Evaluation of Macaca mulatta as a model for genotoxicity studies

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 673, Issue 1, 2009, Pages 21-28

  Dobrovolsky, Vasily N ^a   Shaddock, Joseph G ^a   Mittelstaedt, Roberta A ^a   Manjanatha, Mugimane G ^a   Miura, Daishiro ^a,b   Uchikawa, Makoto ^c   Mattison, Donald R ^d   Morris, Suzanne M ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b TEIJIN PHARMA LIMITED   (Japan)

^c Japanese Red Central Blood Center   (Japan)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Cloning; ENU; Erythrocytes; Flow cytometry; HPRT; Lymphocytes; Mutation; PIG A; Rhesus monkey

Indexed keywords

AEROLYSIN; ETHYLNITROSOUREA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; TIOGUANINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD ANALYSIS; CELL MUTANT; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROCYTE MEMBRANE; FLOW CYTOMETRY; GENETIC MODEL; GENOTOXICITY; IN VITRO STUDY; LEUKOCYTE; MACACA; MALE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; RISK ASSESSMENT; VALIDATION STUDY; VEIN PUNCTURE;

ANIMALS; BACTERIAL TOXINS; CELLS, CULTURED; ERYTHROCYTES; FLOW CYTOMETRY; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LYMPHOCYTES; MACACA MULATTA; MALE; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MUTAGENS; MUTATION; PORE FORMING CYTOTOXIC PROTEINS; THIOGUANINE;

ANIMALIA; MACACA MULATTA; PRIMATES;

EID: 58949084578     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.11.006     Document Type: Article

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