Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice

Biomaterials

Volumn 30, Issue 10, 2009, Pages 1928-1936

  Zhang, Guodong ^a   Yang, Zhi ^a   Lu, Wei ^a   Zhang, Rui ^a   Huang, Qian ^a   Tian, Mei ^a   Li, Li ^b   Liang, Dong ^c   Li, Chun ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c TEXAS SOUTHERN UNIVERSITY   (United States)

Author keywords

Biodistribution; Gold nanoparticle; Pharmacokinetics; Polyethylene glycol; Thioctic acid

Indexed keywords

BIODISTRIBUTION; COLLOIDAL STABILITIES; CONTRAST AGENTS; DIAGNOSTIC IMAGING; DITHIOTHREITOL; DRUG CARRIERS; GOLD NANOPARTICLE; HIGH MOLECULAR WEIGHTS; IN-VIVO; LOW MOLECULAR WEIGHTS; MONOTHIOL; NUDE MOUSE; PARTICLE CHARACTERISTICS; PHOSPHATE-BUFFERED SALINES; POLYETHYLENE GLYCOL; POTENTIAL DRUGS; THIOCTIC ACID; TUMOR UPTAKES;

ACIDS; BLOOD VESSELS; CARBOXYLIC ACIDS; COENZYMES; DRUG DELIVERY; ETHYLENE GLYCOL; GLYCOLS; GOLD; LIGANDS; NANOPARTICLES; PARTICLE SIZE; PHARMACOKINETICS; POLYETHYLENE OXIDES; THERMOPLASTICS; TUMORS;

POLYETHYLENE GLYCOLS;

DITHIOTHREITOL; DRUG CARRIER; GOLD NANOPARTICLE; INDIUM 111; LIGAND; MACROGOL; MACROGOL 5000; PENTETIC ACID; PHOSPHATE BUFFERED SALINE; POLYETHYLENE DERIVATIVE; THIOCTIC ACID; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; COLLOID; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG STABILITY; DRUG UPTAKE; ENDOTHELIUM CELL; EXTRAVASATION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MATERIAL COATING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; RETICULOCYTE; RETICULOENDOTHELIAL SYSTEM; SQUAMOUS CELL CARCINOMA; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; GOLD; HUMANS; INDIUM; MAGNETIC RESONANCE SPECTROSCOPY; METAL NANOPARTICLES; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PARTICLE SIZE; POLYETHYLENE GLYCOLS; RANDOM ALLOCATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THIOCTIC ACID; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

MUS; MUS MUSCULUS;

EID: 59649083642     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.12.038     Document Type: Article

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