Acute hypotension induced by aortic clamp vs. PTH provokes distinct proximal tubule Na+ transporter redistribution patterns

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 287, Issue 4 56-4, 2004, Pages

  Leong, Patrick K K ^a   Yang, Li E ^a   Lin, Harrison W ^a   Holstein Rathlou, Niels H ^b   McDonough, Alicia A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Blood pressure; Glomerular filtration rate; Kidney; Lithium clearance; Parathyroid hormone; Rats

Indexed keywords

COTRANSPORTER; LITHIUM; PARATHYROID HORMONE; SODIUM PROTON EXCHANGE PROTEIN; SORBITOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CLAMPING; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENSITY GRADIENT; DIURESIS; DRUG MEGADOSE; GLOMERULUS FILTRATION RATE; HYPOTENSION; IMMUNOBLOTTING; KIDNEY BLOOD FLOW; KIDNEY PROXIMAL TUBULE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM ABSORPTION; URINE VOLUME;

ANIMALS; AORTA, THORACIC; CARRIER PROTEINS; CENTRIFUGATION, DENSITY GRADIENT; CONSTRICTION; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; GLOMERULAR FILTRATION RATE; HYPOTENSION; IMMUNOBLOTTING; KIDNEY FUNCTION TESTS; KIDNEY TUBULES, PROXIMAL; MALE; PARATHYROID HORMONE; RATS; RATS, SPRAGUE-DAWLEY; RENAL CIRCULATION; SODIUM; SODIUM-HYDROGEN ANTIPORTER; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE IIA; SYMPORTERS;

EID: 4644245343     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00180.2004     Document Type: Article

References (50)

1. Agus ZS, Gardner LB, Beck LH, and Goldberg M. Effects of parathyroid hormone on renal tubular reabsorption of calcium, sodium, and phosphate. Am J Physiol 224: 1143-1148, 1973.
2. Bossert WH and Schwartz WB. Relation of pressure and flow to control of sodium reabsorption in the proximal tubule. Am J Physiol 213: 793-802, 1967.
3. Brenner BM, Bennett CM, and Berliner RW. The relationship between glomerular filtration rate and sodium reabsorption by the proximal tubule of the rat nephron. J Clin Invest 47: 1358-1374, 1968.
4. Chou CL and Marsh DJ. Role of proximal convoluted tubule in pressure diuresis in the rat. Am J Physiol Renal Fluid Electrolyte Physiol 251: F283-F289, 1986.
5. + exchanger NHE3 by parathyroid hormone via NHE3 phosphorylation and dynamin-dependent endocytosis. J Biol Chem 275: 31601-31608, 2000.
6. i cotransport in rat kidney: localization by RT-PCR and immunohistochemistry. Am J Physiol Renal Fluid Electrolyte Physiol 266: F767-F774, 1994.
7. Deng X, Welch WJ, and Wilcox CS. Renal vasoconstriction during inhibition of NO synthase: effects of dietary salt. Kidney Int 46: 639-646, 1994.
8. Dresser TP, Lynch RE, Schneider EG, and Knox FG. Effect of increases in blood pressure on pressure and reabsorption in the proximal tubule. Am J Physiol 220: 444-447, 1971.
9. Fan L, Wiederkehr MR, Collazo R, Wang H, Crowder LA, and Moe OW. Dual mechanisms of regulation of Na/H exchanger NHE-3 by parathyroid hormone in rat kidney. J Biol Chem 274: 11289-11295, 1999.
10. + exchangers. Ann NY Acad Sci 976: 248-258, 2002.
11. Hensley CB, Bradley ME, and Mircheff AK. Parathyroid hormone-induced translocation of Na-H antiporters in rat proximal tubules. Am J Physiol Cell Physiol 257: C637-C645, 1989.
12. Kempson SA, Lotscher M, Kaissling B, Biber J, Murer H, and Levi M. Parathyroid hormone action on phosphate transporter mRNA and protein in rat renal proximal tubules. Am J Physiol Renal Fluid Electrolyte Physiol 268: F784-F791, 1995.
13. Koch KM, Aynedjian HS, and Bank N. Effect of acute hypertension on sodium reabsorption by the proximal tubule. J Clin Invest 47: 1696-1709, 1968.
14. Landwehr DM, Schnermann J, Klose RM, and Giebisch G. Effect of reduction in filtration rate on renal tubular sodium and water reabsorption. Am J Physiol 215: 687-695, 1968.
15. Leong PK, Yang LE, Holstein-Rathlou NH, and McDonough AA. Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertension. Am J Physiol Renal Physiol 283: F1142-F1150, 2002.
16. Liebau G, Levine DZ, and Thurau K. Micropuncture studies on the dog kidney. I. The response of the proximal tubule to changes in systemic blood pressure within and below the autoregulatory range. Pflügers Arch 304: 57-68, 1968.
17. Lorenz JN and Gruenstein E. A simple, nonradioactive method for evaluating single-nephron filtration rate using FITC-inulin. Am J Physiol Renal Physiol 276: F172-F177, 1999.
18. i-cotransporter by parathyroid hormone: immunohistochemistry. Kidney Int 49: 1010-1011, 1996.
19. i cotransporter in response to parathyroid hormone involves microtubule rearrangement. J Clin Invest 104: 483-494. 1999.
20. i cotransport. Proc Natl Acad Sci USA 90: 5979-5983, 1993.
21. Malmstrom K and Murer H. Parathyroid hormone regulates phosphate transport in OK cells via an irreversible inactivation of a membrane protein. FEBS Lett 216: 257-260, 1987.
22. Moe OW. Acute regulation of proximal tubule apical membrane Na/H exchanger NHE-3: role of phosphorylation, protein trafficking, and regulatory factors. J Am Soc Nephrol 10: 2412-2425, 1999.
23. i. Am J Physiol Renal Physiol 277: F676-F684, 1999.
24. Murer H, Hernando N, Forster I, and Biber J. Molecular aspects in the regulation of renal inorganic phosphate reabsorption: the type IIa sodium/ inorganic phosphate co-transporter as the key player. Curr Opin Nephrol Hypertens 10: 555-561, 2001.
25. Murer H, Hernando N, Forster I, and Biber J. Regulation of Na/Pi transporter in the proximal tubule. Annu Rev Physiol 65: 531-542, 2003.
26. Navar LG, Bell PD, and Burke TJ. Autoregulatory responses of superficial nephrons and their association with sodium excretion during arterial pressure alterations in the dog. Circ Res 41: 487-496, 1977.
27. Navar LG, Paul RV, Carmines PK, Chou CL, and Marsh DJ. Intrarenal mechanisms mediating pressure natriuresis: role of angiotensin and prostaglandins. Fed Proc 45: 2885-2891, 1986.
28. Osgood RW, Lameire NH, Sorkin MI, and Stein JH. Effect of aortic clamping on proximal reabsorption and sodium excretion in the rat. Am J Physiol Renal Fluid Electrolyte Physiol 232: F92-F96, 1977.
29. Pfister MF, Ruf I, Stange G, Ziegler U, Lederer E, Biber J, and Murer II. Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter. Proc Natl Acad Sci USA 95: 1909-1914, 1998.
30. + antiporter in rat proximal tubule bicarbonate absorption. J Clin Invest 80: 970-978, 1987.
31. + antiport in rat proximal tubule NaCl absorption. Am J Physiol Renal Fluid Electrolyte Physiol 255: F461-F465, 1988.
32. Rambausek M, Ritz E, Rascher W, Kreusser W, Mann JF, Kreye VA, and Mehls O. Vascular effects of parathyroid hormone (PTH). Adv Exp Med Biol 151: 619-632, 1982.
33. Roca-Cusachs A, DiPette DJ, and Nickols GA. Regional and systemic hemodynamic effects of parathyroid hormone-related protein: preservation of cardiac function and coronary and renal flow with reduced blood pressure. J Pharmacol Exp Ther 256: 110-118, 1991.
34. Rosivall L, Youngblood P, and Navar LG. Renal autoregulatory efficiency during angiotensin-converting enzyme inhibition in dogs on a low sodium diet. Renal Physiol 9: 18-28, 1986.
35. Schneider EG. Effect of parathyroid hormone secretion on sodium reabsorption by the proximal tubule. Am J Physiol 229: 1170-1173, 1975.
36. Segawa H, Kaneko I, Takahashi A, Kuwahata M, Ito M, Ohkido I, Tatsumi S, and Miyamoto K. Growth-related renal type II Na/Pi cotransporter. J Biol Chem 277: 19665-19672, 2002.
37. Selkurt EE, Hall PW, and Spencer MP. Influence of graded arterial pressure decrement on renal clearance of creatinine, p-aminohippurate and sodium. J Clin Invest 159: 369-378, 1949.
38. Shipley RE and Study RS. Changes in renal blood flow, extraction of inulin, glomerular filtration rate, tissue pressure and urine flow with acute alterations of renal artery blood pressure. J Clin Invest 167: 676-688, 1951.
39. Smith DM. A system to regulate aortic pressure in the rat. J Appl Physiol 38: 356-357, 1975.
40. Thomsen K. Lithium clearance: a new method for determining proximal and distal tubular reabsorption of sodium and water. Nephron 37: 217-223, 1984.
41. i cotransporter by PTH: immunogold electron microscopy. Am J Physiol Renal Physiol 278: F148-F154, 2000.
42. i cotransporter. Am J Physiol Renal Physiol 278: F792-F798, 2000.
43. Wang CT, Chin SY, and Navar LG. Impairment of pressure-natriuresis and renal autoregulation in ANG II-infused hypertensive rats. Am J Physiol Renal Physiol 279: F319-F325, 2000.
44. Yang L, Leong PK, Chen JO, Patel N, Hamm-Alvarez SF, and McDonough AA. Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity. Am J Physiol Renal Physiol 282: F730-F740, 2002.
45. + exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension. Am J Physiol Renal Physiol 275: F565-F575, 1998.
46. Zhang Y, Magyar CE, Norian JM, Holstein-Rathlou NH, Mircheff AK, and McDonough AA. Reversible effects of acute hypertension on proximal tubule sodium transporters. Am J Physiol Cell Physiol 274: C1090-C1100, 1998.
47. Zhang Y, Mircheff AK, Hensley CB, Magyar CE, Warnock DG, Chambrey R, Yip KP, Marsh DJ, Holstein-Rathlou NH, and McDonough AA. Rapid redistribution and inhibition of renal sodium transporters during acute pressure natriuresis. Am J Physiol Renal Fluid Electrolyte Physiol 270: F1004-F1014, 1996.
48. Zhang Y, Norian JM, Magyar CE, Holstein-Rathlou NH, Mircheff AK, and McDonough AA. In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition. Am J Physiol Renal Physiol 276: F711-F719, 1999.
49. Zhang YB, Magyar CE, Holstein-Rathlou NH, and McDonough AA. The cytochrome P-50 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension. J Am Soc Nephrol 9: 531-537, 1998.
50. Zhou H, Leaver DD, Moseley JM, Kemp B, Ebeling PR, and Martin TJ. Actions of parathyroid hormone-related protein on the rat kidney in vivo. J Endocrinol 122: 229-235, 1989.