-
1
-
-
84875225339
-
Randomized dosefinding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
-
Heo J, Reid T, Ruo L, Breitbach CJ, Rose S, Bloomston M et al. Randomized dosefinding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer. Nat Med 2013; 19: 329-336.
-
(2013)
Nat Med
, vol.19
, pp. 329-336
-
-
Heo, J.1
Reid, T.2
Ruo, L.3
Breitbach, C.J.4
Rose, S.5
Bloomston, M.6
-
2
-
-
74549180404
-
Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers
-
Oberg D, Yanover E, Adam V, Sweeney K, Costas C, Lemoine NR et al. Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers. Clin Cancer Res 2010; 16: 541-553.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 541-553
-
-
Oberg, D.1
Yanover, E.2
Adam, V.3
Sweeney, K.4
Costas, C.5
Lemoine, N.R.6
-
3
-
-
57649125119
-
An oncolytic adenovirus expressing granulocyte macrophage colony-stimulating factor shows improved specificity and efficacy for treating human solid tumors
-
Lei N, Shen FB, Chang JH, Wang L, Li H, Yang C et al. An oncolytic adenovirus expressing granulocyte macrophage colony-stimulating factor shows improved specificity and efficacy for treating human solid tumors. Cancer Gene Ther 2009; 16: 33-43.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 33-43
-
-
Lei, N.1
Shen, F.B.2
Chang, J.H.3
Wang, L.4
Li, H.5
Yang, C.6
-
4
-
-
0033782862
-
An adenovirus E1A mutant that demonstrates potent and selective systemic antitumoral efficacy
-
Heise C, Hermiston T, Johnson L, Brooks G, Sampson-Johannes A, Williams A et al. An adenovirus E1A mutant that demonstrates potent and selective systemic antitumoral efficacy. Nat Med 2000; 6: 1134-1139.
-
(2000)
Nat Med
, vol.6
, pp. 1134-1139
-
-
Heise, C.1
Hermiston, T.2
Johnson, L.3
Brooks, G.4
Sampson-Johannes, A.5
Williams, A.6
-
5
-
-
77953160443
-
Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients
-
Cerullo V, Pesonen S, Diaconu I, Escutenaire S, Arstila PT, Ugolini M et al. Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients. Cancer Res 2010; 70: 4297-4309.
-
(2010)
Cancer Res
, vol.70
, pp. 4297-4309
-
-
Cerullo, V.1
Pesonen, S.2
Diaconu, I.3
Escutenaire, S.4
Arstila, P.T.5
Ugolini, M.6
-
6
-
-
84859376777
-
Oncolytic immunotherapy of advanced solid tumors with a CD40L-expressing replicating adenovirus: Assessment of safety and immunologic responses in patients
-
Pesonen S, Diaconu I, Kangasniemi L, Ranki T, Kanerva A, Pesonen SK et al. Oncolytic immunotherapy of advanced solid tumors with a CD40L-expressing replicating adenovirus: assessment of safety and immunologic responses in patients. Cancer Res 2010; 72: 1621-1631.
-
(2010)
Cancer Res
, vol.72
, pp. 1621-1631
-
-
Pesonen, S.1
Diaconu, I.2
Kangasniemi, L.3
Ranki, T.4
Kanerva, A.5
Pesonen, S.K.6
-
7
-
-
29344455240
-
Dual promoter-controlled oncolytic adenovirus CG5757 has strong tumor selectivity and significant antitumor efficacy in preclinical models
-
Li Y, Idamakanti N, Arroyo T, Thorne S, Reid T, Nichols S et al. Dual promoter-controlled oncolytic adenovirus CG5757 has strong tumor selectivity and significant antitumor efficacy in preclinical models. Clin Cancer Res 2005; 11: 8845-8855.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8845-8855
-
-
Li, Y.1
Idamakanti, N.2
Arroyo, T.3
Thorne, S.4
Reid, T.5
Nichols, S.6
-
8
-
-
23744473063
-
Combination of gemcitabine and Ad5/3-D 24, a tropism modified conditionally replicating adenovirus, for the treatment of ovarian cancer
-
Raki M, Kanerva A, Ristimaki A, Desmond RA, Chen DT, Ranki T et al. Combination of gemcitabine and Ad5/3-D 24, a tropism modified conditionally replicating adenovirus, for the treatment of ovarian cancer. Gene Ther 2005; 12: 1198-1205.
-
(2005)
Gene Ther
, vol.12
, pp. 1198-1205
-
-
Raki, M.1
Kanerva, A.2
Ristimaki, A.3
Desmond, R.A.4
Chen, D.T.5
Ranki, T.6
-
9
-
-
66849141991
-
Effective gene-viral therapy of leukemia by a new fiber chimeric oncolytic adenovirus expressing TRAIL: In vitro and in vivo evaluation
-
Jin J, Liu H, Yang C, Li G, Liu X, Qian Q et al. Effective gene-viral therapy of leukemia by a new fiber chimeric oncolytic adenovirus expressing TRAIL: in vitro and in vivo evaluation. Mol Cancer Ther 2009; 8: 1387-1396.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1387-1396
-
-
Jin, J.1
Liu, H.2
Yang, C.3
Li, G.4
Liu, X.5
Qian, Q.6
-
10
-
-
77957571590
-
Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF
-
Koski A, Kangasniemi L, Escutenaire S, Pesonen S, Cerullo V, Diaconu I et al. Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF. Mol Ther 2010; 18: 1874-1884.
-
(2010)
Mol Ther
, vol.18
, pp. 1874-1884
-
-
Koski, A.1
Kangasniemi, L.2
Escutenaire, S.3
Pesonen, S.4
Cerullo, V.5
Diaconu, I.6
-
11
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific and long lasting antitumor immunity
-
Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific and long lasting antitumor immunity. Proc Natl Acad Sci USA 1993; 90: 3539-3543.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
Golumbek, P.4
Levitsky, H.5
Brose, K.6
-
12
-
-
31544478298
-
CG0070, a conditionally replicating granulocyte macrophage colony-stimulating factor -armed oncolytic adenovirus for the treatment of bladder cancer
-
Ramesh N, Ge Y, Ennist DL, Zhu M, Mina M, Ganesh S et al. CG0070, a conditionally replicating granulocyte macrophage colony-stimulating factor -armed oncolytic adenovirus for the treatment of bladder cancer. Clin Cancer Res 2006; 12: 305-312.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 305-312
-
-
Ramesh, N.1
Ge, Y.2
Ennist, D.L.3
Zhu, M.4
Mina, M.5
Ganesh, S.6
-
13
-
-
0036645430
-
Identification of human uroplakin ii promoter and its use in the construction of CG8840, a urotheliumspecific adenovirus variant that eliminates established bladder tumors in combination with docetaxel
-
Zhang J, Ramesh N, Chen Y, Li Y, Dilley J, Working P et al. Identification of human uroplakin ii promoter and its use in the construction of CG8840, a urotheliumspecific adenovirus variant that eliminates established bladder tumors in combination with docetaxel. Cancer Res 2002; 62: 3743-3750.
-
(2002)
Cancer Res
, vol.62
, pp. 3743-3750
-
-
Zhang, J.1
Ramesh, N.2
Chen, Y.3
Li, Y.4
Dilley, J.5
Working, P.6
-
14
-
-
0035417931
-
A hepatocellular carcinomaspecific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin
-
Li Y, Yu DC, Chen Y, Amin P, Zhang H, Nguyen N et al. A hepatocellular carcinomaspecific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin. Cancer Res 2001; 61: 6428-6436.
-
(2001)
Cancer Res
, vol.61
, pp. 6428-6436
-
-
Li, Y.1
Yu, D.C.2
Chen, Y.3
Amin, P.4
Zhang, H.5
Nguyen, N.6
-
15
-
-
76349109690
-
Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL
-
Huang JH, Zhang SN, Choi KJ, Choi IK, Kim JH, Lee MG et al. Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL. Mol Ther 2010; 2: 264-274.
-
(2010)
Mol Ther
, vol.2
, pp. 264-274
-
-
Huang, J.H.1
Zhang, S.N.2
Choi, K.J.3
Choi, I.K.4
Kim, J.H.5
Lee, M.G.6
-
16
-
-
33750332951
-
Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1in an immunocompetent murine model
-
Lee YS, Kim JH, Choi KJ, Choi IK, Kim H, Cho S et al. Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1in an immunocompetent murine model. Clin Cancer Res 2006; 12: 5859-5868.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5859-5868
-
-
Lee, Y.S.1
Kim, J.H.2
Choi, K.J.3
Choi, I.K.4
Kim, H.5
Cho, S.6
-
17
-
-
33845336115
-
A phase i study of OncoVEXGM-CSF,a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor
-
Hu JC, Coffin RS, Davis CJ, Graham NJ, Groves N, Guest PJ et al. A phase I study of OncoVEXGM-CSF,a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res 2006; 12: 6737-6747.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6737-6747
-
-
Hu, J.C.1
Coffin, R.S.2
Davis, C.J.3
Graham, N.J.4
Groves, N.5
Guest, P.J.6
-
18
-
-
0034721737
-
Structure of murine CTLA-4 and its role in modulating T cell responsiveness
-
Ostrov DA, Shi W, Schwartz JC, Almo SC, Nathenson SG. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science 2000; 290: 816-819.
-
(2000)
Science
, vol.290
, pp. 816-819
-
-
Ostrov, D.A.1
Shi, W.2
Schwartz, J.C.3
Almo, S.C.4
Nathenson, S.G.5
-
20
-
-
15844380367
-
Regulation of CTLA-4 expression during T cell activation
-
Perkins D, Wang Z, Donovan C, He H, Mark D, Guan G et al. Regulation of CTLA-4 expression during T cell activation. J Immunol 1996; 156: 4154-4159.
-
(1996)
J Immunol
, vol.156
, pp. 4154-4159
-
-
Perkins, D.1
Wang, Z.2
Donovan, C.3
He, H.4
Mark, D.5
Guan, G.6
-
21
-
-
0036214017
-
The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
-
Carreno BM, Collins M. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu Rev Immunol 2002; 20: 29-53.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 29-53
-
-
Carreno, B.M.1
Collins, M.2
-
22
-
-
33747878218
-
2006Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma
-
Maker AV, Yang JC, Sherry RM, Topalian SL, Kammula US, Royal RE et al. 2006Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma. J Immunother 1997; 29: 455-463.
-
(1997)
J Immunother
, vol.29
, pp. 455-463
-
-
Maker, A.V.1
Yang, J.C.2
Sherry, R.M.3
Topalian, S.L.4
Kammula, U.S.5
Royal, R.E.6
-
23
-
-
0030853610
-
Enhanced induction of anti-tumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: The effect is manifested only at the restricted tumor-bearing stages
-
Yang YF, Zou JP, Mu J, Wijesuriya R, Ono S, Walunas T et al. Enhanced induction of anti-tumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages. Cancer Res 1997; 57: 4036-4041.
-
(1997)
Cancer Res
, vol.57
, pp. 4036-4041
-
-
Yang, Y.F.1
Zou, J.P.2
Mu, J.3
Wijesuriya, R.4
Ono, S.5
Walunas, T.6
-
24
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996; 271: 1734-1736.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
25
-
-
0030743846
-
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
-
Kwon ED, Hurwitz AA, Foster BA, Madias C, Feldhaus AL, Greenberg NM et al. Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer. Proc Natl Acad Sci USA 1997; 94: 8099-8103.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8099-8103
-
-
Kwon, E.D.1
Hurwitz, A.A.2
Foster, B.A.3
Madias, C.4
Feldhaus, A.L.5
Greenberg, N.M.6
-
26
-
-
33646886997
-
Biologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanoma
-
Reuben JM, Lee BN, Li C, Gomez-Navarro J, Bozon VA, Parker CA et al. Biologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanoma. Cancer 2006; 106: 2437-2444.
-
(2006)
Cancer
, vol.106
, pp. 2437-2444
-
-
Reuben, J.M.1
Lee, B.N.2
Li, C.3
Gomez-Navarro, J.4
Bozon, V.A.5
Parker, C.A.6
-
27
-
-
3242882924
-
Granulocyte- macrophage colony stimulating factor: An adjuvant for cancer vaccines
-
Chang DZ, Lomazow W, Joy Somberg C, Stan R, Perales MA. Granulocyte- macrophage colony stimulating factor: an adjuvant for cancer vaccines. Hematology 2004; 9: 207-215.
-
(2004)
Hematology
, vol.9
, pp. 207-215
-
-
Chang, D.Z.1
Lomazow, W.2
Joy Somberg, C.3
Stan, R.4
Perales, M.A.5
-
28
-
-
30344449182
-
Functions of granulocyte-macrophage colony-stimulating factor
-
Fleetwood AJ, Cook AD, Hamilton JA. Functions of granulocyte-macrophage colony-stimulating factor. Crit Rev Immunol 2005; 25: 405-428.
-
(2005)
Crit Rev Immunol
, vol.25
, pp. 405-428
-
-
Fleetwood, A.J.1
Cook, A.D.2
Hamilton, J.A.3
-
29
-
-
44249090471
-
Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity
-
Simmons AD, Moskalenko M, Creson J, Fang J, Yi S, VanRoey MJ et al. Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity. Cancer Immunol Immunother 2008; 57: 1263-1270.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1263-1270
-
-
Simmons, A.D.1
Moskalenko, M.2
Creson, J.3
Fang, J.4
Yi, S.5
Vanroey, M.J.6
-
30
-
-
33745851479
-
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
-
Quezada SA, Peggs KS, Curran MA, Allison JP. CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells. J Clin Invest 2006; 116: 1935-1945.
-
(2006)
J Clin Invest
, vol.116
, pp. 1935-1945
-
-
Quezada, S.A.1
Peggs, K.S.2
Curran, M.A.3
Allison, J.P.4
-
31
-
-
42949105127
-
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
-
Hodi FS, Butler M, Oble DA, Seiden MV, Haluska FG, Kruse A et al. Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients. Proc Natl Acad Sci USA 2008; 105: 3005-3010.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3005-3010
-
-
Hodi, F.S.1
Butler, M.2
Oble, D.A.3
Seiden, M.V.4
Haluska, F.G.5
Kruse, A.6
-
32
-
-
28844444483
-
Recent progress in the battle between oncolytic viruses and tumours
-
Parato KA, Senger D, Forsyth PA, Bell JC. Recent progress in the battle between oncolytic viruses and tumours. Nat Rev Cancer 2005; 5: 965-976.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 965-976
-
-
Parato, K.A.1
Senger, D.2
Forsyth, P.A.3
Bell, J.C.4
-
33
-
-
33846650370
-
Clinical trial results with oncolytic virotherapy: A century of promise, a decade of progress
-
Liu TC, Galanis E, Kirn D. Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress. Nat Clin Pract Oncol 2007; 4: 101-117.
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 101-117
-
-
Liu, T.C.1
Galanis, E.2
Kirn, D.3
-
34
-
-
0022445670
-
Rapid colorimetric assay for cell growth and survival modifications to the tetrazolium dye procedure giving improved sensitivity and eliability
-
Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival modifications to the tetrazolium dye procedure giving improved sensitivity and eliability. J Immunol Methods 1986; 89: 271-277.
-
(1986)
J Immunol Methods
, vol.89
, pp. 271-277
-
-
Denizot, F.1
Lang, R.2
-
35
-
-
33745158157
-
A simple method of estimating fifty percent endpoints
-
Reed L, Muench H. A simple method of estimating fifty percent endpoints. Am J Hyg 1938; 27: 493-497.
-
(1938)
Am J Hyg
, vol.27
, pp. 493-497
-
-
Reed, L.1
Muench, H.2
-
36
-
-
60549100362
-
Antitumoral immune response by recruitment and expansion of dendritic cells in tumors infected with telomerase-dependent oncolytic viruses
-
Edukulla R, Woller N, Mundt B, Knocke S, Gürlevik E, Saborowski M et al. Antitumoral immune response by recruitment and expansion of dendritic cells in tumors infected with telomerase-dependent oncolytic viruses. Cancer Res 2009; 69: 1448-1458.
-
(2009)
Cancer Res
, vol.69
, pp. 1448-1458
-
-
Edukulla, R.1
Woller, N.2
Mundt, B.3
Knocke, S.4
Gürlevik, E.5
Saborowski, M.6
-
37
-
-
84867399393
-
Targeted cancer immunotherapy with oncolytic adenovirus coding for a fully human monoclonal antibody specific for CTLA-4
-
Dias JD, Hemminki O, Diaconu I, Hirvinen M, Bonetti A, Guse K et al. Targeted cancer immunotherapy with oncolytic adenovirus coding for a fully human monoclonal antibody specific for CTLA-4. Gene Therapy 2011; 10: 1-11.
-
(2011)
Gene Therapy
, vol.10
, pp. 1-11
-
-
Dias, J.D.1
Hemminki, O.2
Diaconu, I.3
Hirvinen, M.4
Bonetti, A.5
Guse, K.6
-
38
-
-
0023878440
-
Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation
-
Kaushansky K, Lin N, Adamson JW. Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation. J Clin Invest 1988; 81: 92-97.
-
(1988)
J Clin Invest
, vol.81
, pp. 92-97
-
-
Kaushansky, K.1
Lin, N.2
Adamson, J.W.3
-
39
-
-
84869095632
-
A first in human phase 1 study of CG0070, a GM-CSF expressing oncolytic adenovirus, for the treatment of nonmuscle invasive bladder cancer
-
Burke JM, Lamm DL, Meng MV, Nemunaitis JJ, Stephenson JJ, Arseneau JC et al. A first in human phase 1 study of CG0070, a GM-CSF expressing oncolytic adenovirus, for the treatment of nonmuscle invasive bladder cancer. J Urol 2012; 188: 2391-2397.
-
(2012)
J Urol
, vol.188
, pp. 2391-2397
-
-
Burke, J.M.1
Lamm, D.L.2
Meng, M.V.3
Nemunaitis, J.J.4
Stephenson, J.J.5
Arseneau, J.C.6
-
40
-
-
58349090027
-
Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF
-
Fong L, Kwek SS, O'Brien S, Kavanagh B, McNeel DG, Weinberg V et al. potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF. Cancer Res 2009; 69: 609-615.
-
(2009)
Cancer Res
, vol.69
, pp. 609-615
-
-
Fong, L.1
Kwek, S.S.2
O'brien, S.3
Kavanagh, B.4
McNeel, D.G.5
Weinberg, V.6
|