Programmed Self-Assembly of an Active P22-Cas9 Nanocarrier System

Molecular Pharmaceutics

Volumn 13, Issue 3, 2016, Pages 1191-1196

  Qazi, Shefah ^a,b   Miettinen, Heini M ^a   Wilkinson, Royce A ^a   McCoy, Kimberly ^b   Douglas, Trevor ^b   Wiedenheft, Blake ^a  

^a MONTANA STATE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Cas9; delivery vehicle; gene therapy; genome editing; P22 bacteriophage; virus like particles; VLP

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; DOUBLE STRANDED DNA; ENDONUCLEASE; GUIDE RNA; NANOCARRIER; PLASMID DNA; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; DRUG CARRIER; NANOPARTICLE;

ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; DNA CLEAVAGE; DNA PACKAGING; ENTEROBACTERIA PHAGE P22; GEL ELECTROPHORESIS; LIGHT SCATTERING; NANOENCAPSULATION; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TRANSFORMED CELL; TRANSMISSION ELECTRON MICROSCOPY; VIRUS CAPSID; VIRUS LIKE AGENT; CHEMISTRY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DRUG DELIVERY SYSTEM; GENETIC ENGINEERING; GENETICS; HUMAN; METABOLISM; PROCEDURES; RNA EDITING;

BACTERIAL PROTEINS; BACTERIOPHAGE P22; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDONUCLEASES; GENETIC ENGINEERING; HUMANS; NANOPARTICLES; RNA EDITING;

EID: 84960153565     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00822     Document Type: Article

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