Thiostrepton Variants Containing a Contracted Quinaldic Acid Macrocycle Result from Mutagenesis of the Second Residue

ACS Chemical Biology

Volumn 11, Issue 2, 2016, Pages 415-424

  Zhang, Feifei ^a   Li, Chaoxuan ^a   Kelly, Wendy L ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; MACROCYCLIC COMPOUND; QUINALDIC ACID; THIOSTREPTON; THIOSTREPTON A; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; QUINOLINE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIMALARIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACILLUS; DRUG POTENCY; ENTEROCOCCUS; IC50; MICHAEL ADDITION; MINIMUM INHIBITORY CONCENTRATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; BACTERIAL INFECTIONS; BACTERIUM; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; SITE DIRECTED MUTAGENESIS; STREPTOMYCES;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; QUINOLINES; STREPTOMYCES; THIOSTREPTON;

EID: 84960120818     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.5b00731     Document Type: Article

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