-
1
-
-
84929414196
-
Lymphoma: Immune evasion strategies
-
Upadhyay R, Hammerich L, Peng P, Brown B, Merad M, Brody JD. Lymphoma: immune evasion strategies. Cancers (Basel) 7(2), 736-762 (2015
-
(2015)
Cancers (Basel
, vol.7
, Issue.2
, pp. 736-762
-
-
Upadhyay, R.1
Hammerich, L.2
Peng, P.3
Brown, B.4
Merad, M.5
Brody, J.D.6
-
2
-
-
84921754838
-
Tumour immunogenicity, antigen presentation and immunological barriers in cancer immunotherapy
-
734515
-
Escors D. Tumour immunogenicity, antigen presentation and immunological barriers in cancer immunotherapy. New J. Sci. 2014, pii: 734515 (2014
-
(2014)
New J. Sci
, vol.2014
-
-
Escors, D.1
-
3
-
-
6344280421
-
Dendritic cells in vaccination therapies of human malignant disease
-
Reichardt VL, Brossart P, Kanz L. Dendritic cells in vaccination therapies of human malignant disease. Blood Rev. 18(4), 235-243 (2004
-
(2004)
Blood Rev
, vol.18
, Issue.4
, pp. 235-243
-
-
Reichardt, V.L.1
Brossart, P.2
Kanz, L.3
-
4
-
-
0035889949
-
Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory
-
Suresh M, Whitmire JK, Harrington LE, et al. Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory. J. Immunol. 167(10), 5565-5573 (2001
-
(2001)
J. Immunol
, vol.167
, Issue.10
, pp. 5565-5573
-
-
Suresh, M.1
Whitmire, J.K.2
Harrington, L.E.3
-
5
-
-
0033975857
-
Functional responses and costimulator dependence of memory CD4+ T cells
-
London CA, Lodge MP, Abbas AK. Functional responses and costimulator dependence of memory CD4+ T cells. J. Immunol. 164(1), 265-272 (2000
-
(2000)
J. Immunol
, vol.164
, Issue.1
, pp. 265-272
-
-
London, C.A.1
Lodge, M.P.2
Abbas, A.K.3
-
7
-
-
84883642231
-
Oncolytic viruses as therapeutic cancer vaccines
-
Bartlett DL, Liu Z, Sathaiah M, et al. Oncolytic viruses as therapeutic cancer vaccines. Mol. Cancer 12(1), 103 (2013
-
(2013)
Mol. Cancer
, vol.12
, Issue.1
, pp. 103
-
-
Bartlett, D.L.1
Liu, Z.2
Sathaiah, M.3
-
8
-
-
0034608387
-
Cross-presentation of glycoprotein 96-Associated antigens on major histocompatibility complex class i molecules requires receptor-mediated endocytosis
-
Singh-Jasuja H, Toes RE, Spee P, et al. Cross-presentation of glycoprotein 96-Associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis. J. Exp. Med. 191(11), 1965-1974 (2000
-
(2000)
J. Exp. Med
, vol.191
, Issue.11
, pp. 1965-1974
-
-
Singh-Jasuja, H.1
Toes, R.E.2
Spee, P.3
-
9
-
-
0037111218
-
Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells
-
Noessner E, Gastpar R, Milani V, et al. Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells. J. Immunol. 169(10), 5424-5432 (2002
-
(2002)
J. Immunol
, vol.169
, Issue.10
, pp. 5424-5432
-
-
Noessner, E.1
Gastpar, R.2
Milani, V.3
-
10
-
-
46749085802
-
An adjuvant autologous therapeutic vaccine (HSPPC-96; Vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: A multicentre, openlabel, randomised Phase III trial
-
Wood C, Srivastava P, Bukowski R, et al. An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, openlabel, randomised Phase III trial. Lancet 372(9633), 145-154 (2008
-
(2008)
Lancet
, vol.372
, Issue.9633
, pp. 145-154
-
-
Wood, C.1
Srivastava, P.2
Bukowski, R.3
-
11
-
-
10744224810
-
A broadly applicable, personalized heat shock protein-mediated oncolytic tumor vaccine
-
Huang XF, Ren W, Rollins L, et al. A broadly applicable, personalized heat shock protein-mediated oncolytic tumor vaccine. Cancer Res. 63(21), 7321-7329 (2003
-
(2003)
Cancer Res
, vol.63
, Issue.21
, pp. 7321-7329
-
-
Huang, X.F.1
Ren, W.2
Rollins, L.3
-
12
-
-
84861213525
-
Enhanced antitumoral efficacy and immune response following conditionally replicative adenovirus containing constitutive HSF1 delivery to rodent tumors
-
Fan R, Wang C, Wang Y, et al. Enhanced antitumoral efficacy and immune response following conditionally replicative adenovirus containing constitutive HSF1 delivery to rodent tumors. J. Transl. Med. 10, 101 (2012
-
(2012)
J. Transl. Med
, vol.10
, pp. 101
-
-
Fan, R.1
Wang, C.2
Wang, Y.3
-
13
-
-
77951788053
-
HSF1 overexpression enhances oncolytic effect of replicative adenovirus
-
Wang C, Dai Z, Fan R, Deng Y, Lv G, Lu G. HSF1 overexpression enhances oncolytic effect of replicative adenovirus. J. Transl. Med. 8, 44 (2010
-
(2010)
J. Transl. Med
, vol.8
, pp. 44
-
-
Wang, C.1
Dai, Z.2
Fan, R.3
Deng, Y.4
Lv, G.5
Lu, G.6
-
14
-
-
62549085594
-
A Phase i trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients
-
Li JL, Liu HL, Zhang XR, et al. A Phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients. Gene Ther. 16(3), 376-382 (2009
-
(2009)
Gene Ther
, vol.16
, Issue.3
, pp. 376-382
-
-
Li, J.L.1
Liu, H.L.2
Zhang, X.R.3
-
15
-
-
84951781991
-
Oncolytic adenoviruses in cancer treatment
-
Alemany R. Oncolytic adenoviruses in cancer treatment. Biomedicines 2(1), 36-49 (2014
-
(2014)
Biomedicines
, vol.2
, Issue.1
, pp. 36-49
-
-
Alemany, R.1
-
16
-
-
70349864985
-
Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus
-
Bridle BW, Boudreau JE, Lichty BD, et al. Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus. Mol. Ther. 17(10), 1814-1821 (2009
-
(2009)
Mol. Ther
, vol.17
, Issue.10
, pp. 1814-1821
-
-
Bridle, B.W.1
Boudreau, J.E.2
Lichty, B.D.3
-
17
-
-
77955176474
-
Potentiating cancer immunotherapy using an oncolytic virus
-
Bridle BW, Stephenson KB, Boudreau JE, et al. Potentiating cancer immunotherapy using an oncolytic virus. Mol. Ther. 18(8), 1430-1439 (2010
-
(2010)
Mol. Ther
, vol.18
, Issue.8
, pp. 1430-1439
-
-
Bridle, B.W.1
Stephenson, K.B.2
Boudreau, J.E.3
-
18
-
-
84907521153
-
Primary overall survival (OS) from OPTiM, a randomized Phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colonystimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma
-
Abstract 9008a
-
Kaufman HL, Ingemar Andtbacka RH, Collichio FA, et al. Primary overall survival (OS) from OPTiM, a randomized Phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colonystimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma. J. Clin. Oncol. 32(SUPPL 5s), Abstract 9008a (2014
-
(2014)
J. Clin. Oncol
, vol.32
, Issue.SUPPL. 5
-
-
Kaufman, H.L.1
Ingemar Andtbacka, R.H.2
Collichio, F.A.3
-
19
-
-
43049124141
-
Arming parvoviruses with CpG motifs to improve their oncosuppressive capacity
-
Raykov Z, Grekova S, Leuchs B, Aprahamian M, Rommelaere J. Arming parvoviruses with CpG motifs to improve their oncosuppressive capacity. Int. J. Cancer 122(12), 2880-2884 (2008
-
(2008)
Int. J. Cancer
, vol.122
, Issue.12
, pp. 2880-2884
-
-
Raykov, Z.1
Grekova, S.2
Leuchs, B.3
Aprahamian, M.4
Rommelaere, J.5
-
20
-
-
84869089109
-
An oncolytic adenovirus enhanced for Toll-like receptor 9 stimulation increases antitumor immune responses and tumor clearance
-
Cerullo V, Diaconu I, Romano V, et al. An oncolytic adenovirus enhanced for Toll-like receptor 9 stimulation increases antitumor immune responses and tumor clearance. Mol. Ther. 20(11), 2076-2086 (2012
-
(2012)
Mol. Ther
, vol.20
, Issue.11
, pp. 2076-2086
-
-
Cerullo, V.1
Diaconu, I.2
Romano, V.3
-
21
-
-
84873413878
-
The efficacy versus toxicity profile of combination virotherapy and TLR immunotherapy highlights the danger of administering TLR agonists to oncolytic virus-Treated mice
-
Rommelfanger DM, Compte M, Grau MC, et al. The efficacy versus toxicity profile of combination virotherapy and TLR immunotherapy highlights the danger of administering TLR agonists to oncolytic virus-Treated mice. Mol. Ther. 21(2), 348-357 (2013
-
(2013)
Mol. Ther
, vol.21
, Issue.2
, pp. 348-357
-
-
Rommelfanger, D.M.1
Compte, M.2
Grau, M.C.3
-
22
-
-
84859443203
-
The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers
-
Parato KA, Breitbach CJ, Le Boeuf F, et al. The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers. Mol. Ther. 20(4), 749-758 (2012
-
(2012)
Mol. Ther
, vol.20
, Issue.4
, pp. 749-758
-
-
Parato, K.A.1
Breitbach, C.J.2
Le Boeuf, F.3
-
23
-
-
33746916507
-
Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF
-
Kim JH, Oh JY, Park BH, et al. Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF. Mol. Ther. 14(3), 361-370 (2006
-
(2006)
Mol. Ther
, vol.14
, Issue.3
, pp. 361-370
-
-
Kim, J.H.1
Oh, J.Y.2
Park, B.H.3
-
24
-
-
80052406557
-
Intravenous delivery of a multi-mechanistic cancer-Targeted oncolytic poxvirus in humans
-
Breitbach CJ, Burke J, Jonker D, et al. Intravenous delivery of a multi-mechanistic cancer-Targeted oncolytic poxvirus in humans. Nature 477(7362), 99-102 (2011
-
(2011)
Nature
, vol.477
, Issue.7362
, pp. 99-102
-
-
Breitbach, C.J.1
Burke, J.2
Jonker, D.3
-
25
-
-
84874309252
-
Oncolytic vaccinia virus disrupts tumor-Associated vasculature in humans
-
Breitbach CJ, Arulanandam R, De Silva N, et al. Oncolytic vaccinia virus disrupts tumor-Associated vasculature in humans. Cancer Res. 73(4), 1265-1275 (2013
-
(2013)
Cancer Res
, vol.73
, Issue.4
, pp. 1265-1275
-
-
Breitbach, C.J.1
Arulanandam, R.2
De Silva, N.3
-
26
-
-
84875225339
-
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
-
Heo J, Reid T, Ruo L, et al. Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer. Nat. Med. 19(3), 329-336 (2013
-
(2013)
Nat. Med
, vol.19
, Issue.3
, pp. 329-336
-
-
Heo, J.1
Reid, T.2
Ruo, L.3
-
27
-
-
44249100151
-
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: A Phase i trial
-
Park BH, Hwang T, Liu TC, et al. Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a Phase I trial. Lancet Oncol. 9(6), 533-542 (2008
-
(2008)
Lancet Oncol
, vol.9
, Issue.6
, pp. 533-542
-
-
Park, B.H.1
Hwang, T.2
Liu, T.C.3
-
28
-
-
80053564947
-
A mechanistic proofof-concept clinical trial with JX-594, a targeted multimechanistic oncolytic poxvirus, in patients with metastatic melanoma
-
Hwang TH, Moon A, Burke J, et al. A mechanistic proofof-concept clinical trial with JX-594, a targeted multimechanistic oncolytic poxvirus, in patients with metastatic melanoma. Mol. Ther. 19(10), 1913-1922 (2011
-
(2011)
Mol. Ther
, vol.19
, Issue.10
, pp. 1913-1922
-
-
Hwang, T.H.1
Moon, A.2
Burke, J.3
-
29
-
-
0037295403
-
ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-Tumour properties
-
Liu BL, Robinson M, Han ZQ, et al. ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-Tumour properties. Gene Ther. 10(4), 292-303 (2003
-
(2003)
Gene Ther
, vol.10
, Issue.4
, pp. 292-303
-
-
Liu, B.L.1
Robinson, M.2
Han, Z.Q.3
-
30
-
-
77955104827
-
Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck
-
Harrington KJ, Hingorani M, Tanay MA, et al. Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck. Clin. Cancer Res. 16(15), 4005-4015 (2010
-
(2010)
Clin. Cancer Res
, vol.16
, Issue.15
, pp. 4005-4015
-
-
Harrington, K.J.1
Hingorani, M.2
Tanay, M.A.3
-
31
-
-
33845336115
-
A Phase i study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colonystimulating factor
-
Hu JC, Coffin RS, Davis CJ, et al. A Phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colonystimulating factor. Clin. Cancer Res. 12(22), 6737-6747 (2006
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.22
, pp. 6737-6747
-
-
Hu, J.C.1
Coffin, R.S.2
Davis, C.J.3
-
32
-
-
73349133717
-
Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma
-
Senzer NN, Kaufman HL, Amatruda T, et al. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma. J. Clin. Oncol. 27(34), 5763-5771 (2009
-
(2009)
J. Clin. Oncol
, vol.27
, Issue.34
, pp. 5763-5771
-
-
Senzer, N.N.1
Kaufman, H.L.2
Amatruda, T.3
-
33
-
-
77149141965
-
Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma
-
Kaufman HL, Kim DW, Deraffele G, Mitcham J, Coffin RS, Kim-Schulze S. Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma. Ann. Surg. Oncol. 17(3), 718-730 (2010
-
(2010)
Ann. Surg. Oncol
, vol.17
, Issue.3
, pp. 718-730
-
-
Kaufman, H.L.1
Kim, D.W.2
Deraffele, G.3
Mitcham, J.4
Coffin, R.S.5
Kim-Schulze, S.6
-
34
-
-
84905008082
-
Primary analysis of a Phase 1b multicenter trial to evaluate safety and efficacy of talimogene laherparepvec (T-VEC) and ipilimumab (IPI) in previously untreated, unresected stage IIIB-IV melanoma
-
Abstract 9029
-
Puzanov I, Milhem MM, Ingemar Andtbacka RH, et al. Primary analysis of a Phase 1b multicenter trial to evaluate safety and efficacy of talimogene laherparepvec (T-VEC) and ipilimumab (IPI) in previously untreated, unresected stage IIIB-IV melanoma. J. Clin. Oncol. 32(SUPPL 5s), Abstract 9029 (2014
-
(2014)
J. Clin. Oncol
, vol.32
, Issue.SUPPL. 5
-
-
Puzanov, I.1
Milhem, M.M.2
Ingemar Andtbacka, R.H.3
-
35
-
-
0036005890
-
Interleukin-12 in anti-Tumor immunity and immunotherapy
-
Colombo MP, Trinchieri G. Interleukin-12 in anti-Tumor immunity and immunotherapy. Cytokine Growth Factor Rev. 13(2), 155-168 (2002
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, Issue.2
, pp. 155-168
-
-
Colombo, M.P.1
Trinchieri, G.2
-
36
-
-
0034980245
-
Interleukin 12 secretion enhances antitumor efficacy of oncolytic herpes simplex viral therapy for colorectal cancer
-
Bennett JJ, Malhotra S, Wong RJ, et al. Interleukin 12 secretion enhances antitumor efficacy of oncolytic herpes simplex viral therapy for colorectal cancer. Ann. Surg. 233(6), 819-826 (2001
-
(2001)
Ann. Surg
, vol.233
, Issue.6
, pp. 819-826
-
-
Bennett, J.J.1
Malhotra, S.2
Wong, R.J.3
-
37
-
-
32844475008
-
Enhanced therapeutic efficacy of IL-12, but not GMCSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers
-
Varghese S, Rabkin SD, Liu R, Nielsen PG, Ipe T, Martuza RL. Enhanced therapeutic efficacy of IL-12, but not GMCSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers. Cancer Gene Ther. 13(3), 253-265 (2006
-
(2006)
Cancer Gene Ther
, vol.13
, Issue.3
, pp. 253-265
-
-
Varghese, S.1
Rabkin, S.D.2
Liu, R.3
Nielsen, P.G.4
Ipe, T.5
Martuza, R.L.6
-
38
-
-
84878664183
-
Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models
-
Zhang W, Fulci G, Wakimoto H, et al. Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models. Neoplasia 15(6), 591-599 (2013
-
(2013)
Neoplasia
, vol.15
, Issue.6
, pp. 591-599
-
-
Zhang, W.1
Fulci, G.2
Wakimoto, H.3
-
39
-
-
84880376084
-
Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model
-
Cheema TA, Wakimoto H, Fecci PE, et al. Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model. Proc. Natl Acad. Sci. USA 110(29), 12006-12011 (2013
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, Issue.29
, pp. 12006-12011
-
-
Cheema, T.A.1
Wakimoto, H.2
Fecci, P.E.3
-
40
-
-
84860520650
-
Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus
-
Diaconu I, Cerullo V, Hirvinen ML, et al. Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus. Cancer Res. 72(9), 2327-2338 (2012
-
(2012)
Cancer Res
, vol.72
, Issue.9
, pp. 2327-2338
-
-
Diaconu, I.1
Cerullo, V.2
Hirvinen, M.L.3
-
41
-
-
84859376777
-
Oncolytic immunotherapy of advanced solid tumors with a CD40Lexpressing replicating adenovirus: Assessment of safety and immunologic responses in patients
-
Pesonen S, Diaconu I, Kangasniemi L, et al. Oncolytic immunotherapy of advanced solid tumors with a CD40Lexpressing replicating adenovirus: assessment of safety and immunologic responses in patients. Cancer Res. 72(7), 1621-1631 (2012
-
(2012)
Cancer Res
, vol.72
, Issue.7
, pp. 1621-1631
-
-
Pesonen, S.1
Diaconu, I.2
Kangasniemi, L.3
-
42
-
-
28244502278
-
Triple gene-deleted oncolytic herpes simplex virus vector doublearmed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system
-
Fukuhara H, Ino Y, Kuroda T, Martuza RL, Todo T. Triple gene-deleted oncolytic herpes simplex virus vector doublearmed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system. Cancer Res. 65(23), 10663-10668 (2005
-
(2005)
Cancer Res
, vol.65
, Issue.23
, pp. 10663-10668
-
-
Fukuhara, H.1
Ino, Y.2
Kuroda, T.3
Martuza, R.L.4
Todo, T.5
-
43
-
-
31544455030
-
Triple combination of oncolytic herpes simplex virus-1 vectors armed with interleukin-12, interleukin-18, or soluble B7-1 results in enhanced antitumor efficacy
-
Ino Y, Saeki Y, Fukuhara H, Todo T. Triple combination of oncolytic herpes simplex virus-1 vectors armed with interleukin-12, interleukin-18, or soluble B7-1 results in enhanced antitumor efficacy. Clin. Cancer Res. 12(2), 643-652 (2006
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.2
, pp. 643-652
-
-
Ino, Y.1
Saeki, Y.2
Fukuhara, H.3
Todo, T.4
-
44
-
-
0035138174
-
In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity
-
Todo T, Martuza RL, Dallman MJ, Rabkin SD. In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity. Cancer Res. 61(1), 153-161 (2001
-
(2001)
Cancer Res
, vol.61
, Issue.1
, pp. 153-161
-
-
Todo, T.1
Martuza, R.L.2
Dallman, M.J.3
Rabkin, S.D.4
-
45
-
-
33750332951
-
Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model
-
Lee YS, Kim JH, Choi KJ, et al. Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model. Clin. Cancer Res. 12(19), 5859-5868 (2006
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.19
, pp. 5859-5868
-
-
Lee, Y.S.1
Kim, J.H.2
Choi, K.J.3
-
46
-
-
33745191473
-
Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect
-
Choi KJ, Kim JH, Lee YS, et al. Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect. Gene Ther. 13(13), 1010-1020 (2006
-
(2006)
Gene Ther
, vol.13
, Issue.13
, pp. 1010-1020
-
-
Choi, K.J.1
Kim, J.H.2
Lee, Y.S.3
-
47
-
-
33750704266
-
Different mechanisms for anti-Tumor effects of low-And high-dose cyclophosphamide
-
Motoyoshi Y, Kaminoda K, Saitoh O, et al. Different mechanisms for anti-Tumor effects of low-And high-dose cyclophosphamide. Oncol. Rep. 16(1), 141-146 (2006
-
(2006)
Oncol. Rep
, vol.16
, Issue.1
, pp. 141-146
-
-
Motoyoshi, Y.1
Kaminoda, K.2
Saitoh, O.3
-
48
-
-
80052420081
-
Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus
-
Cerullo V, Diaconu I, Kangasniemi L, et al. Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus. Mol. Ther. 19(9), 1737-1746 (2011
-
(2011)
Mol. Ther
, vol.19
, Issue.9
, pp. 1737-1746
-
-
Cerullo, V.1
Diaconu, I.2
Kangasniemi, L.3
-
49
-
-
68549112974
-
Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model
-
Banissi C, Ghiringhelli F, Chen L, Carpentier AF. Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model. Cancer Immunol. Immunother. 58(10), 1627-1634 (2009
-
(2009)
Cancer Immunol. Immunother
, vol.58
, Issue.10
, pp. 1627-1634
-
-
Banissi, C.1
Ghiringhelli, F.2
Chen, L.3
Carpentier, A.F.4
-
50
-
-
84897476768
-
Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy
-
226ra232
-
Zamarin D, Holmgaard RB, Subudhi SK, et al. Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy. Sci. Transl. Med. 6(226), 226ra232 (2014
-
(2014)
Sci. Transl. Med
, vol.6
, Issue.226
-
-
Zamarin, D.1
Holmgaard, R.B.2
Subudhi, S.K.3
-
51
-
-
84872339660
-
The price of tumor control: An analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network
-
Voskens CJ, Goldinger SM, Loquai C, et al. The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network. PLoS ONE 8(1), e53745 (2013
-
(2013)
PLoS ONE
, vol.8
, Issue.1
, pp. e53745
-
-
Voskens, C.J.1
Goldinger, S.M.2
Loquai, C.3
-
52
-
-
84867397020
-
Targeted cancer immunotherapy with oncolytic adenovirus coding for a fully human monoclonal antibody specific for CTLA-4
-
Dias JD, Hemminki O, Diaconu I, et al Targeted Cancer Immunotherapy with Oncolytic Adenovirus Coding for A Fully Human Monoclonal Antibody Specific for CTLA-4. Gene Ther. 19(10), 988-998 (2012
-
(2012)
Gene Ther
, vol.19
, Issue.10
, pp. 988-998
-
-
Dias, J.D.1
Hemminki, O.2
Diaconu, I.3
-
53
-
-
84964314651
-
CTLA-4 and PD-L1 checkpoint blockade enhances oncolytic measles virus therapy
-
Engeland CE, Grossardt C, Veinalde R, et al. CTLA-4 and PD-L1 checkpoint blockade enhances oncolytic measles virus therapy. Mol. Ther. 22(11), 1949-1959 (2014
-
(2014)
Mol. Ther
, vol.22
, Issue.11
, pp. 1949-1959
-
-
Engeland, C.E.1
Grossardt, C.2
Veinalde, R.3
-
54
-
-
84906307026
-
Tumor-specific oncolytic adenoviruses expressing granulocyte macrophage colonystimulating factor or anti-CTLA4 antibody for the treatment of cancers
-
Du T, Shi G, Li YM, et al. Tumor-specific oncolytic adenoviruses expressing granulocyte macrophage colonystimulating factor or anti-CTLA4 antibody for the treatment of cancers. Cancer Gene Ther. 21(8), 340-348 (2014
-
(2014)
Cancer Gene Ther
, vol.21
, Issue.8
, pp. 340-348
-
-
Du, T.1
Shi, G.2
Li, Y.M.3
-
55
-
-
84927645890
-
Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression
-
Rodríguez-García A, Giménez-Alejandre M, Rojas JJ, et al. Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression. Clin. Cancer Res. 21(6), 1406-1418 (2015
-
(2015)
Clin. Cancer Res
, vol.21
, Issue.6
, pp. 1406-1418
-
-
Rodríguez-García, A.1
Giménez-Alejandre, M.2
Rojas, J.J.3
-
56
-
-
0035887154
-
Combined intratumoral injection of bone marrow-derived dendritic cells and systemic chemotherapy to treat pre-existing murine tumors
-
Tong Y, Song W, Crystal RG. Combined intratumoral injection of bone marrow-derived dendritic cells and systemic chemotherapy to treat pre-existing murine tumors. Cancer Res. 61(20), 7530-7535 (2001
-
(2001)
Cancer Res
, vol.61
, Issue.20
, pp. 7530-7535
-
-
Tong, Y.1
Song, W.2
Crystal, R.G.3
-
57
-
-
21344461909
-
Therapeutic vaccination against murine lymphoma by intratumoral injection of naive dendritic cells
-
Song W, Levy R. Therapeutic vaccination against murine lymphoma by intratumoral injection of naive dendritic cells. Cancer Res. 65(13), 5958-5964 (2005
-
(2005)
Cancer Res
, vol.65
, Issue.13
, pp. 5958-5964
-
-
Song, W.1
Levy, R.2
-
58
-
-
33646394875
-
Systemic antitumor effect of intratumoral injection of dendritic cells in combination with local photodynamic therapy
-
Saji H, Song W, Furumoto K, Kato H, Engleman EG. Systemic antitumor effect of intratumoral injection of dendritic cells in combination with local photodynamic therapy. Clin. Cancer Res. 12(8), 2568-2574 (2006
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.8
, pp. 2568-2574
-
-
Saji, H.1
Song, W.2
Furumoto, K.3
Kato, H.4
Engleman, E.G.5
-
59
-
-
34247363968
-
Intratumoral injection of dendritic cells in combination with local hyperthermia induces systemic antitumor effect in patients with advanced melanoma
-
Guo J, Zhu J, Sheng X, et al. Intratumoral injection of dendritic cells in combination with local hyperthermia induces systemic antitumor effect in patients with advanced melanoma. Int. J. Cancer 120(11), 2418-2425 (2007
-
(2007)
Int. J. Cancer
, vol.120
, Issue.11
, pp. 2418-2425
-
-
Guo, J.1
Zhu, J.2
Sheng, X.3
-
60
-
-
84920564285
-
Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma
-
Kolstad A, Kumari S, Walczak M, et al. Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma. Blood 125(1), 82-89 (2015
-
(2015)
Blood
, vol.125
, Issue.1
, pp. 82-89
-
-
Kolstad, A.1
Kumari, S.2
Walczak, M.3
-
61
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-Tumor immunity
-
Dranoff G, Jaffee E, Lazenby A, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-Tumor immunity. Proc. Natl Acad. Sci. USA 90(8), 3539-3543 (1993
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, Issue.8
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
-
62
-
-
84951728734
-
The therapeutic effect of intratumoral injection of GM-CSF gene-modified allogenic macrophages on tumor-bearing mice
-
Yizhi Y, Xuetao C, Hong L, Quanxing W, Qun T. The therapeutic effect of intratumoral injection of GM-CSF gene-modified allogenic macrophages on tumor-bearing mice. Chin. J. Cancer Res. 10(1), 1-5 (1998
-
(1998)
Chin. J. Cancer Res
, vol.10
, Issue.1
, pp. 1-5
-
-
Yizhi, Y.1
Xuetao, C.2
Hong, L.3
Quanxing, W.4
Qun, T.5
-
63
-
-
0032573225
-
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma
-
Soiffer R, Lynch T, Mihm M, et al. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc. Natl Acad. Sci. USA 95(22), 13141-13146 (1998
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, Issue.22
, pp. 13141-13146
-
-
Soiffer, R.1
Lynch, T.2
Mihm, M.3
-
64
-
-
0034047619
-
Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand
-
Mach N, Gillessen S, Wilson SB, Sheehan C, Mihm M, Dranoff G. Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand. Cancer Res. 60(12), 3239-3246 (2000
-
(2000)
Cancer Res
, vol.60
, Issue.12
, pp. 3239-3246
-
-
Mach, N.1
Gillessen, S.2
Wilson, S.B.3
Sheehan, C.4
Mihm, M.5
Dranoff, G.6
-
65
-
-
0035720479
-
Perilesional injection of r-GM-CSF in patients with cutaneous melanoma metastases
-
Hoeller C, Jansen B, Heere-Ress E, et al. Perilesional injection of r-GM-CSF in patients with cutaneous melanoma metastases. J. Invest. Dermatol. 117(2), 371-374 (2001
-
(2001)
J. Invest. Dermatol
, vol.117
, Issue.2
, pp. 371-374
-
-
Hoeller, C.1
Jansen, B.2
Heere-Ress, E.3
-
66
-
-
33845898737
-
Steady-state and inflammatory dendritic-cell development
-
Shortman K, Naik SH. Steady-state and inflammatory dendritic-cell development. Nat. Rev. Immunol. 7(1), 19-30 (2007
-
(2007)
Nat. Rev. Immunol
, vol.7
, Issue.1
, pp. 19-30
-
-
Shortman, K.1
Naik, S.H.2
-
67
-
-
0036093631
-
Mobilization of dendritic cell precursors in patients with cancer by flt3 ligand allows the generation of higher yields of cultured dendritic cells
-
Marroquin CE, Westwood JA, Lapointe R, et al. Mobilization of dendritic cell precursors in patients with cancer by flt3 ligand allows the generation of higher yields of cultured dendritic cells. J. Immunother. 25(3), 278-288 (2002
-
(2002)
J. Immunother
, vol.25
, Issue.3
, pp. 278-288
-
-
Marroquin, C.E.1
Westwood, J.A.2
Lapointe, R.3
-
68
-
-
0034548854
-
Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer
-
Morse MA, Nair S, Fernandez-Casal M, et al. Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer. J. Clin. Oncol. 18(23), 3883-3893 (2000
-
(2000)
J. Clin. Oncol
, vol.18
, Issue.23
, pp. 3883-3893
-
-
Morse, M.A.1
Nair, S.2
Fernandez-Casal, M.3
-
69
-
-
0035282905
-
In vitro tumor-pulsed or in vivo Flt3 ligandgenerated dendritic cells provide protection against acute myelogenous leukemia in nontransplanted or syngeneic bone marrow-Transplanted mice
-
Pawlowska AB, Hashino S, Mckenna H, Weigel BJ, Taylor PA, Blazar BR. In vitro tumor-pulsed or in vivo Flt3 ligandgenerated dendritic cells provide protection against acute myelogenous leukemia in nontransplanted or syngeneic bone marrow-Transplanted mice. Blood 97(5), 1474-1482 (2001
-
(2001)
Blood 97
, vol.5
, pp. 1474-1482
-
-
Pawlowska, A.B.1
Hashino, S.2
Mckenna, H.3
Weigel, B.J.4
Taylor, P.A.5
Blazar, B.R.6
-
70
-
-
84888414871
-
Fms-like tyrosine kinase 3 receptor ligand (Flt3L)-based vaccination administered with an adenoviral vector prevents tumor growth of colorectal cancer in a BALB/c mouse model
-
Riediger C, Wingender G, Knolle P, Aulmann S, Stremmel W, Encke J. Fms-like tyrosine kinase 3 receptor ligand (Flt3L)-based vaccination administered with an adenoviral vector prevents tumor growth of colorectal cancer in a BALB/c mouse model. J. Cancer Res. Clin. Oncol. 139(12), 2097-2110 (2013
-
(2013)
J. Cancer Res. Clin. Oncol
, vol.139
, Issue.12
, pp. 2097-2110
-
-
Riediger, C.1
Wingender, G.2
Knolle, P.3
Aulmann, S.4
Stremmel, W.5
Encke, J.6
-
71
-
-
34447644973
-
Eradication of hepatoma and colon cancer in mice with Flt3L gene therapy in combination with 5-FU
-
Hou S, Kou G, Fan X, et al. Eradication of hepatoma and colon cancer in mice with Flt3L gene therapy in combination with 5-FU. Cancer Immunol. Immunother. 56(10), 1605-1613 (2007
-
(2007)
Cancer Immunol. Immunother
, vol.56
, Issue.10
, pp. 1605-1613
-
-
Hou, S.1
Kou, G.2
Fan, X.3
-
72
-
-
80053347071
-
FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines
-
Kreiter S, Diken M, Selmi A, et al. FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines. Cancer Res. 71(19), 6132-6142 (2011
-
(2011)
Cancer Res
, vol.71
, Issue.19
, pp. 6132-6142
-
-
Kreiter, S.1
Diken, M.2
Selmi, A.3
-
73
-
-
84951792672
-
Converting tumors into vaccine manufacturing factories: DC recruitment activation and clinical responses with a Flt3L-primed in situ vaccine for low-grade lymphoma [NCT01976585]
-
Bhardwaj N, Merad M, Kim-Schulze S, et al. Converting tumors into vaccine manufacturing factories: DC recruitment, activation and clinical responses with a Flt3L-primed In situ vaccine for low-grade lymphoma [NCT01976585]. J. Immunother. Cancer 2(SUPPL 3), 45 (2014
-
(2014)
J. Immunother. Cancer
, vol.2
, Issue.SUPPL. 3
, pp. 45
-
-
Bhardwaj, N.1
Merad, M.2
Kim-Schulze, S.3
-
74
-
-
0035155134
-
CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens
-
Jahrsdörfer B, Hartmann G, Racila E, et al. CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens. J. Leukoc. Biol. 69(1), 81-88 (2001
-
(2001)
J. Leukoc. Biol
, vol.69
, Issue.1
, pp. 81-88
-
-
Jahrsdörfer, B.1
Hartmann, G.2
Racila, E.3
-
75
-
-
34848856815
-
Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself
-
Li J, Song W, Czerwinski DK, et al. Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself. J. Immunol. 179(4), 2493-2500 (2007
-
(2007)
J. Immunol
, vol.179
, Issue.4
, pp. 2493-2500
-
-
Li, J.1
Song, W.2
Czerwinski, D.K.3
-
76
-
-
59449094095
-
Immunotransplantation preferentially expands T-effector cells over T-regulatory cells and cures large lymphoma tumors
-
Brody JD, Goldstein MJ, Czerwinski DK, Levy R. Immunotransplantation preferentially expands T-effector cells over T-regulatory cells and cures large lymphoma tumors. Blood 113(1), 85-94 (2009
-
(2009)
Blood
, vol.113
, Issue.1
, pp. 85-94
-
-
Brody, J.D.1
Goldstein, M.J.2
Czerwinski, D.K.3
Levy, R.4
-
77
-
-
84878567974
-
Depleting tumorspecific Tregs at a single site eradicates disseminated tumors
-
Marabelle A, Kohrt H, Sagiv-Barfi I, et al. Depleting tumorspecific Tregs at a single site eradicates disseminated tumors. J. Clin. Invest. 123(6), 2447-2463 (2013
-
(2013)
J. Clin. Invest
, vol.123
, Issue.6
, pp. 2447-2463
-
-
Marabelle, A.1
Kohrt, H.2
Sagiv-Barfi, I.3
-
78
-
-
65349153756
-
T-cell modulation combined with intratumoral CpG cures lymphoma in a mouse model without the need for chemotherapy
-
Houot R, Levy R. T-cell modulation combined with intratumoral CpG cures lymphoma in a mouse model without the need for chemotherapy. Blood 113(15), 3546-3552 (2009
-
(2009)
Blood
, vol.113
, Issue.15
, pp. 3546-3552
-
-
Houot, R.1
Levy, R.2
-
79
-
-
78049420571
-
In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: A Phase I/II study
-
Brody JD, Ai WZ, Czerwinski DK, et al. In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: a Phase I/II study. J. Clin. Oncol. 28(28), 4324-4332 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.28
, pp. 4324-4332
-
-
Brody, J.D.1
Ai, W.Z.2
Czerwinski, D.K.3
-
80
-
-
84862907845
-
In situ vaccination against mycosis fungoides by intratumoral injection of a TLR9 agonist combined with radiation: A Phase 1/2 study
-
Kim YH, Gratzinger D, Harrison C, et al. In situ vaccination against mycosis fungoides by intratumoral injection of a TLR9 agonist combined with radiation: a Phase 1/2 study. Blood 119(2), 355-363 (2012
-
(2012)
Blood 119
, vol.2
, pp. 355-363
-
-
Kim, Y.H.1
Gratzinger, D.2
Harrison, C.3
-
81
-
-
58149177780
-
TLR ligands in the local treatment of established intracerebral murine gliomas
-
Grauer OM, Molling JW, Bennink E, et al. TLR ligands in the local treatment of established intracerebral murine gliomas. J. Immunol. 181(10), 6720-6729 (2008
-
(2008)
J. Immunol
, vol.181
, Issue.10
, pp. 6720-6729
-
-
Grauer, O.M.1
Molling, J.W.2
Bennink, E.3
-
82
-
-
68549110522
-
Regression of established AB1 murine mesothelioma induced by peritumoral injections of CpG oligodeoxynucleotide either alone or in combination with poly(I: C) and CD40 ligand plasmid DNA
-
Stone GW, Barzee S, Snarsky V, Santucci C, Tran B, Kornbluth RS. Regression of established AB1 murine mesothelioma induced by peritumoral injections of CpG oligodeoxynucleotide either alone or in combination with poly(I: C) and CD40 ligand plasmid DNA. J. Thorac. Oncol. 4(7), 802-808 (2009
-
(2009)
J. Thorac. Oncol
, vol.4
, Issue.7
, pp. 802-808
-
-
Stone, G.W.1
Barzee, S.2
Snarsky, V.3
Santucci, C.4
Tran, B.5
Kornbluth, R.S.6
-
83
-
-
38649132010
-
CpG-ODN but not other TLR-ligands restore the antitumor responses in old mice: The implications for vaccinations in the aged
-
Sharma S, Dominguez AL, Hoelzinger DB, Lustgarten J. CpG-ODN but not other TLR-ligands restore the antitumor responses in old mice: the implications for vaccinations in the aged. Cancer Immunol. Immunother. 57(4), 549-561 (2008
-
(2008)
Cancer Immunol. Immunother
, vol.57
, Issue.4
, pp. 549-561
-
-
Sharma, S.1
Dominguez, A.L.2
Hoelzinger, D.B.3
Lustgarten, J.4
-
84
-
-
1842486876
-
Induction of potent antitumor immunity by in situ targeting of intratumoral DCs
-
Furumoto K, Soares L, Engleman EG, Merad M. Induction of potent antitumor immunity by In situ targeting of intratumoral DCs. J. Clin. Invest. 113(5), 774-783 (2004
-
(2004)
J. Clin. Invest
, vol.113
, Issue.5
, pp. 774-783
-
-
Furumoto, K.1
Soares, L.2
Engleman, E.G.3
Merad, M.4
-
85
-
-
84861630513
-
An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy
-
Zhang H, Liu L, Yu D, et al. An In situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy. PLoS ONE 7(5), e38111 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.5
, pp. e38111
-
-
Zhang, H.1
Liu, L.2
Yu, D.3
-
86
-
-
0026717120
-
Inhibition of murine tumor growth by an interferon-inducing imidazoquinolinamine
-
Sidky YA, Borden EC, Weeks CE, Reiter MJ, Hatcher JF, Bryan GT. Inhibition of murine tumor growth by an interferon-inducing imidazoquinolinamine. Cancer Res. 52(13), 3528-3533 (1992
-
(1992)
Cancer Res
, vol.52
, Issue.13
, pp. 3528-3533
-
-
Sidky, Y.A.1
Borden, E.C.2
Weeks, C.E.3
Reiter, M.J.4
Hatcher, J.F.5
Bryan, G.T.6
-
87
-
-
84871217036
-
Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer
-
Adams S, Kozhaya L, Martiniuk F, et al. Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer. Clin. Cancer Res. 18(24), 6748-6757 (2012
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.24
, pp. 6748-6757
-
-
Adams, S.1
Kozhaya, L.2
Martiniuk, F.3
-
88
-
-
84899659677
-
Imiquimod in the treatment of breast cancer skin metastasis
-
Henriques L, Palumbo M, Guay MP, et al. Imiquimod in the treatment of breast cancer skin metastasis. J. Clin. Oncol. 32(8), e22-25 (2014
-
(2014)
J. Clin. Oncol
, vol.32
, Issue.8
, pp. e22-25
-
-
Henriques, L.1
Palumbo, M.2
Guay, M.P.3
-
89
-
-
81755184427
-
Treatment of locally recurrent mucosal melanoma with topical imiquimod
-
Smyth EC, Flavin M, Pulitzer MP, et al. Treatment of locally recurrent mucosal melanoma with topical imiquimod. J. Clin. Oncol. 29(33), e809-811 (2011
-
(2011)
J. Clin. Oncol
, vol.29
, Issue.33
, pp. e809-811
-
-
Smyth, E.C.1
Flavin, M.2
Pulitzer, M.P.3
-
90
-
-
84971671379
-
Long-Term remission of primary cutaneous neutrophil-rich CD30+anaplastic large cell lymphoma treated with topical imiquimod
-
Epub ahead of print
-
Calista D, Riccioni L, Bagli L, Valenzano F. Long-Term remission of primary cutaneous neutrophil-rich CD30+anaplastic large cell lymphoma treated with topical imiquimod. A case report. J. Eur. Acad. Dermatol. Venereol. doi: 10.1111/jdv.13070 (2015) (Epub ahead of print
-
(2015)
A Case Report. J. Eur. Acad. Dermatol. Venereol
-
-
Calista, D.1
Riccioni, L.2
Bagli, L.3
Valenzano, F.4
-
91
-
-
3142655707
-
Primary cutaneous CD30+ T-cell lymphoma responsive to topical imiquimod (Aldara
-
Didona B, Benucci R, Amerio P, Canzona F, Rienzo O, Cavalieri R. Primary cutaneous CD30+ T-cell lymphoma responsive to topical imiquimod (Aldara). Br. J. Dermatol. 150(6), 1198-1201 (2004
-
(2004)
Br. J. Dermatol
, vol.150
, Issue.6
, pp. 1198-1201
-
-
Didona, B.1
Benucci, R.2
Amerio, P.3
Canzona, F.4
Rienzo, O.5
Cavalieri, R.6
-
92
-
-
47749088927
-
Primary cutaneous CD30+ anaplastic large cell lymphoma responds to imiquimod cream
-
Ehst BD, Dreno B, Vonderheid EC. Primary cutaneous CD30+ anaplastic large cell lymphoma responds to imiquimod cream. Eur. J. Dermatol. 18(4), 467-468 (2008
-
(2008)
Eur. J. Dermatol
, vol.18
, Issue.4
, pp. 467-468
-
-
Ehst, B.D.1
Dreno, B.2
Vonderheid, E.C.3
-
93
-
-
33749872730
-
Treatment of mycosis fungoides with imiquimod 5% cream
-
Ariffin N, Khorshid M. Treatment of mycosis fungoides with imiquimod 5% cream. Clin. Exp. Dermatol. 31(6), 822-823 (2006
-
(2006)
Clin. Exp. Dermatol
, vol.31
, Issue.6
, pp. 822-823
-
-
Ariffin, N.1
Khorshid, M.2
-
94
-
-
0141561484
-
Imiquimod induces complete clearance of a PUVA-resistant plaque in mycosis fungoides
-
Dummer R, Urosevic M, Kempf W, Kazakov D, Burg G. Imiquimod induces complete clearance of a PUVA-resistant plaque in mycosis fungoides. Dermatology 207(1), 116-118 (2003
-
(2003)
Dermatology
, vol.207
, Issue.1
, pp. 116-118
-
-
Dummer, R.1
Urosevic, M.2
Kempf, W.3
Kazakov, D.4
Burg, G.5
-
95
-
-
0036718001
-
Treatment of stage IA cutaneous T-cell lymphoma with topical application of the immune response modifier imiquimod
-
Suchin KR, Junkins-Hopkins JM, Rook AH. Treatment of stage IA cutaneous T-cell lymphoma with topical application of the immune response modifier imiquimod. Arch. Dermatol. 138(9), 1137-1139 (2002
-
(2002)
Arch. Dermatol
, vol.138
, Issue.9
, pp. 1137-1139
-
-
Suchin, K.R.1
Junkins-Hopkins, J.M.2
Rook, A.H.3
-
96
-
-
1842713105
-
Imiquimod 5% cream in the treatment of mycosis fungoides-A pilot study
-
Chong A, Loo WJ, Banney L, Grant JW, Norris PG. Imiquimod 5% cream in the treatment of mycosis fungoides-A pilot study. J. Dermatolog. Treat. 15(2), 118-119 (2004
-
(2004)
J. Dermatolog. Treat
, vol.15
, Issue.2
, pp. 118-119
-
-
Chong, A.1
Loo, W.J.2
Banney, L.3
Grant, J.W.4
Norris, P.G.5
-
97
-
-
23044438781
-
Treatment of patch and plaque stage mycosis fungoides with imiquimod 5% cream
-
Deeths MJ, Chapman JT, Dellavalle RP, Zeng C, Aeling JL. Treatment of patch and plaque stage mycosis fungoides with imiquimod 5% cream. J. Am. Acad. Dermatol. 52(2), 275-280 (2005
-
(2005)
J. Am. Acad. Dermatol
, vol.52
, Issue.2
, pp. 275-280
-
-
Deeths, M.J.1
Chapman, J.T.2
Dellavalle, R.P.3
Zeng, C.4
Aeling, J.L.5
-
98
-
-
33748327012
-
Unilesional mycosis fungoides successfully treated with imiquimod
-
Ardigo M, Cota C, Berardesca E. Unilesional mycosis fungoides successfully treated with imiquimod. Eur. J. Dermatol. 16(4), 446 (2006
-
(2006)
Eur. J. Dermatol
, vol.16
, Issue.4
, pp. 446
-
-
Ardigo, M.1
Cota, C.2
Berardesca, E.3
-
99
-
-
44649124290
-
Primary cutaneous follicle center lymphoma associated with alopecia areata
-
Richmond HM, Lozano A, Jones D, Duvic M. Primary cutaneous follicle center lymphoma associated with alopecia areata. Clin. Lymphoma Myeloma 8(2), 121-124 (2008
-
(2008)
Clin. Lymphoma Myeloma
, vol.8
, Issue.2
, pp. 121-124
-
-
Richmond, H.M.1
Lozano, A.2
Jones, D.3
Duvic, M.4
-
100
-
-
34547871653
-
Successful treatment of primary cutaneous follicle centre lymphoma with topical 5% imiquimod
-
Stavrakoglou A, Brown VL, Coutts I. Successful treatment of primary cutaneous follicle centre lymphoma with topical 5% imiquimod. Br. J. Dermatol. 157(3), 620-622 (2007
-
(2007)
Br. J. Dermatol
, vol.157
, Issue.3
, pp. 620-622
-
-
Stavrakoglou, A.1
Brown, V.L.2
Coutts, I.3
-
101
-
-
33748334284
-
Topical imiquimod as treatment for different kinds of cutaneous lymphoma
-
Coors EA, Schuler G, Von Den Driesch P. Topical imiquimod as treatment for different kinds of cutaneous lymphoma. Eur. J. Dermatol. 16(4), 391-393 (2006
-
(2006)
Eur. J. Dermatol
, vol.16
, Issue.4
, pp. 391-393
-
-
Coors, E.A.1
Schuler, G.2
Von Den Driesch, P.3
-
102
-
-
21844442818
-
Regression of lymphomatous skin deposits in a chronic lymphocytic leukemia patient treated with the Toll-like receptor-7/8 agonist, imiquimod
-
Spaner DE, Miller RL, Mena J, Grossman L, Sorrenti V, Shi Y. Regression of lymphomatous skin deposits in a chronic lymphocytic leukemia patient treated with the Toll-like receptor-7/8 agonist, imiquimod. Leuk. Lymphoma 46(6), 935-939 (2005
-
(2005)
Leuk. Lymphoma
, vol.46
, Issue.6
, pp. 935-939
-
-
Spaner, D.E.1
Miller, R.L.2
Mena, J.3
Grossman, L.4
Sorrenti, V.5
Shi, Y.6
-
103
-
-
84871230007
-
Synergy of topical Toll-like receptor 7 agonist with radiation and low-dose cyclophosphamide in a mouse model of cutaneous breast cancer
-
Dewan MZ, Vanpouille-Box C, Kawashima N, et al. Synergy of topical Toll-like receptor 7 agonist with radiation and low-dose cyclophosphamide in a mouse model of cutaneous breast cancer. Clin. Cancer Res. 18(24), 6668-6678 (2012
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.24
, pp. 6668-6678
-
-
Dewan, M.Z.1
Vanpouille-Box, C.2
Kawashima, N.3
-
104
-
-
84872328340
-
Systemic delivery of a TLR7 agonist in combination with radiation primes durable antitumor immune responses in mouse models of lymphoma
-
Dovedi SJ, Melis MH, Wilkinson RW, et al. Systemic delivery of a TLR7 agonist in combination with radiation primes durable antitumor immune responses in mouse models of lymphoma. Blood 121(2), 251-259 (2013
-
(2013)
Blood
, vol.121
, Issue.2
, pp. 251-259
-
-
Dovedi, S.J.1
Melis, M.H.2
Wilkinson, R.W.3
-
105
-
-
84908147322
-
Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation
-
Singh M, Khong H, Dai Z, et al. Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation. J. Immunol. 193(9), 4722-4731 (2014
-
(2014)
J. Immunol
, vol.193
, Issue.9
, pp. 4722-4731
-
-
Singh, M.1
Khong, H.2
Dai, Z.3
-
106
-
-
33744791510
-
Essential role of MDA-5 in type i IFN responses to polyriboinosinic: Polyribocytid ylic acid and encephalomyocarditis picornavirus
-
Gitlin L, Barchet W, Gilfillan S, et al. Essential role of MDA-5 in type I IFN responses to polyriboinosinic: polyribocytid ylic acid and encephalomyocarditis picornavirus. Proc. Natl Acad. Sci. USA 103(22), 8459-8464 (2006
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.22
, pp. 8459-8464
-
-
Gitlin, L.1
Barchet, W.2
Gilfillan, S.3
-
107
-
-
17844384773
-
Defining the antigen-specific T-cell response to vaccination and poly(I: C)/TLR3 signaling: Evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity
-
Salem ML, Kadima AN, Cole DJ, Gillanders WE. Defining the antigen-specific T-cell response to vaccination and poly(I: C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity. J. Immunother. 28(3), 220-228 (2005
-
(2005)
J. Immunother
, vol.28
, Issue.3
, pp. 220-228
-
-
Salem, M.L.1
Kadima, A.N.2
Cole, D.J.3
Gillanders, W.E.4
-
108
-
-
33744521498
-
The adjuvant effects of the Toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I: C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu
-
Salem ML, El-Naggar SA, Kadima A, Gillanders WE, Cole DJ. The adjuvant effects of the Toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I: C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu. Vaccine 24(24), 5119-5132 (2006
-
(2006)
Vaccine
, vol.24
, Issue.24
, pp. 5119-5132
-
-
Salem, M.L.1
El-Naggar, S.A.2
Kadima, A.3
Gillanders, W.E.4
Cole, D.J.5
-
109
-
-
33847674371
-
Toll-like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models
-
Zhu X, Nishimura F, Sasaki K, et al. Toll-like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models. J. Transl. Med. 5, 10 (2007
-
(2007)
J. Transl. Med
, vol.5
, pp. 10
-
-
Zhu, X.1
Nishimura, F.2
Sasaki, K.3
-
110
-
-
77955515616
-
Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-Alpha and IFNgamma dependent manners
-
Zhu X, Fallert-Junecko BA, Fujita M, et al. Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-Alpha and IFNgamma dependent manners. Cancer Immunol. Immunother. 59(9), 1401-1409 (2010
-
(2010)
Cancer Immunol. Immunother
, vol.59
, Issue.9
, pp. 1401-1409
-
-
Zhu, X.1
Fallert-Junecko, B.A.2
Fujita, M.3
-
111
-
-
78650138274
-
A multi-institution Phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma
-
Rosenfeld MR, Chamberlain MC, Grossman SA, et al. A multi-institution Phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma. Neuro. Oncol. 12(10), 1071-1077 (2010
-
(2010)
Neuro. Oncol
, vol.12
, Issue.10
, pp. 1071-1077
-
-
Rosenfeld, M.R.1
Chamberlain, M.C.2
Grossman, S.A.3
-
112
-
-
78549282469
-
Improving therapeutic HPV peptide-based vaccine potency by enhancing CD4+ T help and dendritic cell activation
-
Wu CY, Monie A, Pang X, Hung CF, Wu TC. Improving therapeutic HPV peptide-based vaccine potency by enhancing CD4+ T help and dendritic cell activation. J. Biomed. Sci. 17, 88 (2010
-
(2010)
J. Biomed. Sci
, vol.17
, pp. 88
-
-
Wu, C.Y.1
Monie, A.2
Pang, X.3
Hung, C.F.4
Wu, T.C.5
-
113
-
-
79955533553
-
Adoptive immunotherapy combined with intratumoral TLR agonist delivery eradicates established melanoma in mice
-
Amos SM, Pegram HJ, Westwood JA, et al. Adoptive immunotherapy combined with intratumoral TLR agonist delivery eradicates established melanoma in mice. Cancer Immunol. Immunother. 60(5), 671-683 (2011
-
(2011)
Cancer Immunol. Immunother
, vol.60
, Issue.5
, pp. 671-683
-
-
Amos, S.M.1
Pegram, H.J.2
Westwood, J.A.3
-
114
-
-
33845568917
-
Inhibitory effect of the polyinosinic-polycytidylic acid/cationic liposome on the progression of murine B16F10 melanoma
-
Fujimura T, Nakagawa S, Ohtani T, Ito Y, Aiba S. Inhibitory effect of the polyinosinic-polycytidylic acid/cationic liposome on the progression of murine B16F10 melanoma. Eur. J. Immunol. 36(12), 3371-3380 (2006
-
(2006)
Eur. J. Immunol
, vol.36
, Issue.12
, pp. 3371-3380
-
-
Fujimura, T.1
Nakagawa, S.2
Ohtani, T.3
Ito, Y.4
Aiba, S.5
-
115
-
-
70350225364
-
Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-like receptor agonists as a treatment for melanoma
-
Stone GW, Barzee S, Snarsky V, et al. Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-like receptor agonists as a treatment for melanoma. PLoS ONE 4(10), e7334 (2009
-
(2009)
PLoS ONE
, vol.4
, Issue.10
, pp. e7334
-
-
Stone, G.W.1
Barzee, S.2
Snarsky, V.3
-
116
-
-
84923089650
-
Therapeutic in situ autovaccination against solid cancers with intratumoral poly-ICLC: Case report, hypo
-
thesis, and clinical trial
-
Salazar AM, Erlich RB, Mark A, Bhardwaj N, Herberman RB. Therapeutic in situ autovaccination against solid cancers with intratumoral poly-ICLC: case report, hypothesis, and clinical trial. Cancer Immunol. Res. 2(8), 720-724 (2014
-
(2014)
Cancer Immunol. Res
, vol.2
, Issue.8
, pp. 720-724
-
-
Salazar, A.M.1
Erlich, R.B.2
Mark, A.3
Bhardwaj, N.4
Herberman, R.B.5
-
117
-
-
43049179999
-
LPS/TLR4 signal transduction pathway
-
Lu YC, Yeh WC, Ohashi PS. LPS/TLR4 signal transduction pathway. Cytokine 42(2), 145-151 (2008
-
(2008)
Cytokine
, vol.42
, Issue.2
, pp. 145-151
-
-
Lu, Y.C.1
Yeh, W.C.2
Ohashi, P.S.3
-
118
-
-
33645734929
-
Toll-dependent selection of microbial antigens for presentation by dendritic cells
-
Blander JM, Medzhitov R. Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 440(7085), 808-812 (2006
-
(2006)
Nature
, vol.440
, Issue.7085
, pp. 808-812
-
-
Blander, J.M.1
Medzhitov, R.2
-
119
-
-
0018216510
-
The immunological basis of endotoxin-induced tumor regression Requirement for T-cell-mediated immunity
-
Berendt MJ, North RJ, Kirstein DP. The immunological basis of endotoxin-induced tumor regression. Requirement for T-cell-mediated immunity. J. Exp. Med. 148(6), 1550-1559 (1978
-
(1978)
J. Exp. Med
, vol.148
, Issue.6
, pp. 1550-1559
-
-
Berendt, M.J.1
North, R.J.2
Kirstein, D.P.3
-
120
-
-
0025185274
-
Biological response to intravenously administered endotoxin in patients with advanced cancer
-
Engelhardt R, Mackensen A, Galanos C, Andreesen R. Biological response to intravenously administered endotoxin in patients with advanced cancer. J. Biol. Response Mod. 9(5), 480-491 (1990
-
(1990)
J. Biol. Response Mod
, vol.9
, Issue.5
, pp. 480-491
-
-
Engelhardt, R.1
Mackensen, A.2
Galanos, C.3
Andreesen, R.4
-
121
-
-
0035098241
-
Intratumoral injection of lipopolysaccharide causes regression of subcutaneously implanted mouse glioblastoma multiforme
-
607-614; discussion
-
Chicoine MR, Won EK, Zahner MC. Intratumoral injection of lipopolysaccharide causes regression of subcutaneously implanted mouse glioblastoma multiforme. Neurosurgery 48(3), 607-614; discussion 614-605 (2001
-
(2001)
Neurosurgery
, vol.48
, Issue.3
, pp. 614-605
-
-
Chicoine, M.R.1
Won, E.K.2
Zahner, M.C.3
-
122
-
-
0042126772
-
Analysis of the antitumoral mechanisms of lipopolysaccharide against glioblastoma multiforme
-
Won EK, Zahner MC, Grant EA, Gore P, Chicoine MR. Analysis of the antitumoral mechanisms of lipopolysaccharide against glioblastoma multiforme. Anticancer Drugs 14(6), 457-466 (2003
-
(2003)
Anticancer Drugs
, vol.14
, Issue.6
, pp. 457-466
-
-
Won, E.K.1
Zahner, M.C.2
Grant, E.A.3
Gore, P.4
Chicoine, M.R.5
-
123
-
-
36348942901
-
Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GM-CSF leads to an effective anti-Tumor response in subcutaneous RG-2 gliomas
-
Mariani CL, Rajon D, Bova FJ, Streit WJ. Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GM-CSF leads to an effective anti-Tumor response in subcutaneous RG-2 gliomas. J. Neurooncol. 85(3), 231-240 (2007
-
(2007)
J. Neurooncol
, vol.85
, Issue.3
, pp. 231-240
-
-
Mariani, C.L.1
Rajon, D.2
Bova, F.J.3
Streit, W.J.4
-
124
-
-
84944781682
-
Intratumoral TLR-4 agonist injection is critical for modulation of tumor microenvironment and tumor rejection
-
Maito FLDM, Souza APDD, Pereira L, et al. Intratumoral TLR-4 agonist injection is critical for modulation of tumor microenvironment and tumor rejection. ISRN Immunol. 2012, 926817 (2012
-
(2012)
ISRN Immunol
, vol.2012
, pp. 926817
-
-
Maito, F.L.D.M.1
Souza, A.P.D.D.2
Pereira, L.3
-
125
-
-
79959255984
-
Intratumoral administration of TLR4 agonist absorbed into a cellular vector improves antitumor responses
-
Davis MB, Vasquez-Dunddel D, Fu J, Albesiano E, Pardoll D, Kim YJ. Intratumoral administration of TLR4 agonist absorbed into a cellular vector improves antitumor responses. Clin. Cancer Res. 17(12), 3984-3992 (2011
-
(2011)
Clin. Cancer Res
, vol.17
, Issue.12
, pp. 3984-3992
-
-
Davis, M.B.1
Vasquez-Dunddel, D.2
Fu, J.3
Albesiano, E.4
Pardoll, D.5
Kim, Y.J.6
-
126
-
-
0027239503
-
Antitumor and antimetastatic activity of interleukin 12 against murine tumors
-
Brunda MJ, Luistro L, Warrier RR, et al. Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J. Exp. Med. 178(4), 1223-1230 (1993
-
(1993)
J. Exp. Med
, vol.178
, Issue.4
, pp. 1223-1230
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
-
127
-
-
0030766971
-
Effects of singledose interleukin-12 exposure on interleukin-12-Associated toxicity and interferon-gamma production
-
Leonard JP, Sherman ML, Fisher GL, et al. Effects of singledose interleukin-12 exposure on interleukin-12-Associated toxicity and interferon-gamma production. Blood 90(7), 2541-2548 (1997
-
(1997)
Blood
, vol.90
, Issue.7
, pp. 2541-2548
-
-
Leonard, J.P.1
Sherman, M.L.2
Fisher, G.L.3
-
128
-
-
2342570309
-
Phase i trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors
-
Sangro B, Mazzolini G, Ruiz J, et al. Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors. J. Clin. Oncol. 22(8), 1389-1397 (2004
-
(2004)
J. Clin. Oncol
, vol.22
, Issue.8
, pp. 1389-1397
-
-
Sangro, B.1
Mazzolini, G.2
Ruiz, J.3
-
129
-
-
34447514483
-
Intratumoral injection of IL-12 plasmid DNA-Results of a Phase I/IB clinical trial
-
Mahvi DM, Henry MB, Albertini MR, et al. Intratumoral injection of IL-12 plasmid DNA-results of a Phase I/IB clinical trial. Cancer Gene Ther. 14(8), 717-723 (2007
-
(2007)
Cancer Gene Ther
, vol.14
, Issue.8
, pp. 717-723
-
-
Mahvi, D.M.1
Henry, M.B.2
Albertini, M.R.3
-
130
-
-
84872788695
-
Synergistic antitumor effect of JAWSII dendritic cells and interleukin 12 in a melanoma mouse model
-
ZapaLa L, Wolny R, Wachowska M, Jakóbisiak M, Lasek W. Synergistic antitumor effect of JAWSII dendritic cells and interleukin 12 in a melanoma mouse model. Oncol. Rep. 29(3), 1208-1214 (2013
-
(2013)
Oncol. Rep
, vol.29
, Issue.3
, pp. 1208-1214
-
-
ZapaLa, L.1
Wolny, R.2
Wachowska, M.3
Jakóbisiak, M.4
Lasek, W.5
-
131
-
-
0034660885
-
In situ tumor vaccination with interleukin-12-encapsulated biodegradable microspheres: Induction of tumor regression and potent antitumor immunity
-
Egilmez NK, Jong YS, Sabel MS, Jacob JS, Mathiowitz E, Bankert RB. In situ tumor vaccination with interleukin-12-encapsulated biodegradable microspheres: induction of tumor regression and potent antitumor immunity. Cancer Res. 60(14), 3832-3837 (2000
-
(2000)
Cancer Res
, vol.60
, Issue.14
, pp. 3832-3837
-
-
Egilmez, N.K.1
Jong, Y.S.2
Sabel, M.S.3
Jacob, J.S.4
Mathiowitz, E.5
Bankert, R.B.6
-
132
-
-
84890846323
-
Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection
-
Vom Berg J, Vrohlings M, Haller S, et al. Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection. J. Exp. Med. 210(13), 2803-2811 (2013
-
(2013)
J. Exp. Med
, vol.210
, Issue.13
, pp. 2803-2811
-
-
Vom Berg, J.1
Vrohlings, M.2
Haller, S.3
-
133
-
-
0242580050
-
IL-2 intratumoral immunotherapy enhances CD8+ T cells that mediate destruction of tumor cells and tumor-Associated vasculature: A novel mechanism for IL-2
-
Jackaman C, Bundell CS, Kinnear BF, et al. IL-2 intratumoral immunotherapy enhances CD8+ T cells that mediate destruction of tumor cells and tumor-Associated vasculature: a novel mechanism for IL-2. J. Immunol. 171(10), 5051-5063 (2003
-
(2003)
J Immunol
, vol.171
, Issue.10
, pp. 5051-5063
-
-
Jackaman, C.1
Bundell, C.S.2
Kinnear, B.F.3
-
134
-
-
0034918278
-
Immunotherapy of established tumors in mice by intratumoral injection of an adenovirus vector harboring the human IL-2 cDNA: Induction of CD8(+) T-cell immunity and NK activity
-
Slos P, De Meyer M, Leroy P, Rousseau C, Acres B. Immunotherapy of established tumors in mice by intratumoral injection of an adenovirus vector harboring the human IL-2 cDNA: induction of CD8(+) T-cell immunity and NK activity. Cancer Gene Ther. 8(5), 321-332 (2001
-
(2001)
Cancer Gene Ther
, vol.8
, Issue.5
, pp. 321-332
-
-
Slos, P.1
De Meyer, M.2
Leroy, P.3
Rousseau, C.4
Acres, B.5
-
135
-
-
0035931043
-
In situ vaccination against a non-immunogenic tumour using intratumoural injections of liposomal interleukin 2
-
Neville ME, Robb RJ, Popescu MC. In situ vaccination against a non-immunogenic tumour using intratumoural injections of liposomal interleukin 2. Cytokine 16(6), 239-250 (2001
-
(2001)
Cytokine
, vol.16
, Issue.6
, pp. 239-250
-
-
Neville, M.E.1
Robb, R.J.2
Popescu, M.C.3
-
136
-
-
20444486151
-
Microwave tumour coagulation plus in situ treatment with cytokinemicroparticles: Induction of potent anti-residual tumour immunity
-
Kuang M, Liu SQ, Saijo K, et al. Microwave tumour coagulation plus In situ treatment with cytokinemicroparticles: induction of potent anti-residual tumour immunity. Int. J. Hyperthermia 21(3), 247-257 (2005
-
(2005)
Int. J. Hyperthermia
, vol.21
, Issue.3
, pp. 247-257
-
-
Kuang, M.1
Liu, S.Q.2
Saijo, K.3
-
137
-
-
0034169383
-
Intratumoral interleukin 2 for renal-cell carcinoma by direct gene transfer of a plasmid DNA/DMRIE/DOPE lipid complex
-
Hoffman DM, Figlin RA. Intratumoral interleukin 2 for renal-cell carcinoma by direct gene transfer of a plasmid DNA/DMRIE/DOPE lipid complex. World J. Urol. 18(2), 152-156 (2000
-
(2000)
World J. Urol
, vol.18
, Issue.2
, pp. 152-156
-
-
Hoffman, D.M.1
Figlin, R.A.2
-
138
-
-
0344440995
-
Phase II trial of intralesional therapy with interleukin-2 in soft-Tissue melanoma metastases
-
Radny P, Caroli UM, Bauer J, et al. Phase II trial of intralesional therapy with interleukin-2 in soft-Tissue melanoma metastases. Br. J. Cancer 89(9), 1620-1626 (2003
-
(2003)
Br. J. Cancer
, vol.89
, Issue.9
, pp. 1620-1626
-
-
Radny, P.1
Caroli, U.M.2
Bauer, J.3
-
139
-
-
77956831106
-
High response rate after intratumoral treatment with interleukin-2: Results from a phase 2 study in 51 patients with metastasized melanoma
-
Weide B, Derhovanessian E, Pflugfelder A, et al. High response rate after intratumoral treatment with interleukin-2: results from a phase 2 study in 51 patients with metastasized melanoma. Cancer 116(17), 4139-4146 (2010
-
(2010)
Cancer
, vol.116
, Issue.17
, pp. 4139-4146
-
-
Weide, B.1
Derhovanessian, E.2
Pflugfelder, A.3
-
140
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'day SJ, Mcdermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363(8), 711-723 (2010
-
(2010)
N. Engl. J. Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
Mcdermott, D.F.3
-
141
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364(26), 2517-2526 (2011
-
(2011)
N. Engl. J. Med
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
142
-
-
34250871751
-
Combination of tumor sitelocated CTL-Associated antigen-4 blockade and systemic regulatory T-cell depletion induces tumor-destructive immune responses
-
Tuve S, Chen BM, Liu Y, et al. Combination of tumor sitelocated CTL-Associated antigen-4 blockade and systemic regulatory T-cell depletion induces tumor-destructive immune responses. Cancer Res. 67(12), 5929-5939 (2007
-
(2007)
Cancer Res
, vol.67
, Issue.12
, pp. 5929-5939
-
-
Tuve, S.1
Chen, B.M.2
Liu, Y.3
-
143
-
-
44249090471
-
Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity
-
Simmons AD, Moskalenko M, Creson J, et al. Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity. Cancer Immunol. Immunother. 57(8), 1263-1270 (2008
-
(2008)
Cancer Immunol. Immunother
, vol.57
, Issue.8
, pp. 1263-1270
-
-
Simmons, A.D.1
Moskalenko, M.2
Creson, J.3
-
144
-
-
84886427186
-
Controlled local delivery of CTLA-4 blocking antibody induces CD8+ T-cell-dependent tumor eradication and decreases risk of toxic side effects
-
Fransen MF, Van Der Sluis TC, Ossendorp F, Arens R, Melief CJ. Controlled local delivery of CTLA-4 blocking antibody induces CD8+ T-cell-dependent tumor eradication and decreases risk of toxic side effects. Clin. Cancer Res. 19(19), 5381-5389 (2013
-
(2013)
Clin. Cancer Res
, vol.19
, Issue.19
, pp. 5381-5389
-
-
Fransen, M.F.1
Van Der Sluis, T.C.2
Ossendorp, F.3
Arens, R.4
Melief, C.J.5
-
145
-
-
59449108329
-
Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunological responses in indolent B cell lymphoma patients with relapsed and measurable disease: A pilot study
-
Di Nicola M, Zappasodi R, Carlostella C, et al. Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunological responses in indolent B cell lymphoma patients with relapsed and measurable disease: a pilot study. Blood 113(1), 18-27 (2008
-
(2008)
Blood
, vol.113
, Issue.1
, pp. 18-27
-
-
Di Nicola, M.1
Zappasodi, R.2
Carlostella, C.3
-
146
-
-
0036493712
-
Idiotypepulsed dendritic cell vaccination for B-cell lymphoma: Clinical and immune responses in 35 patients
-
Timmerman JM, Czerwinski DK, Davis TA, et al. Idiotypepulsed dendritic cell vaccination for B-cell lymphoma: clinical and immune responses in 35 patients. Blood 99(5), 1517-1526 (2002
-
(2002)
Blood
, vol.99
, Issue.5
, pp. 1517-1526
-
-
Timmerman, J.M.1
Czerwinski, D.K.2
Davis, T.A.3
-
147
-
-
79958264390
-
Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma
-
Schuster SJ, Neelapu SS, Gause BL, et al. Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma. J. Clin. Oncol. 29(20), 2787-2794 (2011
-
(2011)
J. Clin. Oncol
, vol.29
, Issue.20
, pp. 2787-2794
-
-
Schuster, S.J.1
Neelapu, S.S.2
Gause, B.L.3
-
148
-
-
0026793994
-
Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors
-
Kwak LW, Campbell MJ, Czerwinski DK, Hart S, Miller RA, Levy R. Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors. N. Engl. J. Med. 327(17), 1209-1215 (1992
-
(1992)
N. Engl. J. Med
, vol.327
, Issue.17
, pp. 1209-1215
-
-
Kwak, L.W.1
Campbell, M.J.2
Czerwinski, D.K.3
Hart, S.4
Miller, R.A.5
Levy, R.6
-
149
-
-
0032828653
-
Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma
-
Bendandi M, Gocke CD, Kobrin CB, et al. Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma. Nat. Med. 5(10), 1171-1177 (1999
-
(1999)
Nat. Med
, vol.5
, Issue.10
, pp. 1171-1177
-
-
Bendandi, M.1
Gocke, C.D.2
Kobrin, C.B.3
-
150
-
-
33749005382
-
Clinical benefit associated with idiotypic vaccination in patients with follicular lymphoma
-
Inoges S, Rodriguez-Calvillo M, Zabalegui N, et al. Clinical benefit associated with idiotypic vaccination in patients with follicular lymphoma. J. Natl Cancer Inst. 98(18), 1292-1301 (2006
-
(2006)
J. Natl Cancer Inst
, vol.98
, Issue.18
, pp. 1292-1301
-
-
Inoges, S.1
Rodriguez-Calvillo, M.2
Zabalegui, N.3
-
151
-
-
69249104916
-
Idiotype vaccines for lymphoma: Proof-ofprinciples and clinical trial failures
-
Bendandi M. Idiotype vaccines for lymphoma: proof-ofprinciples and clinical trial failures. Nat. Rev. Cancer 9(9), 675-681 (2009
-
(2009)
Nat. Rev. Cancer
, vol.9
, Issue.9
, pp. 675-681
-
-
Bendandi, M.1
-
152
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
Tumeh PC, Harview CL, Yearley JH, et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 515(7528), 568-571 (2014
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 568-571
-
-
Tumeh, P.C.1
Harview, C.L.2
Yearley, J.H.3
-
153
-
-
84928774156
-
The future of immune checkpoint therapy
-
Sharma P, Allison JP. The future of immune checkpoint therapy. Science 348(6230), 56-61 (2015
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 56-61
-
-
Sharma, P.1
Allison, J.P.2
|