Synergistic antihypertensive effect of carthamus tinctorius L. extract and captopril in L-NAME-induced hypertensive rats via restoration of eNOS and AT1R expression

Nutrients

Volumn 8, Issue 3, 2016, Pages

  Maneesai, Putcharawipa ^a   Prasarttong, Patoomporn ^a   Bunbupha, Sarawoot ^b   Kukongviriyapan, Upa ^a   Kukongviriyapan, Veerapol ^a   Tangsucharit, Panot ^a   Prachaney, Parichat ^a   Pakdeechote, Poungrat ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

^b Nakhonratchasima Technical College   (Thailand)

Author keywords

Captopril; Carthamus tinctorius L; ENOS expression; L NAME induced hypertension; Oxidative stress; Renin angiotensin system

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CAPTOPRIL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MALONALDEHYDE; N(G) NITROARGININE METHYL ESTER; NITROPRUSSIDE SODIUM; SAFFLOWER EXTRACT; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; NITRIC OXIDE; NOS3 PROTEIN, RAT; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD VESSEL REACTIVITY; CHEMOLUMINESCENCE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; GENE EXPRESSION REGULATION; HEART RATE; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; METABOLITE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PULSE PRESSURE; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SAFFLOWER; SYSTOLIC BLOOD PRESSURE; VASCULAR RESISTANCE; VASCULAR RING; VASODILATATION; WESTERN BLOTTING; ANIMAL; BLOOD PRESSURE; CHEMICALLY INDUCED; CHEMISTRY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; DRUG POTENTIATION; ENZYMOLOGY; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METABOLISM; PATHOPHYSIOLOGY; PHYTOTHERAPY; SPRAGUE DAWLEY RAT; TIME FACTOR;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CAPTOPRIL; CARTHAMUS TINCTORIUS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; HYPERTENSION; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN-ANGIOTENSIN SYSTEM; TIME FACTORS; VASODILATION;

EID: 84959386489     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu8030122     Document Type: Article

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