Protective effects of quercetin against phenylhydrazine-induced vascular dysfunction and oxidative stress in rats

Food and Chemical Toxicology

Volumn 45, Issue 3, 2007, Pages 448-455

  Luangaram, Saowanee ^a   Kukongviriyapan, Upa ^a   Pakdeechote, Poungrat ^a   Kukongviriyapan, Veerapol ^a   Pannangpetch, Patchareewan ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

Author keywords

Antioxidant; Hemolytic anemia; Phenylhydrazine; Quercetin; Reactive oxygen species; Vascular dysfunction

Indexed keywords

ACETYLCHOLINE; ANTIOXIDANT; BRADYKININ; GLUTATHIONE; MALONALDEHYDE; PHENYLEPHRINE; PHENYLHYDRAZINE; QUERCETIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEMODYNAMICS; HEMOLYSIS; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXIDATIVE STRESS; RAT; SPRAGUE DAWLEY RAT; VASCULAR DISEASE; VASCULAR RESISTANCE;

ADMINISTRATION, ORAL; ANEMIA, HEMOLYTIC; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; OXIDATIVE STRESS; PHENYLHYDRAZINES; PHYTOTHERAPY; PLANTS, MEDICINAL; PROTECTIVE AGENTS; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR RESISTANCE;

ANIMALIA; RATTUS;

EID: 33846590591     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.09.008     Document Type: Article

References (55)

1. Afanas'ev I.B., Ostrachovitch E.A., Abramova N.E., and Korkina L.G. Different antioxidant activities of bioflavonoid rutin in normal and iron-overloading rats. Biochem. Pharmacol. 50 (1995) 627-635
2. Altavilla D., Saitta A., Guarini S., Galeano M., Squadrito G., Santamaria L.B., Venuti F.S., Bazzani C., Bertolini A., and Squadrito F. Nuclear factor-kappaB as a target of cyclosporin in acute hypovolemic hemorrhagic shock. Cardiovasc. Res. 52 (2001) 143-152
3. Ardanaz N., and Pagano P.J. Hydrogen peroxide as a paracrine vascular mediator: regulation and signaling leading to dysfunction. Exp. Biol. Med. (Maywood) 23 (2006) 237-251
4. Behrendt D., and Ganz P. Endothelial function. From vascular biology to clinical applications. Am. J. Cardiol. 90 (2002) 40L-48L
5. Brugnara C., and de Franceschi L. Effect of cell age and phenylhydrazine on the cation transport properties of rabbit erythrocytes. J. Cell. Physiol. 154 (1993) 271-280
6. Cai H. NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease. Circ. Res. 96 (2005) 818-822
7. Cai H., and Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 87 (2000) 840-844
8. Chakrabarti S., Sonaye B., Naik A.A., and Nadkarni P.P. Erythrocyte membrane protein damage by oxidation products of phenylhydrazine. Biochem. Mol. Biol. Int. 35 (1995) 255-263
9. Choi Y.J., Kang J.S., Park J.H., Lee Y.J., Choi J.S., and Kang Y.H. Polyphenolic flavonoids differ in their antiapoptotic efficacy in hydrogen peroxide-treated human vascular endothelial cells. J. Nutr. 133 (2003) 985-991
10. Draper H.H., Squires E.J., Mahmoodi H., Wu J., Agarwal S., and Hadley M. A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials. Free Radic. Biol. Med. 15 (1993) 353-363
11. Ferrali M., Signorini C., Caciotti B., Sugherini L., Ciccoli L., Giachetti D., and Comporti M. Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity. FEBS Lett. 416 (1997) 123-129
12. Ferrali M., Signorini C., Ciccoli L., Bambagioni S., Rossi V., Pompella A., and Comporti M. Protection of erythrocytes against oxidative damage and autologous immunoglobulin G (IgG) binding by iron chelator fluor-benzoil-pyridoxal hydrazone. Biochem. Pharmacol. 59 (2000) 1365-1373
13. Forstermann U., and Munzel T. Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation 113 (2006) 1708-1714
14. Garcia-Saura M.F., Galisteo M., Villar I.C., Bermejo A., Zarzuelo A., Vargas F., and Duarte J. Effects of chronic quercetin treatment in experimental renovascular hypertension. Mol. Cell. Biochem. 270 (2005) 147-155
15. Goldberg B., and Stern A. The mechanism of oxidative hemolysis produced by phenylhydrazine. Mol. Pharmacol. 13 (1977) 832-839
16. Griendling K.K., and FitzGerald G.A. Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 108 (2003) 2034-2040
17. Halliwell B., Rafter J., and Jenner A. Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not?. Am. J. Clin. Nutr. 81 (2005) 268S-276S
18. Hanasaki Y., Ogawa S., and Fukui S. The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radic. Biol. Med. 16 (1994) 845-850
19. Hertog M.G., Feskens E.J., Hollman P.C., Katan M.B., and Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 342 (1993) 1007-1011
20. Hertog M.G., Hollman P.C., Katan M.B., and Kromhout D. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. Nutr. Cancer 20 (1993) 21-29
21. Hertog M.G., Feskens E.J., Hollman P.C., Katan M.B., and Kromhout D. Dietary flavonoids and cancer risk in the Zutphen Elderly Study. Nutr. Cancer 22 (1994) 175-184
22. Hirano R., Sasamoto W., Matsumoto A., Itakura H., Igarashi O., and Kondo K. Antioxidant ability of various flavonoids against DPPH radicals and LDL oxidation. J. Nutr. Sci. Vitaminol. (Tokyo) 47 (2001) 357-362
23. Hollman P.C., and Katan M.B. Dietary flavonoids: intake, health effects and bioavailability. Food Chem. Toxicol. 37 (1999) 937-942
24. Huxley R.R., and Neil H.A. The relation between dietary flavonol intake and coronary heart disease mortality: a meta-analysis of prospective cohort studies. Eur. J. Clin. Nutr. 57 (2003) 904-908
25. Ignarro L.J., Wood K.S., Ballot B., and Wolin M.S. Guanylate cyclase from bovine lung. Evidence that enzyme activation by phenylhydrazine is mediated by iron-phenyl hemoprotein complexes. J. Biol. Chem. 259 (1984) 5923-5931
26. Ishige K., Schubert D., and Sagara Y. Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Radic. Biol. Med. 30 (2001) 433-446
27. Itano H.A., Hirota K., and Hosokawa K. Mechanism of induction of haemolytic anaemia by phenylhydrazine. Nature 256 (1975) 665-667
28. Korkina L.G., and Afanas'ev I.B. Antioxidant and chelating properties of flavonoids. Adv. Pharmacol. 38 (1997) 151-163
29. Kukongviriyapan U., Luangaram S., Kukongviriyapan V., and Pannangpetch P. Desferrioxamine protects phenylhydrazine-induced oxidative stress and vascular dysfunction. Faseb. J. 19 (2005) A704
30. Kuo S.M. Dietary flavonoid and cancer prevention: evidence and potential mechanism. Crit. Rev. Oncog. 8 (1997) 47-69
31. Liese A.M., Siddiqi M.Q., Siegel J.H., Denny T., and Spolarics Z. Augmented TNF-alpha and IL-10 production by primed human monocytes following interaction with oxidatively modified autologous erythrocytes. J. Leukoc. Biol. 70 (2001) 289-296
32. Lu F.J., Lin J.T., Wang H.P., and Huang W.C. A simple, sensitive, non-stimulated photon counting system for detection of superoxide anion in whole blood. Experientia 52 (1996) 141-144
33. Misra H.P., and Fridovich I. The oxidation of phenylhydrazine: superoxide and mechanism. Biochemistry 15 (1976) 681-687
34. Nakamura Y., Tsuji S., and Tonogai Y. Determination of the levels of isoflavonoids in soybeans and soy-derived foods and estimation of isoflavonoids in the Japanese daily intake. J. AOAC Int. 83 (2000) 635-650
35. Nassberger L., Johansson A.C., Bjorck S., and Sjoholm A.G. Antibodies to neutrophil granulocyte myeloperoxidase and elastase: autoimmune responses in glomerulonephritis due to hydralazine treatment. J. Intern. Med. 229 (1991) 261-265
36. Nicolas G., Chauvet C., Viatte L., Danan J.L., Bigard X., Devaux I., Beaumont C., Kahn A., and Vaulont S. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 110 (2002) 1037-1044
37. Parodi S., De Flora S., Cavanna M., Pino A., Robbiano L., Bennicelli C., and Brambilla G. DNA-damaging activity in vivo and bacterial mutagenicity of sixteen hydrazine derivatives as related quantitatively to their carcinogenicity. Cancer Res. 41 (1981) 1469-1482
38. Pavanato A., Tunon M.J., Sanchez-Campos S., Marroni C.A., Llesuy S., Gonzalez-Gallego J., and Marroni N. Effects of quercetin on liver damage in rats with carbon tetrachloride-induced cirrhosis. Dig. Dis. Sci. 48 (2003) 824-829
39. Piepot H.A., Groeneveld A.B., van Lambalgen A.A., and Sipkema P. The role of inducible nitric oxide synthase in lipopolysaccharide-mediated hyporeactivity to vasoconstrictors differs among isolated rat arteries. Clin. Sci. (Lond) 102 (2002) 297-305
40. Quyyumi A.A. Endothelial function in health and disease: new insights into the genesis of cardiovascular disease. Am. J. Med. 105 (1998) 32S-39S
41. Rice-Evans C.A., Miller N.J., Bolwell P.G., Bramley P.M., and Pridham J.B. The relative antioxidant activities of plant-derived polyphenolic flavonoids. Free Radic. Res. 22 (1995) 375-383
42. Richter M., Ebermann R., and Marian B. Quercetin-induced apoptosis in colorectal tumor cells: possible role of EGF receptor signaling. Nutr. Cancer 34 (1999) 88-99
43. Rodriguez-Porcel M., Lerman L.O., Herrmann J., Sawamura T., Napoli C., and Lerman A. Hypercholesterolemia and hypertension have synergistic deleterious effects on coronary endothelial function. Arterioscler Thromb. Vasc. Biol. 23 (2003) 885-891
44. Sanchez M., Galisteo M., Vera R., Villar I.C., Zarzuelo A., Tamargo J., Perez-Vizcaino F., and Duarte J. Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats. J. Hypertens. 24 (2006) 75-84
45. Scalbert A., and Williamson G. Dietary intake and bioavailability of polyphenols. J. Nutr. 130 (2000) 2073S-2085S
46. Shetlar M.D., and Hill H.A. Reactions of hemoglobin with phenylhydrazine: a review of selected aspects. Environ. Health Perspect. 64 (1985) 265-281
47. Sorata Y., Takahama U., and Kimura M. Protective effect of quercetin and rutin on photosensitized lysis of human erythrocytes in the presence of hematoporphyrin. Biochim. Biophys. Acta 799 (1984) 313-317
48. Stoclet J.C., Chataigneau T., Ndiaye M., Oak M.H., El Bedoui J., Chataigneau M., and Schini-Kerth V.B. Vascular protection by dietary polyphenols. Eur. J. Pharmacol. 500 (2004) 299-313
49. Swann J.W., and Contrera J.F. Depletion of cardiac norepinephrine during two forms of hemolytic anemia in the rat. Circ. Res. 38 (1976) 179-184
50. Taniyama Y., and Griendling K.K. Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 42 (2003) 1075-1081
51. Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27 (1969) 502-522
52. van Acker S.A., Tromp M.N., Haenen G.R., van der Vijgh W.J., and Bast A. Flavonoids as scavengers of nitric oxide radical. Biochem. Biophys. Res. Commun. 214 (1995) 755-759
53. Verdon C.P., Burton B.A., and Prior R.L. Sample pretreatment with nitrate reductase and glucose-6-phosphate dehydrogenase quantitatively reduces nitrate while avoiding interference by NADP+ when the Griess reaction is used to assay for nitrite. Anal. Biochem. 224 (1995) 502-508
54. Vidrio H., Fernandez G., Medina M., Alvarez E., and Orallo F. Effects of hydrazine derivatives on vascular smooth muscle contractility, blood pressure and cGMP production in rats: comparison with hydralazine. Vascul. Pharmacol. 40 (2003) 13-21
55. Wilcox C.S., and Gutterman D. Focus on oxidative stress in the cardiovascular and renal systems. Am. J. Physiol. Heart Circ. Physiol. 288 (2005) H3-H6