-
1
-
-
1642416884
-
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and Vitamin D metabolism
-
Shimada T, Kakitani M, Yamazaki Y, et al., Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest. 2004; 113 (4): 561-8.
-
(2004)
J Clin Invest
, vol.113
, Issue.4
, pp. 561-568
-
-
Shimada, T.1
Kakitani, M.2
Yamazaki, Y.3
-
2
-
-
80054930335
-
PTH ablation ameliorates the anomalies of Fgf23-deficient mice by suppressing the elevated Vitamin D and calcium levels
-
Yuan Q, Sitara D, Sato T, et al., PTH ablation ameliorates the anomalies of Fgf23-deficient mice by suppressing the elevated vitamin D and calcium levels. Endocrinology. 2011; 152 (11): 4053-61.
-
(2011)
Endocrinology
, vol.152
, Issue.11
, pp. 4053-4061
-
-
Yuan, Q.1
Sitara, D.2
Sato, T.3
-
3
-
-
84879841514
-
Fibroblast growth factor 23 enhances renal klotho abundance
-
Takenaka T, Watanabe Y, Inoue T, Miyazaki T, Suzuki H., Fibroblast growth factor 23 enhances renal klotho abundance. Pflugers Arch. 2013; 465: 935-43.
-
(2013)
Pflugers Arch
, vol.465
, pp. 935-943
-
-
Takenaka, T.1
Watanabe, Y.2
Inoue, T.3
Miyazaki, T.4
Suzuki, H.5
-
4
-
-
77955272026
-
Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects
-
Yamazaki Y, Imura A, Urakawa I, et al., Establishment of sandwich ELISA for soluble alpha-Klotho measurement: age-dependent change of soluble alpha-Klotho levels in healthy subjects. Biochem Biophys Res Commun. 2010; 398 (3): 513-8.
-
(2010)
Biochem Biophys Res Commun
, vol.398
, Issue.3
, pp. 513-518
-
-
Yamazaki, Y.1
Imura, A.2
Urakawa, I.3
-
5
-
-
84871924970
-
The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice
-
Chen TH, Kuro-o M, Chen CH, et al., The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice. Eur J Pharmacol. 2013; 698: 67-73.
-
(2013)
Eur J Pharmacol
, vol.698
, pp. 67-73
-
-
Chen, T.H.1
Kuro-O, M.2
Chen, C.H.3
-
6
-
-
84954453627
-
Renal production, uptake, and handling of circulating αklotho
-
Epub 2015 May 14. pii: ASN. 2014101030
-
Hu MC, Shi M, Zhang J, et al., Renal production, uptake, and handling of circulating αKlotho. J Am Soc Nephrol. Epub 2015 May 14. pii: ASN. 2014101030.
-
J Am Soc Nephrol
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
-
7
-
-
0019485450
-
Localization of 25-hydroxyvitamin D3 1 alpha-hydroxylase and 24-hydroxylase along the rat nephron
-
Kawashima H, Torikai S, Kurokawa K., Localization of 25-hydroxyvitamin D3 1 alpha-hydroxylase and 24-hydroxylase along the rat nephron. Proc Natl Acad Sci USA. 1981; 78 (2): 1199-203.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, Issue.2
, pp. 1199-1203
-
-
Kawashima, H.1
Torikai, S.2
Kurokawa, K.3
-
8
-
-
84899770392
-
Calcitriol supplementation improves endothelium-dependent vasodilation in rat hypertensive renal injury
-
Takenaka T, Inoue T, Ohno Y, et al., Calcitriol supplementation improves endothelium-dependent vasodilation in rat hypertensive renal injury. Kidney Blood Press Res. 2014; 39: 17-27.
-
(2014)
Kidney Blood Press Res
, vol.39
, pp. 17-27
-
-
Takenaka, T.1
Inoue, T.2
Ohno, Y.3
-
9
-
-
79953138206
-
Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice
-
Doi S, Zou Y, Togao O, et al., Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice. J Biol Chem. 2011; 286: 8655-65.
-
(2011)
J Biol Chem
, vol.286
, pp. 8655-8665
-
-
Doi, S.1
Zou, Y.2
Togao, O.3
-
10
-
-
24944481544
-
Suppression of aging in mice by the hormone Klotho
-
Kurosu H, Yamamoto M, Clark JD, et al., Suppression of aging in mice by the hormone Klotho. Science. 2005; 309 (5742): 1829-33.
-
(2005)
Science
, vol.309
, Issue.5742
, pp. 1829-1833
-
-
Kurosu, H.1
Yamamoto, M.2
Clark, J.D.3
-
11
-
-
78650600602
-
Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity
-
Kusaba T, Okigaki M, Matui A, et al., Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity. Proc Natl Acad Sci USA. 2010; 107 (45): 19308-13.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.45
, pp. 19308-19313
-
-
Kusaba, T.1
Okigaki, M.2
Matui, A.3
-
12
-
-
34547908461
-
Augmented Wnt signaling in a mammalian model of accelerated aging
-
Liu H, Fergusson MM, Castilho RM, et al., Augmented Wnt signaling in a mammalian model of accelerated aging. Science. 2007; 317 (5839): 803-6.
-
(2007)
Science
, vol.317
, Issue.5839
, pp. 803-806
-
-
Liu, H.1
Fergusson, M.M.2
Castilho, R.M.3
-
13
-
-
33845631059
-
Klotho converts canonical FGF receptor into a specific receptor for F GF23
-
Urakawa I, Yamazaki Y, Shimada T, et al., Klotho converts canonical FGF receptor into a specific receptor for F GF23. Nature. 2006; 444 (7120): 770-4.
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 770-774
-
-
Urakawa, I.1
Yamazaki, Y.2
Shimada, T.3
-
14
-
-
84938571665
-
Anti-albuminuric actions of calcilytics in the remnant kidney
-
Epub 2015 May 27. doi: 10.1152/ajprenal.00003.2015
-
Takenaka T, Inoue T, Miyazaki T, et al., Anti-albuminuric actions of calcilytics in the remnant kidney. Am J Physiol Renal Physiol. Epub 2015 May 27. doi: 10.1152/ajprenal.00003.2015
-
Am J Physiol Renal Physiol
-
-
Takenaka, T.1
Inoue, T.2
Miyazaki, T.3
-
15
-
-
27144440831
-
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
-
Chang Q, Hoefs S, van der Kemp AW, Topala CN, Bindels RJ, Hoenderop JG., The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science. 2005; 310 (5747): 490-3.
-
(2005)
Science
, vol.310
, Issue.5747
, pp. 490-493
-
-
Chang, Q.1
Hoefs, S.2
Van Der Kemp, A.W.3
Topala, C.N.4
Bindels, R.J.5
Hoenderop, J.G.6
-
16
-
-
77956642900
-
Klotho: A novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule
-
Hu MC, Shi M, Zhang J, et al., Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J. 2010; 24 (9): 3438-50.
-
(2010)
FASEB J
, vol.24
, Issue.9
, pp. 3438-3450
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
-
17
-
-
38749126432
-
Expression and role of connexins in the rat renal vasculature
-
Takenaka T, Inoue T, Kanno Y, et al., Expression and role of connexins in the rat renal vasculature. Kidney Int. 2008; 73 (4): 415-22.
-
(2008)
Kidney Int
, vol.73
, Issue.4
, pp. 415-422
-
-
Takenaka, T.1
Inoue, T.2
Kanno, Y.3
-
18
-
-
4644245343
-
Acute hypotension induced by aortic clamp vs. PTH provokes distinct proximal tubule Na+ transporter redistribution patterns
-
Leong PK, Yang LE, Lin HW, Holstein-Rathlou NH, McDonough AA., Acute hypotension induced by aortic clamp vs. PTH provokes distinct proximal tubule Na+ transporter redistribution patterns. Am J Physiol. 2004; 287: R878-85.
-
(2004)
Am J Physiol
, vol.287
, pp. R878-R885
-
-
Leong, P.K.1
Yang, L.E.2
Lin, H.W.3
Holstein-Rathlou, N.H.4
McDonough, A.A.5
-
19
-
-
84867029524
-
Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism
-
Olauson H, Lindberg K, Amin R, et al., Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism. J Am Soc Nephrol. 2012; 23 (10): 1641-51.
-
(2012)
J Am Soc Nephrol
, vol.23
, Issue.10
, pp. 1641-1651
-
-
Olauson, H.1
Lindberg, K.2
Amin, R.3
-
20
-
-
0033775213
-
Proximal tubular phosphate reabsorption: Molecular mechanisms
-
Murer H, Hernando N, Forster I, Biber J., Proximal tubular phosphate reabsorption: Molecular mechanisms. Physiol Rev. 2000; 80 (4): 1373-409.
-
(2000)
Physiol Rev
, vol.80
, Issue.4
, pp. 1373-1409
-
-
Murer, H.1
Hernando, N.2
Forster, I.3
Biber, J.4
-
21
-
-
0036150620
-
Renal interstitial fluid concentrations of angiotensins i and II in anesthetized rats
-
Nishiyama A, Seth DM, Navar LG., Renal interstitial fluid concentrations of angiotensins I and II in anesthetized rats. Hypertension. 2002; 39: 129-34.
-
(2002)
Hypertension
, vol.39
, pp. 129-134
-
-
Nishiyama, A.1
Seth, D.M.2
Navar, L.G.3
-
22
-
-
0026598246
-
Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium
-
Abou-Samra AB, Jüppner H, Force T, et al., Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci USA. 1992; 89 (7): 2732-6.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, Issue.7
, pp. 2732-2736
-
-
Abou-Samra, A.B.1
Jüppner, H.2
Force, T.3
-
23
-
-
0024423108
-
Parathyroid hormone acute vascular effect is mediated by decreased Ca2+ uptake and enhanced cAMP level
-
Schleiffer R, Bergmann C, Pernot F, Gairard A., Parathyroid hormone acute vascular effect is mediated by decreased Ca2+ uptake and enhanced cAMP level. Mol Cell Endocrinol. 1989; 67 (1): 63-71.
-
(1989)
Mol Cell Endocrinol
, vol.67
, Issue.1
, pp. 63-71
-
-
Schleiffer, R.1
Bergmann, C.2
Pernot, F.3
Gairard, A.4
-
24
-
-
0036150953
-
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene
-
Yoshida T, Fujimori T, Nabeshima Y., Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene. Endocrinology. 2002; 143 (2): 683-9.
-
(2002)
Endocrinology
, vol.143
, Issue.2
, pp. 683-689
-
-
Yoshida, T.1
Fujimori, T.2
Nabeshima, Y.3
-
25
-
-
0035923640
-
Parathyroid hormone regulates 25-hydroxyvitamin D(3)-24-hydroxylase mRNA by altering its stability
-
Zierold C, Mings JA, DeLuca HF., Parathyroid hormone regulates 25-hydroxyvitamin D(3)-24-hydroxylase mRNA by altering its stability. Proc Natl Acad Sci USA. 2001; 98 (24): 13572-6.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.24
, pp. 13572-13576
-
-
Zierold, C.1
Mings, J.A.2
DeLuca, H.F.3
-
26
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o M, Matsumura Y, Aizawa H, et al., Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature. 1997; 390 (6655): 45-51.
-
(1997)
Nature
, vol.390
, Issue.6655
, pp. 45-51
-
-
Kuro-O, M.1
Matsumura, Y.2
Aizawa, H.3
-
27
-
-
0033624656
-
1alpha-Hydroxylase and the action of Vitamin D
-
Hewison M, Zehnder D, Bland R, Stewart PM., 1alpha-Hydroxylase and the action of vitamin D. J Mol Endocrinol. 2000; 25 (2): 141-8.
-
(2000)
J Mol Endocrinol
, vol.25
, Issue.2
, pp. 141-148
-
-
Hewison, M.1
Zehnder, D.2
Bland, R.3
Stewart, P.M.4
-
28
-
-
84938965150
-
Unexpected action of lanthanum carbonate
-
Takenaka T, Yamanaka T, Yoshida M, Suzuki H., Unexpected action of lanthanum carbonate. Osteoporos Int. 2015; 26 (9): 2385-6.
-
(2015)
Osteoporos Int
, vol.26
, Issue.9
, pp. 2385-2386
-
-
Takenaka, T.1
Yamanaka, T.2
Yoshida, M.3
Suzuki, H.4
-
29
-
-
33646578195
-
Regulation of fibroblast growth factor-23 signaling by klotho
-
Kurosu H, Ogawa Y, Miyoshi M, et al., Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem. 2006; 281 (10): 6120-3.
-
(2006)
J Biol Chem
, vol.281
, Issue.10
, pp. 6120-6123
-
-
Kurosu, H.1
Ogawa, Y.2
Miyoshi, M.3
-
30
-
-
0035793430
-
Structural characterization of the circulating soluble FGF receptors reveals multiple isoforms generated by secretion and ectodomain shedding
-
Hanneken A,. Structural characterization of the circulating soluble FGF receptors reveals multiple isoforms generated by secretion and ectodomain shedding. FEBS Lett. 2001; 489 (2-3): 176-81.
-
(2001)
FEBS Lett
, vol.489
, Issue.23
, pp. 176-181
-
-
Hanneken, A.1
|