Asiatic acid reduces blood pressure by enhancing nitric oxide bioavailability with modulation of eNOS and p47phox expression in L-NAME-induced hypertensive rats

Phytotherapy Research

Volumn 28, Issue 10, 2014, Pages 1506-1512

  Bunbupha, Sarawoot ^a   Pakdeechote, Poungrat ^a   Kukongviriyapan, Upa ^a   Prachaney, Parichat ^b   Kukongviriyapan, Veerapol ^b  

^a KHON KAEN UNIVERSITY   (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

Author keywords

asiatic acid; hypertension; nitric oxide; oxidative stress; vascular dysfunction

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; ASIATIC ACID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; ANTIHYPERTENSIVE AGENT; MALONALDEHYDE; NEUTROPHIL CYTOSOLIC FACTOR 1; NITRIC OXIDE; NOS3 PROTEIN, RAT; PENTACYCLIC TRITERPENE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR RESPONSE; DIASTOLIC BLOOD PRESSURE; DOWN REGULATION; DRUG EFFICACY; DRUG RESPONSE; HEART HEMODYNAMICS; HYPERTENSION; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SYSTOLIC BLOOD PRESSURE; UPREGULATION; VASOCONSTRICTION; VASODILATATION; ANIMAL; BIOAVAILABILITY; BLOOD; BLOOD PRESSURE; CHEMICALLY INDUCED; DRUG EFFECTS; HEMODYNAMICS; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BIOLOGICAL AVAILABILITY; BLOOD PRESSURE; HEMODYNAMICS; HYPERTENSION; MALE; MALONDIALDEHYDE; NADPH OXIDASE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PENTACYCLIC TRITERPENES; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDES;

EID: 84908554407     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5156     Document Type: Article

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