Metformin-associated lactic acidosis: Current perspectives on causes and risk

Metabolism: Clinical and Experimental

Volumn 65, Issue 2, 2016, Pages 20-29

  Defronzo, Ralph ^a   Fleming, G Alexander ^b   Chen, Kim ^c   Bicsak, Thomas A ^c  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Kinexum LLC   (United States)

^c Elcelyx Therapeutics Inc   (United States)

Author keywords

Drug mechanism; Lactic acidosis; MALA; Metformin; Renal impairment

Indexed keywords

BIGUANIDE DERIVATIVE; LACTIC ACID; METFORMIN; ANTIDIABETIC AGENT;

DRUG BLOOD LEVEL; DRUG CONTRAINDICATION; DRUG INDUCED DISEASE; DRUG METABOLISM; DRUG OVERDOSE; HUMAN; KIDNEY FAILURE; KIDNEY FUNCTION; LACTATE BLOOD LEVEL; LACTIC ACIDOSIS; METFORMIN ASSOCIATED LACTIC ACIDOSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; REVIEW; RISK FACTOR; CHEMICALLY INDUCED; DIABETES MELLITUS, TYPE 2; METABOLISM;

ACIDOSIS, LACTIC; DIABETES MELLITUS, TYPE 2; HUMANS; HYPOGLYCEMIC AGENTS; METFORMIN; RISK FACTORS;

EID: 84959528193     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2015.10.014     Document Type: Review

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