Soft matrices inhibit cell proliferation and inactivate the fibrotic phenotype of deep endometriotic stromal cells in vitro

Human Reproduction

Volumn 31, Issue 3, 2016, Pages 541-553

  Matsuzaki, Sachiko ^a,b,c   Canis, Michel ^a,b,c   Pouly, Jean Luc ^a   Darcha, Claude ^a  

^a UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c CNRS   (France)

Author keywords

collagen; endometriosis; endometrium; extracellular matrix stiffness; fibrosis; myofibroblast

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; CYCLIN D1; F ACTIN; INTERSTITIAL COLLAGENASE; KI 67 ANTIGEN; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; POLYACRYLAMIDE GEL; PROCOLLAGEN; PROCOLLAGEN TYPE I; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; COLLAGEN;

ADULT; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DEEP INFILTRATING ENDOMETRIOTIC STROMAL CELL; ENDOMETRIOSIS; ENDOMETRIUM CELL; EXTRACELLULAR MATRIX; FEMALE; FEMALE INFERTILITY; FIBROMA; FIBROSIS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; RIGIDITY; STRESS FIBER; STROMA CELL; BIOSYNTHESIS; CELL COMMUNICATION; CELL CULTURE; CELL DIFFERENTIATION; CHEMISTRY; ENDOMETRIUM; GENETICS; METABOLISM; PATHOLOGY;

ADULT; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; CYCLIN D1; ENDOMETRIOSIS; ENDOMETRIUM; EXTRACELLULAR MATRIX; FEMALE; FIBROSIS; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 14; PHENOTYPE; RNA, MESSENGER; STROMAL CELLS;

EID: 84960120770     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dev333     Document Type: Article

References (36)

1. Arthur MJ. Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis. Am J Physiol Gastrointest Liver Physiol. 2000; 279: G245-G249.
2. Biernacka A, Dobaczewski M, Frangogiannis NG. TGF-b signaling in fibrosis. Growth Factors. 2007; 29: 196-202.
3. Bonnans C, Chou J, Werb Z. Remodelling the extracellular matrix in development and disease. Nat Rev Mol Cell Biol. 2014; 15: 786-801.
4. Booth AJ, Hadley R, Cornett AM, Dreffs AA, Matthes SA, Tsui JL, Weiss K, Horowitz JC, Fiore VF, BarkerTHet al. Acellular normal and fibrotichuman lung matrices as a culture system for in vitro investigation. Am J Respir Crit Care Med. 2012; 186: 866-876.
5. Brown AC, Fiore VF, Sulchek TA, Barker TH. Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-Associated epithelial-To-mesenchymal transitions. J Pathol. 2013; 229: 25-35.
6. Cox TR, Erler JT. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis Model Mech. 2011; 4: 165-178.
7. Fischer RS, Myers KA, Gardel ML, Waterman CM. Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior. Nat Protoc. 2012; 7: 2056-2066.
8. Georges PC, Hui JJ, Gombos Z, McCormick ME, Wang AY, Uemura M, Mick R, Janmey PA, Furth EE, Wells RG. Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis. Am J Physiol Gastrointest Liver Physiol. 2007; 293: G1147-G1154.
9. Giudice LC, Kao LC. Endometriosis. Lancet. 2004; 364: 1789-1799.
10. Harada T, Kaponis A, Iwabe T, Taniguchi F, Makrydimas G, Sofikitis N, Paschopoulos M, Paraskevaidis E, Terakawa N. Apoptosis in human endometrium and endometriosis. Hum Reprod Update. 2004; 10: 29-38.
11. Review. Hintz B. Formation and function of the myofibroblast during tissue repair. J Invest Dermatol. 2007; 127: 526-537. Review
12. Hinz B, Phan SH, Thannickal VJ, Galli A, Bochaton-Piallat ML, Gabbiani G. The myofibroblast: one function, multiple origins. Am J Pathol. 2007; 170: 1807-1816. Review
13. Holmbeck K, Bianco P, Caterina J, Yamada S, Kromer M, Kuznetsov SA, Mankani M, Robey PG, Poole AR, Pidoux I et al. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell. 1999; 99: 81-92.
14. Jiang X, Asbach P, Streitberger KJ, Thomas A, Hamm B, Braun J, Sack I, Guo J. In vivo high-resolution magnetic resonance elastography of the uterine corpus and cervix. Eur Radiol. 2014; 24: 3025-3033.
15. Johnson LA, Rodansky ES, Sauder KL, Horowitz JC, Mih JD, Tschumperlin DJ, Higgins PD. Matrix stiffness corresponding to strictured bowel induces a fibrogenic response in human colonic fibroblasts. Inflamm Bowel Dis. 2013; 19: 891-903.
16. Kokorine I, Nisolle M, Donnez J, Eeckhout Y, Courtoy PJ, Marbaix E. Expression of interstitial collagenase (matrix metalloproteinase-1) is related to the activity of human endometriotic lesions. Fertil Steril. 1997; 68: 246-251.
17. Koninckx PR, Ussia A, Adamyan L, Wattiez A, Donnez J.Deep endometriosis: definition, diagnosis, and treatment. Fertil Steril. 2012; 98: 564-571.
18. Leask A, Abraham DJ. TGF-beta signaling and the fibrotic response. FASEB J. 2004; 18: 816-827.
19. Lee GY, Kenny PA, Lee EH, Bissell MJ. Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods. 2007; 4: 359-365.
20. Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, WeningerWet al. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell. 2009; 139: 891-906.
21. Liu F, Mih JD, Shea BS, Kho AT, Sharif AS, Tager AM, Tschumperlin DJ. Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression. J Cell Biol. 2010; 190: 693-706.
22. Matsuzaki S, Darcha C. In vitro effects of a small-molecule antagonist of the Tcf/β-catenin complex on endometrial and endometriotic cells of patients with endometriosis. PLoS One 2013a; 8: e61690.
23. Matsuzaki S, Darcha C. Involvement of the Wnt/b-catenin signaling pathway in the cellular and molecular mechanisms of fibrosis in endometriosis. PLoS One 2013b; 8: e76808.
24. Matsuzaki S, DarchaC. Antifibrotic properties of epigallocatechin-3-gallate in endometriosis. Hum Reprod. 2014; 29: 1677-1687.
25. Matsuzaki S, Darcha C. Co-operation between the AKT and ERK signaling pathways may support growth of deep endometriosis in a fibrotic microenvironment in vitro. Hum Reprod. 2015; 30: 1606-1616.
26. Matsuzaki S, Canis M, Darcha C, Dechelotte P, Pouly JL, Bruhat MA. Fibrogenesis in peritoneal endometriosis A semi-quantitative analysis of type-I collagen. Gynecol Obstet Invest. 1999; 47: 197-199.
27. McKleroy W, Lee TH, Atabai K. Always cleave up your mess: targeting collagen degradation to treat tissue fibrosis. Am J Physiol Lung Cell Mol Physiol. 2013; 304: L709-L721.
28. Nisolle M, Donnez J. Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities. Fertil Steril. 1997; 68: 585-596.
29. Omwandho CO, Konrad L, Halis G, Oehmke F, Tinneberg HR. Role of TGF-betas in normal human endometrium and endometriosis. Hum Reprod. 2010; 25: 101-109.
30. Paner GP, Shen SS, Lapetino S, Venkataraman G, Barkan GA, Quek ML, Ro JY, Amin MB. Diagnostic utility of antibody to smoothelin in the distinction of muscularis propria from muscularis mucosae of the urinary bladder: a potential ancillary tool in the pathologic staging of invasive urothelial carcinoma. Am J Surg Pathol. 2009; 33: 91-98.
31. Parker MW, Rossi D, Peterson M, Smith K, Sikström K, White ES, Connett JE, Henke CA, Larsson O, Bitterman PB. Fibrotic extracellular matrix activates a profibrotic positive feedback loop. J Clin Invest. 2014; 124: 1622-1635.
32. Schrader J, Gordon-Walker TT, Aucott RL, van Deemter M, Quaas A, Walsh S, Benten D, Forbes SJ, Wells RG, Iredale JP. Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells. Hepatology. 2011; 53: 1192-1205.
33. Smithmyer ME, Sawicki LA, Kloxin AM. Hydrogel scaffolds as in vitro models to study fibroblast activation in wound healing and disease. Biomater Sci. 2014; 2: 634-650.
34. Tilghman RW, Cowan CR, Mih JD, Koryakina Y, Gioeli D, Slack-Davis JK, Blackman BR, Tschumperlin DJ, Parsons JT. Matrix rigidity regulates cancer cell growth and cellular phenotype. PLoS One. 2010; 5: e12905.
35. Young VJ, Brown JK, Saunders PT, Duncan WC, HorneAW. The peritoneum is both a source and target of TGF-b in women with endometriosis. PLoS One. 2014; 9: e106773.
36. Zhou Y, Huang X, Hecker L, Kurundkar D, Kurundkar A, Liu H, Jin TH, Desai L, Bernard K, Thannickal VJ. Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. J Clin Invest. 2013; 123: 1096-1108.