Muscle sphingolipids during rest and exercise: a C18:0 signature for insulin resistance in humans

Diabetologia

Volumn 59, Issue 4, 2016, Pages 785-798

  Bergman, Bryan C ^a   Brozinick, Joseph T ^b   Strauss, Allison ^a   Bacon, Samantha ^a   Kerege, Anna ^a   Bui, Hai Hoang ^b   Sanders, Phil ^b   Siddall, Parker ^b   Wei, Tao ^b   Thomas, Melissa K ^b   Kuo, Ming Shang ^b   Perreault, Leigh ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Athlete s paradox; Insulin sensitivity; Lipid composition

Indexed keywords

ARACHIDIC ACID; ARACHIDONIC ACID; BEHENIC ACID; CERAMIDE; DIHYDROCERAMIDE; DOCOSAHEXAENOIC ACID; ERUCIC ACID; FATTY ACID; GANGLIOSIDE GM3; GLUCOSYLCERAMIDE; I KAPPA B KINASE ALPHA; ICOSAPENTAENOIC ACID; LIGNOCERIC ACID; LINOLEIC ACID; LINOLENIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUSCLE PROTEIN; MYRISTIC ACID; OLEIC ACID; PALMITIC ACID; PALMITOLEIC ACID; PROTEIN KINASE B; SPHINGOLIPID; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; STEARIC ACID; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; ENDURANCE TRAINING; EXERCISE; FEMALE; GENETIC TRANSCRIPTION; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPOGENESIS; MAJOR CLINICAL STUDY; MALE; MYOSITIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; REST; SKELETAL MUSCLE; TRAINING; CLINICAL TRIAL; METABOLISM; PHYSIOLOGY; WESTERN BLOTTING;

ADULT; BLOTTING, WESTERN; CERAMIDES; EXERCISE; HUMANS; INSULIN RESISTANCE; MUSCLE, SKELETAL; REST; SPHINGOLIPIDS;

EID: 84959557399     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3850-y     Document Type: Article

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