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Volumn 8, Issue 8, 2013, Pages

The G0/G1 Switch Gene 2 Is an Important Regulator of Hepatic Triglyceride Metabolism

Author keywords

[No Author keywords available]

Indexed keywords

6 [N (7 NITROBENZ 2 OXA 1 3 DIAZOL 4 YL)AMINO] 6 DEOXYGLUCOSE; ADENOVIRUS VECTOR; CARBOHYDRATE DERIVATIVE; CHOLESTEROL; FAT DROPLET; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; KETONE BODY; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84881484385     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072315     Document Type: Article
Times cited : (50)

References (38)
  • 1
    • 79956338241 scopus 로고    scopus 로고
    • Insulin signaling to hepatic lipid metabolism in health and disease
    • 10.3109/10409238.2011.562481
    • Leavens KF, Birnbaum MJ, (2011) Insulin signaling to hepatic lipid metabolism in health and disease. Crit Rev Biochem Mol Biol 46: 200-215. doi:10.3109/10409238.2011.562481. PubMed: 21599535.
    • (2011) Crit Rev Biochem Mol Biol , vol.46 , pp. 200-215
    • Leavens, K.F.1    Birnbaum, M.J.2
  • 2
    • 79953246834 scopus 로고    scopus 로고
    • Hepatic steatosis and Type 2 diabetes: current and future treatment considerations
    • 10.1586/erc.11.15
    • Richard J, Lingvay I, (2011) Hepatic steatosis and Type 2 diabetes: current and future treatment considerations. Expert Rev Cardiovasc Ther 9: 321-328. doi:10.1586/erc.11.15. PubMed: 21438811.
    • (2011) Expert Rev Cardiovasc Ther , vol.9 , pp. 321-328
    • Richard, J.1    Lingvay, I.2
  • 3
    • 3543029821 scopus 로고    scopus 로고
    • Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease
    • 10.1074/jbc.M313478200
    • Samuel VT, Liu ZX, Qu X, Elder BD, Bilz S, et al. (2004) Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. J Biol Chem 279: 32345-32353. doi:10.1074/jbc.M313478200. PubMed: 15166226.
    • (2004) J Biol Chem , vol.279 , pp. 32345-32353
    • Samuel, V.T.1    Liu, Z.X.2    Qu, X.3    Elder, B.D.4    Bilz, S.5
  • 4
    • 34848844300 scopus 로고    scopus 로고
    • Hepatic steatosis is associated with a greater prevalence of coronary artery calcification in asymptomatic men
    • 10.1016/j.atherosclerosis.2007.01.026
    • Santos RD, Nasir K, Conceição RD, Sarwar A, Carvalho JA, et al. (2007) Hepatic steatosis is associated with a greater prevalence of coronary artery calcification in asymptomatic men. Atherosclerosis 194: 517-519. doi:10.1016/j.atherosclerosis.2007.01.026. PubMed: 17335826.
    • (2007) Atherosclerosis , vol.194 , pp. 517-519
    • Santos, R.D.1    Nasir, K.2    Conceição, R.D.3    Sarwar, A.4    Carvalho, J.A.5
  • 5
    • 79953755370 scopus 로고    scopus 로고
    • AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice
    • 10.1016/j.cmet.2011.03.009
    • Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, et al. (2011) AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice. Cell Metab 13: 376-388. doi:10.1016/j.cmet.2011.03.009. PubMed: 21459323.
    • (2011) Cell Metab , vol.13 , pp. 376-388
    • Li, Y.1    Xu, S.2    Mihaylova, M.M.3    Zheng, B.4    Hou, X.5
  • 6
    • 4644305245 scopus 로고    scopus 로고
    • Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: role of visceral fat accumulation
    • 10.2337/diacare.27.10.2498
    • Targher G, Bertolini L, Padovani R, Zenari L, Zoppini G, et al. (2004) Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: role of visceral fat accumulation. Diabetes Care 27: 2498-2500. doi:10.2337/diacare.27.10.2498. PubMed: 15451925.
    • (2004) Diabetes Care , vol.27 , pp. 2498-2500
    • Targher, G.1    Bertolini, L.2    Padovani, R.3    Zenari, L.4    Zoppini, G.5
  • 7
    • 84856385743 scopus 로고    scopus 로고
    • Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver
    • 10.1002/hep.24685
    • Marmugi A, Ducheix S, Lasserre F, Polizzi A, Paris A, et al. (2012) Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver. Hepatology 55: 395-407. doi:10.1002/hep.24685. PubMed: 21932408.
    • (2012) Hepatology , vol.55 , pp. 395-407
    • Marmugi, A.1    Ducheix, S.2    Lasserre, F.3    Polizzi, A.4    Paris, A.5
  • 8
    • 78751496304 scopus 로고    scopus 로고
    • Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning
    • 10.1002/hep.24006
    • Ong KT, Mashek MT, Bu SY, Greenberg AS, Mashek DG, (2011) Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning. Hepatology 53: 116-126. doi:10.1002/hep.24006. PubMed: 20967758.
    • (2011) Hepatology , vol.53 , pp. 116-126
    • Ong, K.T.1    Mashek, M.T.2    Bu, S.Y.3    Greenberg, A.S.4    Mashek, D.G.5
  • 9
    • 33747047885 scopus 로고    scopus 로고
    • Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action
    • 10.2337/db05-0705
    • Samuel VT, Choi CS, Phillips TG, Romanelli AJ, Geisler JG, et al. (2006) Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action. Diabetes 55: 2042-2050. doi:10.2337/db05-0705. PubMed: 16804074.
    • (2006) Diabetes , vol.55 , pp. 2042-2050
    • Samuel, V.T.1    Choi, C.S.2    Phillips, T.G.3    Romanelli, A.J.4    Geisler, J.G.5
  • 10
    • 33750912016 scopus 로고    scopus 로고
    • Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients
    • 10.1093/dnares/dsl006
    • Nakamura N, Shimaoka Y, Tougan T, Onda H, Okuzaki D, et al. (2006) Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients. DNA Res 13: 169-183. doi:10.1093/dnares/dsl006. PubMed: 17082220.
    • (2006) DNA Res , vol.13 , pp. 169-183
    • Nakamura, N.1    Shimaoka, Y.2    Tougan, T.3    Onda, H.4    Okuzaki, D.5
  • 11
    • 0026094018 scopus 로고
    • A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated
    • 10.1089/dna.1991.10.581
    • Russell L, Forsdyke DR, (1991) A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated. DNA Cell Biol 10: 581-591. doi:10.1089/dna.1991.10.581. PubMed: 1930693.
    • (1991) DNA Cell Biol , vol.10 , pp. 581-591
    • Russell, L.1    Forsdyke, D.R.2
  • 12
    • 29144451332 scopus 로고    scopus 로고
    • The G0/G1 switch gene 2 is a novel PPAR target gene
    • 10.1042/BJ20050636
    • Zandbergen F, Mandard S, Escher P, Tan NS, Patsouris D, et al. (2005) The G0/G1 switch gene 2 is a novel PPAR target gene. Biochem J 392: 313-324. doi:10.1042/BJ20050636. PubMed: 16086669.
    • (2005) Biochem J , vol.392 , pp. 313-324
    • Zandbergen, F.1    Mandard, S.2    Escher, P.3    Tan, N.S.4    Patsouris, D.5
  • 13
    • 34447550270 scopus 로고    scopus 로고
    • Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts
    • 10.1016/j.cardiores.2007.04.026
    • Teunissen BE, Smeets PJ, Willemsen PH, De Windt LJ, Van der Vusse GJ, et al. (2007) Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts. Cardiovasc Res 75: 519-529. doi:10.1016/j.cardiores.2007.04.026. PubMed: 17543901.
    • (2007) Cardiovasc Res , vol.75 , pp. 519-529
    • Teunissen, B.E.1    Smeets, P.J.2    Willemsen, P.H.3    De Windt, L.J.4    van der Vusse, G.J.5
  • 14
    • 79953689271 scopus 로고    scopus 로고
    • Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms
    • 10.1530/JME-10-0064
    • Cheng YH, Utsunomiya H, Pavone ME, Yin P, Bulun SE, (2011) Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms. J Mol Endocrinol 46: 139-153. doi:10.1530/JME-10-0064. PubMed: 21310893.
    • (2011) J Mol Endocrinol , vol.46 , pp. 139-153
    • Cheng, Y.H.1    Utsunomiya, H.2    Pavone, M.E.3    Yin, P.4    Bulun, S.E.5
  • 16
    • 77249118270 scopus 로고    scopus 로고
    • The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase
    • 10.1016/j.cmet.2010.02.003
    • Yang X, Lu X, Lombès M, Rha GB, Chi YI, et al. (2010) The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. Cell Metab 11: 194-205. doi:10.1016/j.cmet.2010.02.003. PubMed: 20197052.
    • (2010) Cell Metab , vol.11 , pp. 194-205
    • Yang, X.1    Lu, X.2    Lombès, M.3    Rha, G.B.4    Chi, Y.I.5
  • 17
    • 0031760438 scopus 로고    scopus 로고
    • Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2)
    • 10.1002/(SICI)1097-0177(199812)213:4
    • Bächner D, Ahrens M, Schröder D, Hoffmann A, Lauber J, et al. (1998) Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev Dyn 213: 398-411. doi:10.1002/(SICI)1097-0177(199812)213:4. PubMed: 9853961.
    • (1998) Dev Dyn , vol.213 , pp. 398-411
    • Bächner, D.1    Ahrens, M.2    Schröder, D.3    Hoffmann, A.4    Lauber, J.5
  • 18
    • 0344010662 scopus 로고    scopus 로고
    • CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma
    • 10.1038/nature02110
    • Herzig S, Hedrick S, Morantte I, Koo SH, Galimi F, et al. (2003) CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature 426: 190-193. doi:10.1038/nature02110. PubMed: 14614508.
    • (2003) Nature , vol.426 , pp. 190-193
    • Herzig, S.1    Hedrick, S.2    Morantte, I.3    Koo, S.H.4    Galimi, F.5
  • 19
    • 0034571515 scopus 로고    scopus 로고
    • Relationship between signal transduction and PPAR alpha-regulated genes of lipid metabolism in rat hepatic-derived Fao cells
    • 10.1385/CBB:32:1-3:213
    • Latruffe N, Passilly P, Jannin B, Motojima K, Cherkaoui Malki M, et al. (2000) Relationship between signal transduction and PPAR alpha-regulated genes of lipid metabolism in rat hepatic-derived Fao cells. Cell Biochem Biophys 32: 213-220. doi:10.1385/CBB:32:1-3:213. PubMed: 11330049.
    • (2000) Cell Biochem Biophys , vol.32 , pp. 213-220
    • Latruffe, N.1    Passilly, P.2    Jannin, B.3    Motojima, K.4    Cherkaoui Malki, M.5
  • 20
    • 33244494398 scopus 로고    scopus 로고
    • PPARalpha activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes
    • 16282640
    • Edvardsson U, Ljungberg A, Lindén D, William-Olsson L, Peilot-Sjögren H, et al. (2006) PPARalpha activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes. J Lipid Res 47: 329-340. PubMed: 16282640.
    • (2006) J Lipid Res , vol.47 , pp. 329-340
    • Edvardsson, U.1    Ljungberg, A.2    Lindén, D.3    William-Olsson, L.4    Peilot-Sjögren, H.5
  • 21
    • 0036260018 scopus 로고    scopus 로고
    • Differential effects of fenofibrate or simvastatin treatment of rats on hepatic microsomal overt and latent diacylglycerol acyltransferase activities
    • 10.2337/diabetes.51.6.1708
    • Waterman IJ, Zammit VA, (2002) Differential effects of fenofibrate or simvastatin treatment of rats on hepatic microsomal overt and latent diacylglycerol acyltransferase activities. Diabetes 51: 1708-1713. doi:10.2337/diabetes.51.6.1708. PubMed: 12031956.
    • (2002) Diabetes , vol.51 , pp. 1708-1713
    • Waterman, I.J.1    Zammit, V.A.2
  • 22
    • 0036847135 scopus 로고    scopus 로고
    • AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats
    • 10.1194/jlr.M200127-JLR200
    • Ljung B, Bamberg K, Dahllöf B, Kjellstedt A, Oakes ND, et al. (2002) AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats. J Lipid Res 43: 1855-1863. doi:10.1194/jlr.M200127-JLR200. PubMed: 12401884.
    • (2002) J Lipid Res , vol.43 , pp. 1855-1863
    • Ljung, B.1    Bamberg, K.2    Dahllöf, B.3    Kjellstedt, A.4    Oakes, N.D.5
  • 23
    • 0037025390 scopus 로고    scopus 로고
    • WY14,643, a peroxisome proliferator-activated receptor alpha (PPARalpha) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatrophic A-ZIP/F-1 mice
    • 10.1074/jbc.M202449200
    • Chou CJ, Haluzik M, Gregory C, Dietz KR, Vinson C, et al. (2002) WY14,643, a peroxisome proliferator-activated receptor alpha (PPARalpha) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatrophic A-ZIP/F-1 mice. J Biol Chem 277: 24484-24489. doi:10.1074/jbc.M202449200. PubMed: 11994294.
    • (2002) J Biol Chem , vol.277 , pp. 24484-24489
    • Chou, C.J.1    Haluzik, M.2    Gregory, C.3    Dietz, K.R.4    Vinson, C.5
  • 24
    • 70350062074 scopus 로고    scopus 로고
    • Atorvastatin and fenofibrate increase apolipoprotein AV and decrease triglycerides by up-regulating peroxisome proliferator-activated receptor-alpha
    • 10.1111/j.1476-5381.2009.00350.x
    • Huang XS, Zhao SP, Bai L, Hu M, Zhao W, et al. (2009) Atorvastatin and fenofibrate increase apolipoprotein AV and decrease triglycerides by up-regulating peroxisome proliferator-activated receptor-alpha. Br J Pharmacol 158: 706-712. doi:10.1111/j.1476-5381.2009.00350.x. PubMed: 19694729.
    • (2009) Br J Pharmacol , vol.158 , pp. 706-712
    • Huang, X.S.1    Zhao, S.P.2    Bai, L.3    Hu, M.4    Zhao, W.5
  • 25
    • 33750471637 scopus 로고    scopus 로고
    • Bifendate treatment attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice
    • 10.1016/j.ejphar.2006.09.011
    • Pan SY, Yang R, Dong H, Yu ZL, Ko KM, (2006) Bifendate treatment attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Eur J Pharmacol 552: 170-175. doi:10.1016/j.ejphar.2006.09.011. PubMed: 17046746.
    • (2006) Eur J Pharmacol , vol.552 , pp. 170-175
    • Pan, S.Y.1    Yang, R.2    Dong, H.3    Yu, Z.L.4    Ko, K.M.5
  • 26
    • 62149094721 scopus 로고    scopus 로고
    • Fenofibrate ameliorates diabetic and dyslipidemic profiles in KKAy mice partly via down-regulation of 11beta-HSD1, PEPCK and DGAT2. Comparison of PPARalpha, PPARgamma, and liver x receptor agonists
    • 10.1016/j.ejphar.2009.02.024
    • Srivastava RA, (2009) Fenofibrate ameliorates diabetic and dyslipidemic profiles in KKAy mice partly via down-regulation of 11beta-HSD1, PEPCK and DGAT2. Comparison of PPARalpha, PPARgamma, and liver x receptor agonists. Eur J Pharmacol 607: 258-263. doi:10.1016/j.ejphar.2009.02.024. PubMed: 19245804.
    • (2009) Eur J Pharmacol , vol.607 , pp. 258-263
    • Srivastava, R.A.1
  • 27
    • 80052454265 scopus 로고    scopus 로고
    • ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1
    • 10.1038/nm.2439
    • Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, et al. (2011) ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1. Nat Med 17: 1076-1085. doi:10.1038/nm.2439. PubMed: 21857651.
    • (2011) Nat Med , vol.17 , pp. 1076-1085
    • Haemmerle, G.1    Moustafa, T.2    Woelkart, G.3    Büttner, S.4    Schmidt, A.5
  • 28
    • 84871901684 scopus 로고    scopus 로고
    • Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation
    • 22993196
    • Ong KT, Mashek MT, Bu SY, Mashek DG, (2012) Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation. FASEB J 27: 313-321. PubMed: 22993196.
    • (2012) FASEB J , vol.27 , pp. 313-321
    • Ong, K.T.1    Mashek, M.T.2    Bu, S.Y.3    Mashek, D.G.4
  • 29
    • 77956865739 scopus 로고    scopus 로고
    • Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2
    • 10.4161/cc.9.14.12181
    • Lu X, Yang X, Liu J, (2010) Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2. Cell Cycle 9: 2719-2725. doi:10.4161/cc.9.14.12181. PubMed: 20676045.
    • (2010) Cell Cycle , vol.9 , pp. 2719-2725
    • Lu, X.1    Yang, X.2    Liu, J.3
  • 30
    • 79959517565 scopus 로고    scopus 로고
    • Human fatty liver disease: old questions and new insights
    • 10.1126/science.1204265
    • Cohen JC, Horton JD, Hobbs HH, (2011) Human fatty liver disease: old questions and new insights. Science 332: 1519-1523. doi:10.1126/science.1204265. PubMed: 21700865.
    • (2011) Science , vol.332 , pp. 1519-1523
    • Cohen, J.C.1    Horton, J.D.2    Hobbs, H.H.3
  • 31
    • 33749407193 scopus 로고    scopus 로고
    • ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver
    • 10.1074/jbc.M601576200
    • Ma L, Robinson LN, Towle HC, (2006) ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver. J Biol Chem 281: 28721-28730. doi:10.1074/jbc.M601576200. PubMed: 16885160.
    • (2006) J Biol Chem , vol.281 , pp. 28721-28730
    • Ma, L.1    Robinson, L.N.2    Towle, H.C.3
  • 32
    • 10744228468 scopus 로고    scopus 로고
    • Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement
    • 10.2337/diabetes.52.12.2905
    • Ono H, Shimano H, Katagiri H, Yahagi N, Sakoda H, et al. (2003) Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement. Diabetes 52: 2905-2913. doi:10.2337/diabetes.52.12.2905. PubMed: 14633850.
    • (2003) Diabetes , vol.52 , pp. 2905-2913
    • Ono, H.1    Shimano, H.2    Katagiri, H.3    Yahagi, N.4    Sakoda, H.5
  • 33
    • 20944447890 scopus 로고    scopus 로고
    • Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
    • 10.1073/pnas.0408452102
    • Xu A, Lam MC, Chan KW, Wang Y, Zhang J, et al. (2005) Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci U S A 102: 6086-6091. doi:10.1073/pnas.0408452102. PubMed: 15837923.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 6086-6091
    • Xu, A.1    Lam, M.C.2    Chan, K.W.3    Wang, Y.4    Zhang, J.5
  • 34
    • 10744222107 scopus 로고    scopus 로고
    • Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity
    • 10.1073/pnas.0308617100
    • Stiles B, Wang Y, Stahl A, Bassilian S, Lee WP, et al. (2004) Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity. Proc Natl Acad Sci U S A 101: 2082-2087. doi:10.1073/pnas.0308617100. PubMed: 14769918.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2082-2087
    • Stiles, B.1    Wang, Y.2    Stahl, A.3    Bassilian, S.4    Lee, W.P.5
  • 35
    • 78650851786 scopus 로고    scopus 로고
    • Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation
    • 10.1210/en.2010-0661
    • Hoy AJ, Bruce CR, Turpin SM, Morris AJ, Febbraio MA, et al. (2011) Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation. Endocrinology 152: 48-58. doi:10.1210/en.2010-0661. PubMed: 21106876.
    • (2011) Endocrinology , vol.152 , pp. 48-58
    • Hoy, A.J.1    Bruce, C.R.2    Turpin, S.M.3    Morris, A.J.4    Febbraio, M.A.5
  • 36
    • 33646462136 scopus 로고    scopus 로고
    • Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
    • 10.1126/science.1123965
    • Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, et al. (2006) Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312: 734-737. doi:10.1126/science.1123965. PubMed: 16675698.
    • (2006) Science , vol.312 , pp. 734-737
    • Haemmerle, G.1    Lass, A.2    Zimmermann, R.3    Gorkiewicz, G.4    Meyer, C.5
  • 37
    • 79959387473 scopus 로고    scopus 로고
    • Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans
    • 10.2337/db10-1364
    • Badin PM, Louche K, Mairal A, Liebisch G, Schmitz G, et al. (2011) Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans. Diabetes 60: 1734-1742. doi:10.2337/db10-1364. PubMed: 21498783.
    • (2011) Diabetes , vol.60 , pp. 1734-1742
    • Badin, P.M.1    Louche, K.2    Mairal, A.3    Liebisch, G.4    Schmitz, G.5
  • 38
    • 80053627289 scopus 로고    scopus 로고
    • Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
    • 10.1073/pnas.1113359108
    • Kumashiro N, Erion DM, Zhang D, Kahn M, Beddow SA, et al. (2011) Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease. Proc Natl Acad Sci U S A 108: 16381-16385. doi:10.1073/pnas.1113359108. PubMed: 21930939.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 16381-16385
    • Kumashiro, N.1    Erion, D.M.2    Zhang, D.3    Kahn, M.4    Beddow, S.A.5


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