Designing biomaterials to direct biological responses

Annals of the New York Academy of Sciences

Volumn 875, Issue , 1999, Pages 24-35

  Healy, Kevin E ^a,b,c   Rezania, Alireza ^a,b   Stile, Ranee A ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Northwestern University   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; COLLAGEN; HEPARIN BINDING PROTEIN; PEPTIDE; POLYMER; PROTEIN; VITRONECTIN RECEPTOR;

ARTIFICIAL ORGAN; BIOCOMPATIBILITY; BIOENGINEERING; BONE; CELL MOTILITY; CONFERENCE PAPER; EXTRACELLULAR MATRIX; GENE EXPRESSION; HYDROGEL; MINERALIZATION; OSTEOBLAST; PHENOTYPE; TISSUE REGENERATION;

EID: 0032773487     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb08491.x     Document Type: Conference Paper

References (31)

1. 1. CRUBEZY, E., P. MURAIL, L. GIRARD & J.-P. BERNADOU. 1998. False teeth of the Roman world. Nature 391: 29.
2. 2. HOFFMAN, A. S. 1992. Molecular bioengineering of biomaterials in the 1990s and beyond: a growing liaison of polymers with molecular biology. Artificial Organs 16: 43-49.
3. 3. DRUMHELLER, P.D., D.L. ELBERT & J.A. HUBBELL. 1994. Multifunctional poly(ethylene glycol) semi-interpenetrating networks as highly selective adhesive substrates for bioadhesive peptide grafting. Biotechnol. Bioeng. 43: 772-780.
4. 4. MASSIA, S.P. & J.A. HUBBELL. 1991. An RGD spacing of 440 nm is sufficient for integrin (α5β3-mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation. J. Cell. Biol. 114: 1089-1100.
5. 1. J. Biol. Chem. 267: 14019-14026.
6. 6. REZANIA, A., C.H. THOMAS, A.B. BRANGER, C.M. WATERS & K.E. HEALY. 1997. The detachment strength and morphology of bone cells contacting materials modified with a peptide sequence found within bone sialoprotein. J. Biomed. Mater. Res. 37: 9-19.
7. 7. BEARINGER, J.P., D.G. CASTNER & K.E. HEALY. 1998. Biomolecular modification of p(AAm-co-EG/AA) IPNs supports osteoblast adhesion and phenotypic expression. J. Biomater. Sci. Polymer Edn. 9: 629-652.
8. 8. BIANCO, P., L.W. FISHER, M.F. YOUNG, J.D. TERMINE & P.G. ROBEY. 1991. Expression of bone sialoprotein (BSP) in developing human tissue. Calcif. Tissue. Int. 49: 421-426.
9. 9. MINTZ, K.P., W.J. GRZESIK, R.J. MIDURA, P.G. ROBEY, J.D. TERMINE & L.W. FISHER. 1993. Purification and fragmentation of nondenatured bone sialoprotein: evidence for a cryptic, RGD-resistant cell attachment domain. J. Bone. Min. Res. 8: 985-995.
10. 10. SOMERMAN, M.J., L.W. FISHER, R.A. FOSTER, J.J. SAUK. 1988. Human bone sialoprotein I and II enhance fibroblast attachment in vitro. Calcif. Tissue. Int. 43: 50-53.
11. 11. WANG, J., J.G. KENNEDY, J.R. KASSER, M.J. GLIMCHER & E. SALIH. 1998. Novel bioactive property of purified native bone sialoprotein in bone repair of a calvarial defect. Transactions of the 44th annual Orthopaedic Research Society Meeting 23-2: 1007.
12. 12. DALTON, B.A., C.D. MCFARLAND, P.A. UNDERWOOD & J.G. STEELE. 1995. Role of the heparin binding domain of fibronectin in attachment and spreading of human bone-derived cells. J.Cell. Sci. 108: 2083-2092.
13. 13. WOODS, A., J.R. COUCHMAN, S. JOHANSSON & M. HOOK. 1986. Adhesion and cytoskeletal Organisation of fibroblasts in response to fibronectin fragments. EMBO. J. 5: 665-670.
14. 14. PULEO, D.A. & R. BIZIOS. 1991. RGDS tetrapeptide binds to osteoblasts and inhibits fibronectin-mediated adhesion. Bone 12: 271-276.
15. 15. LATERRA, J., J.E. SILBERT & L.A. CULP. 1983. Cell surface heparan sulfate mediates some adhesive responses to glycosaminoglycan-binding matrices, including fibronectin. J. Cell. Biol 96: 112-123.
16. 16. REZANIA, A., R. JOHNSON, A.R. LEFKOW & K.E. HEALY. 1999. Bioactivation of metal oxide surfaces: I. Surface characterization and cell response. Langmuir. Submitted.
17. 17. REZANIA, A. & K.E. HEALY. 1999. Biomimetic peptide surfaces that regulate adhesion, spreading, cytoskeletal organization, and mineralization of matrix deposited by osteoblast-like cells. Biotech. Progress. 15: 19-32.
18. 18. REZANIA, A. & K.E. HEALY. 1999. Integrin subunits responsible for adhesion of human osteoblast-like cells to RGD containing surfaces. J. Orthop. Res. In press.
19. 19. WHITSON, S.W., M.A. EHITSON, D.E. BOWERS & M.C. FALK. 1992. Factors influencing synthesis and mineralization of bone matrix from fetal bovine cells grown in vitro. J. Bone. Min. Res. 7: 727-741.
20. 20. HEALY, K.E., C.H. THOMAS, A. REZANIA, J.E. KIM, P.J. MCKEOWN, B. LOM & P.E. HOCKBERGER. 1996. Kinetics of bone cell organization and mineralization on materials with patterned surface chemistry. Biomaterials 16: 195-208.
21. 21. THOMAS, C.H., C.D. MCFARLAND, M.L. JENKINS, A. REZANIA, J.G. STEELE & K.E. HEALY. 1997. The role of vitronectin in the attachment and spatial distribution of bone-derived cells on materials with patterned surface chemistry. J. Biomed. Mater. Res. 37: 81-90.
22. 22. BEARINGER, J.P., D.G. CASTNER, S.L. GOLLEDGE, A. REZANIA, S. HUBCHAK & K.E. HEALY. 1997. P(AAm-co-EG) interpenetrating polymer networks grafted to oxide surfaces: Surface characetrization, protein adsorption, and cell detachment studies. Langmuir 13: 5175-5183.
23. 23. REZANIA, A., C. H. THOMAS & K. E. HEALY. 1997. A probabilistic approach to measure the strength of bone cell adhesion to chemically modified surfaces. Ann. Biomed. Eng. 25: 190-203.
24. 24. Langer, R., J.P. Vacanti. 1993. Tissue engineering. Science 260: 920-926.
25. 25. STILE, R.A., W.R. BURGHARDT & K.E. HEALY. 1999. Synthesis and characterization of injectable Poly(N-isopropylacrylamide)-based hydrogels that support tissue formation in vitro. Macromolecules. In press.
26. 26. HESKINS, M. & J.E. GUILLET. 1968. Solution properties of poly(N-isopropylacrylamide). J. Macromol. Sci. Chem. Edition A2: 1441-1455.
27. 27. CHEN, G. & A.S. HOFFMAN. 1995. Graft copolymers that exhibit temperature-induced phase transitions over a wide range of pH. Nature 373: 49-52.
28. 28. HOFFMAN, A.S. 1991. Environmentally sensitive polymers and hydrogels: "Smart" biomaterials. MRS Bulletin 16: 42-46.
29. 29. HIROKAWA, Y. & T. TANAKA. 1984. Volume phase transition in a nonionic gel. J. Chem. Phys. 81: 6379-6380.
30. 30. HOFFMAN, A.S., A. AFRASSIABI & L.C. DONG. 1986. Thermally reversible hydrogels: II. Delivery and selective removal of substances from aqueous solutions. J. Controlled Release 4: 213-222.
31. 31. WHANG, K., K.E. HEALY, D.R. ELENZ, et al. 1999. Engineering bone regeneration with bioabsorbable scaffolds with novel microarchitecture. Tissue Eng. 5: 35-51.