-
2
-
-
33745189196
-
Hyperpolarization- activated cation channels in fast-spiking interneurons of rat hippocampus
-
Aponte Y, Lien CC, Reisinger E, Jonas P. 2006. Hyperpolarization- activated cation channels in fast-spiking interneurons of rat hippocampus. J Physiol 574: 229–243.
-
(2006)
J Physiol
, vol.574
, pp. 229-243
-
-
Aponte, Y.1
Lien, C.C.2
Reisinger, E.3
Jonas, P.4
-
3
-
-
42349085463
-
Plasticity of intrinsic neuronal properties in CNS disorders
-
Beck H, Yaari Y. 2008. Plasticity of intrinsic neuronal properties in CNS disorders. Nat Rev Neurosci 9: 357–369.
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 357-369
-
-
Beck, H.1
Yaari, Y.2
-
4
-
-
84954358121
-
Hyperpolarization activated cyclic-nucleotide gated (HCN) channels in developing neuronal networks
-
Bender RA, Baram TZ. 2008. Hyperpolarization activated cyclic-nucleotide gated (HCN) channels in developing neuronal networks. Prog Neurobiol 86: 129–140.
-
(2008)
Prog Neurobiol
, vol.86
, pp. 129-140
-
-
Bender, R.A.1
Baram, T.Z.2
-
5
-
-
0042133339
-
Enhanced expression of a specific hyperpolarization-activated cyclic nucleotidegated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus
-
Bender RA, Soleymani SV, Brewster AL, Nguyen ST, Beck H, Mathern GW, Baram TZ. 2003. Enhanced expression of a specific hyperpolarization-activated cyclic nucleotidegated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus. J Neurosci 23: 6826–6836.
-
(2003)
J Neurosci
, vol.23
, pp. 6826-6836
-
-
Bender, R.A.1
Soleymani, S.V.2
Brewster, A.L.3
Nguyen, S.T.4
Beck, H.5
Mathern, G.W.6
Baram, T.Z.7
-
6
-
-
34247473998
-
Localization of HCN1 channels to presynaptic compartments: Novel plasticity that may contribute to hippocampal maturation
-
Bender RA, Kirschstein T, Kretz O, Brewster AL, Richichi C, Ruschenschmidt C, Shigemoto R, Beck H, Frotscher M, Baram TZ. 2007. Localization of HCN1 channels to presynaptic compartments: Novel plasticity that may contribute to hippocampal maturation. J Neurosci 27: 4697–4706.
-
(2007)
J Neurosci
, vol.27
, pp. 4697-4706
-
-
Bender, R.A.1
Kirschstein, T.2
Kretz, O.3
Brewster, A.L.4
Richichi, C.5
Ruschenschmidt, C.6
Shigemoto, R.7
Beck, H.8
Frotscher, M.9
Baram, T.Z.10
-
7
-
-
0035128287
-
High Ih channel density in the distal apical dendrite of layer V pyramidal cells increases bidirectional attenuation of EPSPs
-
Berger T, Larkum ME, Luscher HR. 2001. High Ih channel density in the distal apical dendrite of layer V pyramidal cells increases bidirectional attenuation of EPSPs. J Neurophysiol 85: 855–868.
-
(2001)
J Neurophysiol
, vol.85
, pp. 855-868
-
-
Berger, T.1
Larkum, M.E.2
Luscher, H.R.3
-
8
-
-
0142027016
-
Hyperpolarizationactivated current Ih disconnects somatic and dendritic spike initiation zones in layer V pyramidal neurons
-
Berger T, Senn W, Luscher HR. 2003. Hyperpolarizationactivated current Ih disconnects somatic and dendritic spike initiation zones in layer V pyramidal neurons. J Neurophysiol 90: 2428–2437.
-
(2003)
J Neurophysiol
, vol.90
, pp. 2428-2437
-
-
Berger, T.1
Senn, W.2
Luscher, H.R.3
-
9
-
-
67651030760
-
Hyperpolarization- activated cation channels: From genes to function
-
Biel M, Wahl-Schott C, Michalakis S, Zong X. 2009. Hyperpolarization- activated cation channels: From genes to function. Physiol Rev 89: 847–885.
-
(2009)
Physiol Rev
, vol.89
, pp. 847-885
-
-
Biel, M.1
Wahl-Schott, C.2
Michalakis, S.3
Zong, X.4
-
10
-
-
0036616875
-
Developmental febrile seizures modulate hippocampal gene expression of hyperpolarization- activated channels in an isoform- and cell-specific manner
-
Brewster A, Bender RA, Chen Y, Dube C, Eghbal-Ahmadi M, Baram TZ. 2002. Developmental febrile seizures modulate hippocampal gene expression of hyperpolarization- activated channels in an isoform- and cell-specific manner. J Neurosci 22: 4591–4599.
-
(2002)
J Neurosci
, vol.22
, pp. 4591-4599
-
-
Brewster, A.1
Bender, R.A.2
Chen, Y.3
Dube, C.4
Eghbal-Ahmadi, M.5
Baram, T.Z.6
-
11
-
-
17444429283
-
Formation of heteromeric hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the hippocampus is regulated by developmental seizures
-
Brewster AL, Bernard JA, Gall CM, Baram TZ. 2005. Formation of heteromeric hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the hippocampus is regulated by developmental seizures. Neurobiol Dis 19: 200–207.
-
(2005)
Neurobiol Dis
, vol.19
, pp. 200-207
-
-
Brewster, A.L.1
Bernard, J.A.2
Gall, C.M.3
Baram, T.Z.4
-
12
-
-
85083610343
-
HCN1-deficient mice: Functional and molecular characterization provides insight into cell-specific roles of HCN channels in hippocampal network excitability
-
Program 334.6, Atlanta
-
Brewster AL, Dube CM, Bender RA, Patel N, Lee M, Ring A, Baram TZ. 2006. HCN1-deficient mice: Functional and molecular characterization provides insight into cell-specific roles of HCN channels in hippocampal network excitability. In Annual Meeting of the Society for Neuroscience, Program 334.6, Atlanta.
-
(2006)
Annual Meeting of the Society for Neuroscience
-
-
Brewster, A.L.1
Dube, C.M.2
Bender, R.A.3
Patel, N.4
Lee, M.5
Ring, A.6
Baram, T.Z.7
-
13
-
-
33846942645
-
Quantitative analysis and subcellular distribution of mRNA and protein expression of the hyperpolarization- activated cyclic nucleotide-gated channels throughout development in rat hippocampus
-
Brewster AL, Chen Y, Bender RA, Yeh A, Shigemoto R, Baram TZ. 2007. Quantitative analysis and subcellular distribution of mRNA and protein expression of the hyperpolarization- activated cyclic nucleotide-gated channels throughout development in rat hippocampus. Cereb Cortex 17: 702–712.
-
(2007)
Cereb Cortex
, vol.17
, pp. 702-712
-
-
Brewster, A.L.1
Chen, Y.2
Bender, R.A.3
Yeh, A.4
Shigemoto, R.5
Baram, T.Z.6
-
14
-
-
27344447273
-
Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy
-
Budde T, Caputi L, Kanyshkova T, Staak R, Abrahamczik C, Munsch T, Pape HC. 2005. Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy. J Neurosci 25: 9871–9882.
-
(2005)
J Neurosci
, vol.25
, pp. 9871-9882
-
-
Budde, T.1
Caputi, L.2
Kanyshkova, T.3
Staak, R.4
Abrahamczik, C.5
Munsch, T.6
Pape, H.C.7
-
15
-
-
7744241088
-
HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons
-
Chan CS, Shigemoto R, Mercer JN, Surmeier DJ. 2004. HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons. J Neurosci 24: 9921–9932.
-
(2004)
J Neurosci
, vol.24
, pp. 9921-9932
-
-
Chan, C.S.1
Shigemoto, R.2
Mercer, J.N.3
Surmeier, D.J.4
-
16
-
-
0035102720
-
Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability
-
Chen K, Aradi I, Thon N, Eghbal-Ahmadi M, Baram TZ, Soltesz I. 2001. Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability. Nat Med 7: 331–337.
-
(2001)
Nat Med
, vol.7
, pp. 331-337
-
-
Chen, K.1
Aradi, I.2
Thon, N.3
Eghbal-Ahmadi, M.4
Baram, T.Z.5
Soltesz, I.6
-
18
-
-
77951728544
-
Augmented currents of an HCN2 variant in patients with febrile seizure syndromes
-
Dibbens LM, Reid CA, Hodgson B, Thomas EA, Phillips AM, Gazina E, Cromer BA, Clarke AL, Baram TZ, Scheffer IE, et al. 2010. Augmented currents of an HCN2 variant in patients with febrile seizure syndromes. Ann Neurol 67: 542–546.
-
(2010)
Ann Neurol
, vol.67
, pp. 542-546
-
-
Dibbens, L.M.1
Reid, C.A.2
Hodgson, B.3
Thomas, E.A.4
Phillips, A.M.5
Gazina, E.6
Cromer, B.A.7
Clarke, A.L.8
Baram, T.Z.9
Scheffer, I.E.10
-
19
-
-
82555174709
-
Recessive loss-of-function mutation in the pacemaker HCN2 channel causing increased neuronal excitability in a patient with idiopathic generalized epilepsy
-
DiFrancesco JC, Barbuti A, Milanesi R, Coco S, Bucchi A, Bottelli G, Ferrarese C, Franceschetti S, Terragni B, Baruscotti M, et al. 2011. Recessive loss-of-function mutation in the pacemaker HCN2 channel causing increased neuronal excitability in a patient with idiopathic generalized epilepsy. J Neurosci 31: 17327–17337.
-
(2011)
J Neurosci
, vol.31
, pp. 17327-17337
-
-
Difrancesco, J.C.1
Barbuti, A.2
Milanesi, R.3
Coco, S.4
Bucchi, A.5
Bottelli, G.6
Ferrarese, C.7
Franceschetti, S.8
Terragni, B.9
Baruscotti, M.10
-
20
-
-
33645061779
-
Temporal lobe epilepsy after experimental prolonged febrile seizures: Prospective analysis
-
Dube C, Richichi C, Bender RA, Chung G, Litt B, Baram TZ. 2006. Temporal lobe epilepsy after experimental prolonged febrile seizures: Prospective analysis. Brain 129: 911–922.
-
(2006)
Brain
, vol.129
, pp. 911-922
-
-
Dube, C.1
Richichi, C.2
Bender, R.A.3
Chung, G.4
Litt, B.5
Baram, T.Z.6
-
21
-
-
0032508032
-
Molecular identification of a hyperpolarization-activated channel in sea urchin sperm
-
Gauss R, Seifert R, Kaupp UB. 1998. Molecular identification of a hyperpolarization-activated channel in sea urchin sperm. Nature 393: 583–587.
-
(1998)
Nature
, vol.393
, pp. 583-587
-
-
Gauss, R.1
Seifert, R.2
Kaupp, U.B.3
-
23
-
-
77954525641
-
Abnormal pyramidal cell morphology and HCN channel expression in cortical dysplasia
-
Hablitz JJ, Yang J. 2010. Abnormal pyramidal cell morphology and HCN channel expression in cortical dysplasia. Epilepsia 51: 52–55.
-
(2010)
Epilepsia
, vol.51
, pp. 52-55
-
-
Hablitz, J.J.1
Yang, J.2
-
24
-
-
79952025700
-
The cGMP-dependent protein kinase II is an inhibitory modulator of the hyperpolarization-activated HCN2 channel
-
Hammelmann V, Zong X, Hofmann F, Michalakis S, Biel M. 2011. The cGMP-dependent protein kinase II is an inhibitory modulator of the hyperpolarization-activated HCN2 channel. PLoS ONE 6: e17078.
-
(2011)
Plos ONE
, vol.6
-
-
Hammelmann, V.1
Zong, X.2
Hofmann, F.3
Michalakis, S.4
Biel, M.5
-
25
-
-
77951495576
-
Evolutionary emergence of N-glycosylation as a variable promoter of HCN channel surface expression
-
Hegle AP, Nazzari H, Roth A, Angoli D, Accili EA. 2010. Evolutionary emergence of N-glycosylation as a variable promoter of HCN channel surface expression. AmJ Physiol Cell Physiol 298: C1066–1076.
-
(2010)
Amj Physiol Cell Physiol
, vol.298
-
-
Hegle, A.P.1
Nazzari, H.2
Roth, A.3
Angoli, D.4
Accili, E.A.5
-
26
-
-
69749094919
-
Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis
-
Huang Z, Walker MC, Shah MM. 2009. Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis. J Neurosci 29: 10979–10988.
-
(2009)
J Neurosci
, vol.29
, pp. 10979-10988
-
-
Huang, Z.1
Walker, M.C.2
Shah, M.M.3
-
28
-
-
84867617527
-
TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels
-
Huang Z, Lujan R, Martinez-Hernandez J, Lewis AS, Chetkovich DM, Shah MM. 2012. TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels. J Neurosci 32: 14835–14848.
-
(2012)
J Neurosci
, vol.32
, pp. 14835-14848
-
-
Huang, Z.1
Lujan, R.2
Martinez-Hernandez, J.3
Lewis, A.S.4
Chetkovich, D.M.5
Shah, M.M.6
-
29
-
-
84864831603
-
Thalamocortical circuits and excitability
-
Huguenard J. 2001. Thalamocortical circuits and excitability. Epilepsy Curr 1: 13.
-
(2001)
Epilepsy Curr
, vol.1
-
-
Huguenard, J.1
-
30
-
-
0033617416
-
Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node
-
Ishii TM, Takano M, Xie LH, Noma A, Ohmori H. 1999. Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node. J Biol Chem 274: 12835–12839.
-
(1999)
J Biol Chem
, vol.274
, pp. 12835-12839
-
-
Ishii, T.M.1
Takano, M.2
Xie, L.H.3
Noma, A.4
Ohmori, H.5
-
31
-
-
36348978149
-
Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy
-
Jung S, Jones TD, Lugo JN , Sheerin AH, Miller JW, D’Ambrosio R, Anderson AE, Poolos NP. 2007. Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy. J Neurosci 27: 13012–13021.
-
(2007)
J Neurosci
, vol.27
, pp. 13012-13021
-
-
Jung, S.1
Jones, T.D.2
Lugo, J.N.3
Sheerin, A.H.4
Miller, J.W.5
D’Ambrosio, R.6
Erson, A.E.7
Poolos, N.P.8
-
32
-
-
77952333161
-
Downregulation of dendritic HCN channel gating in epilepsy is mediated by altered phosphorylation signaling
-
Jung S, Bullis JB, Lau IH, Jones TD, Warner LN, Poolos NP. 2010. Downregulation of dendritic HCN channel gating in epilepsy is mediated by altered phosphorylation signaling. J Neurosci 30: 6678–6688.
-
(2010)
J Neurosci
, vol.30
, pp. 6678-6688
-
-
Jung, S.1
Bullis, J.B.2
Lau, I.H.3
Jones, T.D.4
Warner, L.N.5
Poolos, N.P.6
-
33
-
-
80053635605
-
Rapid loss of dendritic HCN channel expression in hippocampal pyramidal neurons following status epilepticus
-
Jung S, Warner LN, Pitsch J, Becker AJ, Poolos NP. 2011. Rapid loss of dendritic HCN channel expression in hippocampal pyramidal neurons following status epilepticus. J Neurosci 31: 14291–14295.
-
(2011)
J Neurosci
, vol.31
, pp. 14291-14295
-
-
Jung, S.1
Warner, L.N.2
Pitsch, J.3
Becker, A.J.4
Poolos, N.P.5
-
34
-
-
67650490686
-
Postnatal expression pattern of HCN channel isoforms in thalamic neurons: Relationship to maturation of thalamocortical oscillations
-
Kanyshkova T, Pawlowski M, Meuth P, Dube C, Bender RA, Brewster AL, Baumann A, Baram TZ, Pape HC, Budde T. 2009. Postnatal expression pattern of HCN channel isoforms in thalamic neurons: Relationship to maturation of thalamocortical oscillations. J Neurosci 29: 8847–8857.
-
(2009)
J Neurosci
, vol.29
, pp. 8847-8857
-
-
Kanyshkova, T.1
Pawlowski, M.2
Meuth, P.3
Dube, C.4
Bender, R.A.5
Brewster, A.L.6
Baumann, A.7
Baram, T.Z.8
Pape, H.C.9
Budde, T.10
-
35
-
-
33846200737
-
Inherited cortical HCN1 channel loss amplifies dendritic calcium electrogenesis and burst firing in a rat absence epilepsy model
-
Kole MH, Brauer AU, Stuart GJ. 2007. Inherited cortical HCN1 channel loss amplifies dendritic calcium electrogenesis and burst firing in a rat absence epilepsy model. J Physiol 578: 507–525.
-
(2007)
J Physiol
, vol.578
, pp. 507-525
-
-
Kole, M.H.1
Brauer, A.U.2
Stuart, G.J.3
-
36
-
-
33746889488
-
Functional stabilization of weakened thalamic pacemaker channel regulation in rat absence epilepsy
-
Kuisle M, Wanaverbecq N, Brewster AL, Frere SG, Pinault D, Baram TZ, Luthi A. 2006. Functional stabilization of weakened thalamic pacemaker channel regulation in rat absence epilepsy. J Physiol 575: 83–100.
-
(2006)
J Physiol
, vol.575
, pp. 83-100
-
-
Kuisle, M.1
Wanaverbecq, N.2
Brewster, A.L.3
Frere, S.G.4
Pinault, D.5
Baram, T.Z.6
Luthi, A.7
-
37
-
-
78751703303
-
HCNchannels in behavior and neurological disease: Too hyper or not active enough?
-
Lewis AS, Chetkovich DM. 2011.HCNchannels in behavior and neurological disease: Too hyper or not active enough? Mol Cell Neurosci 46: 357–367.
-
(2011)
Mol Cell Neurosci
, vol.46
, pp. 357-367
-
-
Lewis, A.S.1
Chetkovich, D.M.2
-
38
-
-
66049132379
-
Alternatively spliced isoforms of TRIP8b differentially control h channel trafficking and function
-
Lewis AS, Schwartz E, Chan CS, Noam Y, Shin M, Wadman WJ, Surmeier DJ, Baram TZ, Macdonald RL, Chetkovich DM. 2009. Alternatively spliced isoforms of TRIP8b differentially control h channel trafficking and function. J Neurosci 29: 6250–6265.
-
(2009)
J Neurosci
, vol.29
, pp. 6250-6265
-
-
Lewis, A.S.1
Schwartz, E.2
Chan, C.S.3
Noam, Y.4
Shin, M.5
Wadman, W.J.6
Surmeier, D.J.7
Baram, T.Z.8
Macdonald, R.L.9
Chetkovich, D.M.10
-
39
-
-
84863279803
-
Role of HCN channels in neuronal hyperexcitability after subarachnoid hemorrhage in rats
-
Li B, Luo C, Tang W, Chen Z, Li Q, Hu B, Lin J, Zhu G, Zhang JH, Feng H. 2012. Role of HCN channels in neuronal hyperexcitability after subarachnoid hemorrhage in rats. J Neurosci 32: 3164–3175.
-
(2012)
J Neurosci
, vol.32
, pp. 3164-3175
-
-
Li, B.1
Luo, C.2
Tang, W.3
Chen, Z.4
Li, Q.5
Hu, B.6
Lin, J.7
Zhu, G.8
Zhang, J.H.9
Feng, H.10
-
40
-
-
0036828965
-
Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites
-
Lorincz A, Notomi T, Tamas G, Shigemoto R, Nusser Z. 2002. Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites. Nat Neurosci 5: 1185–1193.
-
(2002)
Nat Neurosci
, vol.5
, pp. 1185-1193
-
-
Lorincz, A.1
Notomi, T.2
Tamas, G.3
Shigemoto, R.4
Nusser, Z.5
-
41
-
-
0032508040
-
A family of hyperpolarization-activated mammalian cation channels
-
Ludwig A, Zong X, Jeglitsch M, Hofmann F, Biel M. 1998. A family of hyperpolarization-activated mammalian cation channels. Nature 393: 587–591.
-
(1998)
Nature
, vol.393
, pp. 587-591
-
-
Ludwig, A.1
Zong, X.2
Jeglitsch, M.3
Hofmann, F.4
Biel, M.5
-
42
-
-
0037439203
-
Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2
-
Ludwig A, Budde T, Stieber J, Moosmang S, Wahl C, Holthoff K, Langebartels A, Wotjak C, Munsch T, Zong X, et al. 2003. Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2. EMBO J 22: 216–224.
-
(2003)
EMBO J
, vol.22
, pp. 216-224
-
-
Ludwig, A.1
Budde, T.2
Stieber, J.3
Moosmang, S.4
Wahl, C.5
Holthoff, K.6
Langebartels, A.7
Wotjak, C.8
Munsch, T.9
Zong, X.10
-
43
-
-
18844393688
-
Preferential localization of the hyperpolarization-activated cyclic nucleotide-gated cation channel subunit HCN1 in basket cell terminals of the rat cerebellum
-
Lujan R, Albasanz JL, Shigemoto R, Juiz JM. 2005. Preferential localization of the hyperpolarization-activated cyclic nucleotide-gated cation channel subunit HCN1 in basket cell terminals of the rat cerebellum. Eur J Neurosci 21: 2073–2082.
-
(2005)
Eur J Neurosci
, vol.21
, pp. 2073-2082
-
-
Lujan, R.1
Albasanz, J.L.2
Shigemoto, R.3
Juiz, J.M.4
-
44
-
-
0034930393
-
Contribution of the hyperpolarization-activated current (Ih) to membrane potential and GABA release in hippocampal interneurons
-
Lupica CR, Bell JA, Hoffman AF, Watson PL. 2001. Contribution of the hyperpolarization-activated current (Ih) to membrane potential and GABA release in hippocampal interneurons. J Neurophysiol 86: 261–268.
-
(2001)
J Neurophysiol
, vol.86
, pp. 261-268
-
-
Lupica, C.R.1
Bell, J.A.2
Hoffman, A.F.3
Watson, P.L.4
-
45
-
-
0029966978
-
The hyperpolarization-activated current (Ih) and its contribution to pacemaker activity in rat CA1 hippocampal stratum oriens-alveus interneurones
-
Maccaferri G, McBain CJ. 1996. The hyperpolarization-activated current (Ih) and its contribution to pacemaker activity in rat CA1 hippocampal stratum oriens-alveus interneurones. J Physiol 497: 119–130.
-
(1996)
J Physiol
, vol.497
, pp. 119-130
-
-
Maccaferri, G.1
McBain, C.J.2
-
46
-
-
0032190309
-
Dendritic hyperpolarization-activated currents modify the integrative properties of hippocampal CA1 pyramidal neurons
-
Magee JC. 1998. Dendritic hyperpolarization-activated currents modify the integrative properties of hippocampal CA1 pyramidal neurons. J Neurosci 18: 7613–7624.
-
(1998)
J Neurosci
, vol.18
, pp. 7613-7624
-
-
Magee, J.C.1
-
47
-
-
0033237837
-
Dendritic Ih normalizes temporal summation in hippocampal CA1 neurons
-
Magee JC. 1999. Dendritic Ih normalizes temporal summation in hippocampal CA1 neurons. Nat Neurosci 2: 848.
-
(1999)
Nat Neurosci
, vol.2
-
-
Magee, J.C.1
-
48
-
-
60849094368
-
Bernard C. 2009. H Channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy
-
Marcelin B, Chauviere L, Becker A, Migliore M, Esclapez M, Bernard C. 2009. h Channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy. Neurobiol Dis 33: 436–447.
-
Neurobiol Dis
, vol.33
, pp. 436-447
-
-
Marcelin, B.1
Chauviere, L.2
Becker, A.3
Migliore, M.4
Esclapez, M.5
-
49
-
-
80052587330
-
Neuronrestrictive silencer factor-mediated hyperpolarizationactivated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy
-
McClelland S, Flynn C, Dube C, Richichi C, Zha Q, Ghestem A, Esclapez M, Bernard C, Baram TZ. 2011. Neuronrestrictive silencer factor-mediated hyperpolarizationactivated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy. Ann Neurol 70: 454–464.
-
(2011)
Ann Neurol
, vol.70
, pp. 454-464
-
-
McClelland, S.1
Flynn, C.2
Dube, C.3
Richichi, C.4
Zha, Q.5
Ghestem, A.6
Esclapez, M.7
Bernard, C.8
Baram, T.Z.9
-
50
-
-
84929277598
-
The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes
-
McClelland S, Brennan GP, Dube C, Rajpara S, Iyer S, Richichi C, Bernard C, Baram TZ. 2014. The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes. eLife 3: e01267.
-
(2014)
Elife
, vol.3
-
-
McClelland, S.1
Brennan, G.P.2
Dube, C.3
Rajpara, S.4
Iyer, S.5
Richichi, C.6
Bernard, C.7
Baram, T.Z.8
-
51
-
-
0031057655
-
Sleep and arousal: Thalamocortical mechanisms
-
McCormick DA, Bal T. 1997. Sleep and arousal: Thalamocortical mechanisms. Annu Rev Neurosci 20: 185–215.
-
(1997)
Annu Rev Neurosci
, vol.20
, pp. 185-215
-
-
McCormick, D.A.1
Bal, T.2
-
52
-
-
84907313546
-
Cardiac arrhythmia induced by genetic silencing of “funny” (F) channels is rescued by GIRK4 inactivation
-
Mesirca P, Alig J, Torrente AG, Muller JC, Marger L, Rollin A, Marquilly C, Vincent A, Dubel S, Bidaud I, et al. 2014. Cardiac arrhythmia induced by genetic silencing of “funny” (f) channels is rescued by GIRK4 inactivation. Nat Commun 5: 4664.
-
(2014)
Nat Commun
, vol.5
-
-
Mesirca, P.1
Alig, J.2
Torrente, A.G.3
Muller, J.C.4
Marger, L.5
Rollin, A.6
Marquilly, C.7
Vincent, A.8
Dubel, S.9
Bidaud, I.10
-
53
-
-
0242353179
-
Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels
-
Much B, Wahl-Schott C, Zong X, Schneider A, Baumann L, Moosmang S, Ludwig A, Biel M. 2003. Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels. J Biol Chem 278: 43781–43786.
-
(2003)
J Biol Chem
, vol.278
, pp. 43781-43786
-
-
Much, B.1
Wahl-Schott, C.2
Zong, X.3
Schneider, A.4
Baumann, L.5
Moosmang, S.6
Ludwig, A.7
Biel, M.8
-
54
-
-
0033200069
-
Upregulation of the hyperpolarization- activated cation current in rat thalamic relay neurones by acetazolamide
-
Munsch T, Pape HC. 1999. Upregulation of the hyperpolarization- activated cation current in rat thalamic relay neurones by acetazolamide. J Physiol 519: 505–514.
-
(1999)
J Physiol
, vol.519
, pp. 505-514
-
-
Munsch, T.1
Pape, H.C.2
-
55
-
-
84891858655
-
Novel HCN2 mutation contributes to febrile seizures by shifting the channel’s kinetics in a temperature-dependent manner
-
Nakamura Y, Shi X, Numata T, Mori Y, Inoue R, Lossin C, Baram TZ, Hirose S. 2013. Novel HCN2 mutation contributes to febrile seizures by shifting the channel’s kinetics in a temperature-dependent manner. PLoS ONE 8: e80376.
-
(2013)
Plos ONE
, vol.8
-
-
Nakamura, Y.1
Shi, X.2
Numata, T.3
Mori, Y.4
Inoue, R.5
Lossin, C.6
Baram, T.Z.7
Hirose, S.8
-
56
-
-
84901670752
-
De novo mutations in HCN1 cause early infantile epileptic encephalopathy
-
Nava C, Dalle C, Rastetter A, Striano P, de Kovel CG, Nabbout R, Cances C, Ville D, Brilstra EH, Gobbi G, et al. 2014. De novo mutations in HCN1 cause early infantile epileptic encephalopathy. Nat Genet 46: 640–645.
-
(2014)
Nat Genet
, vol.46
, pp. 640-645
-
-
Nava, C.1
Dalle, C.2
Rastetter, A.3
Striano, P.4
De Kovel, C.G.5
Nabbout, R.6
Cances, C.7
Ville, D.8
Brilstra, E.H.9
Gobbi, G.10
-
57
-
-
77951982872
-
Trafficking and surface expression of hyperpolarization-activated cyclic nucleotide-gated channels in hippocampal neurons
-
Noam Y, Zha Q, Phan L, Wu RL, Chetkovich DM, Wadman WJ, Baram TZ. 2010. Trafficking and surface expression of hyperpolarization-activated cyclic nucleotide-gated channels in hippocampal neurons. J Biol Chem 285: 14724–14736.
-
(2010)
J Biol Chem
, vol.285
, pp. 14724-14736
-
-
Noam, Y.1
Zha, Q.2
Phan, L.3
Wu, R.L.4
Chetkovich, D.M.5
Wadman, W.J.6
Baram, T.Z.7
-
58
-
-
82455167477
-
Towards an integrated view of HCN channel role in epilepsy
-
Noam Y, Bernard C, Baram TZ. 2011. Towards an integrated view of HCN channel role in epilepsy. Curr Opin Neurobiol 21: 873–879.
-
(2011)
Curr Opin Neurobiol
, vol.21
, pp. 873-879
-
-
Noam, Y.1
Bernard, C.2
Baram, T.Z.3
-
59
-
-
84896869586
-
Filamin A promotes dynamin-dependent internalization of hyperpolarization- activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ih in hippocampal neurons
-
Noam Y, Ehrengruber MU, Koh A, Feyen P, Manders EM, Abbott GW, Wadman WJ, Baram TZ. 2014. Filamin A promotes dynamin-dependent internalization of hyperpolarization- activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ih in hippocampal neurons. J Biol Chem 289: 5889–5903.
-
(2014)
J Biol Chem
, vol.289
, pp. 5889-5903
-
-
Noam, Y.1
Ehrengruber, M.U.2
Koh, A.3
Feyen, P.4
Manders, E.M.5
Abbott, G.W.6
Wadman, W.J.7
Baram, T.Z.8
-
60
-
-
8844278361
-
A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons
-
Nolan MF, Malleret G, Dudman JT, Buhl DL, Santoro B, Gibbs E, Vronskaya S, Buzsaki G, Siegelbaum SA, Kandel ER, et al. 2004. A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons. Cell 119: 719–732.
-
(2004)
Cell
, vol.119
, pp. 719-732
-
-
Nolan, M.F.1
Malleret, G.2
Dudman, J.T.3
Buhl, D.L.4
Santoro, B.5
Gibbs, E.6
Vronskaya, S.7
Buzsaki, G.8
Siegelbaum, S.A.9
Kandel, E.R.10
-
61
-
-
1442300292
-
Immunohistochemical localization of Ih channel subunits, HCN1–4, in the rat brain
-
Notomi T, Shigemoto R. 2004. Immunohistochemical localization of Ih channel subunits, HCN1–4, in the rat brain. J Comp Neurol 471: 241–276.
-
(2004)
J Comp Neurol
, vol.471
, pp. 241-276
-
-
Notomi, T.1
Shigemoto, R.2
-
62
-
-
65349136418
-
Variability in the subcellular distribution of ion channels increases neuronal diversity
-
Nusser Z. 2009. Variability in the subcellular distribution of ion channels increases neuronal diversity. TrendsNeurosci 32: 267–274.
-
(2009)
Trendsneurosci
, vol.32
, pp. 267-274
-
-
Nusser, Z.1
-
63
-
-
72449151644
-
Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances Ih
-
Peng BW, Justice JA, Zhang K, He XH, Sanchez RM. 2010. Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances Ih. Neuropsychopharmacology 35: 464–472.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 464-472
-
-
Peng, B.W.1
Justice, J.A.2
Zhang, K.3
He, X.H.4
Sanchez, R.M.5
-
64
-
-
0036321057
-
Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites
-
Poolos NP, Migliore M, Johnston D. 2002. Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites. Nat Neurosci 5: 767–774.
-
(2002)
Nat Neurosci
, vol.5
, pp. 767-774
-
-
Poolos, N.P.1
Migliore, M.2
Johnston, D.3
-
65
-
-
58149235284
-
Decreases in HCN mRNA expression in the hippocampus after kindling and status epilepticus in adult rats
-
Powell KL, Ng C, O’Brien TJ, Xu SH, Williams DA, Foote SJ, Reid CA. 2008. Decreases in HCN mRNA expression in the hippocampus after kindling and status epilepticus in adult rats. Epilepsia 49: 1686–1695.
-
(2008)
Epilepsia
, vol.49
, pp. 1686-1695
-
-
Powell, K.L.1
Ng, C.2
O’Brien, T.J.3
Xu, S.H.4
Williams, D.A.5
Foote, S.J.6
Reid, C.A.7
-
66
-
-
0012457490
-
Hyperpolarization-activated cation currents: From molecules to physiological function
-
Robinson RB, Siegelbaum SA. 2003. Hyperpolarization-activated cation currents: From molecules to physiological function. Annu Rev Physiol 65: 453–480.
-
(2003)
Annu Rev Physiol
, vol.65
, pp. 453-480
-
-
Robinson, R.B.1
Siegelbaum, S.A.2
-
67
-
-
0141867836
-
The multiple personalities of hchannels
-
Santoro B, Baram TZ. 2003. The multiple personalities of hchannels. Trends Neurosci 26: 550–554.
-
(2003)
Trends Neurosci
, vol.26
, pp. 550-554
-
-
Santoro, B.1
Baram, T.Z.2
-
68
-
-
0031434001
-
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein,with homology to Eag and cyclic nucleotide-gated channels
-
Santoro B, Grant SG, Bartsch D, Kandel ER. 1997. Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein,with homology to Eag and cyclic nucleotide-gated channels. Proc Natl Acad Sci 94: 14815–14820.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 14815-14820
-
-
Santoro, B.1
Grant, S.G.2
Bartsch, D.3
Kandel, E.R.4
-
69
-
-
0032577559
-
Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain
-
Santoro B, Liu DT, Yao H, Bartsch D, Kandel ER, Siegelbaum SA, Tibbs GR. 1998. Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. Cell 93: 717–729.
-
(1998)
Cell
, vol.93
, pp. 717-729
-
-
Santoro, B.1
Liu, D.T.2
Yao, H.3
Bartsch, D.4
Kandel, E.R.5
Siegelbaum, S.A.6
Tibbs, G.R.7
-
70
-
-
9344265184
-
Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction
-
Santoro B, Wainger BJ, Siegelbaum SA. 2004. Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction. J Neurosci 24: 10750–10762.
-
(2004)
J Neurosci
, vol.24
, pp. 10750-10762
-
-
Santoro, B.1
Wainger, B.J.2
Siegelbaum, S.A.3
-
71
-
-
67249091362
-
TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain
-
Santoro B, Piskorowski RA, Pian P, Hu L, Liu H, Siegelbaum SA. 2009. TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain. Neuron 62: 802–813.
-
(2009)
Neuron
, vol.62
, pp. 802-813
-
-
Santoro, B.1
Piskorowski, R.A.2
Pian, P.3
Hu, L.4
Liu, H.5
Siegelbaum, S.A.6
-
72
-
-
77955327254
-
Increased seizure severity and seizure-related death in mice lacking HCN1 channels
-
Santoro B, Lee JY, Englot DJ, Gildersleeve S, Piskorowski RA, Siegelbaum SA, Winawer MR, Blumenfeld H. 2010. Increased seizure severity and seizure-related death in mice lacking HCN1 channels. Epilepsia 51: 1624–1627.
-
(2010)
Epilepsia
, vol.51
, pp. 1624-1627
-
-
Santoro, B.1
Lee, J.Y.2
Englot, D.J.3
Gildersleeve, S.4
Piskorowski, R.A.5
Siegelbaum, S.A.6
Winawer, M.R.7
Blumenfeld, H.8
-
73
-
-
7044222366
-
Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons
-
Shah MM, Anderson AE, Leung V, Lin X, Johnston D. 2004. Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons. Neuron 44: 495–508.
-
(2004)
Neuron
, vol.44
, pp. 495-508
-
-
Shah, M.M.1
Erson, A.E.2
Leung, V.3
Lin, X.4
Johnston, D.5
-
74
-
-
0032525113
-
Determinants of voltage attenuation in neocortical pyramidal neuron dendrites
-
Stuart G, Spruston N. 1998. Determinants of voltage attenuation in neocortical pyramidal neuron dendrites. J Neurosci 18: 3501–3510.
-
(1998)
J Neurosci
, vol.18
, pp. 3501-3510
-
-
Stuart, G.1
Spruston, N.2
-
75
-
-
0037320683
-
Gabapentin increases the hyperpolarization-activated cation current Ih in rat CA1 pyramidal cells
-
Surges R, Freiman TM, Feuerstein TJ. 2003. Gabapentin increases the hyperpolarization-activated cation current Ih in rat CA1 pyramidal cells. Epilepsia 44: 150–156.
-
(2003)
Epilepsia
, vol.44
, pp. 150-156
-
-
Surges, R.1
Freiman, T.M.2
Feuerstein, T.J.3
-
76
-
-
84859110634
-
Hyperpolarization- activated cation current Ih of dentate gyrus granule cells is upregulated in human and rat temporal lobe epilepsy
-
Surges R, Kukley M, Brewster A, Ruschenschmidt C, Schramm J, Baram TZ, Beck H, Dietrich D. 2012. Hyperpolarization- activated cation current Ih of dentate gyrus granule cells is upregulated in human and rat temporal lobe epilepsy. Biochem Biophys Res Commun 420: 156–160.
-
(2012)
Biochem Biophys Res Commun
, vol.420
, pp. 156-160
-
-
Surges, R.1
Kukley, M.2
Brewster, A.3
Ruschenschmidt, C.4
Schramm, J.5
Baram, T.Z.6
Beck, H.7
Dietrich, D.8
-
77
-
-
36549022629
-
Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy
-
Tang B, Sander T, Craven KB, Hempelmann A, Escayg A. 2008.Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy. Neurobiol Dis 29: 59–70.
-
(2008)
Neurobiol Dis
, vol.29
, pp. 59-70
-
-
Tang, B.1
Sander, T.2
Craven, K.B.3
Hempelmann, A.4
Escayg, A.5
-
78
-
-
37049032338
-
HCN1 channels constrain synaptically evoked Ca2+ spikes in distal dendrites ofCA1 pyramidal neurons
-
2+ spikes in distal dendrites ofCA1 pyramidal neurons. Neuron 56: 1076–1089.
-
(2007)
Neuron
, vol.56
, pp. 1076-1089
-
-
Tsay, D.1
Dudman, J.T.2
Siegelbaum, S.A.3
-
79
-
-
0037421670
-
Bidirectional changes in spatial dendritic integration accompanying long-term synaptic modifications
-
Wang Z, Xu NL, Wu CP, Duan S, Poo MM. 2003. Bidirectional changes in spatial dendritic integration accompanying long-term synaptic modifications. Neuron 37: 463–472.
-
(2003)
Neuron
, vol.37
, pp. 463-472
-
-
Wang, Z.1
Xu, N.L.2
Wu, C.P.3
Duan, S.4
Poo, M.M.5
-
80
-
-
34147105096
-
A2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex
-
Wang M, Ramos BP, Paspalas CD, Shu Y, Simen A, Duque A, Vijayraghavan S, Brennan A, Dudley A, Nou E, et al. 2007. a2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129: 397–410.
-
Cell
, vol.129
, pp. 397-410
-
-
Wang, M.1
Ramos, B.P.2
Paspalas, C.D.3
Shu, Y.4
Simen, A.5
Duque, A.6
Vijayraghavan, S.7
Brennan, A.8
Dudley, A.9
Nou, E.10
-
81
-
-
77749270482
-
Hyperpolarization-activated cation currents in human epileptogenic neocortex
-
Wierschke S, Lehmann TN, Dehnicke C, Horn P, Nitsch R, Deisz RA. 2010. Hyperpolarization-activated cation currents in human epileptogenic neocortex. Epilepsia 51: 404–414.
-
(2010)
Epilepsia
, vol.51
, pp. 404-414
-
-
Wierschke, S.1
Lehmann, T.N.2
Dehnicke, C.3
Horn, P.4
Nitsch, R.5
Deisz, R.A.6
-
82
-
-
84857408970
-
Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms
-
Wilkars W, Liu Z, Lewis AS, Stoub TR, Ramos EM, Brandt N, Nicholson DA, Chetkovich DM, Bender RA. 2012. Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms. PLoS ONE 7: e32181.
-
(2012)
Plos ONE
, vol.7
-
-
Wilkars, W.1
Liu, Z.2
Lewis, A.S.3
Stoub, T.R.4
Ramos, E.M.5
Brandt, N.6
Nicholson, D.A.7
Chetkovich, D.M.8
Bender, R.A.9
-
83
-
-
60849133327
-
Development of spontaneous recurrent seizures after kainate-induced status epilepticus
-
Williams PA, White AM, Clark S, Ferraro DJ, Swiercz W, Staley KJ, Dudek FE. 2009. Development of spontaneous recurrent seizures after kainate-induced status epilepticus. J Neurosci 29: 2103–2112.
-
(2009)
J Neurosci
, vol.29
, pp. 2103-2112
-
-
Williams, P.A.1
White, A.M.2
Clark, S.3
Ferraro, D.J.4
Swiercz, W.5
Staley, K.J.6
Dudek, F.E.7
-
84
-
-
84933672908
-
Protein kinase C bidirectionally modulates Ih and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel surface expression in hippocampal pyramidal neurons
-
Williams AD, Jung S, Poolos NP. 2015. Protein kinase C bidirectionally modulates Ih and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel surface expression in hippocampal pyramidal neurons. J Physiol 593: 2779–2792.
-
(2015)
J Physiol
, vol.593
, pp. 2779-2792
-
-
Williams, A.D.1
Jung, S.2
Poolos, N.P.3
-
85
-
-
34547905012
-
Dendritic HCN2 channels constrain glutamate- driven excitability in reticular thalamic neurons
-
Ying SW, Jia F, Abbas SY, Hofmann F, Ludwig A, Goldstein PA. 2007. Dendritic HCN2 channels constrain glutamate- driven excitability in reticular thalamic neurons. J Neurosci 27: 8719–8732.
-
(2007)
J Neurosci
, vol.27
, pp. 8719-8732
-
-
Ying, S.W.1
Jia, F.2
Abbas, S.Y.3
Hofmann, F.4
Ludwig, A.5
Goldstein, P.A.6
-
86
-
-
41149176443
-
Activity-dependent heteromerization of the hyperpolarization- activated, cyclic-nucleotide gated (HCN) channels: Role of N-linked glycosylation
-
Zha Q, Brewster AL, Richichi C, Bender RA, Baram TZ. 2008. Activity-dependent heteromerization of the hyperpolarization- activated, cyclic-nucleotide gated (HCN) channels: Role of N-linked glycosylation. J Neurochem 105: 68–77.
-
(2008)
J Neurochem
, vol.105
, pp. 68-77
-
-
Zha, Q.1
Brewster, A.L.2
Richichi, C.3
Bender, R.A.4
Baram, T.Z.5
-
87
-
-
33744493680
-
Decreased Ih in hippocampal area CA1 pyramidal neurons after perinatal seizure-inducing hypoxia
-
Zhang K, Peng BW, Sanchez RM. 2006. Decreased Ih in hippocampal area CA1 pyramidal neurons after perinatal seizure-inducing hypoxia. Epilepsia 47: 1023–1028.
-
(2006)
Epilepsia
, vol.47
, pp. 1023-1028
-
-
Zhang, K.1
Peng, B.W.2
Sanchez, R.M.3
-
88
-
-
67249099449
-
Association with the auxiliary subunit PEX5R/ Trip8b controls responsiveness of HCN channels to cAMP and adrenergic stimulation
-
Zolles G, Wenzel D, Bildl W, Schulte U, Hofmann A, Muller CS, Thumfart JO, Vlachos A, Deller T, Pfeifer A, et al. 2009. Association with the auxiliary subunit PEX5R/ Trip8b controls responsiveness of HCN channels to cAMP and adrenergic stimulation. Neuron 62: 814–825.
-
(2009)
Neuron
, vol.62
, pp. 814-825
-
-
Zolles, G.1
Wenzel, D.2
Bildl, W.3
Schulte, U.4
Hofmann, A.5
Muller, C.S.6
Thumfart, J.O.7
Vlachos, A.8
Deller, T.9
Pfeifer, A.10
|