Evolutionary emergence of N-glycosylation as a variable promoter of HCN channel surface expression

American Journal of Physiology - Cell Physiology

Volumn 298, Issue 5, 2010, Pages

  Hegle, Andrew P ^a   Nazzari, Hamed ^a   Roth, Andrew ^a   Angoli, Damiano ^a   Accili, Eric A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Embryonic heart; Hyperpolarization activated cyclic nucleotide modulated channel mediated current; Ion channels; Molecular evolution; N linked glycosylation

Indexed keywords

CYCLIC NUCLEOTIDE GATED CHANNEL; PROTEIN HCN1; PROTEIN HCN2; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; GENE DUPLICATION; GENE EXPRESSION; GLYCOSYLATION; HEART; HYPERPOLARIZATION; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; EMBRYO, MAMMALIAN; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; GLYCOSYLATION; HEART; ION CHANNELS; MICE; MOLECULAR SEQUENCE DATA; MYOCARDIUM; PHYLOGENY; POTASSIUM CHANNELS; RATS;

MAMMALIA;

EID: 77951495576     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00389.2009     Document Type: Article

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