Targeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: From synthesis to proof-of-concept in vitro studies

International Journal of Nanomedicine

Volumn 11, Issue , 2016, Pages 791-822

  Spadavecchia, Jolanda ^a,b   Movia, Dania ^c   Moore, Caroline ^c,d   Maguire, Ciaran Manus ^c,d   Moustaoui, Hanane ^b   Casale, Sandra ^a   Volkov, Yuri ^c,d   Prina Mello, Adriele ^c,d  

^a SORBONNE UNIVERSITÉ   (France)

^b UNIVERSITÉ PARIS 13   (France)

^c CRANN Institute   (Ireland)

^d TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Antibody drug conjugate; Doxorubicin; HERG1; Pancreatic cancer; PEGylated gold nanoparticles; Potassium channel targeting

Indexed keywords

DOXORUBICIN; GOLD NANOPARTICLE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MACROGOL; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV11.1; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; DRUG CARRIER; GOLD; MACROGOL DERIVATIVE; METAL NANOPARTICLE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PROGNOSIS; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG RELEASE; DRUG TARGETING; EC50; ENDOCYTOSIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; LC50; PANCREAS CANCER; PHYSICAL CHEMISTRY; PROTEIN EXPRESSION; ZETA POTENTIAL; APOPTOSIS; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; PANCREATIC NEOPLASMS; PATHOLOGY; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GOLD; HUMANS; IN VITRO TECHNIQUES; METAL NANOPARTICLES; PANCREATIC NEOPLASMS; POLYETHYLENE GLYCOLS; TUMOR CELLS, CULTURED;

EID: 84959386666     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S97476     Document Type: Article

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