Genes Dev
, vol.25
, pp. 717-729
-
-
Yang, S.1
Wang, X.2
Contino, G.3
-
21
-
-
84874398169
-
Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer
-
Zinn RL, Gardner EE, Dobromilskaya I, et al. Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Mol Cancer. 2013;12:16.
-
(2013)
Mol Cancer
, vol.12
, pp. 16
-
-
Zinn, R.L.1
Gardner, E.E.2
Dobromilskaya, I.3
-
22
-
-
84874405394
-
Autophagy inhibition for chemosensitization and radiosensitization in cancer: Do the preclinical data support this therapeutic strategy
-
Bristol ML, Emery SM, Maycotte P, Thorburn A, Chakradeo S, Gewirtz DA. Autophagy inhibition for chemosensitization and radiosensitization in cancer: do the preclinical data support this therapeutic strategy. J Pharmacol Exp Ther. 2013;344:544–552.
-
(2013)
J Pharmacol Exp Ther
, vol.344
, pp. 544-552
-
-
Bristol, M.L.1
Emery, S.M.2
Maycotte, P.3
Thorburn, A.4
Chakradeo, S.5
Gewirtz, D.A.6
-
23
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 2004;23:2891–2906.
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
24
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
Takamura A, Komatsu M, Hara T, et al. Autophagy-deficient mice develop multiple liver tumors. Genes Dev. 2011;25:795–800.
-
(2011)
Genes Dev
, vol.25
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
-
25
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell. 2006;10:51–64.
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
-
26
-
-
84884161479
-
Promoting colonization in metastatic HCC cells by modulation of autophagy
-
Peng YF, Shi YH, Shen YH, et al. Promoting colonization in metastatic HCC cells by modulation of autophagy. PLoS One. 2013;8:e74407.
-
(2013)
Plos One
, vol.8
-
-
Peng, Y.F.1
Shi, Y.H.2
Shen, Y.H.3
-
27
-
-
79955949199
-
Rosiglitazone induces autophagy in H295R and cell cycle deregulation in SW13 adrenocortical cancer cells
-
Cerquetti L, Sampaoli C, Amendola D, et al. Rosiglitazone induces autophagy in H295R and cell cycle deregulation in SW13 adrenocortical cancer cells. Exp Cell Res. 2011;317:1397–1410.
-
(2011)
Exp Cell Res
, vol.317
, pp. 1397-1410
-
-
Cerquetti, L.1
Sampaoli, C.2
Amendola, D.3
-
28
-
-
59449084843
-
Limited prognostic value of the 2004 International Union Against Cancer staging classification for adrenocortical carcinoma: Proposal for a Revised TNM Classification
-
Fassnacht M, Johanssen S, Quinkler M, et al. Limited prognostic value of the 2004 International Union Against Cancer staging classification for adrenocortical carcinoma: proposal for a Revised TNM Classification. Cancer. 2009;115:243–250.
-
(2009)
Cancer
, vol.115
, pp. 243-250
-
-
Fassnacht, M.1
Johanssen, S.2
Quinkler, M.3
-
29
-
-
84938212786
-
Targeting of mTORC2 may have advantages over selective targeting of mTORC1 in the treatment of malignant pheochromocytoma
-
Zhang X, Wang X, Xu T, Zhong S, Shen Z. Targeting of mTORC2 may have advantages over selective targeting of mTORC1 in the treatment of malignant pheochromocytoma. Tumour Biol. 2015;36:5273–5281.
-
(2015)
Tumour Biol
, vol.36
, pp. 5273-5281
-
-
Zhang, X.1
Wang, X.2
Xu, T.3
Zhong, S.4
Shen, Z.5
-
30
-
-
84906268736
-
MicroRNA-145 directly targets the insulin-like growth factor receptor I in human bladder cancer cells
-
Zhu Z, Xu T, Wang L, et al. MicroRNA-145 directly targets the insulin-like growth factor receptor I in human bladder cancer cells. FEBS Lett. 2014;588:3180–3185.
-
(2014)
FEBS Lett
, vol.588
, pp. 3180-3185
-
-
Zhu, Z.1
Xu, T.2
Wang, L.3
-
31
-
-
0028836002
-
Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles
-
Biederbick A, Kern HF, Elsasser HP. Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol. 1995;66:3–14.
-
(1995)
Eur J Cell Biol
, vol.66
, pp. 3-14
-
-
Biederbick, A.1
Kern, H.F.2
Elsasser, H.P.3
-
32
-
-
84872190720
-
Antitumor effects of rapamycin in pancreatic cancer cells by inducing apoptosis and autophagy
-
Dai ZJ, Gao J, Ma XB, et al. Antitumor effects of rapamycin in pancreatic cancer cells by inducing apoptosis and autophagy. Int J Mol Sci. 2012;14:273–285.
-
(2012)
Int J Mol Sci
, vol.14
, pp. 273-285
-
-
Dai, Z.J.1
Gao, J.2
Ma, X.B.3
-
33
-
-
84918784157
-
The dual mTORC1 and mTORC2 inhibitor PP242 shows strong antitumor activity in a pheochromocytoma PC12 cell tumor model
-
Zhang X, Wang X, Qin L, et al. The dual mTORC1 and mTORC2 inhibitor PP242 shows strong antitumor activity in a pheochromocytoma PC12 cell tumor model. Urology. 2015;85:273.e1–273.e7.
-
(2015)
Urology
, vol.85
, pp. e1-e273
-
-
Zhang, X.1
Wang, X.2
Qin, L.3
-
34
-
-
0001488499
-
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
-
Liang XH, Kleeman LK, Jiang HH, et al. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol. 1998;72:8586–8596.
-
(1998)
J Virol
, vol.72
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
-
35
-
-
50249183899
-
Autophagy revisited: A conversation with Christian de Duve
-
Klionsky DJ. Autophagy revisited: a conversation with Christian de Duve. Autophagy. 2008;4:740–743.
-
(2008)
Autophagy
, vol.4
, pp. 740-743
-
-
Klionsky, D.J.1
-
36
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell. 2004;6:463–477.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
37
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 2000;19:5720–5728.
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
-
38
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
Mathew R, Karp CM, Beaudoin B, et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell. 2009;137:1062–1075.
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
-
39
-
-
33645115547
-
Adding chloroquine to conventional treatment for glioblastoma multiforme: A randomized, double-blind, placebo-controlled trial
-
Sotelo J, Briceno E, Lopez-Gonzalez MA. Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2006;144:337–343.
-
(2006)
Ann Intern Med
, vol.144
, pp. 337-343
-
-
Sotelo, J.1
Briceno, E.2
Lopez-Gonzalez, M.A.3
-
40
-
-
77649286874
-
Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy
-
Ren JH, He WS, Nong L, et al. Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy. Cancer Biother Radiopharm. 2010;25:75–80.
-
(2010)
Cancer Biother Radiopharm
, vol.25
, pp. 75-80
-
-
Ren, J.H.1
He, W.S.2
Nong, L.3
-
41
-
-
84871940714
-
Chloroquine in cancer therapy: A double-edged sword of autophagy
-
Kimura T, Takabatake Y, Takahashi A, Isaka Y. Chloroquine in cancer therapy: a double-edged sword of autophagy. Cancer Res. 2013;73:3–7.
-
(2013)
Cancer Res
, vol.73
, pp. 3-7
-
-
Kimura, T.1
Takabatake, Y.2
Takahashi, A.3
Isaka, Y.4
-
42
-
-
84857267849
-
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
-
Maycotte P, Aryal S, Cummings CT, Thorburn J, Morgan MJ, Thorburn A. Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. Autophagy. 2012;8:200–212.
-
(2012)
Autophagy
, vol.8
, pp. 200-212
-
-
Maycotte, P.1
Aryal, S.2
Cummings, C.T.3
Thorburn, J.4
Morgan, M.J.5
Thorburn, A.6
-
43
-
-
84905706340
-
Tumor vessel normalization by chloroquine independent of autophagy
-
Maes H, Kuchnio A, Peric A, et al. Tumor vessel normalization by chloroquine independent of autophagy. Cancer Cell. 2014;26:190–206.
-
(2014)
Cancer Cell
, vol.26
, pp. 190-206
-
-
Maes, H.1
Kuchnio, A.2
Peric, A.3
-
44
-
-
33645307960
-
Inhibition of endosomal sequestration of basic anticancer drugs: Influence on cytotoxicity and tissue penetration
-
Lee CM, Tannock IF. Inhibition of endosomal sequestration of basic anticancer drugs: influence on cytotoxicity and tissue penetration. Br J Cancer. 2006;94:863–869.
-
(2006)
Br J Cancer
, vol.94
, pp. 863-869
-
-
Lee, C.M.1
Tannock, I.F.2
|