-
1
-
-
84893767674
-
DNA assembly of nanoparticle superstructures for controlled biological delivery and elimination
-
Chou LYT, Zagorovsky K, Chan WCW (2014) DNA assembly of nanoparticle superstructures for controlled biological delivery and elimination. Nat Nanotechnol 9(2):148-155.
-
(2014)
Nat Nanotechnol
, vol.9
, Issue.2
, pp. 148-155
-
-
Chou, L.Y.T.1
Zagorovsky, K.2
Chan, W.C.W.3
-
2
-
-
77955488728
-
In vivo near-infrared fluorescence imaging of cancer with nanoparticle-based probes
-
He X, Wang K, Cheng Z (2010) In vivo near-infrared fluorescence imaging of cancer with nanoparticle-based probes. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2(4):349-366.
-
(2010)
Wiley Interdiscip Rev Nanomed Nanobiotechnol
, vol.2
, Issue.4
, pp. 349-366
-
-
He, X.1
Wang, K.2
Cheng, Z.3
-
3
-
-
77951261362
-
Tumor targeting chitosan nanoparticles for dual-modality optical/MR cancer imaging
-
Nam T, et al. (2010) Tumor targeting chitosan nanoparticles for dual-modality optical/MR cancer imaging. Bioconjug Chem 21(4):578-582.
-
(2010)
Bioconjug Chem
, vol.21
, Issue.4
, pp. 578-582
-
-
Nam, T.1
-
4
-
-
36749044732
-
Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer
-
Yang J, et al. (2007) Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer. Angew Chem Int Ed Engl 46(46):8836-8839.
-
(2007)
Angew Chem Int Ed Engl
, vol.46
, Issue.46
, pp. 8836-8839
-
-
Yang, J.1
-
6
-
-
79960925147
-
Targeted drug delivery to tumors: Myths, reality and possibility
-
Bae YH, Park K (2011) Targeted drug delivery to tumors: Myths, reality and possibility. J Control Release 153(3):198-205.
-
(2011)
J Control Release
, vol.153
, Issue.3
, pp. 198-205
-
-
Bae, Y.H.1
Park, K.2
-
7
-
-
84900857276
-
Nanoparticle exposure in animals can be visualized in the skin and analysed via skin biopsy
-
Sykes EA, Dai Q, Tsoi KM, Hwang DM, Chan WCW (2014) Nanoparticle exposure in animals can be visualized in the skin and analysed via skin biopsy. Nat Commun 5:3796.
-
(2014)
Nat Commun
, vol.5
, pp. 3796
-
-
Sykes, E.A.1
Dai, Q.2
Tsoi, K.M.3
Hwang, D.M.4
Chan, W.C.W.5
-
8
-
-
39649115201
-
Particle size-dependent organ distribution of gold nanoparticles after intravenous administration
-
De Jong WH, et al. (2008) Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials 29(12):1912-1919.
-
(2008)
Biomaterials
, vol.29
, Issue.12
, pp. 1912-1919
-
-
De Jong, W.H.1
-
9
-
-
79959866972
-
Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles
-
Cole AJ, David AE, Wang J, Galbán CJ, Yang VC (2011) Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles. Biomaterials 32(26):6291-6301.
-
(2011)
Biomaterials
, vol.32
, Issue.26
, pp. 6291-6301
-
-
Cole, A.J.1
David, A.E.2
Wang, J.3
Galbán, C.J.4
Yang, V.C.5
-
10
-
-
77649146256
-
In vivo biodistribution and clearance studies using multimodal organically modified silica nanoparticles
-
Kumar R, et al. (2010) In vivo biodistribution and clearance studies using multimodal organically modified silica nanoparticles. ACS Nano 4(2):699-708.
-
(2010)
ACS Nano
, vol.4
, Issue.2
, pp. 699-708
-
-
Kumar, R.1
-
11
-
-
0034996764
-
Long-circulating and target-specific nanoparticles: Theory to practice
-
Moghimi SM, Hunter AC, Murray JC (2001) Long-circulating and target-specific nanoparticles: Theory to practice. Pharmacol Rev 53(2):283-318.
-
(2001)
Pharmacol Rev
, vol.53
, Issue.2
, pp. 283-318
-
-
Moghimi, S.M.1
Hunter, A.C.2
Murray, J.C.3
-
12
-
-
84884274347
-
Nanoparticle accumulation in angiogenic tissues: Towards predictable pharmacokinetics
-
Yaehne K, et al. (2013) Nanoparticle accumulation in angiogenic tissues: Towards predictable pharmacokinetics. Small 9(18):3118-3127.
-
(2013)
Small
, vol.9
, Issue.18
, pp. 3118-3127
-
-
Yaehne, K.1
-
13
-
-
70449088926
-
The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function
-
Huang X, Teng X, Chen D, Tang F, He J (2010) The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function. Biomaterials 31(3):438-448.
-
(2010)
Biomaterials
, vol.31
, Issue.3
, pp. 438-448
-
-
Huang, X.1
Teng, X.2
Chen, D.3
Tang, F.4
He, J.5
-
14
-
-
38849085772
-
Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells
-
Hauck TS, Ghazani AA, Chan WCW (2008) Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells. Small 4(1): 153-159.
-
(2008)
Small
, vol.4
, Issue.1
, pp. 153-159
-
-
Hauck, T.S.1
Ghazani, A.A.2
Chan, W.C.W.3
-
15
-
-
84881308513
-
New views on cellular uptake and trafficking of manufactured nanoparticles
-
Treuel L, Jiang X, Nienhaus GU (2013) New views on cellular uptake and trafficking of manufactured nanoparticles. J R Soc Interface 10(82):20120939.
-
(2013)
J R Soc Interface
, vol.10
, Issue.82
-
-
Treuel, L.1
Jiang, X.2
Nienhaus, G.U.3
-
16
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown JM, Giaccia AJ (1998) The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy. Cancer Res 58(7):1408-1416.
-
(1998)
Cancer Res
, vol.58
, Issue.7
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
17
-
-
84884368877
-
Influence of tumour micro-environment heterogeneity on therapeutic response
-
Junttila MR, de Sauvage FJ (2013) Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 501(7467):346-354.
-
(2013)
Nature
, vol.501
, Issue.7467
, pp. 346-354
-
-
Junttila, M.R.1
De Sauvage, F.J.2
-
18
-
-
84906064921
-
Omics-based nanomedicine: The future of personalized oncology
-
Rosenblum D, Peer D (2014) Omics-based nanomedicine: The future of personalized oncology. Cancer Lett 352(1):126-136.
-
(2014)
Cancer Lett
, vol.352
, Issue.1
, pp. 126-136
-
-
Rosenblum, D.1
Peer, D.2
-
19
-
-
84875174768
-
The role of tumour-stromal interactions in modifying drug response: Challenges and opportunities
-
McMillin DW, Negri JM, Mitsiades CS (2013) The role of tumour-stromal interactions in modifying drug response: Challenges and opportunities. Nat Rev Drug Discov 12(3): 217-228.
-
(2013)
Nat Rev Drug Discov
, vol.12
, Issue.3
, pp. 217-228
-
-
McMillin, D.W.1
Negri, J.M.2
Mitsiades, C.S.3
-
21
-
-
77956562428
-
Diffusion of particles in the extracellular matrix: The effect of repulsive electrostatic interactions
-
Stylianopoulos T, et al. (2010) Diffusion of particles in the extracellular matrix: The effect of repulsive electrostatic interactions. Biophys J 99(5):1342-1349.
-
(2010)
Biophys J
, vol.99
, Issue.5
, pp. 1342-1349
-
-
Stylianopoulos, T.1
-
22
-
-
84859949610
-
The extracellular matrix: A dynamic niche in cancer progression
-
Lu P, Weaver VM, Werb Z (2012) The extracellular matrix: A dynamic niche in cancer progression. J Cell Biol 196(4):395-406.
-
(2012)
J Cell Biol
, vol.196
, Issue.4
, pp. 395-406
-
-
Lu, P.1
Weaver, V.M.2
Werb, Z.3
-
23
-
-
27444446567
-
Collagen and picrosirius red staining: A polarized light assessment of fibrillar hue and spatial distribution
-
Rich L, Whittaker P (2005) Collagen and picrosirius red staining: A polarized light assessment of fibrillar hue and spatial distribution. Braz J Morphol Sci 22:97-104.
-
(2005)
Braz J Morphol Sci
, vol.22
, pp. 97-104
-
-
Rich, L.1
Whittaker, P.2
-
24
-
-
84863238548
-
Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure
-
Chen X, Nadiarynkh O, Plotnikov S, Campagnola PJ (2012) Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure. Nat Protoc 7(4):654-669.
-
(2012)
Nat Protoc
, vol.7
, Issue.4
, pp. 654-669
-
-
Chen, X.1
Nadiarynkh, O.2
Plotnikov, S.3
Campagnola, P.J.4
-
25
-
-
0038578294
-
Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation
-
Brown E, et al. (2003) Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation. Nat Med 9(6):796-800.
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 796-800
-
-
Brown, E.1
-
26
-
-
84903475162
-
Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency
-
Sykes EA, Chen J, Zheng G, Chan WCW (2014) Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency. ACS Nano 8(6):5696-5706.
-
(2014)
ACS Nano
, vol.8
, Issue.6
, pp. 5696-5706
-
-
Sykes, E.A.1
Chen, J.2
Zheng, G.3
Chan, W.C.W.4
-
27
-
-
66449116301
-
Mediating tumor targeting efficiency of nanoparticles through design
-
Perrault SD, Walkey C, Jennings T, Fischer HC, Chan WCW (2009) Mediating tumor targeting efficiency of nanoparticles through design. Nano Lett 9(5):1909-1915.
-
(2009)
Nano Lett
, vol.9
, Issue.5
, pp. 1909-1915
-
-
Perrault, S.D.1
Walkey, C.2
Jennings, T.3
Fischer, H.C.4
Chan, W.C.W.5
-
28
-
-
72249085792
-
Synthesis and surface modification of highly monodispersed, spherical gold nanoparticles of 50-200 nm
-
Perrault SD, Chan WCW (2009) Synthesis and surface modification of highly monodispersed, spherical gold nanoparticles of 50-200 nm. J Am Chem Soc 131(47):17042-17043.
-
(2009)
J Am Chem Soc
, vol.131
, Issue.47
, pp. 17042-17043
-
-
Perrault, S.D.1
Chan, W.C.W.2
-
29
-
-
84878667963
-
Fluorescence-tagged gold nanoparticles for rapidly characterizing the size-dependent biodistribution in tumor models
-
Chou LYT, Chan WCW (2012) Fluorescence-tagged gold nanoparticles for rapidly characterizing the size-dependent biodistribution in tumor models. Adv Healthc Mater 1(6):714-721.
-
(2012)
Adv Healthc Mater
, vol.1
, Issue.6
, pp. 714-721
-
-
Chou, L.Y.T.1
Chan, W.C.W.2
-
30
-
-
44149123099
-
Collagen density promotes mammary tumor initiation and progression
-
Provenzano PP, et al. (2008) Collagen density promotes mammary tumor initiation and progression. BMC Med 6(1):11.
-
(2008)
BMC Med
, vol.6
, Issue.1
, pp. 11
-
-
Provenzano, P.P.1
-
31
-
-
84907899169
-
A 3D matrix platform for the rapid generation of therapeutic anti-human carcinoma monoclonal antibodies
-
Dudley DT, et al. (2014) A 3D matrix platform for the rapid generation of therapeutic anti-human carcinoma monoclonal antibodies. Proc Natl Acad Sci USA 111(41):14882-14887.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.41
, pp. 14882-14887
-
-
Dudley, D.T.1
-
32
-
-
78649270513
-
Diffusion anisotropy in collagen gels and tumors: The effect of fiber network orientation
-
Stylianopoulos T, Diop-Frimpong B, Munn LL, Jain RK (2010) Diffusion anisotropy in collagen gels and tumors: The effect of fiber network orientation. Biophys J 99(10):3119-3128.
-
(2010)
Biophys J
, vol.99
, Issue.10
, pp. 3119-3128
-
-
Stylianopoulos, T.1
Diop-Frimpong, B.2
Munn, L.L.3
Jain, R.K.4
-
33
-
-
0029059815
-
MRI of human tumor xenografts in vivo: Proton relaxation times and extracellular tumor volume
-
Jakobsen I, Lyng H, Kaalhus O, Rofstad EK (1995) MRI of human tumor xenografts in vivo: Proton relaxation times and extracellular tumor volume. Magn Reson Imaging 13(5):693-700.
-
(1995)
Magn Reson Imaging
, vol.13
, Issue.5
, pp. 693-700
-
-
Jakobsen, I.1
Lyng, H.2
Kaalhus, O.3
Rofstad, E.K.4
-
34
-
-
0033566765
-
Available volume fraction of macromolecules in the extravascular space of a fibrosarcoma: Implications for drug delivery
-
Krol A, Maresca J, Dewhirst MW, Yuan F (1999) Available volume fraction of macromolecules in the extravascular space of a fibrosarcoma: Implications for drug delivery. Cancer Res 59(16):4136-4141.
-
(1999)
Cancer Res
, vol.59
, Issue.16
, pp. 4136-4141
-
-
Krol, A.1
Maresca, J.2
Dewhirst, M.W.3
Yuan, F.4
-
35
-
-
84856436072
-
Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake
-
Walkey CD, Olsen JB, Guo H, Emili A, Chan WCW (2012) Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake. J Am Chem Soc 134(4):2139-2147.
-
(2012)
J Am Chem Soc
, vol.134
, Issue.4
, pp. 2139-2147
-
-
Walkey, C.D.1
Olsen, J.B.2
Guo, H.3
Emili, A.4
Chan, W.C.W.5
-
36
-
-
75649097879
-
Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion
-
Varin A, Mukhopadhyay S, Herbein G, Gordon S (2010) Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion. Blood 115(2):353-362.
-
(2010)
Blood
, vol.115
, Issue.2
, pp. 353-362
-
-
Varin, A.1
Mukhopadhyay, S.2
Herbein, G.3
Gordon, S.4
-
37
-
-
79961102700
-
Transition of tumor-associated macrophages from MHC class II(hi) to MHC class II(low) mediates tumor progression in mice
-
Wang B, et al. (2011) Transition of tumor-associated macrophages from MHC class II(hi) to MHC class II(low) mediates tumor progression in mice. BMC Immunol 12(1):43.
-
(2011)
BMC Immunol
, vol.12
, Issue.1
, pp. 43
-
-
Wang, B.1
-
38
-
-
84864258079
-
The effect of nanoparticle size, shape, and surface chemistry on biological systems
-
Albanese A, Tang PS, Chan WCW (2012) The effect of nanoparticle size, shape, and surface chemistry on biological systems. Annu Rev Biomed Eng 14:1-16.
-
(2012)
Annu Rev Biomed Eng
, vol.14
, pp. 1-16
-
-
Albanese, A.1
Tang, P.S.2
Chan, W.C.W.3
-
39
-
-
84987602369
-
Nanomedicines for cancer therapy: State-of-the-art and limitations to pre-clinical studies that hinder future developments
-
Dawidczyk CM, Russell LM, Searson PC (2014) Nanomedicines for cancer therapy: State-of-the-art and limitations to pre-clinical studies that hinder future developments. Front Chem 2:69.
-
(2014)
Front Chem
, vol.2
, pp. 69
-
-
Dawidczyk, C.M.1
Russell, L.M.2
Searson, P.C.3
-
40
-
-
24644464766
-
Tumor size, vascular density and proliferation as prognostic markers in GS 6 and GS 7 prostate tumors in patients with long follow-up and noncurative treatment
-
Josefsson A, et al. (2005) Tumor size, vascular density and proliferation as prognostic markers in GS 6 and GS 7 prostate tumors in patients with long follow-up and noncurative treatment. Eur Urol 48(4):577-583.
-
(2005)
Eur Urol
, vol.48
, Issue.4
, pp. 577-583
-
-
Josefsson, A.1
-
41
-
-
4544327664
-
The effect of tumor size on curability of stage I non-small cell lung cancers
-
Wisnivesky JP, Yankelevitz D, Henschke CI (2004) The effect of tumor size on curability of stage I non-small cell lung cancers. Chest 126(3):761-765.
-
(2004)
Chest
, vol.126
, Issue.3
, pp. 761-765
-
-
Wisnivesky, J.P.1
Yankelevitz, D.2
Henschke, C.I.3
-
42
-
-
84872892962
-
Effect of large tumor size on cancer-specific mortality in node-negative breast cancer
-
Yu K-D, et al. (2012) Effect of large tumor size on cancer-specific mortality in node-negative breast cancer. Mayo Clin Proc 87(12):1171-1180.
-
(2012)
Mayo Clin Proc
, vol.87
, Issue.12
, pp. 1171-1180
-
-
Yu, K.-D.1
|