Nanoparticle-delivered multimeric soluble CD40L DNA combined with toll-like receptor agonists as a treatment for melanoma

PLoS ONE

Volumn 4, Issue 10, 2009, Pages

  Stone, Geoffrey W ^a,b,e   Barzee, Suzanne ^a,b   Snarsky, Victoria ^a,b   Santucci, Camila ^a,b   Tran, Brian ^a,b   Langer, Robert ^c,d   Zugates, Gregory T ^c   Anderson, Daniel G ^c   Kornbluth, Richard S ^a,b,f  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

^e UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^f BIOTHERAPEUTICS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AVREND; CD40 LIGAND; GLYCOPROTEIN P 15095; IMIQUIMOD; MACROPHAGE ACTIVATING LIPOPEPTIDE 2; NANOPARTICLE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; PHOSPHORYL LIPID A; PLASMID DNA; POLY B AMINO ESTER DERIVATIVE; POLYETHYLENEIMINE; POLYINOSINIC POLYCYTIDYLIC ACID; POLYMER; PROTEIN FSL 1; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG; DNA; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; DRUG POTENTIATION; FEMALE; GENE DELIVERY SYSTEM; GENE EXPRESSION; MELANOMA; MONOTHERAPY; MOUSE; NONHUMAN; ANIMAL; C57BL MOUSE; CANCER TRANSPLANTATION; CHEMISTRY; DRUG DELIVERY SYSTEM; ESCHERICHIA COLI; EXPERIMENTAL MELANOMA; GENETICS; IMMUNOTHERAPY; METABOLISM; METHODOLOGY; PLASMID;

MUS;

ANIMALS; CD40 LIGAND; DNA; DRUG DELIVERY SYSTEMS; ESCHERICHIA COLI; FEMALE; IMMUNOTHERAPY; MELANOMA; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NANOPARTICLES; NEOPLASM TRANSPLANTATION; PLASMIDS; TOLL-LIKE RECEPTORS;

EID: 70350225364     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007334     Document Type: Article

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