Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk

Human Genetics

Volumn 135, Issue 5, 2016, Pages 453-467

  Tragante, Vinicius ^a   Asselbergs, Folkert W ^a,b,c   Swerdlow, Daniel I ^b,d   Palmer, Tom M ^e   Moore, Jason H ^f   de Bakker, Paul I W ^a   Keating, Brendan J ^g,h   Holmes, Michael V ^g,i  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c INTERUNIVERSITY CARDIOLOGY INSTITUTE OF THE NETHERLANDS   (Netherlands)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e LANCASTER UNIVERSITY   (United Kingdom)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

ⁱ UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; LIPID;

ALDH2 GENE; APOB GENE; ARTICLE; CETP GENE; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DYSGLYCEMIA; GENE IDENTIFICATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC DATABASE; GLUCOSE BLOOD LEVEL; HMGCR GENE; HUMAN; ISCHEMIC HEART DISEASE; LPA GENE; MENDELIAN RANDOMIZATION ANALYSIS; NPC1L1 GENE; PCSK9 GENE; PLG GENE; PRIORITY JOURNAL; RISK REDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; ANALYSIS; CHEMISTRY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; GLYCEMIC INDEX; RISK FACTOR;

BIOMARKERS; BLOOD GLUCOSE; CHOLESTEROL, LDL; CORONARY ARTERY DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; GLYCEMIC INDEX; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LIPIDS; MENDELIAN RANDOMIZATION ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84960112879     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-016-1647-9     Document Type: Article

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