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Volumn 12, Issue 2, 2016, Pages

Transcriptome-Wide Analysis of Hepatitis B Virus-Mediated Changes to Normal Hepatocyte Gene Expression

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN E; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; GREEN FLUORESCENT PROTEIN; MICRORNA; TRANSCRIPTOME;

EID: 84959457692     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005438     Document Type: Article
Times cited : (47)

References (115)
  • 1
    • 84860287080 scopus 로고    scopus 로고
    • Epidemiology of viral hepatitis and hepatocellular carcinoma
    • 22537432e1
    • El-Serag HB, Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology. 2012;142(6):1264–73 e1. doi: 10.1053/j.gastro.2011.12.06122537432
    • (2012) Gastroenterology , vol.142 , Issue.6 , pp. 1264-1273
    • El-Serag, H.B.1
  • 2
    • 0042968962 scopus 로고    scopus 로고
    • Molecular viral oncology of hepatocellular carcinoma
    • 12910247, Epub 2003/08/12
    • Block TM, Mehta AS, Fimmel CJ, Jordan R, Molecular viral oncology of hepatocellular carcinoma. Oncogene. 2003;22(33):5093–107. Epub 2003/08/12. 12910247
    • (2003) Oncogene , vol.22 , Issue.33 , pp. 5093-5107
    • Block, T.M.1    Mehta, A.S.2    Fimmel, C.J.3    Jordan, R.4
  • 3
    • 84860304268 scopus 로고    scopus 로고
    • Effectiveness of hepatitis B treatment in clinical practice
    • 22537444e1
    • Scaglione SJ, Lok AS, Effectiveness of hepatitis B treatment in clinical practice. Gastroenterology. 2012;142(6):1360–8 e1. doi: 10.1053/j.gastro.2012.01.04422537444
    • (2012) Gastroenterology , vol.142 , Issue.6 , pp. 1360-1368
    • Scaglione, S.J.1    Lok, A.S.2
  • 4
    • 84959507186 scopus 로고    scopus 로고
    • GLOBOCAN 2012 v1.0 [Internet]. IARC CancerBase No. 11. 2013
    • GLOBOCAN 2012 v1.0 [Internet]. IARC CancerBase No. 11. 2013. Available from: http://globocan.iarc.fr.
  • 7
    • 77649112712 scopus 로고    scopus 로고
    • The hepatitis B virus X protein modulates hepatocyte proliferation pathways to stimulate viral replication
    • 20053744, Epub 2010/01/08
    • Gearhart TL, Bouchard MJ, The hepatitis B virus X protein modulates hepatocyte proliferation pathways to stimulate viral replication. Journal of virology. 2010;84(6):2675–86. Epub 2010/01/08. doi: 10.1128/JVI.02196-0920053744
    • (2010) Journal of virology , vol.84 , Issue.6 , pp. 2675-2686
    • Gearhart, T.L.1    Bouchard, M.J.2
  • 8
    • 78650575534 scopus 로고    scopus 로고
    • The hepatitis B virus HBx protein modulates cell cycle regulatory proteins in cultured primary human hepatocytes
    • 20934470, Epub 2010/10/12
    • Gearhart TL, Bouchard MJ, The hepatitis B virus HBx protein modulates cell cycle regulatory proteins in cultured primary human hepatocytes. Virus research. 2011;155(1):363–7. Epub 2010/10/12. doi: 10.1016/j.virusres.2010.09.02320934470
    • (2011) Virus research , vol.155 , Issue.1 , pp. 363-367
    • Gearhart, T.L.1    Bouchard, M.J.2
  • 9
    • 0035048023 scopus 로고    scopus 로고
    • Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway
    • 11287574
    • Bouchard M, Giannakopoulos S, Wang EH, Tanese N, Schneider RJ, Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway. Journal of virology. 2001;75(9):4247–57. 11287574
    • (2001) Journal of virology , vol.75 , Issue.9 , pp. 4247-4257
    • Bouchard, M.1    Giannakopoulos, S.2    Wang, E.H.3    Tanese, N.4    Schneider, R.J.5
  • 11
    • 84869133121 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 2 phosphorylates s/t-p sites in the hepadnavirus core protein C-terminal domain and is incorporated into viral capsids
    • 22951823
    • Ludgate L, Ning X, Nguyen DH, Adams C, Mentzer L, Hu J, Cyclin-dependent kinase 2 phosphorylates s/t-p sites in the hepadnavirus core protein C-terminal domain and is incorporated into viral capsids. Journal of virology. 2012;86(22):12237–50. doi: 10.1128/JVI.01218-1222951823
    • (2012) Journal of virology , vol.86 , Issue.22 , pp. 12237-12250
    • Ludgate, L.1    Ning, X.2    Nguyen, D.H.3    Adams, C.4    Mentzer, L.5    Hu, J.6
  • 12
    • 0035812298 scopus 로고    scopus 로고
    • Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway
    • 11574165
    • Ahn JY, Chung EY, Kwun HJ, Jang KL, Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway. Gene. 2001;275(1):163–8. 11574165
    • (2001) Gene , vol.275 , Issue.1 , pp. 163-168
    • Ahn, J.Y.1    Chung, E.Y.2    Kwun, H.J.3    Jang, K.L.4
  • 13
    • 34547593907 scopus 로고    scopus 로고
    • Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis
    • 17512084–
    • Chin R, Earnest-Silveira L, Koeberlein B, Franz S, Zentgraf H, Dong X, et al. Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis. Journal of hepatology. 2007;47(3):325–37. 17512084
    • (2007) Journal of hepatology , vol.47 , Issue.3 , pp. 325-337
    • Chin, R.1    Earnest-Silveira, L.2    Koeberlein, B.3    Franz, S.4    Zentgraf, H.5    Dong, X.6
  • 14
    • 0037040927 scopus 로고    scopus 로고
    • Hepatitis B virus X protein differentially regulates cell cycle progression in X-transforming versus nontransforming hepatocyte (AML12) cell lines
    • 11756437
    • Lee S, Tarn C, Wang WH, Chen S, Hullinger RL, Andrisani OM, Hepatitis B virus X protein differentially regulates cell cycle progression in X-transforming versus nontransforming hepatocyte (AML12) cell lines. The Journal of biological chemistry. 2002;277(10):8730–40. 11756437
    • (2002) The Journal of biological chemistry , vol.277 , Issue.10 , pp. 8730-8740
    • Lee, S.1    Tarn, C.2    Wang, W.H.3    Chen, S.4    Hullinger, R.L.5    Andrisani, O.M.6
  • 15
    • 33846333916 scopus 로고    scopus 로고
    • HBx-dependent cell cycle deregulation involves interaction with cyclin E/A-cdk2 complex and destabilization of p27Kip1
    • 16939421
    • Mukherji A, Janbandhu VC, Kumar V, HBx-dependent cell cycle deregulation involves interaction with cyclin E/A-cdk2 complex and destabilization of p27Kip1. The Biochemical journal. 2007;401(1):247–56. 16939421
    • (2007) The Biochemical journal , vol.401 , Issue.1 , pp. 247-256
    • Mukherji, A.1    Janbandhu, V.C.2    Kumar, V.3
  • 16
    • 84907283865 scopus 로고    scopus 로고
    • Cyclin D2 plays a regulatory role in HBV replication
    • 24992041
    • Song CL, Ren JH, Ran LK, Li YG, Li XS, Chen X, et al. Cyclin D2 plays a regulatory role in HBV replication. Virology. 2014;462–463:149–57. doi: 10.1016/j.virol.2014.05.02724992041
    • (2014) Virology , vol.462-463 , pp. 149-157
    • Song, C.L.1    Ren, J.H.2    Ran, L.K.3    Li, Y.G.4    Li, X.S.5    Chen, X.6
  • 17
    • 84934441046 scopus 로고    scopus 로고
    • Cell cycle regulation during viral infection
    • 24906315
    • Bagga S, Bouchard MJ, Cell cycle regulation during viral infection. Methods Mol Biol. 2014;1170:165–227. doi: 10.1007/978-1-4939-0888-2_1024906315
    • (2014) Methods Mol Biol , vol.1170 , pp. 165-227
    • Bagga, S.1    Bouchard, M.J.2
  • 18
    • 85026968190 scopus 로고    scopus 로고
    • Bouchard MJ
    • Casciano J, Bagga S, Yang B, Bouchard MJ. Modulation of cell proliferation pathways by the hepatitis B virus X protein: a potential contributor to the development of hepatocellular carcinoma. 2011.
    • (2011)
    • Casciano, J.1    Bagga, S.2    Yang, B.3
  • 19
    • 35348858953 scopus 로고    scopus 로고
    • Regulation of hepatitis B virus replication by the phosphatidylinositol 3-kinase-akt signal transduction pathway
    • 17609269, .Epub 2007/07/05
    • Guo H, Zhou T, Jiang D, Cuconati A, Xiao GH, Block TM, et al. Regulation of hepatitis B virus replication by the phosphatidylinositol 3-kinase-akt signal transduction pathway. Journal of virology. 2007;81(18):10072–80. Epub 2007/07/05. 17609269
    • (2007) Journal of virology , vol.81 , Issue.18 , pp. 10072-10080
    • Guo, H.1    Zhou, T.2    Jiang, D.3    Cuconati, A.4    Xiao, G.H.5    Block, T.M.6
  • 20
    • 85026972060 scopus 로고    scopus 로고
    • The Hepatitis B Virus HBx protein activates AKT to simultaneously regulate HBV replication and hepatocyte survival
    • Rawat S, Bouchard M, The Hepatitis B Virus HBx protein activates AKT to simultaneously regulate HBV replication and hepatocyte survival. Journal of virology. 2014.
    • (2014) Journal of virology
    • Rawat, S.1    Bouchard, M.2
  • 21
    • 84929309929 scopus 로고    scopus 로고
    • Hepatitis B Virus Pre-S2 Mutant Induces Aerobic Glycolysis through Mammalian Target of Rapamycin Signal Cascade
    • 25909713
    • Teng CF, Hsieh WC, Wu HC, Lin YJ, Tsai HW, Huang W, et al. Hepatitis B Virus Pre-S2 Mutant Induces Aerobic Glycolysis through Mammalian Target of Rapamycin Signal Cascade. PloS one. 2015;10(4):e0122373. doi: 10.1371/journal.pone.012237325909713
    • (2015) PloS one , vol.10 , Issue.4 , pp. 122373
    • Teng, C.F.1    Hsieh, W.C.2    Wu, H.C.3    Lin, Y.J.4    Tsai, H.W.5    Huang, W.6
  • 23
    • 84929211544 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells
    • Zhu M, Guo J, Li W, Lu Y, Fu S, Xie X, et al. Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells. Oncotarget. 2015.
    • (2015) Oncotarget
    • Zhu, M.1    Guo, J.2    Li, W.3    Lu, Y.4    Fu, S.5    Xie, X.6
  • 24
    • 80053331166 scopus 로고    scopus 로고
    • Novel feedback inhibition of surface antigen synthesis by mammalian target of rapamycin (mTOR) signal and its implication for hepatitis B virus tumorigenesis and therapy
    • 21735472
    • Teng CF, Wu HC, Tsai HW, Shiah HS, Huang W, Su IJ, Novel feedback inhibition of surface antigen synthesis by mammalian target of rapamycin (mTOR) signal and its implication for hepatitis B virus tumorigenesis and therapy. Hepatology. 2011;54(4):1199–207. doi: 10.1002/hep.2452921735472
    • (2011) Hepatology , vol.54 , Issue.4 , pp. 1199-1207
    • Teng, C.F.1    Wu, H.C.2    Tsai, H.W.3    Shiah, H.S.4    Huang, W.5    Su, I.J.6
  • 25
    • 33646193810 scopus 로고    scopus 로고
    • Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication
    • 16611900
    • Bouchard MJ, Wang L, Schneider RJ, Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication. Journal of virology. 2006;80(9):4406–14. 16611900
    • (2006) Journal of virology , vol.80 , Issue.9 , pp. 4406-4414
    • Bouchard, M.J.1    Wang, L.2    Schneider, R.J.3
  • 26
    • 0035860752 scopus 로고    scopus 로고
    • Hepatitis B virus X protein differentially activates RAS-RAF-MAPK and JNK pathways in X-transforming versus non-transforming AML12 hepatocytes
    • 11461911
    • Tarn C, Lee S, Hu Y, Ashendel C, Andrisani OM, Hepatitis B virus X protein differentially activates RAS-RAF-MAPK and JNK pathways in X-transforming versus non-transforming AML12 hepatocytes. The Journal of biological chemistry. 2001;276(37):34671–80. 11461911
    • (2001) The Journal of biological chemistry , vol.276 , Issue.37 , pp. 34671-34680
    • Tarn, C.1    Lee, S.2    Hu, Y.3    Ashendel, C.4    Andrisani, O.M.5
  • 27
    • 84984539055 scopus 로고    scopus 로고
    • Role of microRNAs in hepatitis B virus replication and pathogenesis
    • 21565290, Epub 2011/05/14
    • Liu WH, Yeh SH, Chen PJ, Role of microRNAs in hepatitis B virus replication and pathogenesis. Biochimica et biophysica acta. 2011;1809(11–12):678–85. Epub 2011/05/14. doi: 10.1016/j.bbagrm.2011.04.00821565290
    • (2011) Biochimica et biophysica acta , vol.1809 , Issue.11-12 , pp. 678-685
    • Liu, W.H.1    Yeh, S.H.2    Chen, P.J.3
  • 28
    • 84887393514 scopus 로고    scopus 로고
    • Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases
    • 24212236
    • Thirion M, Ochiya T, Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases. Viruses. 2013;5(11):2690–703. doi: 10.3390/v511269024212236
    • (2013) Viruses , vol.5 , Issue.11 , pp. 2690-2703
    • Thirion, M.1    Ochiya, T.2
  • 29
    • 84936743104 scopus 로고    scopus 로고
    • Hepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseases. World journal of gastroenterology
    • 26139985
    • Lamontagne J, Steel LF, Bouchard MJ, Hepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseases. World journal of gastroenterology: WJG. 2015;21(24):7375–99. doi: 10.3748/wjg.v21.i24.737526139985
    • (2015) WJG , vol.21 , Issue.24 , pp. 7375-7399
    • Lamontagne, J.1    Steel, L.F.2    Bouchard, M.J.3
  • 30
    • 84865567558 scopus 로고    scopus 로고
    • Transcriptomic analysis of the woodchuck model of chronic hepatitis B
    • 22431061–
    • Fletcher SP, Chin DJ, Ji Y, Iniguez AL, Taillon B, Swinney DC, et al. Transcriptomic analysis of the woodchuck model of chronic hepatitis B. Hepatology. 2012;56(3):820–30. doi: 10.1002/hep.2573022431061
    • (2012) Hepatology , vol.56 , Issue.3 , pp. 820-830
    • Fletcher, S.P.1    Chin, D.J.2    Ji, Y.3    Iniguez, A.L.4    Taillon, B.5    Swinney, D.C.6
  • 31
    • 80054771709 scopus 로고    scopus 로고
    • RNA-Seq analyses generate comprehensive transcriptomic landscape and reveal complex transcript patterns in hepatocellular carcinoma
    • 22043308
    • Huang Q, Lin B, Liu H, Ma X, Mo F, Yu W, et al. RNA-Seq analyses generate comprehensive transcriptomic landscape and reveal complex transcript patterns in hepatocellular carcinoma. PloS one. 2011;6(10):e26168. doi: 10.1371/journal.pone.002616822043308
    • (2011) PloS one , vol.6 , Issue.10 , pp. 26168
    • Huang, Q.1    Lin, B.2    Liu, H.3    Ma, X.4    Mo, F.5    Yu, W.6
  • 32
    • 84907492839 scopus 로고    scopus 로고
    • A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • 24510058
    • Yu Y, Fuscoe JC, Zhao C, Guo C, Jia M, Qing T, et al. A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages. Nature communications. 2014;5:3230. doi: 10.1038/ncomms423024510058
    • (2014) Nature communications , vol.5 , pp. 3230
    • Yu, Y.1    Fuscoe, J.C.2    Zhao, C.3    Guo, C.4    Jia, M.5    Qing, T.6
  • 33
    • 84878632967 scopus 로고    scopus 로고
    • Characterization of the rat developmental liver transcriptome
    • 23429212–
    • Chapple RH, Tizioto PC, Wells KD, Givan SA, Kim J, McKay SD, et al. Characterization of the rat developmental liver transcriptome. Physiol Genomics. 2013;45(8):301–11. doi: 10.1152/physiolgenomics.00128.201223429212
    • (2013) Physiol Genomics , vol.45 , Issue.8 , pp. 301-311
    • Chapple, R.H.1    Tizioto, P.C.2    Wells, K.D.3    Givan, S.A.4    Kim, J.5    McKay, S.D.6
  • 34
    • 84895524096 scopus 로고    scopus 로고
    • RNA-seq based transcriptome analysis of hepatitis E virus (HEV) and hepatitis B virus (HBV) replicon transfected Huh-7 cells
    • 24505321
    • Jagya N, Varma SP, Thakral D, Joshi P, Durgapal H, Panda SK, RNA-seq based transcriptome analysis of hepatitis E virus (HEV) and hepatitis B virus (HBV) replicon transfected Huh-7 cells. PloS one. 2014;9(2):e87835. doi: 10.1371/journal.pone.008783524505321
    • (2014) PloS one , vol.9 , Issue.2 , pp. 87835
    • Jagya, N.1    Varma, S.P.2    Thakral, D.3    Joshi, P.4    Durgapal, H.5    Panda, S.K.6
  • 35
    • 84945935564 scopus 로고    scopus 로고
    • Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep whole-transcriptome sequencing
    • .. Epub 2013/10/22
    • Lin KT, Shann YJ, Chau GY, Hsu CN, Huang CY, Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep whole-transcriptome sequencing. Oncogene. 2013. Epub 2013/10/22.
    • (2013) Oncogene
    • Lin, K.T.1    Shann, Y.J.2    Chau, G.Y.3    Hsu, C.N.4    Huang, C.Y.5
  • 36
    • 84876453615 scopus 로고    scopus 로고
    • RNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated rats
    • 23630614
    • Merrick BA, Phadke DP, Auerbach SS, Mav D, Stiegelmeyer SM, Shah RR, et al. RNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated rats. PloS one. 2013;8(4):e61768. doi: 10.1371/journal.pone.006176823630614
    • (2013) PloS one , vol.8 , Issue.4 , pp. 61768
    • Merrick, B.A.1    Phadke, D.P.2    Auerbach, S.S.3    Mav, D.4    Stiegelmeyer, S.M.5    Shah, R.R.6
  • 37
    • 84925685106 scopus 로고    scopus 로고
    • RNA-Seq gene expression profiling of HepG2 cells: the influence of experimental factors and comparison with liver tissue
    • 25511409
    • Tyakht AV, Ilina EN, Alexeev DG, Ischenko DS, Gorbachev AY, Semashko TA, et al. RNA-Seq gene expression profiling of HepG2 cells: the influence of experimental factors and comparison with liver tissue. BMC genomics. 2014;15:1108. doi: 10.1186/1471-2164-15-110825511409
    • (2014) BMC genomics , vol.15 , pp. 1108
    • Tyakht, A.V.1    Ilina, E.N.2    Alexeev, D.G.3    Ischenko, D.S.4    Gorbachev, A.Y.5    Semashko, T.A.6
  • 38
    • 84872035154 scopus 로고    scopus 로고
    • Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B
    • 22806943–
    • Fletcher SP, Chin DJ, Cheng DT, Ravindran P, Bitter H, Gruenbaum L, et al. Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B. Hepatology. 2013;57(1):13–22. doi: 10.1002/hep.2595422806943
    • (2013) Hepatology , vol.57 , Issue.1 , pp. 13-22
    • Fletcher, S.P.1    Chin, D.J.2    Cheng, D.T.3    Ravindran, P.4    Bitter, H.5    Gruenbaum, L.6
  • 39
    • 0019966544 scopus 로고
    • Growth of human hepatoma cells lines with differentiated functions in chemically defined medium
    • 6286115
    • Nakabayashi H, Taketa K, Miyano K, Yamane T, Sato J, Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer research. 1982;42(9):3858–63. 6286115
    • (1982) Cancer research , vol.42 , Issue.9 , pp. 3858-3863
    • Nakabayashi, H.1    Taketa, K.2    Miyano, K.3    Yamane, T.4    Sato, J.5
  • 40
    • 0019332750 scopus 로고
    • Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
    • 6248960
    • Knowles BB, Howe CC, Aden DP, Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science. 1980;209(4455):497–9. 6248960
    • (1980) Science , vol.209 , Issue.4455 , pp. 497-499
    • Knowles, B.B.1    Howe, C.C.2    Aden, D.P.3
  • 41
    • 0038172423 scopus 로고    scopus 로고
    • Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems
    • 12657743–
    • Boess F, Kamber M, Romer S, Gasser R, Muller D, Albertini S, et al. Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems. Toxicol Sci. 2003;73(2):386–402. 12657743
    • (2003) Toxicol Sci , vol.73 , Issue.2 , pp. 386-402
    • Boess, F.1    Kamber, M.2    Romer, S.3    Gasser, R.4    Muller, D.5    Albertini, S.6
  • 42
    • 0023755464 scopus 로고
    • Hepatitis B virus infection of adult human hepatocytes cultured in the presence of dimethyl sulfoxide
    • 3172341–
    • Gripon P, Diot C, Theze N, Fourel I, Loreal O, Brechot C, et al. Hepatitis B virus infection of adult human hepatocytes cultured in the presence of dimethyl sulfoxide. Journal of virology. 1988;62(11):4136–43. 3172341
    • (1988) Journal of virology , vol.62 , Issue.11 , pp. 4136-4143
    • Gripon, P.1    Diot, C.2    Theze, N.3    Fourel, I.4    Loreal, O.5    Brechot, C.6
  • 43
    • 0343026658 scopus 로고    scopus 로고
    • Efficient infection of primary tupaia hepatocytes with purified human and woolly monkey hepatitis B virus
    • 11333889
    • Kock J, Nassal M, MacNelly S, Baumert TF, Blum HE, von Weizsacker F, Efficient infection of primary tupaia hepatocytes with purified human and woolly monkey hepatitis B virus. Journal of virology. 2001;75(11):5084–9. 11333889
    • (2001) Journal of virology , vol.75 , Issue.11 , pp. 5084-5089
    • Kock, J.1    Nassal, M.2    MacNelly, S.3    Baumert, T.F.4    Blum, H.E.5    von Weizsacker, F.6
  • 45
  • 46
    • 65349104743 scopus 로고    scopus 로고
    • Hepatitis B virus X protein modulates apoptosis in primary rat hepatocytes by regulating both NF-kappaB and the mitochondrial permeability transition pore
    • 19279112, Epub 2009/03/13
    • Clippinger AJ, Gearhart TL, Bouchard MJ, Hepatitis B virus X protein modulates apoptosis in primary rat hepatocytes by regulating both NF-kappaB and the mitochondrial permeability transition pore. Journal of virology. 2009;83(10):4718–31. Epub 2009/03/13. doi: 10.1128/JVI.02590-0819279112
    • (2009) Journal of virology , vol.83 , Issue.10 , pp. 4718-4731
    • Clippinger, A.J.1    Gearhart, T.L.2    Bouchard, M.J.3
  • 47
    • 0035033218 scopus 로고    scopus 로고
    • Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: crossing the species barrier
    • 11333892
    • Sprinzl MF, Oberwinkler H, Schaller H, Protzer U, Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: crossing the species barrier. Journal of virology. 2001;75(11):5108–18. 11333892
    • (2001) Journal of virology , vol.75 , Issue.11 , pp. 5108-5118
    • Sprinzl, M.F.1    Oberwinkler, H.2    Schaller, H.3    Protzer, U.4
  • 48
    • 77956941978 scopus 로고    scopus 로고
    • Replication of the hepatitis B virus requires a calcium-dependent HBx-induced G1 phase arrest of hepatocytes
    • 20719353, Epub 2010/08/20
    • Gearhart TL, Bouchard MJ, Replication of the hepatitis B virus requires a calcium-dependent HBx-induced G1 phase arrest of hepatocytes. Virology. 2010;407(1):14–25. Epub 2010/08/20. doi: 10.1016/j.virol.2010.07.04220719353
    • (2010) Virology , vol.407 , Issue.1 , pp. 14-25
    • Gearhart, T.L.1    Bouchard, M.J.2
  • 49
    • 0027941175 scopus 로고
    • Woodchuck hepatitis virus infections: very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte
    • 7914548
    • Kajino K, Jilbert AR, Saputelli J, Aldrich CE, Cullen J, Mason WS, Woodchuck hepatitis virus infections: very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte. Journal of virology. 1994;68(9):5792–803. 7914548
    • (1994) Journal of virology , vol.68 , Issue.9 , pp. 5792-5803
    • Kajino, K.1    Jilbert, A.R.2    Saputelli, J.3    Aldrich, C.E.4    Cullen, J.5    Mason, W.S.6
  • 51
    • 0022502287 scopus 로고
    • Biochemical and genetic evidence for the hepatitis B virus replication strategy
    • 3961490
    • Seeger C, Ganem D, Varmus HE, Biochemical and genetic evidence for the hepatitis B virus replication strategy. Science. 1986;232(4749):477–84. 3961490
    • (1986) Science , vol.232 , Issue.4749 , pp. 477-484
    • Seeger, C.1    Ganem, D.2    Varmus, H.E.3
  • 52
    • 0026670507 scopus 로고
    • Recognition efficiency of the hepatitis B virus polyadenylation signals is tissue specific in transgenic mice
    • 1357192
    • Perfumo S, Amicone L, Colloca S, Giorgio M, Pozzi L, Tripodi M, Recognition efficiency of the hepatitis B virus polyadenylation signals is tissue specific in transgenic mice. Journal of virology. 1992;66(11):6819–23. 1357192
    • (1992) Journal of virology , vol.66 , Issue.11 , pp. 6819-6823
    • Perfumo, S.1    Amicone, L.2    Colloca, S.3    Giorgio, M.4    Pozzi, L.5    Tripodi, M.6
  • 54
    • 33646722873 scopus 로고    scopus 로고
    • Recombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 protein
    • 16699015
    • Shapiro GS, Van Peursem C, Ornelles DA, Schaack J, DeGregori J, Recombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 protein. Journal of virology. 2006;80(11):5349–60. 16699015
    • (2006) Journal of virology , vol.80 , Issue.11 , pp. 5349-5360
    • Shapiro, G.S.1    Van Peursem, C.2    Ornelles, D.A.3    Schaack, J.4    DeGregori, J.5
  • 55
    • 0037139563 scopus 로고    scopus 로고
    • Transcriptional activation of the promoter of human cytomegalovirus immediate early gene (CMV-IE) by the hepatitis B viral X protein (HBx) through the NF-kappaB site
    • 11900849
    • Assogba BD, Choi BH, Rho HM, Transcriptional activation of the promoter of human cytomegalovirus immediate early gene (CMV-IE) by the hepatitis B viral X protein (HBx) through the NF-kappaB site. Virus research. 2002;84(1–2):171–9. 11900849
    • (2002) Virus research , vol.84 , Issue.1-2 , pp. 171-179
    • Assogba, B.D.1    Choi, B.H.2    Rho, H.M.3
  • 56
    • 0034761676 scopus 로고    scopus 로고
    • Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression
    • 11679961–
    • Qiao L, Leach K, McKinstry R, Gilfor D, Yacoub A, Park JS, et al. Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression. Hepatology. 2001;34(5):906–17. 11679961
    • (2001) Hepatology , vol.34 , Issue.5 , pp. 906-917
    • Qiao, L.1    Leach, K.2    McKinstry, R.3    Gilfor, D.4    Yacoub, A.5    Park, J.S.6
  • 57
    • 77249169899 scopus 로고    scopus 로고
    • Noncanonical Wnt11 inhibits hepatocellular carcinoma cell proliferation and migration
    • 20103596
    • Toyama T, Lee HC, Koga H, Wands JR, Kim M, Noncanonical Wnt11 inhibits hepatocellular carcinoma cell proliferation and migration. Mol Cancer Res. 2010;8(2):254–65. doi: 10.1158/1541-7786.MCR-09-023820103596
    • (2010) Mol Cancer Res , vol.8 , Issue.2 , pp. 254-265
    • Toyama, T.1    Lee, H.C.2    Koga, H.3    Wands, J.R.4    Kim, M.5
  • 58
    • 70149097778 scopus 로고    scopus 로고
    • Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2
    • 19706769–
    • Welch C, Santra MK, El-Assaad W, Zhu X, Huber WE, Keys RA, et al. Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2. Cancer research. 2009;69(17):6782–9. doi: 10.1158/0008-5472.CAN-09-012819706769
    • (2009) Cancer research , vol.69 , Issue.17 , pp. 6782-6789
    • Welch, C.1    Santra, M.K.2    El-Assaad, W.3    Zhu, X.4    Huber, W.E.5    Keys, R.A.6
  • 59
    • 84858020291 scopus 로고    scopus 로고
    • FAT SIGNALS—lipases and lipolysis in lipid metabolism and signaling
    • 22405066–
    • Zechner R, Zimmermann R, Eichmann TO, Kohlwein SD, Haemmerle G, Lass A, et al. FAT SIGNALS—lipases and lipolysis in lipid metabolism and signaling. Cell metabolism. 2012;15(3):279–91. doi: 10.1016/j.cmet.2011.12.01822405066
    • (2012) Cell metabolism , vol.15 , Issue.3 , pp. 279-291
    • Zechner, R.1    Zimmermann, R.2    Eichmann, T.O.3    Kohlwein, S.D.4    Haemmerle, G.5    Lass, A.6
  • 60
    • 84881484385 scopus 로고    scopus 로고
    • The g0/g1 switch gene 2 is an important regulator of hepatic triglyceride metabolism
    • 23951308
    • Wang Y, Zhang Y, Qian H, Lu J, Zhang Z, Min X, et al. The g0/g1 switch gene 2 is an important regulator of hepatic triglyceride metabolism. PloS one. 2013;8(8):e72315. doi: 10.1371/journal.pone.007231523951308
    • (2013) PloS one , vol.8 , Issue.8 , pp. 72315
    • Wang, Y.1    Zhang, Y.2    Qian, H.3    Lu, J.4    Zhang, Z.5    Min, X.6
  • 61
    • 84868601291 scopus 로고    scopus 로고
    • The G0/G1 switch gene 2 (G0S2): regulating metabolism and beyond
    • 23032787
    • Heckmann BL, Zhang X, Xie X, Liu J, The G0/G1 switch gene 2 (G0S2): regulating metabolism and beyond. Biochimica et biophysica acta. 2013;1831(2):276–81. doi: 10.1016/j.bbalip.2012.09.01623032787
    • (2013) Biochimica et biophysica acta , vol.1831 , Issue.2 , pp. 276-281
    • Heckmann, B.L.1    Zhang, X.2    Xie, X.3    Liu, J.4
  • 62
    • 84871048843 scopus 로고    scopus 로고
    • Adenovirus signalling in entry
    • 23083122
    • Wolfrum N, Greber UF, Adenovirus signalling in entry. Cellular microbiology. 2013;15(1):53–62. doi: 10.1111/cmi.1205323083122
    • (2013) Cellular microbiology , vol.15 , Issue.1 , pp. 53-62
    • Wolfrum, N.1    Greber, U.F.2
  • 63
    • 84964314385 scopus 로고    scopus 로고
    • Comparison of library preparation methods reveals their impact on interpretation of metatranscriptomic data
    • 25331572
    • Alberti A, Belser C, Engelen S, Bertrand L, Orvain C, Brinas L, et al. Comparison of library preparation methods reveals their impact on interpretation of metatranscriptomic data. BMC genomics. 2014;15:912. doi: 10.1186/1471-2164-15-91225331572
    • (2014) BMC genomics , vol.15 , pp. 912
    • Alberti, A.1    Belser, C.2    Engelen, S.3    Bertrand, L.4    Orvain, C.5    Brinas, L.6
  • 65
    • 84901444946 scopus 로고    scopus 로고
    • Genome-wide transcriptional sequencing identifies novel mutations in metabolic genes in human hepatocellular carcinoma
    • ..;():–
    • Meerzaman DM, Yan C, Chen QR, Edmonson MN, Schaefer CF, Clifford RJ, et al. Genome-wide transcriptional sequencing identifies novel mutations in metabolic genes in human hepatocellular carcinoma. Cancer genomics & proteomics. 2014;11(1):1–12.
    • (2014) Cancer genomics & proteomics , vol.11 , Issue.1 , pp. 1-12
    • Meerzaman, D.M.1    Yan, C.2    Chen, Q.R.3    Edmonson, M.N.4    Schaefer, C.F.5    Clifford, R.J.6
  • 66
    • 84879762339 scopus 로고    scopus 로고
    • Liver microRNA hsa-miR-125a-5p in HBV chronic infection: correlation with HBV replication and disease progression
    • 23843939
    • Coppola N, Potenza N, Pisaturo M, Mosca N, Tonziello G, Signoriello G, et al. Liver microRNA hsa-miR-125a-5p in HBV chronic infection: correlation with HBV replication and disease progression. PloS one. 2013;8(7):e65336. doi: 10.1371/journal.pone.006533623843939
    • (2013) PloS one , vol.8 , Issue.7 , pp. 65336
    • Coppola, N.1    Potenza, N.2    Pisaturo, M.3    Mosca, N.4    Tonziello, G.5    Signoriello, G.6
  • 67
    • 84862487828 scopus 로고    scopus 로고
    • TGF-beta and iron differently alter HBV replication in human hepatocytes through TGF-beta/BMP signaling and cellular microRNA expression
    • 22723983
    • Park SO, Kumar M, Gupta S, TGF-beta and iron differently alter HBV replication in human hepatocytes through TGF-beta/BMP signaling and cellular microRNA expression. PloS one. 2012;7(6):e39276. doi: 10.1371/journal.pone.003927622723983
    • (2012) PloS one , vol.7 , Issue.6 , pp. 39276
    • Park, S.O.1    Kumar, M.2    Gupta, S.3
  • 68
    • 79960236156 scopus 로고    scopus 로고
    • Human microRNA hsa-miR-125a-5p interferes with expression of hepatitis B virus surface antigen
    • 21317190, Epub 2011/02/15
    • Potenza N, Papa U, Mosca N, Zerbini F, Nobile V, Russo A, Human microRNA hsa-miR-125a-5p interferes with expression of hepatitis B virus surface antigen. Nucleic acids research. 2011;39(12):5157–63. Epub 2011/02/15. doi: 10.1093/nar/gkr06721317190
    • (2011) Nucleic acids research , vol.39 , Issue.12 , pp. 5157-5163
    • Potenza, N.1    Papa, U.2    Mosca, N.3    Zerbini, F.4    Nobile, V.5    Russo, A.6
  • 69
    • 79751484450 scopus 로고    scopus 로고
    • Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma
    • 21316602, .Epub 2011/02/15
    • Hou J, Lin L, Zhou W, Wang Z, Ding G, Dong Q, et al. Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer cell. 2011;19(2):232–43. Epub 2011/02/15. doi: 10.1016/j.ccr.2011.01.00121316602
    • (2011) Cancer cell , vol.19 , Issue.2 , pp. 232-243
    • Hou, J.1    Lin, L.2    Zhou, W.3    Wang, Z.4    Ding, G.5    Dong, Q.6
  • 70
    • 80052026310 scopus 로고    scopus 로고
    • MicroRNAs-372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B
    • 21608007, .Epub 2011/05/25
    • Guo H, Liu H, Mitchelson K, Rao H, Luo M, Xie L, et al. MicroRNAs-372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B. Hepatology. 2011;54(3):808–19. Epub 2011/05/25. doi: 10.1002/hep.2444121608007
    • (2011) Hepatology , vol.54 , Issue.3 , pp. 808-819
    • Guo, H.1    Liu, H.2    Mitchelson, K.3    Rao, H.4    Luo, M.5    Xie, L.6
  • 71
    • 84872865445 scopus 로고    scopus 로고
    • MicroRNA-501 promotes HBV replication by targeting HBXIP
    • 23266610, .Epub 2012/12/26
    • Jin J, Tang S, Xia L, Du R, Xie H, Song J, et al. MicroRNA-501 promotes HBV replication by targeting HBXIP. Biochemical and biophysical research communications. 2013;430(4):1228–33. Epub 2012/12/26. doi: 10.1016/j.bbrc.2012.12.07123266610
    • (2013) Biochemical and biophysical research communications , vol.430 , Issue.4 , pp. 1228-1233
    • Jin, J.1    Tang, S.2    Xia, L.3    Du, R.4    Xie, H.5    Song, J.6
  • 72
    • 77953574309 scopus 로고    scopus 로고
    • Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3
    • 20447714, .Epub 2010/05/08
    • Wang Y, Lu Y, Toh ST, Sung WK, Tan P, Chow P, et al. Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3. Journal of hepatology. 2010;53(1):57–66. Epub 2010/05/08. doi: 10.1016/j.jhep.2009.12.04320447714
    • (2010) Journal of hepatology , vol.53 , Issue.1 , pp. 57-66
    • Wang, Y.1    Lu, Y.2    Toh, S.T.3    Sung, W.K.4    Tan, P.5    Chow, P.6
  • 73
    • 80052102854 scopus 로고    scopus 로고
    • Hepatitis B virus and hepatocellular carcinoma at the miRNA level. World journal of gastroenterology
    • 21876625, .:Epub 2011/08/31
    • Zhang ZZ, Liu X, Wang DQ, Teng MK, Niu LW, Huang AL, et al. Hepatitis B virus and hepatocellular carcinoma at the miRNA level. World journal of gastroenterology: WJG. 2011;17(28):3353–8. Epub 2011/08/31. doi: 10.3748/wjg.v17.i28.335321876625
    • (2011) WJG , vol.17 , Issue.28 , pp. 3353-3358
    • Zhang, Z.Z.1    Liu, X.2    Wang, D.Q.3    Teng, M.K.4    Niu, L.W.5    Huang, A.L.6
  • 74
    • 84887009429 scopus 로고    scopus 로고
    • microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture
    • 24314655
    • Xu G, Gao Z, He W, Ma Y, Feng X, Cai T, et al. microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture. Virology. 2014;448:247–54. doi: 10.1016/j.virol.2013.10.01624314655
    • (2014) Virology , vol.448 , pp. 247-254
    • Xu, G.1    Gao, Z.2    He, W.3    Ma, Y.4    Feng, X.5    Cai, T.6
  • 75
    • 60649100708 scopus 로고    scopus 로고
    • Altered expression profiles of microRNAs in a stable hepatitis B virus-expressing cell line
    • 19187610, .Epub 2009/02/04
    • Liu Y, Zhao JJ, Wang CM, Li MY, Han P, Wang L, et al. Altered expression profiles of microRNAs in a stable hepatitis B virus-expressing cell line. Chinese medical journal. 2009;122(1):10–4. Epub 2009/02/04. 19187610
    • (2009) Chinese medical journal , vol.122 , Issue.1 , pp. 10-14
    • Liu, Y.1    Zhao, J.J.2    Wang, C.M.3    Li, M.Y.4    Han, P.5    Wang, L.6
  • 76
    • 79955109306 scopus 로고    scopus 로고
    • Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1
    • 21520166, .Epub 2011/04/27
    • Zhang X, Zhang E, Ma Z, Pei R, Jiang M, Schlaak JF, et al. Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1. Hepatology. 2011;53(5):1476–85. Epub 2011/04/27. doi: 10.1002/hep.2419521520166
    • (2011) Hepatology , vol.53 , Issue.5 , pp. 1476-1485
    • Zhang, X.1    Zhang, E.2    Ma, Z.3    Pei, R.4    Jiang, M.5    Schlaak, J.F.6
  • 77
    • 0031608392 scopus 로고    scopus 로고
    • Maintained function of primary human hepatocytes by cellular interactions in coculture: implications for liver support systems
    • 9665034
    • Auth MK, Okamoto M, Ishida Y, Keogh A, Auth SH, Gerlach J, et al. Maintained function of primary human hepatocytes by cellular interactions in coculture: implications for liver support systems. Transpl Int. 1998;11Suppl 1:S439–43. 9665034
    • (1998) Transpl Int , vol.11 , pp. 439-443
    • Auth, M.K.1    Okamoto, M.2    Ishida, Y.3    Keogh, A.4    Auth, S.H.5    Gerlach, J.6
  • 78
    • 0029973363 scopus 로고    scopus 로고
    • Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1
    • 8626707
    • Loyer P, Cariou S, Glaise D, Bilodeau M, Baffet G, Guguen-Guillouzo C, Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1. The Journal of biological chemistry. 1996;271(19):11484–92. 8626707
    • (1996) The Journal of biological chemistry , vol.271 , Issue.19 , pp. 11484-11492
    • Loyer, P.1    Cariou, S.2    Glaise, D.3    Bilodeau, M.4    Baffet, G.5    Guguen-Guillouzo, C.6
  • 79
    • 0030894449 scopus 로고    scopus 로고
    • Liver regeneration
    • 9082986
    • Michalopoulos GK, DeFrances MC, Liver regeneration. Science. 1997;276(5309):60–6. 9082986
    • (1997) Science , vol.276 , Issue.5309 , pp. 60-66
    • Michalopoulos, G.K.1    DeFrances, M.C.2
  • 80
    • 0042904900 scopus 로고    scopus 로고
    • Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties
    • 12867492
    • Wilkening S, Stahl F, Bader A, Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties. Drug Metab Dispos. 2003;31(8):1035–42. 12867492
    • (2003) Drug Metab Dispos , vol.31 , Issue.8 , pp. 1035-1042
    • Wilkening, S.1    Stahl, F.2    Bader, A.3
  • 81
    • 34247117935 scopus 로고    scopus 로고
    • Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection
    • 17287266–
    • Boni C, Fisicaro P, Valdatta C, Amadei B, Di Vincenzo P, Giuberti T, et al. Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection. Journal of virology. 2007;81(8):4215–25. 17287266
    • (2007) Journal of virology , vol.81 , Issue.8 , pp. 4215-4225
    • Boni, C.1    Fisicaro, P.2    Valdatta, C.3    Amadei, B.4    Di Vincenzo, P.5    Giuberti, T.6
  • 82
    • 79960872707 scopus 로고    scopus 로고
    • Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily
    • 21787333
    • Bingle CD, Seal RL, Craven CJ, Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Biochem Soc Trans. 2011;39(4):977–83. doi: 10.1042/BST039097721787333
    • (2011) Biochem Soc Trans , vol.39 , Issue.4 , pp. 977-983
    • Bingle, C.D.1    Seal, R.L.2    Craven, C.J.3
  • 83
    • 79960858267 scopus 로고    scopus 로고
    • Distant cousins: genomic and sequence diversity within the BPI fold-containing (BPIF)/PLUNC protein family
    • 21787330
    • Bingle CD, Bingle L, Craven CJ, Distant cousins: genomic and sequence diversity within the BPI fold-containing (BPIF)/PLUNC protein family. Biochem Soc Trans. 2011;39(4):961–5. doi: 10.1042/BST039096121787330
    • (2011) Biochem Soc Trans , vol.39 , Issue.4 , pp. 961-965
    • Bingle, C.D.1    Bingle, L.2    Craven, C.J.3
  • 84
    • 58349122284 scopus 로고    scopus 로고
    • Hepatitis B virus infection is dependent on cholesterol in the viral envelope
    • 19016777
    • Bremer CM, Bung C, Kott N, Hardt M, Glebe D, Hepatitis B virus infection is dependent on cholesterol in the viral envelope. Cellular microbiology. 2009;11(2):249–60. doi: 10.1111/j.1462-5822.2008.01250.x19016777
    • (2009) Cellular microbiology , vol.11 , Issue.2 , pp. 249-260
    • Bremer, C.M.1    Bung, C.2    Kott, N.3    Hardt, M.4    Glebe, D.5
  • 85
    • 84855826018 scopus 로고    scopus 로고
    • Cholesterol depletion of hepatoma cells impairs hepatitis B virus envelopment by altering the topology of the large envelope protein
    • 21994451
    • Dorobantu C, Macovei A, Lazar C, Dwek RA, Zitzmann N, Branza-Nichita N, Cholesterol depletion of hepatoma cells impairs hepatitis B virus envelopment by altering the topology of the large envelope protein. Journal of virology. 2011;85(24):13373–83. doi: 10.1128/JVI.05423-1121994451
    • (2011) Journal of virology , vol.85 , Issue.24 , pp. 13373-13383
    • Dorobantu, C.1    Macovei, A.2    Lazar, C.3    Dwek, R.A.4    Zitzmann, N.5    Branza-Nichita, N.6
  • 87
    • 77950609088 scopus 로고    scopus 로고
    • Expression of pituitary tumor-transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)-associated liver diseases: evidence for an HBV X protein-mediated inhibition of PTTG1 ubiquitination and degradation
    • 20198633–
    • Molina-Jimenez F, Benedicto I, Murata M, Martin-Vilchez S, Seki T, Antonio Pintor-Toro J, et al. Expression of pituitary tumor-transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)-associated liver diseases: evidence for an HBV X protein-mediated inhibition of PTTG1 ubiquitination and degradation. Hepatology. 2010;51(3):777–87. doi: 10.1002/hep.2346820198633
    • (2010) Hepatology , vol.51 , Issue.3 , pp. 777-787
    • Molina-Jimenez, F.1    Benedicto, I.2    Murata, M.3    Martin-Vilchez, S.4    Seki, T.5    Antonio Pintor-Toro, J.6
  • 88
    • 44649166448 scopus 로고    scopus 로고
    • Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B
    • 18455515–, 49 e1-3
    • Zhang Z, Zhang JY, Wherry EJ, Jin B, Xu B, Zou ZS, et al. Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B. Gastroenterology. 2008;134(7):1938–49, 49 e1-3. doi: 10.1053/j.gastro.2008.03.03718455515
    • (2008) Gastroenterology , vol.134 , Issue.7 , pp. 1938-1949
    • Zhang, Z.1    Zhang, J.Y.2    Wherry, E.J.3    Jin, B.4    Xu, B.5    Zou, Z.S.6
  • 89
    • 84924347993 scopus 로고    scopus 로고
    • Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens
    • 25745177
    • Jovanovic M, Rooney MS, Mertins P, Przybylski D, Chevrier N, Satija R, et al. Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens. Science. 2015;347(6226):1259038. doi: 10.1126/science.125903825745177
    • (2015) Science , vol.347 , Issue.6226 , pp. 1259038
    • Jovanovic, M.1    Rooney, M.S.2    Mertins, P.3    Przybylski, D.4    Chevrier, N.5    Satija, R.6
  • 93
    • 47049100688 scopus 로고    scopus 로고
    • Hepatitis B virus HBx protein localizes to mitochondria in primary rat hepatocytes and modulates mitochondrial membrane potential
    • 18448529, Epub 2008/05/02
    • Clippinger AJ, Bouchard MJ, Hepatitis B virus HBx protein localizes to mitochondria in primary rat hepatocytes and modulates mitochondrial membrane potential. Journal of virology. 2008;82(14):6798–811. Epub 2008/05/02. doi: 10.1128/JVI.00154-0818448529
    • (2008) Journal of virology , vol.82 , Issue.14 , pp. 6798-6811
    • Clippinger, A.J.1    Bouchard, M.J.2
  • 94
    • 0001471696 scopus 로고    scopus 로고
    • Isolation of hepatocytes by collagenase perfusion
    • .. p.–
    • Seglen P, Isolation of hepatocytes by collagenase perfusion. Methods in Toxicology. 11993. p. 231–43.
    • Methods in Toxicology , vol.11993 , pp. 231-243
    • Seglen, P.1
  • 95
    • 0035861455 scopus 로고    scopus 로고
    • Calcium signaling by HBx protein in hepatitis B virus DNA replication
    • 11743208
    • Bouchard MJ, Wang LH, Schneider RJ, Calcium signaling by HBx protein in hepatitis B virus DNA replication. Science. 2001;294(5550):2376–8. 11743208
    • (2001) Science , vol.294 , Issue.5550 , pp. 2376-2378
    • Bouchard, M.J.1    Wang, L.H.2    Schneider, R.J.3
  • 97
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • 19451168
    • Li H, Durbin R, Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics. 2009;25(14):1754–60. doi: 10.1093/bioinformatics/btp32419451168
    • (2009) Bioinformatics , vol.25 , Issue.14 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 99
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • 23618408
    • Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL, TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome biology. 2013;14(4):R36. doi: 10.1186/gb-2013-14-4-r3623618408
    • (2013) Genome biology , vol.14 , Issue.4 , pp. 36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 100
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • 22388286
    • Langmead B, Salzberg SL, Fast gapped-read alignment with Bowtie 2. Nature methods. 2012;9(4):357–9. doi: 10.1038/nmeth.192322388286
    • (2012) Nature methods , vol.9 , Issue.4 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 102
    • 84959528353 scopus 로고    scopus 로고
    • .;
    • Team RCR: A language and environment for statistical computing. R Foundation for Statistical Computing; 2014.
    • (2014)
  • 103
    • 84959565453 scopus 로고    scopus 로고
    • Morgan M, Pages H, Obenchain V, Hayden N. Rsamtools: Binary alignment (BAM), FASTA, variant call (BCF), and tabix file import
    • Morgan M, Pages H, Obenchain V, Hayden N. Rsamtools: Binary alignment (BAM), FASTA, variant call (BCF), and tabix file import.
  • 105
    • 46249106990 scopus 로고    scopus 로고
    • Mapping and quantifying mammalian transcriptomes by RNA-Seq
    • 18516045
    • Mortazavi A, Williams BA, McCue K, Schaeffer L, Wold B, Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nature methods. 2008;5(7):621–8. doi: 10.1038/nmeth.122618516045
    • (2008) Nature methods , vol.5 , Issue.7 , pp. 621-628
    • Mortazavi, A.1    Williams, B.A.2    McCue, K.3    Schaeffer, L.4    Wold, B.5
  • 106
    • 84859885816 scopus 로고    scopus 로고
    • Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
    • 22383036–
    • Trapnell C, Roberts A, Goff L, Pertea G, Kim D, Kelley DR, et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nature protocols. 2012;7(3):562–78. doi: 10.1038/nprot.2012.01622383036
    • (2012) Nature protocols , vol.7 , Issue.3 , pp. 562-578
    • Trapnell, C.1    Roberts, A.2    Goff, L.3    Pertea, G.4    Kim, D.5    Kelley, D.R.6
  • 107
    • 84924629414 scopus 로고    scopus 로고
    • Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
    • 25516281
    • Love MI, Huber W, Anders S, Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome biology. 2014;15(12):550. 25516281
    • (2014) Genome biology , vol.15 , Issue.12 , pp. 550
    • Love, M.I.1    Huber, W.2    Anders, S.3
  • 108
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • 20979621
    • Anders S, Huber W, Differential expression analysis for sequence count data. Genome biology. 2010;11(10):R106. doi: 10.1186/gb-2010-11-10-r10620979621
    • (2010) Genome biology , vol.11 , Issue.10 , pp. 106
    • Anders, S.1    Huber, W.2
  • 109
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
    • 19910308
    • Robinson MD, McCarthy DJ, Smyth GK, edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010;26(1):139–40. doi: 10.1093/bioinformatics/btp61619910308
    • (2010) Bioinformatics , vol.26 , Issue.1 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 110
    • 0001677717 scopus 로고
    • Controlling the False Discovery Rate—a Practical and Powerful Approach to Multiple Testing
    • .;():–
    • Benjamini Y, Hochberg Y, Controlling the False Discovery Rate—a Practical and Powerful Approach to Multiple Testing. J Roy Stat Soc B Met. 1995;57(1):289–300.
    • (1995) J Roy Stat Soc B Met , vol.57 , Issue.1 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 112
    • 84959542608 scopus 로고    scopus 로고
    • :;
    • Wickham H, ggplot2: elegant graphics for data analysis: SpringerNew York; 2009.
    • (2009)
    • Wickham, H.1
  • 113
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: a flexible suite of utilities for comparing genomic features
    • 20110278
    • Quinlan AR, Hall IM, BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics. 2010;26(6):841–2. doi: 10.1093/bioinformatics/btq03320110278
    • (2010) Bioinformatics , vol.26 , Issue.6 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 114
    • 84858314394 scopus 로고    scopus 로고
    • BioMart: driving a paradigm change in biological data management
    • Kasprzyk A, BioMart: driving a paradigm change in biological data management. Database (Oxford). 2011;2011:bar049.
    • (2011) Database (Oxford) , vol.2011 , pp. 49
    • Kasprzyk, A.1
  • 115
    • 84886415892 scopus 로고    scopus 로고
    • Assessing co-regulation of directly linked genes in biological networks using microarray time series analysis
    • 23876997
    • Del Sorbo MR, Balzano W, Donato M, Draghici S, Assessing co-regulation of directly linked genes in biological networks using microarray time series analysis. Biosystems. 2013;114(2):149–54. doi: 10.1016/j.biosystems.2013.07.00623876997
    • (2013) Biosystems , vol.114 , Issue.2 , pp. 149-154
    • Del Sorbo, M.R.1    Balzano, W.2    Donato, M.3    Draghici, S.4


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