A safe-by-design approach to the development of gold nanoboxes as carriers for internalization into cancer cells

Biomaterials

Volumn 35, Issue 9, 2014, Pages 2543-2557

  Movia, Dania ^a   Gerard, Valerie ^a   Maguire, Ciaran Manus ^b   Jain, Namrata ^b   Bell, Alan P ^a   Nicolosi, Valeria ^a   O'Neill, Tiina ^c   Scholz, Dimitri ^c   Gun'ko, Yurii ^a   Volkov, Yuri ^a,b   Prina Mello, Adriele ^a,b  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Gold nanoboxes; High content screening and He ion microscopy; Lung cancer barrier; Safe by design; Three dimensional culture; Tiered approach

Indexed keywords

BIODEGRADABILITY; BIOLOGICAL ORGANS; CELLS; CYTOLOGY; DIAGNOSIS; GOLD; GOLD METALLOGRAPHY; MEDICAL APPLICATIONS; NANOSTRUCTURED MATERIALS; RESPIRATORY SYSTEM;

ION MICROSCOPY; LUNG CANCER; NANOBOXES; THREE-DIMENSIONAL CULTURE; TIERED APPROACH;

DISEASES;

GOLD NANOPARTICLE; PACLITAXEL;

ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; BIODEGRADATION; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; LUNG ADENOCARCINOMA; MICROENVIRONMENT; PERSONALIZED MEDICINE; PRIORITY JOURNAL;

GOLD NANOBOXES; HIGH CONTENT SCREENING AND HE-ION MICROSCOPY; LUNG CANCER BARRIER; SAFE-BY-DESIGN; THREE-DIMENSIONAL CULTURE; TIERED APPROACH;

BIOCOMPATIBLE MATERIALS; CELL DEATH; CELL LINE, TUMOR; COCULTURE TECHNIQUES; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; GELATIN; GOLD; HUMANS; NANOSTRUCTURES; NEOPLASMS; TIME FACTORS;

EID: 84895034497     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.057     Document Type: Article

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