Pharmacokinetics, clearance, and biosafety of polyethylene glycol-coated hollow gold nanospheres

Particle and Fibre Toxicology

Volumn 11, Issue 1, 2014, Pages

  You, Jian ^a   Zhou, Jialin ^a   Zhou, Min ^b   Liu, Yang ^b   Robertson, J D ^c   Liang, Dong ^d   Van Pelt, Carolyn ^b   Li, Chun ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

^d TEXAS SOUTHERN UNIVERSITY   (United States)

Author keywords

Hollow gold nanospheres; Photothermal ablation therapy; Toxicity

Indexed keywords

ANTINEOPLASTIC AGENT; GOLD NANOPARTICLE; HOLLOW GOLD NANOSPHERE; MACROGOL; NANOSPHERE; SNAKE VENOM; UNCLASSIFIED DRUG; HOLLOW GOLD NANOPARTICLE;

ABLATION THERAPY; ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BIOSAFETY; BLOOD COMPATIBILITY; CHRONIC TOXICITY; CLINICAL CHEMISTRY; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG CLEARANCE; DRUG COATING; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG LIVER LEVEL; DRUG MUSCLE LEVEL; DRUG SAFETY; DRUG SPLEEN LEVEL; DRUG TISSUE LEVEL; FEMALE; HEMATOLOGICAL PARAMETERS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OVARY CARCINOMA; PARTICLE SIZE; PHARMACOKINETICS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SINGLE DRUG DOSE; THROMBOCYTE AGGREGATION; COMPLEMENT SYSTEM; DRUG DELIVERY SYSTEM; KIDNEY; OVARY CANCER; PHOTOTHERAPY; SPLEEN;

MUS;

ANIMALS; ANTINEOPLASTIC AGENTS; BLOOD CELL COUNT; COMPLEMENT ACTIVATION; COPPER RADIOISOTOPES; FEMALE; GOLD; HUMANS; LIVER; LLC-PK1 CELLS; LUNG; MALE; METAL NANOPARTICLES; MICE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOSPHERES; OVARIAN NEOPLASMS; PARTICLE SIZE; PLATELET AGGREGATION; POLYETHYLENE GLYCOLS; SPLEEN; SWINE; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84903883115     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-11-26     Document Type: Article

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