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Volumn 30, Issue 3, 2016, Pages 426-438

Ramalin-Mediated Apoptosis Is Enhanced by Autophagy Inhibition in Human Breast Cancer Cells

Author keywords

apoptosis; autophagy; breast cancer cells; ramalin

Indexed keywords

3 METHYLADENINE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; PROTEIN BCL 2; PROTEIN P62; RAMALIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 3-METHYLADENINE; ADENINE; ANTIOXIDANT; APOPTOSIS INDUCING FACTOR; ATG5 PROTEIN, HUMAN; AUTOPHAGY RELATED PROTEIN 5; BAX PROTEIN, HUMAN; BCL2 PROTEIN, HUMAN; BIOLOGICAL PRODUCT; CASPASE; GLUTAMIC ACID DERIVATIVE; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN BAX;

EID: 84959544923     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5544     Document Type: Article
Times cited : (12)

References (45)
  • 1
    • 58349104775 scopus 로고    scopus 로고
    • Oestrogen-receptor-positive breast cancer: Towards bridging histopathological and molecular classifications
    • Badve S, Nakshatri H,. 2009. Oestrogen-receptor-positive breast cancer: towards bridging histopathological and molecular classifications. J Clin Pathol 62: 6-12.
    • (2009) J Clin Pathol , vol.62 , pp. 6-12
    • Badve, S.1    Nakshatri, H.2
  • 2
    • 0242522206 scopus 로고    scopus 로고
    • Regulation of apoptosis by Bcl-2 family proteins
    • Burlacu A,. 2003. Regulation of apoptosis by Bcl-2 family proteins. J Cell Mol Med 7: 249-257.
    • (2003) J Cell Mol Med , vol.7 , pp. 249-257
    • Burlacu, A.1
  • 3
    • 41149152733 scopus 로고    scopus 로고
    • How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
    • Chipuk JE, Green DR,. 2008. How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol 18: 157-164.
    • (2008) Trends Cell Biol , vol.18 , pp. 157-164
    • Chipuk, J.E.1    Green, D.R.2
  • 4
    • 77957319672 scopus 로고    scopus 로고
    • Quercetin-mediated cell cycle arrest and apoptosis involving activation of a caspase cascade through the mitochondrial pathway in human breast cancer MCF-7 cells
    • Chou C, Yang J, Lu H, et al., 2010. Quercetin-mediated cell cycle arrest and apoptosis involving activation of a caspase cascade through the mitochondrial pathway in human breast cancer MCF-7 cells. Arch Pharm Res 33: 1181-1191.
    • (2010) Arch Pharm Res , vol.33 , pp. 1181-1191
    • Chou, C.1    Yang, J.2    Lu, H.3
  • 5
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C, Fang M, Li Y, Li L, Wang X,. 2000. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102: 33-42.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 6
    • 33745102306 scopus 로고    scopus 로고
    • Estrogen receptors: Role in breast cancer
    • Duffy MJ,. 2006. Estrogen receptors: role in breast cancer. Crit Rev Clin Lab Sci 43: 325-347.
    • (2006) Crit Rev Clin Lab Sci , vol.43 , pp. 325-347
    • Duffy, M.J.1
  • 7
    • 67549142261 scopus 로고    scopus 로고
    • Life and death partners: Apoptosis, autophagy and the cross-talk between them
    • Eisenberg-Lerner A, Bialik S, Simon H, Kimchi A,. 2009. Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ 16: 966-975.
    • (2009) Cell Death Differ , vol.16 , pp. 966-975
    • Eisenberg-Lerner, A.1    Bialik, S.2    Simon, H.3    Kimchi, A.4
  • 8
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A review of programmed cell death
    • Elmore S,. 2007. Apoptosis: a review of programmed cell death. Toxicol Pathol 35: 495-516.
    • (2007) Toxicol Pathol , vol.35 , pp. 495-516
    • Elmore, S.1
  • 9
    • 0033593230 scopus 로고    scopus 로고
    • Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
    • Finucane DM, Bossy-Wetzel E, Waterhouse NJ, Cotter TG, Green DR,. 1999. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem 274: 2225-2233.
    • (1999) J Biol Chem , vol.274 , pp. 2225-2233
    • Finucane, D.M.1    Bossy-Wetzel, E.2    Waterhouse, N.J.3    Cotter, T.G.4    Green, D.R.5
  • 10
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumour suppressor mechanism
    • Gozuacik D, Kimchi A,. 2004. Autophagy as a cell death and tumour suppressor mechanism. Oncogene 23: 2891-2906.
    • (2004) Oncogene , vol.23 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 11
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA,. 2000. The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 13
    • 33745961862 scopus 로고    scopus 로고
    • The p53-Bcl-2 connection
    • Hemann M, Lowe S,. 2006. The p53-Bcl-2 connection. Cell Death Differ 13: 1256-1259.
    • (2006) Cell Death Differ , vol.13 , pp. 1256-1259
    • Hemann, M.1    Lowe, S.2
  • 14
    • 84867731370 scopus 로고    scopus 로고
    • zVAD-fmk prevents cisplatin-induced cleavage of autophagy proteins but impairs autophagic flux and worsens renal function
    • Herzog C, Yang C, Holmes A, Kaushal GP,. 2012. zVAD-fmk prevents cisplatin-induced cleavage of autophagy proteins but impairs autophagic flux and worsens renal function. Am J Physiol Renal Physiol 303: F1239-F1250.
    • (2012) Am J Physiol Renal Physiol , vol.303 , pp. F1239-F1250
    • Herzog, C.1    Yang, C.2    Holmes, A.3    Kaushal, G.P.4
  • 15
    • 0035961202 scopus 로고    scopus 로고
    • Breast cancer: Hormones and other risk factors
    • Hulka BS, Moorman PG,. 2001. Breast cancer: hormones and other risk factors. Maturitas 38: 103-113.
    • (2001) Maturitas , vol.38 , pp. 103-113
    • Hulka, B.S.1    Moorman, P.G.2
  • 16
    • 0033407502 scopus 로고    scopus 로고
    • The significance of lichens and their metabolites
    • Huneck S,. 1999. The significance of lichens and their metabolites. Naturwissenschaften 86: 559-570.
    • (1999) Naturwissenschaften , vol.86 , pp. 559-570
    • Huneck, S.1
  • 17
    • 84893677749 scopus 로고    scopus 로고
    • Autophagy in breast cancer and its implications for therapy
    • Jain K, Paranandi KS, Sridharan S, Basu A,. 2013. Autophagy in breast cancer and its implications for therapy. Am J Cancer Res 3: 251-256.
    • (2013) Am J Cancer Res , vol.3 , pp. 251-256
    • Jain, K.1    Paranandi, K.S.2    Sridharan, S.3    Basu, A.4
  • 18
    • 34748884951 scopus 로고    scopus 로고
    • Caspase-7 mediated cleavage of proteasome subunits during apoptosis
    • Jang M, Park BC, Lee AY, et al., 2007. Caspase-7 mediated cleavage of proteasome subunits during apoptosis. Biochem Biophys Res Commun 363: 388-394.
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 388-394
    • Jang, M.1    Park, B.C.2    Lee, A.Y.3
  • 19
    • 0032546795 scopus 로고    scopus 로고
    • Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
    • Janicke RU, Ng P, Sprengart ML, Porter AG,. 1998. Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. J Biol Chem 273: 15540-15545.
    • (1998) J Biol Chem , vol.273 , pp. 15540-15545
    • Janicke, R.U.1    Ng, P.2    Sprengart, M.L.3    Porter, A.G.4
  • 21
    • 0037501319 scopus 로고    scopus 로고
    • The oestrogen receptor: A model for molecular medicine
    • Jensen EV, Jordan VC,. 2003. The oestrogen receptor: a model for molecular medicine. Clin Cancer Res 9: 1980-1989.
    • (2003) Clin Cancer Res , vol.9 , pp. 1980-1989
    • Jensen, E.V.1    Jordan, V.C.2
  • 22
    • 33846244269 scopus 로고    scopus 로고
    • Role of autophagy in cancer: Management of metabolic stress
    • Jin S, White E,. 2007. Role of autophagy in cancer: management of metabolic stress. Autophagy 3: 28-31.
    • (2007) Autophagy , vol.3 , pp. 28-31
    • Jin, S.1    White, E.2
  • 23
    • 77950821063 scopus 로고    scopus 로고
    • Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway
    • Jin S, Zhang QY, Kang XM, Wang JX, Zhao WH,. 2010. Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway. Ann Oncol 21: 263-268.
    • (2010) Ann Oncol , vol.21 , pp. 263-268
    • Jin, S.1    Zhang, Q.Y.2    Kang, X.M.3    Wang, J.X.4    Zhao, W.H.5
  • 24
    • 37649007431 scopus 로고    scopus 로고
    • Selective estrogen-receptor modulators and antihormonal resistance in breast cancer
    • Jordan VC, O'Malley BW,. 2007. Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. J Clin Oncol 25: 5815-5824.
    • (2007) J Clin Oncol , vol.25 , pp. 5815-5824
    • Jordan, V.C.1    O'Malley, B.W.2
  • 25
    • 77958609008 scopus 로고    scopus 로고
    • Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells
    • Kanematsu S, Uehara N, Miki H, et al., 2010. Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells. Anticancer Res 30: 3381-3390.
    • (2010) Anticancer Res , vol.30 , pp. 3381-3390
    • Kanematsu, S.1    Uehara, N.2    Miki, H.3
  • 26
    • 84870622028 scopus 로고    scopus 로고
    • Autophagy protects proximal tubular cells from injury and apoptosis
    • Kaushal GP,. 2012. Autophagy protects proximal tubular cells from injury and apoptosis. Kidney Int 82: 1250-1253.
    • (2012) Kidney Int , vol.82 , pp. 1250-1253
    • Kaushal, G.P.1
  • 28
    • 84878366679 scopus 로고    scopus 로고
    • Streptococcus pneumoniae ClpP protease induces apoptosis via caspase-independent pathway in human neuroblastoma cells: Cytoplasmic relocalization of p53
    • Lee J, Kim J, Rhee D, Pyo S,. 2013. Streptococcus pneumoniae ClpP protease induces apoptosis via caspase-independent pathway in human neuroblastoma cells: cytoplasmic relocalization of p53. Toxicon 70: 142-152.
    • (2013) Toxicon , vol.70 , pp. 142-152
    • Lee, J.1    Kim, J.2    Rhee, D.3    Pyo, S.4
  • 29
    • 0037663541 scopus 로고    scopus 로고
    • Estrogen receptor-α regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells
    • Morelli C, Garofalo C, Bartucci M, Surmacz E,. 2003. Estrogen receptor-α regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells. Oncogene 22: 4007-4016.
    • (2003) Oncogene , vol.22 , pp. 4007-4016
    • Morelli, C.1    Garofalo, C.2    Bartucci, M.3    Surmacz, E.4
  • 30
    • 0034911403 scopus 로고    scopus 로고
    • Pharmaceutically relevant metabolites from lichens
    • Müller K,. 2001. Pharmaceutically relevant metabolites from lichens. Appl Microbiol Biotechnol 56: 9-16.
    • (2001) Appl Microbiol Biotechnol , vol.56 , pp. 9-16
    • Müller, K.1
  • 31
    • 84922459674 scopus 로고    scopus 로고
    • Korean Red Ginseng inhibits apoptosis in neuroblastoma cells via estrogen receptor beta-mediated phosphatidylinositol-3 kinase/Akt signaling
    • Nguyen CT, Luong TT, Kim GL, Pyo S, Rhee DK,. 2015. Korean Red Ginseng inhibits apoptosis in neuroblastoma cells via estrogen receptor beta-mediated phosphatidylinositol-3 kinase/Akt signaling. J Ginseng Res 39: 69-75.
    • (2015) J Ginseng Res , vol.39 , pp. 69-75
    • Nguyen, C.T.1    Luong, T.T.2    Kim, G.L.3    Pyo, S.4    Rhee, D.K.5
  • 32
    • 0034641932 scopus 로고    scopus 로고
    • From bench to clinic with apoptosis-based therapeutic agents
    • Nicholson DW,. 2000. From bench to clinic with apoptosis-based therapeutic agents. Nature 407: 810-816.
    • (2000) Nature , vol.407 , pp. 810-816
    • Nicholson, D.W.1
  • 33
    • 80255132931 scopus 로고    scopus 로고
    • Ramalin, a novel nontoxic antioxidant compound from the Antarctic lichen Ramalina terebrata
    • Paudel B, Bhattarai HD, Koh HY, et al., 2011. Ramalin, a novel nontoxic antioxidant compound from the Antarctic lichen Ramalina terebrata. Phytomedicine 18: 1285-1290.
    • (2011) Phytomedicine , vol.18 , pp. 1285-1290
    • Paudel, B.1    Bhattarai, H.D.2    Koh, H.Y.3
  • 34
    • 76249124608 scopus 로고    scopus 로고
    • Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
    • Puissant A, Robert G, Fenouille N, et al., 2010. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. Cancer Res 70: 1042-1052.
    • (2010) Cancer Res , vol.70 , pp. 1042-1052
    • Puissant, A.1    Robert, G.2    Fenouille, N.3
  • 35
    • 84868567192 scopus 로고    scopus 로고
    • When autophagy meets cancer through p62/SQSTM1
    • Puissant A, Fenouille N, Auberger P,. 2012. When autophagy meets cancer through p62/SQSTM1. Cancer Res 2: 397-413.
    • (2012) Cancer Res , vol.2 , pp. 397-413
    • Puissant, A.1    Fenouille, N.2    Auberger, P.3
  • 36
    • 70849113936 scopus 로고    scopus 로고
    • Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death
    • Robert G, Sahra IB, Puissant A, et al., 2009. Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death. PLoS One 4 e7889.
    • (2009) PLoS One , vol.4
    • Robert, G.1    Sahra, I.B.2    Puissant, A.3
  • 37
    • 23844549918 scopus 로고    scopus 로고
    • Breast cancer molecular subtypes respond differently to preoperative chemotherapy
    • Rouzier R, Perou CM, Symmans WF, et al., 2005. Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin Cancer Res 11: 5678-5685.
    • (2005) Clin Cancer Res , vol.11 , pp. 5678-5685
    • Rouzier, R.1    Perou, C.M.2    Symmans, W.F.3
  • 38
    • 38449111028 scopus 로고    scopus 로고
    • p53, BRCA1 and breast cancer chemoresistance
    • Scata KA, El-Deiry WS,. 2007. p53, BRCA1 and breast cancer chemoresistance. Adv Exp Med Biol 608: 70-86.
    • (2007) Adv Exp Med Biol , vol.608 , pp. 70-86
    • Scata, K.A.1    El-Deiry, W.S.2
  • 39
    • 84864004791 scopus 로고    scopus 로고
    • Distinct genes related to drug response identified in ER positive and ER negative breast cancer cell lines
    • Shen K, Rice SD, Gingrich DA, et al., 2012. Distinct genes related to drug response identified in ER positive and ER negative breast cancer cell lines. PLoS One 7 e40900:.
    • (2012) PLoS One , vol.7
    • Shen, K.1    Rice, S.D.2    Gingrich, D.A.3
  • 40
    • 38449084047 scopus 로고    scopus 로고
    • Isoprenoid-independent pathway is involved in apoptosis induced by risedronate, a bisphosphonate, in which Bim plays a critical role in breast cancer cell line MCF-7
    • Suyama K, Noguchi Y, Tanaka T, et al., 2007. Isoprenoid-independent pathway is involved in apoptosis induced by risedronate, a bisphosphonate, in which Bim plays a critical role in breast cancer cell line MCF-7. Oncol Rep 18: 1291-1298.
    • (2007) Oncol Rep , vol.18 , pp. 1291-1298
    • Suyama, K.1    Noguchi, Y.2    Tanaka, T.3
  • 41
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: Outer membrane permeabilization and beyond
    • Tait SW, Green DR,. 2010. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 11: 621-632.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 42
    • 50549090954 scopus 로고    scopus 로고
    • Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner
    • Tsao CH, Su HL, Lin YL, et al., 2008. Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner. J Gen Virol 89: 1930-1941.
    • (2008) J Gen Virol , vol.89 , pp. 1930-1941
    • Tsao, C.H.1    Su, H.L.2    Lin, Y.L.3
  • 43
    • 77955423341 scopus 로고    scopus 로고
    • Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation
    • Wong CH, Iskandar KB, Yadav SK, Hirpara JL, Loh T, Pervaiz S,. 2010. Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation. PLoS One 5 e9996:.
    • (2010) PLoS One , vol.5
    • Wong, C.H.1    Iskandar, K.B.2    Yadav, S.K.3    Hirpara, J.L.4    Loh, T.5    Pervaiz, S.6
  • 44
    • 84862974996 scopus 로고    scopus 로고
    • Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy
    • Yang PM, Tseng HH, Peng CW, Chen WS, Chiu SJ,. 2012. Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy. Int J Oncol 40: 469-478.
    • (2012) Int J Oncol , vol.40 , pp. 469-478
    • Yang, P.M.1    Tseng, H.H.2    Peng, C.W.3    Chen, W.S.4    Chiu, S.J.5
  • 45
    • 0347626252 scopus 로고    scopus 로고
    • Autophagy: A regulated bulk degradation process inside cells
    • Yoshimori T,. 2004. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun 313: 453-458.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 453-458
    • Yoshimori, T.1


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