Coarse grained molecular dynamics of engineered macromolecules for the inhibition of oxidized low-density lipoprotein uptake by macrophage scavenger receptors

Biomacromolecules

Volumn 14, Issue 8, 2013, Pages 2499-2509

  Tomasini, Michael D ^a   Zablocki, Kyle ^a   Petersen, Latrisha K ^a   Moghe, Prabhas V ^a,b   Tomassone, M Silvina ^b  

^a RUTGERS UNIVERSITY   (United States)

^b The State University of New Jersey   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL UPTAKES; COARSE GRAINED MODELS; COARSE-GRAINED MOLECULAR DYNAMICS; MOLECULAR CHARGE; NUMBER OF CONTACTS; OXIDIZED LOW-DENSITY LIPOPROTEINS; POLYETHYLENE GLYCOL (PEG); SCAVENGER RECEPTOR;

AGGREGATES; LIPOPROTEINS; MACROMOLECULES; MICELLES; MOLECULAR DYNAMICS;

MACROPHAGES;

ANTILIPEMIC AGENT; NANOLIPOBLOCKER; OXIDIZED LOW DENSITY LIPOPROTEIN; SCAVENGER RECEPTOR A; UNCLASSIFIED DRUG; ANTIMETABOLITE; GALACTARIC ACID; LOW DENSITY LIPOPROTEIN; MACROGOL DERIVATIVE; MICELLE; PROTEIN BINDING; SUGAR ACID;

ARTICLE; ATHEROSCLEROSIS; BINDING SITE; CONCENTRATION RESPONSE; DRUG RECEPTOR BINDING; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIPID TRANSPORT; MACROMOLECULE; MACROPHAGE; MICELLIZATION; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; CONFORMATION; DRUG EFFECTS; DRUG SCREENING; METABOLISM; MICELLE; SYNTHESIS;

ANTIMETABOLITES; BINDING SITES; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; HUMANS; LIPOPROTEINS, LDL; MACROPHAGES; MICELLES; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; POLYETHYLENE GLYCOLS; PROTEIN BINDING; SCAVENGER RECEPTORS, CLASS A; SUGAR ACIDS;

EID: 84881591156     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm301764x     Document Type: Article

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