메뉴 건너뛰기




Volumn 112, Issue 6, 2015, Pages 1076-1087

HERG1 channels drive tumour malignancy and may serve as prognostic factor in pancreatic ductal adenocarcinoma

Author keywords

EGF R; hERG1 potassium channels; molecular imaging; pancreatic ductal adenocarcinoma (PDAC); prognosis

Indexed keywords

CRE RECOMBINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; TRANSCRIPTION FACTOR PDX 1; ERG1 POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG;

EID: 84925340348     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2015.28     Document Type: Article
Times cited : (49)

References (44)
  • 1
    • 79960006148 scopus 로고    scopus 로고
    • Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancer
    • Ansari D, Rosendahl A, Elebro J, Andersson R (2011) Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancer. Br J Surg 98: 1041-1055.
    • (2011) Br J Surg , vol.98 , pp. 1041-1055
    • Ansari, D.1    Rosendahl, A.2    Elebro, J.3    Andersson, R.4
  • 3
    • 23844547384 scopus 로고    scopus 로고
    • Expression and role of hERG channels in cancer cells
    • discussion
    • Arcangeli A (2005) Expression and role of hERG channels in cancer cells. Novartis Found Symp 266: 225-232, discussion 232-4.
    • (2005) Novartis Found Symp , vol.266 , Issue.225-232 , pp. 232-234
    • Arcangeli, A.1
  • 4
    • 33751334377 scopus 로고    scopus 로고
    • Complex functional interaction between integrin receptors and ion channels
    • Arcangeli A, Becchetti A (2006) Complex functional interaction between integrin receptors and ion channels. Trends Cell Biol 16: 631-639.
    • (2006) Trends Cell Biol , vol.16 , pp. 631-639
    • Arcangeli, A.1    Becchetti, A.2
  • 6
    • 79960972788 scopus 로고    scopus 로고
    • Ion channels and transporters in cancer. 1. Ion channels and cell proliferation in cancer
    • Becchetti A (2011) Ion channels and transporters in cancer. 1. Ion channels and cell proliferation in cancer. Am J Physiol Cell Physiol 301: C255-C265.
    • (2011) Am J Physiol Cell Physiol , vol.301 , pp. C255-C265
    • Becchetti, A.1
  • 7
    • 84891943964 scopus 로고    scopus 로고
    • And loss of Smad4 mediate invasion by activating an EGFR/NF-kB axis that induces expression of MMP9 and uPA in human pancreas progenitor cells
    • Bera A, Zhao S, Cao L, Chiao PJ, Freeman JW (2013) Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-kB axis that induces expression of MMP9 and uPA in human pancreas progenitor cells. PLoS One 8: e82282.
    • PLoS One , vol.8 , pp. e82282
    • Bera, A.1    Zhao, S.2    Cao, L.3    Chiao, P.J.4    Freeman, J.W.5
  • 13
    • 0029956004 scopus 로고    scopus 로고
    • A HERG-like K+ channel in rat F-11 DRG cell line: Pharmacological identification and biophysical characterization
    • Faravelli L, Arcangeli A, Olivotto M, Wanke E (1996) A HERG-like K+ channel in rat F-11 DRG cell line: pharmacological identification and biophysical characterization. J Physiol 496(Pt 1): 13-23.
    • (1996) J Physiol , vol.496 , pp. 13-23
    • Faravelli, L.1    Arcangeli, A.2    Olivotto, M.3    Wanke, E.4
  • 21
    • 79959935959 scopus 로고    scopus 로고
    • EGFR signaling in colorectal carcinoma
    • Krasinskas AM (2011) EGFR signaling in colorectal carcinoma. Patholog Res Int 2011: 932932.
    • (2011) Patholog Res Int , vol.2011 , pp. 932932
    • Krasinskas, A.M.1
  • 24
    • 20344402781 scopus 로고    scopus 로고
    • Na+/H+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin
    • Miraglia E, Viarisio D, Riganti C, Costamagna C, Ghigo D, Bosia A (2005) Na+/H+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin. Int J Cancer 115: 924-929.
    • (2005) Int J Cancer , vol.115 , pp. 924-929
    • Miraglia, E.1    Viarisio, D.2    Riganti, C.3    Costamagna, C.4    Ghigo, D.5    Bosia, A.6
  • 28
    • 77949273925 scopus 로고    scopus 로고
    • Activation of Na+/H+ exchanger 1 by neurotensin signaling in pancreatic cancer cell lines
    • Olszewski U, Hlozek M, Hamilton G (2010) Activation of Na+/H+ exchanger 1 by neurotensin signaling in pancreatic cancer cell lines. Biochem Biophys Res Commun 393: 414-419.
    • (2010) Biochem Biophys Res Commun , vol.393 , pp. 414-419
    • Olszewski, U.1    Hlozek, M.2    Hamilton, G.3
  • 29
    • 84880065113 scopus 로고    scopus 로고
    • Toward a better understanding of pancreatic ductal adenocarcinoma: Glimmers of hope?
    • Partensky C (2013) Toward a better understanding of pancreatic ductal adenocarcinoma: glimmers of hope? Pancreas 42: 729-739.
    • (2013) Pancreas , vol.42 , pp. 729-739
    • Partensky, C.1
  • 30
    • 84875446405 scopus 로고    scopus 로고
    • Ion channels and transporters in cancer: Pathophysiology, regulation, and clinical potential
    • Pedersen SF, Stock C (2013) Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential. Cancer Res 73: 1658-1661.
    • (2013) Cancer Res , vol.73 , pp. 1658-1661
    • Pedersen, S.F.1    Stock, C.2
  • 32
    • 34548036519 scopus 로고    scopus 로고
    • VEGFR-1 (FLT-1), beta1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: Role in cell migration and clinical outcome
    • Pillozzi S, Brizzi MF, Bernabei PA, Bartolozzi B, Caporale R, Basile V, Boddi V, Pegoraro L, Becchetti A, Arcangeli A (2007) VEGFR-1 (FLT-1), beta1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: role in cell migration and clinical outcome. Blood 110: 1238-1250.
    • (2007) Blood , vol.110 , pp. 1238-1250
    • Pillozzi, S.1    Brizzi, M.F.2    Bernabei, P.A.3    Bartolozzi, B.4    Caporale, R.5    Basile, V.6    Boddi, V.7    Pegoraro, L.8    Becchetti, A.9    Arcangeli, A.10
  • 33
    • 77954664903 scopus 로고    scopus 로고
    • Physical and functional interaction between integrins and hERG1 channels in cancer cells
    • Pillozzi S, Arcangeli A (2010) Physical and functional interaction between integrins and hERG1 channels in cancer cells. Adv Exp Med Biol 674: 55-67.
    • (2010) Adv Exp Med Biol , vol.674 , pp. 55-67
    • Pillozzi, S.1    Arcangeli, A.2
  • 34
    • 77949327468 scopus 로고    scopus 로고
    • Ion channels and the hallmarks of cancer
    • Prevarskaya N, Skryma R, Shuba Y (2010) Ion channels and the hallmarks of cancer. Trends Mol Med 16: 107-121.
    • (2010) Trends Mol Med , vol.16 , pp. 107-121
    • Prevarskaya, N.1    Skryma, R.2    Shuba, Y.3
  • 35
    • 84871390701 scopus 로고    scopus 로고
    • Inside out: Targeting NHE1 as an intracellular and extracellular regulator of cancer progression
    • Provost JJ, Wallert MA (2013) Inside out: targeting NHE1 as an intracellular and extracellular regulator of cancer progression. Chem Biol Drug Des 81: 85-101.
    • (2013) Chem Biol Drug des , vol.81 , pp. 85-101
    • Provost, J.J.1    Wallert, M.A.2
  • 36
    • 0033670058 scopus 로고    scopus 로고
    • Glucose- and arginine-induced insulin secretion by human pancreatic beta-cells: The role of HERG K(+) channels in firing and release
    • Rosati B, Marchetti P, Crociani O, Lecchi M, Lupi R, Arcangeli A, Olivotto M, Wanke E (2000) Glucose- and arginine-induced insulin secretion by human pancreatic beta-cells: the role of HERG K(+) channels in firing and release. FASEB J 14: 2601-2610.
    • (2000) FASEB J , vol.14 , pp. 2601-2610
    • Rosati, B.1    Marchetti, P.2    Crociani, O.3    Lecchi, M.4    Lupi, R.5    Arcangeli, A.6    Olivotto, M.7    Wanke, E.8
  • 38
    • 84887387117 scopus 로고    scopus 로고
    • Development of novel anti-Kv 11.1 antibodyconjugated PEG-TiO2 nanoparticles for targeting pancreatic ductal adenocarcinoma cells
    • Sette A, Spadavecchia J, Landoulsi J, Casale S, Haye B, Crociani O, Arcangeli A (2013) Development of novel anti-Kv 11.1 antibodyconjugated PEG-TiO2 nanoparticles for targeting pancreatic ductal adenocarcinoma cells. J Nanopart Res 15: 2111.
    • (2013) J Nanopart Res , vol.15 , pp. 2111
    • Sette, A.1    Spadavecchia, J.2    Landoulsi, J.3    Casale, S.4    Haye, B.5    Crociani, O.6    Arcangeli, A.7
  • 39
    • 84872825716 scopus 로고    scopus 로고
    • KRAS above and beyond-EGFR in pancreatic cancer
    • Siveke JT, Crawford HC (2012) KRAS above and beyond-EGFR in pancreatic cancer. Oncotarget 3: 1262-1263.
    • (2012) Oncotarget , vol.3 , pp. 1262-1263
    • Siveke, J.T.1    Crawford, H.C.2
  • 41
    • 47749110251 scopus 로고    scopus 로고
    • An unexpected role for ion channels in brain tumor metastasis
    • Sontheimer H (2008) An unexpected role for ion channels in brain tumor metastasis. Exp Biol Med 233: 779-791.
    • (2008) Exp Biol Med , vol.233 , pp. 779-791
    • Sontheimer, H.1
  • 42
    • 0033565875 scopus 로고    scopus 로고
    • Modulation of glioma cell migration and invasion using Cl(-) and K(+) ion channel blockers
    • Soroceanu L, Manning Jr TJ, Sontheimer H (1999) Modulation of glioma cell migration and invasion using Cl(-) and K(+) ion channel blockers. J Neurosci 19: 5942-5954.
    • (1999) J Neurosci , vol.19 , pp. 5942-5954
    • Soroceanu, L.1    Manning, T.J.2    Sontheimer, H.3
  • 43
    • 0028094350 scopus 로고
    • An exaltation of experts: Concerted efforts in the standardization of immunohistochemistry
    • Taylor CR (1994) An exaltation of experts: concerted efforts in the standardization of immunohistochemistry. Hum Pathol 25: 2-11.
    • (1994) Hum Pathol , vol.25 , pp. 2-11
    • Taylor, C.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.