메뉴 건너뛰기




Volumn 109, Issue 2, 2016, Pages 283-293

Nanotherapeutics for inhibition of atherogenesis and modulation of inflammation in atherosclerotic plaques

Author keywords

Alpha Tocopherol; Atherosclerosis; Inflammation; Macrophages; Nanotechnology

Indexed keywords

ALPHA TOCOPHEROL; AMPHOPHILE; BIOLOGICAL MARKER; MACROGOL; NANOPARTICLE; POLYMER; SCAVENGER RECEPTOR; LOW DENSITY LIPOPROTEIN;

EID: 84959901286     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvv237     Document Type: Article
Times cited : (22)

References (54)
  • 2
    • 0029883764 scopus 로고    scopus 로고
    • The role of oxidized lipoproteins in atherogenesis
    • Berliner JA, Heinecke JW. The role of oxidized lipoproteins in atherogenesis. Free Radic Biol Med 1996;20:707-727.
    • (1996) Free Radic Biol Med , vol.20 , pp. 707-727
    • Berliner, J.A.1    Heinecke, J.W.2
  • 4
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-An inflammatory disease
    • Ross R. Atherosclerosis-An inflammatory disease. N Engl J Med 1999;340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 5
    • 0032518420 scopus 로고    scopus 로고
    • A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice
    • Boisvert WA, Santiago R, Curtiss LK, Terkeltaub RA. A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice. J Clin Invest 1998;101:353-363.
    • (1998) J Clin Invest , vol.101 , pp. 353-363
    • Boisvert, W.A.1    Santiago, R.2    Curtiss, L.K.3    Terkeltaub, R.A.4
  • 6
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice
    • Gu L, Okada Y, Clinton SK, Gerard C, Sukhova GK, Libby P, Rollins BJ. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell 1998;2:275-281.
    • (1998) Mol Cell , vol.2 , pp. 275-281
    • Gu, L.1    Okada, Y.2    Clinton, S.K.3    Gerard, C.4    Sukhova, G.K.5    Libby, P.6    Rollins, B.J.7
  • 8
    • 0036691048 scopus 로고    scopus 로고
    • Macrophage-specific expression of class A scavenger receptors in LDL receptor(-/-) mice decreases atherosclerosis and changes spleen morphology
    • Whitman SC, Rateri DL, Szilvassy SJ, Cornicelli JA, Daugherty A. Macrophage-specific expression of class A scavenger receptors in LDL receptor(-/-) mice decreases atherosclerosis and changes spleen morphology. J Lipid Res 2002;43:1201-1208.
    • (2002) J Lipid Res , vol.43 , pp. 1201-1208
    • Whitman, S.C.1    Rateri, D.L.2    Szilvassy, S.J.3    Cornicelli, J.A.4    Daugherty, A.5
  • 9
    • 79151484549 scopus 로고    scopus 로고
    • Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: A crucial role for Krüppel-like factor 2
    • van Tits LJH, Stienstra R, van Lent PL, Netea MG, Joosten LAB, Stalenhoef AFH. Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: A crucial role for Krüppel-like factor 2. Atherosclerosis 2011;214:345-349.
    • (2011) Atherosclerosis , vol.214 , pp. 345-349
    • Van Tits, L.J.H.1    Stienstra, R.2    Van Lent, P.L.3    Netea, M.G.4    Joosten, L.A.B.5    Stalenhoef, A.F.H.6
  • 10
    • 2542533762 scopus 로고    scopus 로고
    • Dual role of oxidized LDL on the NF-kappaB signaling pathway
    • Robbesyn F, Salvayre R, Negre-Salvayre A. Dual role of oxidized LDL on the NF-kappaB signaling pathway. Free Radic Res 2004;38:541-551.
    • (2004) Free Radic Res , vol.38 , pp. 541-551
    • Robbesyn, F.1    Salvayre, R.2    Negre-Salvayre, A.3
  • 11
    • 0037414088 scopus 로고    scopus 로고
    • Antioxidants, statins, and atherosclerosis
    • Gotto AM. Antioxidants, statins, and atherosclerosis. J Am Coll Cardiol 2003;41: 1205-1210.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1205-1210
    • Gotto, A.M.1
  • 12
    • 1442284302 scopus 로고    scopus 로고
    • Antioxidants and atherosclerosis
    • Niki E. Antioxidants and atherosclerosis. Biochem Soc Trans 2004;32:156-159.
    • (2004) Biochem Soc Trans , vol.32 , pp. 156-159
    • Niki, E.1
  • 13
    • 77952527791 scopus 로고    scopus 로고
    • Vitamin E and cardiovascular disease
    • Saremi A, Arora R. Vitamin E and cardiovascular disease. Am J Ther 2010;17:e56-e65.
    • (2010) Am J Ther , vol.17 , pp. e56-e65
    • Saremi, A.1    Arora, R.2
  • 14
    • 0037197722 scopus 로고    scopus 로고
    • Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?
    • Steinberg D, Witztum JL. Is the oxidative modification hypothesis relevant to human atherosclerosis?: Do the antioxidant trials conducted to date refute the hypothesis? Circulation 2002;105:2107-2111.
    • (2002) Circulation , vol.105 , pp. 2107-2111
    • Steinberg, D.1    Witztum, J.L.2
  • 15
    • 0030781227 scopus 로고    scopus 로고
    • Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysis
    • Kissner R, Nauser T, Bugnon P, Lye PG, Koppenol WH. Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysis. Chem Res Toxicol 1997;10:1285-1292.
    • (1997) Chem Res Toxicol , vol.10 , pp. 1285-1292
    • Kissner, R.1    Nauser, T.2    Bugnon, P.3    Lye, P.G.4    Koppenol, W.H.5
  • 17
    • 79958253666 scopus 로고    scopus 로고
    • Polymer-based therapeutics: Nanoassemblies and nanoparticles for management of atherosclerosis
    • Wiley
    • Lewis DR, Kamisoglu K, York AW, Moghe PV. Polymer-based therapeutics: nanoassemblies and nanoparticles for management of atherosclerosis. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2011;3:400-420.
    • (2011) Interdiscip Rev Nanomed Nanobiotechnol , vol.3 , pp. 400-420
    • Lewis, D.R.1    Kamisoglu, K.2    York, A.W.3    Moghe, P.V.4
  • 18
    • 33745619265 scopus 로고    scopus 로고
    • Engineered polymeric nanoparticles for receptor-Targeted blockage of oxidized low density lipoprotein uptake and atherogenesis in macrophages
    • Chnari E, Nikitczuk JS, Wang J, Uhrich KE, Moghe PV. Engineered polymeric nanoparticles for receptor-Targeted blockage of oxidized low density lipoprotein uptake and atherogenesis in macrophages. Biomacromolecules 2006;7:1796-1805.
    • (2006) Biomacromolecules , vol.7 , pp. 1796-1805
    • Chnari, E.1    Nikitczuk, J.S.2    Wang, J.3    Uhrich, K.E.4    Moghe, P.V.5
  • 19
    • 67049117928 scopus 로고    scopus 로고
    • Structure2activity relations of nanolipoblockers with the atherogenic domain of human macrophage scavenger receptor A
    • Plourde NM, Kortagere S, WelshW, Moghe PV. Structure2activity relations of nanolipoblockers with the atherogenic domain of human macrophage scavenger receptor A. Biomacromolecules 2009;10:1381-1391.
    • (2009) Biomacromolecules , vol.10 , pp. 1381-1391
    • Plourde, N.M.1    Kortagere, S.2    Welsh, W.3    Moghe, P.V.4
  • 20
    • 84873960992 scopus 로고    scopus 로고
    • Carbohydrate composition of amphiphilic macromolecules influences physicochemical properties and binding to atherogenic scavenger receptor A
    • Hehir S, Plourde NM, Gu L, Poree DE, Welsh WJ, Moghe PV, Uhrich KE. Carbohydrate composition of amphiphilic macromolecules influences physicochemical properties and binding to atherogenic scavenger receptor A. Acta Biomater 2012;8:3956-3962.
    • (2012) Acta Biomater , vol.8 , pp. 3956-3962
    • Hehir, S.1    Plourde, N.M.2    Gu, L.3    Poree, D.E.4    Welsh, W.J.5    Moghe, P.V.6    Uhrich, K.E.7
  • 22
    • 77956642537 scopus 로고    scopus 로고
    • Controllable inhibition of cellular uptake of oxidized low-density lipoprotein: Structure-function relationships for nanoscale amphiphilic polymers
    • IversonNM, Sparks SM, Demirdirek B, Uhrich KE, Moghe PV. Controllable inhibition of cellular uptake of oxidized low-density lipoprotein: structure-function relationships for nanoscale amphiphilic polymers. Acta Biomater 2010;6:3081-3091.
    • (2010) Acta Biomater , vol.6 , pp. 3081-3091
    • Iverson, N.M.1    Sparks, S.M.2    Demirdirek, B.3    Uhrich, K.E.4    Moghe, P.V.5
  • 23
    • 84856472300 scopus 로고    scopus 로고
    • Kinetically assembled nanoparticles of bioactive macromolecules exhibit enhanced stability and cell-Targeted biological efficacy
    • York AW, Zablocki KR, Lewis DR, Gu L, Uhrich KE, Prudhomme RK, Moghe PV. Kinetically assembled nanoparticles of bioactive macromolecules exhibit enhanced stability and cell-Targeted biological efficacy. Adv Mater 2012;24:733-739.
    • (2012) Adv Mater , vol.24 , pp. 733-739
    • York, A.W.1    Zablocki, K.R.2    Lewis, D.R.3    Gu, L.4    Uhrich, K.E.5    Prudhomme, R.K.6    Moghe, P.V.7
  • 24
    • 0141927375 scopus 로고    scopus 로고
    • Flash nanoprecipitation of organic actives and block copolymers using a confined impinging jets mixer
    • Johnson BK, Prudhomme RK. Flash nanoprecipitation of organic actives and block copolymers using a confined impinging jets mixer. Aust J Chem 2003;56:1021-1024.
    • (2003) Aust J Chem , vol.56 , pp. 1021-1024
    • Johnson, B.K.1    Prudhomme, R.K.2
  • 25
    • 68249096676 scopus 로고    scopus 로고
    • Formulation and stability of itraconazole and odanacatib nanoparticles: Governing physical parameters
    • Kumar V, Wang L, Riebe M, Tung H-H, Prudhomme RK. Formulation and stability of itraconazole and odanacatib nanoparticles: governing physical parameters. Mol Pharm 2009;6:1118-1124.
    • (2009) Mol Pharm , vol.6 , pp. 1118-1124
    • Kumar, V.1    Wang, L.2    Riebe, M.3    Tung, H.-H.4    Prudhomme, R.K.5
  • 26
    • 38349183245 scopus 로고    scopus 로고
    • Composite block copolymer stabilized nanoparticles: Simultaneous encapsulation of organic actives and inorganic nanostructures
    • Gindy ME, Panagiotopoulos AZ, Prudhomme RK. Composite block copolymer stabilized nanoparticles: simultaneous encapsulation of organic actives and inorganic nanostructures. Langmuir 2007;24:83-90.
    • (2007) Langmuir , vol.24 , pp. 83-90
    • Gindy, M.E.1    Panagiotopoulos, A.Z.2    Prudhomme, R.K.3
  • 27
    • 84905472274 scopus 로고    scopus 로고
    • Amphiphilic nanoparticles repress macrophage atherogenesis: Novel core/shell designs for scavenger receptor targeting and down-regulation
    • Petersen LK, York AW, Lewis DR, Ahuja S, Uhrich KE, Prudhomme RK, Moghe PV. Amphiphilic nanoparticles repress macrophage atherogenesis: novel core/shell designs for scavenger receptor targeting and down-regulation. Mol Pharm 2014;11:2815-2824.
    • (2014) Mol Pharm , vol.11 , pp. 2815-2824
    • Petersen, L.K.1    York, A.W.2    Lewis, D.R.3    Ahuja, S.4    Uhrich, K.E.5    Prudhomme, R.K.6    Moghe, P.V.7
  • 30
    • 0026069562 scopus 로고
    • Role of Vitamin E in preventing the oxidation of low-density lipoprotein
    • Esterbauer H, Dieber-Rotheneder M, Striegl G, Waeg G. Role of vitamin E in preventing the oxidation of low-density lipoprotein. Am J Clin Nutr 1991;53:314S-321S.
    • (1991) Am J Clin Nutr , vol.53 , pp. 314S-321S
    • Esterbauer, H.1    Dieber-Rotheneder, M.2    Striegl, G.3    Waeg, G.4
  • 31
    • 0037087203 scopus 로고    scopus 로고
    • Mechanism of Vitamin E inhibition of cyclooxygenase activity in macrophages from old mice: Role of peroxynitrite
    • Beharka AA, Wu D, Serafini M, Meydani SN. Mechanism of vitamin E inhibition of cyclooxygenase activity in macrophages from old mice: role of peroxynitrite. Free Radic Biol Med 2002;32:503-511.
    • (2002) Free Radic Biol Med , vol.32 , pp. 503-511
    • Beharka, A.A.1    Wu, D.2    Serafini, M.3    Meydani, S.N.4
  • 32
    • 5644223313 scopus 로고    scopus 로고
    • Vitamin E supplementation suppresses macrophage accumulation and endothelial cell expression of adhesion molecules in the aorta of hypercholesterolemic rabbits
    • Koga T, Kwan P, Zubik L, Ameho C, Smith D, Meydani M. Vitamin E supplementation suppresses macrophage accumulation and endothelial cell expression of adhesion molecules in the aorta of hypercholesterolemic rabbits. Atherosclerosis 2004;176: 265-272.
    • (2004) Atherosclerosis , vol.176 , pp. 265-272
    • Koga, T.1    Kwan, P.2    Zubik, L.3    Ameho, C.4    Smith, D.5    Meydani, M.6
  • 33
    • 0442326635 scopus 로고    scopus 로고
    • Amphiphilic scorpion-like macromolecules:-design synthesis and characterization
    • Tian L, Yam L, Zhou N, Tat H, Uhrich KE. Amphiphilic scorpion-like macromolecules:-design, synthesis, and characterization. Macromolecules 2004;37:538-543.
    • (2004) Macromolecules , vol.37 , pp. 538-543
    • Tian, L.1    Yam, L.2    Zhou, N.3    Tat, H.4    Uhrich, K.E.5
  • 34
    • 43049174741 scopus 로고    scopus 로고
    • Mixing in a multi-inlet vortex mixer (MIVM) for flash nano-precipitation
    • Liu Y, Cheng C, Liu Y, Prudhomme RK, Fox RO. Mixing in a multi-inlet vortex mixer (MIVM) for flash nano-precipitation. Chem Eng Sci 2008;63:2829-2842.
    • (2008) Chem Eng Sci , vol.63 , pp. 2829-2842
    • Liu, Y.1    Cheng, C.2    Liu, Y.3    Prudhomme, R.K.4    Fox, R.O.5
  • 35
    • 84881591156 scopus 로고    scopus 로고
    • Coarse grained molecular dynamics of engineered macromolecules for the inhibition of oxidized lowdensity lipoprotein uptake by macrophage scavenger receptors
    • Tomasini MD, Zablocki K, Petersen LK, Moghe PV, Tomassone MS. Coarse grained molecular dynamics of engineered macromolecules for the inhibition of oxidized lowdensity lipoprotein uptake by macrophage scavenger receptors. Biomacromolecules 2013;14:2499-2509.
    • (2013) Biomacromolecules , vol.14 , pp. 2499-2509
    • Tomasini, M.D.1    Zablocki, K.2    Petersen, L.K.3    Moghe, P.V.4    Tomassone, M.S.5
  • 37
    • 70349581878 scopus 로고    scopus 로고
    • Macrophage diversity and polarization in atherosclerosis: A question of balance
    • Mantovani A, Garlanda C, Locati M. Macrophage diversity and polarization in atherosclerosis: A question of balance. Arterioscler Thromb Vasc Biol 2009;29:1419-1423.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1419-1423
    • Mantovani, A.1    Garlanda, C.2    Locati, M.3
  • 38
    • 33846352854 scopus 로고    scopus 로고
    • New vistas on macrophage differentiation and activation
    • Mantovani A, Sica A, Locati M. New vistas on macrophage differentiation and activation. Eur J Immunol 2007;37:14-16.
    • (2007) Eur J Immunol , vol.37 , pp. 14-16
    • Mantovani, A.1    Sica, A.2    Locati, M.3
  • 42
    • 0035884016 scopus 로고    scopus 로고
    • Size-dependent proinflammatory effects of ultrafine polystyrene particles: A role for surface area and oxidative stress in the enhanced activity of ultrafines
    • Brown DM, Wilson MR, MacNeeW, Stone V, Donaldson K. Size-dependent proinflammatory effects of ultrafine polystyrene particles: A role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicol Appl Pharmacol 2001;175:191-199.
    • (2001) Toxicol Appl Pharmacol , vol.175 , pp. 191-199
    • Brown, D.M.1    Wilson, M.R.2    MacNee, W.3    Stone, V.4    Donaldson, K.5
  • 44
    • 6344253331 scopus 로고    scopus 로고
    • Capacity of human monocytes to phagocytose approved iron oxide MR contrast agents in vitro
    • Metz S, Bonaterra G, Rudelius M, Settles M, Rummeny E, Daldrup-Link H. Capacity of human monocytes to phagocytose approved iron oxide MR contrast agents in vitro. Eur Radiol 2004;14:1851-1858.
    • (2004) Eur Radiol , vol.14 , pp. 1851-1858
    • Metz, S.1    Bonaterra, G.2    Rudelius, M.3    Settles, M.4    Rummeny, E.5    Daldrup-Link, H.6
  • 46
    • 33645891172 scopus 로고    scopus 로고
    • Cytokines in atherosclerosis: Pathogenic and regulatory pathways
    • Tedgui A, Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev 2006;86:515-581.
    • (2006) Physiol Rev , vol.86 , pp. 515-581
    • Tedgui, A.1    Mallat, Z.2
  • 48
    • 11844262719 scopus 로고    scopus 로고
    • Macrophage activation in atherosclerosis: Pathogenesis and pharmacology of plaque rupture
    • Boyle JJ. Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque rupture. Curr Vasc Pharmacol 2005;3:63-68.
    • (2005) Curr Vasc Pharmacol , vol.3 , pp. 63-68
    • Boyle, J.J.1
  • 50
    • 0021172883 scopus 로고
    • Vitamin E is delivered to cells via the high affinity receptor for low-density lipoprotein
    • Traber MG, Kayden HJ. Vitamin E is delivered to cells via the high affinity receptor for low-density lipoprotein. Am J Clin Nutr 1984;40:747-751.
    • (1984) Am J Clin Nutr , vol.40 , pp. 747-751
    • Traber, M.G.1    Kayden, H.J.2
  • 51
    • 80052761810 scopus 로고    scopus 로고
    • Macrophage polarization in metabolic disorders: Functions and regulation
    • Chinetti-Gbaguidi G, Staels B. Macrophage polarization in metabolic disorders: functions and regulation. Curr Opin Lipidol 2011;22:365-372.
    • (2011) Curr Opin Lipidol , vol.22 , pp. 365-372
    • Chinetti-Gbaguidi, G.1    Staels, B.2
  • 53
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003;3: 23-35.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 54
    • 0036920110 scopus 로고    scopus 로고
    • Oxidized LDL-induced smooth muscle cell proliferation involves the EGF receptor/PI-3 kinase/Akt and the sphingolipid signaling pathways
    • Auge N, Garcia V, Maupas-Schwalm F, Levade T, Salvayre R, Negre-Salvayre A. Oxidized LDL-induced smooth muscle cell proliferation involves the EGF receptor/PI-3 kinase/Akt and the sphingolipid signaling pathways. Arterioscler Thromb Vasc Biol 2002;22:1990-1995.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1990-1995
    • Auge, N.1    Garcia, V.2    Maupas-Schwalm, F.3    Levade, T.4    Salvayre, R.5    Negre-Salvayre, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.