The peritoneum is both a source and target of TGF-b in women with endometriosis

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Young, Vicky J ^a   Brown, Jeremy K ^a   Saunders, Philippa T K ^a   Duncan, W Colin ^a   Horne, Andrew W ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN 6; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; NOTCH1 RECEPTOR; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN BINDING;

ADULT; ARTICLE; CARCINOGENESIS; CDC6 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; CREB1 GENE; ENDOMETRIOSIS; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; ID1 GENE; ID3 GENE; IMMUNOHISTOCHEMISTRY; MAPKB GENE; MESOTHELIUM CELL; NOTCH1 GENE; PERITONEAL BIOPSY; PERITONEAL FLUID; PERITONEUM; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ADOLESCENT; ASCITES FLUID; BIOSYNTHESIS; CASE CONTROL STUDY; EPITHELIUM; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION; PROTEIN TRANSPORT; SECRETION (PROCESS); YOUNG ADULT;

ADOLESCENT; ADULT; ASCITIC FLUID; CASE-CONTROL STUDIES; ENDOMETRIOSIS; EPITHELIUM; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MIDDLE AGED; PERITONEUM; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTOR, EPIDERMAL GROWTH FACTOR; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; YOUNG ADULT;

EID: 84937714150     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106773     Document Type: Article

References (53)

1. Giudice LC (2010) Clinical practice. Endometriosis. N Engl J Med 362: 2389-2398.
2. Simoens S, Dunselman G, Dirksen C, Hummelshoj L, Bokor A, et al. (2012) The burden of endometriosis: costs and quality of life of women with endometriosis and treated in referral centres. Hum Reprod 27: 1292-1299.
3. Candiani BG, Fedele L, Vercellini P, Bianchi S, Di Nola G (1991) Repetitive conservative surgery for recurrence of endometriosis. Obstet Gynecol 77: 421-424.
4. Kuohung W, Jones GL, Vitonis AF, Cramer DW, Kennedy SH, et al. (2002) Characteristics of patients with endometriosis in the United States and the United Kingdom. Fertil Steril 78: 767-772.
5. Young VJ, Brown JK, Saunders PTK, Horne AW (2013) The role of the peritoneum in the pathogenesis of endometriosis. Human Reproduction Update 19: 558-569.
6. Nisolle M, Casanas-Roux F, Donnez J (2000) Early-stage endometriosis: adhesion and growth of human menstrual endometrium in nude mice. Fertil Steril 74: 306-312.
7. Witz CA, Cho S, Centonze VE, Montoya-Rodriguez IA, Schenken RS (2003) Time series analysis of transmesothelial invasion by endometrial stromal and epithelial cells using three-dimensional confocal microscopy. Fertil Steril 79 Suppl 1: 770-778.
8. Lucidi RS, Witz CA, Chrisco M, Binkley PA, Shain SA, et al. (2005) A novel in vitro model of the early endometriotic lesion demonstrates that attachment of endometrial cells to mesothelial cells is dependent on the source of endometrial cells. Fertil Steril 84: 16-21.
9. Sotnikova YN, Antsiferova SY, Posiseeva VL, Shishkov ND, Posiseev VD, et al. (2010) Mechanisms regulating invasiveness and growth of endometriosis lesions in rat experimental model and in humans. CORD Conference Proceedings 93: 2701-2705.
10. Kyama C, Mihalyi A, Simsa P (2006) Endometrial-peritoneal interactions and endometriosis. World Endometriosis Society.
11. Ishimaru T, Khan KN, Fujishita A, Kitajima M, Masuzaki H (2004) Hepatocyte growth factor may be involved in cellular changes to the peritoneal mesothelium adjacent to pelvic endometriosis. Fertil Steril 81 Suppl 1: 810-818.
12. Dunselman GA, Groothuis PG, de Goeij AF, Evers JL (2001) The Mesothelium, Teflon or Velcro? Mesothelium in endometriosis pathogenesis. Hum Reprod 16: 605-607.
13. Song M, Karabina SA, Kavtaradze N, Murphy AA, Parthasarathy S (2003)\ Presence of endometrial epithelial cells in the peritoneal cavity and the mesothelial inflammatory response. Fertil Steril 79 Suppl 1: 789-794.
14. Wu R, Van der Hoek KH, Ryan NK, Norman RJ, Robker RL (2004) Macrophage contributions to ovarian function. Human Reproduction Update 10: 119-133.
15. Hull ML, Johan MZ, Hodge WL, Robertson SA, Ingman WV (2012) Hostderived TGFB1 deficiency suppresses lesion development in a mouse model of endometriosis. Am J Pathol 180: 880-887.
16. Omwandho COA, Konrad L, Halis G, Oehmke F, Tinneberg H-R (2010) Role of TGF-betas in normal human endometrium and endometriosis. Hum Reprod 25: 101-109.
17. Dijke ten P, Hill SC (2004) New insights into TGF-β-Smad signalling. Trends Biochem Sci 29: 265-273.
18. Schmierer B, Hill CS (2007) TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 8: 970-982.
19. Pizzo A, Salmeri FM, Ardita FV, Sofob V, Tripepi M, et al. (2002) Behaviour of cytokine levels in serum and peritoneal fluid of women with endometriosis. Gynecol Obstet Invest. 54(2): 82-87.
20. Oosterlynck DJ, Meuleman C, Waer M, Koninckx PR (1994) Transforming growth factor-beta activity is increased in peritoneal fluid from women with endometriosis. Obstet Gynecol 83: 287-292.
21. Kupker W, Schultze-Mosgau A, Diedrich K (1998) Paracrine changes in the peritoneal environment of women with endometriosis. Human Reproduction Update 4: 719-723.
22. Johnson MC, Torres M, Alves A, Bacallao K, Fuentes A, et al. (2005) Augmented cell survival in eutopic endometrium from women with endometriosis: expression of c-myc, TGF-beta1 and bax genes. Reprod Biol Endocrinol 3: 45-45.
23. Mizumoto Y (1996) [Changes in NK activities and TGF- beta concentrations in the peritoneal cavity in endometriosis and their interaction related with infertility]. Nippon Sanka Fujinka Gakkai Zasshi 48: 379-385.
24. Hull ML, Escareno CR, Godsland JM, Doig JR, Johnson CM, et al. (2008) Endometrial-peritoneal interactions during endometriotic lesion establishment. Am J Pathol 173: 700-715.
25. Fegan KS, Rae MT, Critchley HOD, Hillier SG (2008) Anti-inflammatory steroid signalling in the human peritoneum. J Endocrinol 196: 369-376.
26. Mahmood TA, Templeton A (1991) Prevalence and genesis of endometriosis. Hum Reprod 6: 544-549.
27. Espinoza I, Miele L (2013) Cancer Letters. Cancer Letters 341: 41-45.
28. Kobayashi H, Yamada Y, Morioka S, Niiro E, Shigemitsu A, et al. (2013) Mechanism of pain generation for endometriosis-associated pelvic pain. Archives of Gynecology and Obstetrics 289: 13-21.
29. Ruzinova MB, Benezra R (2003) Id proteins in development, cell cycle and cancer. Trends in Cell Biology 13: 410-418.
30. Sabapathy K (2012) Role of the JNK pathway in human diseases. Prog Mol Biol Transl Sci 106: 145-169.
31. Petrakis TG, Vougas K, Gorgoulis VG (2012) Cdc6: a multi-functional molecular switch with critical role in carcinogenesis. Transcription 3: 124-129.
32. Vervoort SJ, van Boxtel R, Coffer PJ (2012) The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe? 32: 3397-3409.
33. Oosterlynck DJD, Meuleman CC, Sobis HH, Vandeputte MM, Koninckx PRP (1993) Angiogenic activity of peritoneal fluid from women with endometriosis. Fertil Steril 59: 778-782.
34. Pizzo A, Salmeri FM, Ardita FV, Sofo V, Tripepi M, et al. (2002) Behaviour of cytokine levels in serum and peritoneal fluid of women with endometriosis. Gynecologic and Obstetric Investigation 54: 82-87.
35. Komiyama S-I, Aoki D, Komiyama M, Nozawa S (2007) Local activation of TGF-beta1 at endometriosis sites. J Reprod Med 52: 306-312.
36. Offner FA, Feichtinger H, Stadlmann S, Obrist P, Marth C, et al. (1996) Transforming growth factor-beta synthesis by human peritoneal mesothelial cells - Induction by interleukin-1. Am J Pathol 148: 1679-1688.
37. D'Hooghe TM, Bambra CS, Xiao L, Peixe K (2001) Effect of menstruation and intrapelvic injection of endometrium on inflammatory parameters of peritoneal fluid in the baboon (Papio anubis and Papio cynocephalus). Am J Obstet Gynecol 184(5): 917-25.
38. Suen J-L, Chang Y, Chiu P-R, Hsieh T-H, Hsi E, et al. (2014) Serum Level of IL-10 Is Increased in Patients with Endometriosis, and IL-10 Promotes the Growth of Lesions in a Murine Model. Am J Pathol 184: 464-471.
39. Ho HN, Wu MY, Chao KH, Chen CD, Chen SU, et al. (1997) Peritoneal interleukin-10 increases with decrease in activated CD4+ T lymphocytes in women with endometriosis. Hum Reprod 12: 2528-2533.
40. Matsuzaki S, Darcha C (2012) Epithelial to mesenchymal transition-like and mesenchymal to epithelial transition-like processes might be involved in the pathogenesis of pelvic endometriosis. Hum Reprod 27: 712-721.
41. Bartley J, Jülicher A, Hotz B, Mechsner S, Hotz H (2013) Epithelial to mesenchymal transition (EMT) seems to be regulated differently in endometriosis and the endometrium. Archives of Gynecology and Obstetrics.
42. Wong YC, Wang X, Ling MT (2004) Id-1 expression and cell survival. Apoptosis 9: 279-289.
43. Ling MT (2005) Overexpression of Id-1 in prostate cancer cells promotes angiogenesis through the activation of vascular endothelial growth factor (VEGF). Carcinogenesis 26: 1668-1676.
44. Sun R, Chen W, Zhao X, Li T, Song Q (2011) Acheron regulates vascular endothelial proliferation and angiogenesis together with Id1 during wound healing. Cell Biochem Funct 29: 636-640.
45. Nap AW (2004) Antiangiogenesis Therapy for Endometriosis. J Clin Endocrinol Metab 89: 1089-1095.
46. Hull ML, Charnock-Jones DS, Chan CLK, Bruner-Tran KL, Osteen KG, et al. (2003) Antiangiogenic agents are effective inhibitors of endometriosis. J Clin Endocrinol Metab 88: 2889-2899.
47. Taylor RN, Lebovic DI, Mueller MD (2002) Angiogenic Factors in Endometriosis. Annals of the New York Academy of Sciences 955: 89-100.
48. Taniguchi F, Harada T, Miyakoda H, Iwabe T, Deura I, et al. (2009) TAK1 activation for cytokine synthesis and proliferation of endometriotic cells. Mol Cell Endocrinol 307: 196-204.
49. Tagashria Y, Taniguchi F, Harada T, Ikeda A, Watanabe A, et al. (2009) Interleukin-10 attenuates TNF-a-induced interleukin-6 production in endometriotic stromal cells. Fertil Steril 91: 2185-2192.
50. Deng H, Yu F, Chen J, Zhao Y, Xiang J, et al. (2008) Phosphorylation of bad at Thr-201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1. Journal of Biological Chemistry 283: 20754-20760.
51. Yu C, Minemoto Y, Zhang J, Liu J, Tang F, et al. (2004) JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. Mol Cell 13: 329-340.
52. Danial NN, Gramm CF, Scorrano L, Zhang CY, Krauss S, et al. (2003) BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature 424: 952-956.
53. Young VJ, Brown JK, Maybin J, Saunders PTK, Duncan WC, et al. (2014) Transforming growth factor-β induced Warburg-like metabolic reprogramming may underpin the development of peritoneal endometriosis. J Clin Endocrinol Metab: jc. 2014-1026.