-
1
-
-
43049176170
-
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
-
Akinc, A. et al. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat. Biotechnol. 26, 561-569 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 561-569
-
-
Akinc, A.1
-
2
-
-
76649098887
-
Lipid-like materials for low-dose, in vivo gene silencing
-
Love, K. T. et al. Lipid-like materials for low-dose, in vivo gene silencing. Proc. Natl. Acad. Sci. USA 107, 1864-1869 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 1864-1869
-
-
Love, K.T.1
-
3
-
-
84896519424
-
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
-
Dong, Y. et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. Proc. Natl. Acad. Sci. USA 111, 3955-3960 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 3955-3960
-
-
Dong, Y.1
-
4
-
-
84903643579
-
Degradable lipid nanoparticles with predictable in vivo sirna delivery activity
-
Whitehead, K. A. et al. Degradable lipid nanoparticles with predictable in vivo sirna delivery activity. Nat. commun. 5 (2014) doi: 10.1038/ncomms5277.
-
(2014)
Nat. Commun.
, vol.5
-
-
Whitehead, K.A.1
-
5
-
-
84949637138
-
An orthogonal array optimization of lipid-like nanoparticles for mRNA delivery in vivo
-
Li, B. et al. An orthogonal array optimization of lipid-like nanoparticles for mRNA delivery in vivo. Nano. Lett. 15, 8099-8107 (2015).
-
(2015)
Nano. Lett.
, vol.15
, pp. 8099-8107
-
-
Li, B.1
-
6
-
-
84946962398
-
Optimization of lipid nanoparticle formulations for mRNA delivery in vivo with fractional factorial and definitive screening designs
-
Kauffman, K. J. et al. Optimization of lipid nanoparticle formulations for mRNA delivery in vivo with fractional factorial and definitive screening designs. Nano. Lett. 15, 7300-7306 (2015).
-
(2015)
Nano. Lett.
, vol.15
, pp. 7300-7306
-
-
Kauffman, K.J.1
-
7
-
-
70349687233
-
Lipid-like nanoparticles for small interfering RNA delivery to endothelial cells
-
Wang, M. et al. Lipid-like nanoparticles for small interfering RNA delivery to endothelial cells. Adv. Funct. Mater. 19, 3112-3118 (2009).
-
(2009)
Adv. Funct. Mater.
, vol.19
, pp. 3112-3118
-
-
Wang, M.1
-
8
-
-
84908051604
-
Enhanced intracellular siRNA delivery using bioreducible lipid-like nanoparticles
-
Wang, M. et al. Enhanced intracellular siRNA delivery using bioreducible lipid-like nanoparticles. Adv. Healthc. Mater. 3, 1398-1403 (2014).
-
(2014)
Adv. Healthc. Mater.
, vol.3
, pp. 1398-1403
-
-
Wang, M.1
-
9
-
-
80155200721
-
Therapeutic siRNA silencing in inflammatory monocytes in mice
-
Leuschner, F. et al. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat. Biotechnol. 29, 1005-1010 (2011).
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 1005-1010
-
-
Leuschner, F.1
-
10
-
-
67349183756
-
Development of lipidoid-siRNA formulations for systemic delivery to the liver
-
Akinc, A. et al. Development of lipidoid-siRNA formulations for systemic delivery to the liver. Mol. Ther. 17, 872-879 (2009).
-
(2009)
Mol. Ther.
, vol.17
, pp. 872-879
-
-
Akinc, A.1
-
11
-
-
71949099757
-
Lipid-based nanotherapeutics for siRNA delivery
-
Schroeder, A., Levins, C. G., Cortez, C., Langer, R. & Anderson, D. G. Lipid-based nanotherapeutics for siRNA delivery. J. Intern. Med. 267, 9-21 (2010).
-
(2010)
J. Intern. Med.
, vol.267
, pp. 9-21
-
-
Schroeder, A.1
Levins, C.G.2
Cortez, C.3
Langer, R.4
Anderson, D.G.5
-
12
-
-
84924190196
-
Combinatorial library strategies for synthesis of cationic lipid-like nanoparticles and their potential medical applications
-
Altinoglu, S., Wang, M. & Xu, Q. Combinatorial library strategies for synthesis of cationic lipid-like nanoparticles and their potential medical applications. Nanomedicine 10, 643-657 (2015).
-
(2015)
Nanomedicine
, vol.10
, pp. 643-657
-
-
Altinoglu, S.1
Wang, M.2
Xu, Q.3
-
13
-
-
84881408604
-
Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery
-
Alabi, C. A. et al. Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery. Proc. Natl. Acad. Sci. USA 110, 12881-12886 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 12881-12886
-
-
Alabi, C.A.1
-
14
-
-
84947087821
-
Biomaterials for mRNA delivery
-
Islam, M. A. et al. Biomaterials for mRNA delivery. Biomater. Sci. 3, 1519-1533 (2015).
-
(2015)
Biomater. Sci.
, vol.3
, pp. 1519-1533
-
-
Islam, M.A.1
-
15
-
-
84908031186
-
Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo
-
Dong, Y. et al. Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo. Adv. Healthc. Mater. 3, 1392-1397 (2014).
-
(2014)
Adv. Healthc. Mater.
, vol.3
, pp. 1392-1397
-
-
Dong, Y.1
-
16
-
-
84939626439
-
Polymeric multifunctional nanomaterials for theranostics
-
Peng, H. et al. Polymeric multifunctional nanomaterials for theranostics. J. Mater. Chem. B 3, 6856-6870 (2015).
-
(2015)
J. Mater. Chem. B
, vol.3
, pp. 6856-6870
-
-
Peng, H.1
-
17
-
-
84947087822
-
A7RC peptide modified paclitaxel liposomes dually target breast cancer
-
Cao, J. et al. A7RC peptide modified paclitaxel liposomes dually target breast cancer. Biomater. Sci. 3, 1545-1554 (2015).
-
(2015)
Biomater. Sci.
, vol.3
, pp. 1545-1554
-
-
Cao, J.1
-
18
-
-
84940954525
-
Non-genetic engineering of cells for drug delivery and cell-based therapy
-
Wang, Q. et al. Non-genetic engineering of cells for drug delivery and cell-based therapy. Adv. Drug Deliv. Rev. 91, 125-140 (2015).
-
(2015)
Adv. Drug Deliv. Rev.
, vol.91
, pp. 125-140
-
-
Wang, Q.1
-
19
-
-
84923973108
-
Nanocarriers in therapy of infectious and inflammatory diseases
-
Ikoba, U. et al. Nanocarriers in therapy of infectious and inflammatory diseases. Nanoscale 7, 4291-4305 (2015).
-
(2015)
Nanoscale
, vol.7
, pp. 4291-4305
-
-
Ikoba, U.1
-
20
-
-
84923940272
-
An intestinal trojan horse for gene delivery
-
Peng, H., Wang, C., Xu, X., Yu, C. & Wang, Q. An intestinal trojan horse for gene delivery. Nanoscale 7, 4354-4360 (2015).
-
(2015)
Nanoscale
, vol.7
, pp. 4354-4360
-
-
Peng, H.1
Wang, C.2
Xu, X.3
Yu, C.4
Wang, Q.5
-
21
-
-
84897500069
-
The role of glucose transporters in the distribution of p-aminophenyl-α -D-mannopyranoside modified liposomes within mice brain
-
Du, D. et al. The role of glucose transporters in the distribution of p-aminophenyl-α -D-mannopyranoside modified liposomes within mice brain. J Control. Release 182, 99-110 (2015).
-
(2015)
J Control. Release
, vol.182
, pp. 99-110
-
-
Du, D.1
-
22
-
-
84894985306
-
The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy
-
Liu, M. et al. The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy. Biomaterials 35, 3697-3707 (2014).
-
(2014)
Biomaterials
, vol.35
, pp. 3697-3707
-
-
Liu, M.1
-
23
-
-
84894812831
-
Tamoxifen embedded in lipid bilayer improved the oncotarget of liposomal daunorubicin in vivo
-
Li, M. H. et al. Tamoxifen embedded in lipid bilayer improved the oncotarget of liposomal daunorubicin in vivo. J. Mater. Chem. B 2, 1619-1625 (2014).
-
(2014)
J. Mater. Chem. B
, vol.2
, pp. 1619-1625
-
-
Li, M.H.1
-
24
-
-
84878279815
-
Nanostraw-electroporation system for highly efficient intracellular delivery and transfection
-
Xie, X. et al. Nanostraw-electroporation system for highly efficient intracellular delivery and transfection. ACS nano 7, 4351-4351 (2013).
-
(2013)
ACS Nano
, vol.7
, pp. 4351
-
-
Xie, X.1
-
25
-
-
84860539841
-
Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin
-
Kariko, K., Muramatsu, H., Keller, J. M. & Weissman, D. Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin. Mol. Ther. 20, 948-953 (2012).
-
(2012)
Mol. Ther.
, vol.20
, pp. 948-953
-
-
Kariko, K.1
Muramatsu, H.2
Keller, J.M.3
Weissman, D.4
-
26
-
-
84903649476
-
Messenger RNA (mRNA) nanoparticle tumour vaccination
-
Phua, K. K., Nair, S. K. & Leong, K. W. Messenger rna (mrna) nanoparticle tumour vaccination. Nanoscale 6, 7715-7729 (2014).
-
(2014)
Nanoscale
, vol.6
, pp. 7715-7729
-
-
Phua, K.K.1
Nair, S.K.2
Leong, K.W.3
-
27
-
-
84921794613
-
mRNA-based therapeutics-developing a new class of drugs
-
Sahin, U., Kariko, K. & Tu reci, O. mRNA-based therapeutics-developing a new class of drugs. Nat. Rev. Drug Discov. 13, 759-780 (2014).
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 759-780
-
-
Sahin, U.1
Kariko, K.2
Tureci, O.3
-
28
-
-
79958296153
-
In vitro and in vivo mRNA delivery using lipid-enveloped ph-responsive polymer nanoparticles
-
Su, X., Fricke, J., Kavanagh, D. G. & Irvine, D. J. In vitro and in vivo mRNA delivery using lipid-enveloped ph-responsive polymer nanoparticles. Mol. Pharm. 8, 774-787 (2011).
-
(2011)
Mol. Pharm.
, vol.8
, pp. 774-787
-
-
Su, X.1
Fricke, J.2
Kavanagh, D.G.3
Irvine, D.J.4
-
29
-
-
79955054845
-
mRNA as gene therapeutic: How to control protein expression
-
Tavernier, G. et al. mRNA as gene therapeutic: how to control protein expression. J. Control. Release 150, 238-247 (2011).
-
(2011)
J. Control. Release
, vol.150
, pp. 238-247
-
-
Tavernier, G.1
-
30
-
-
84885676364
-
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
-
Zangi, L. et al. Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat. Biotechnol. 31, 898-907 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 898-907
-
-
Zangi, L.1
-
31
-
-
77956313412
-
4 by a cyanuric acid based host via contact ion-pair interactions
-
4 by a cyanuric acid based host via contact ion-pair interactions. Chem. Commun. 46, 6741-6743 (2010).
-
(2010)
Chem. Commun.
, vol.46
, pp. 6741-6743
-
-
Ravikumar, I.1
Ghosh, P.2
-
32
-
-
2942632966
-
Pegylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles
-
Mishra, S., Webster, P. & Davis, M. E. Pegylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles. Eur. J. Cell Biol. 83, 97-111 (2004).
-
(2004)
Eur. J. Cell Biol.
, vol.83
, pp. 97-111
-
-
Mishra, S.1
Webster, P.2
Davis, M.E.3
-
33
-
-
84870250531
-
Pegylated nanoparticles for biological and pharmaceutical applications
-
Otsuka, H., Nagasaki, Y. & Kataoka, K. Pegylated nanoparticles for biological and pharmaceutical applications. Eur. J Cel. Biol. 64, 246-255 (2012).
-
(2012)
Eur. J Cel. Biol.
, vol.64
, pp. 246-255
-
-
Otsuka, H.1
Nagasaki, Y.2
Kataoka, K.3
-
34
-
-
84873477636
-
Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format
-
Phua, K. K., Leong, K. W. & Nair, S. K. Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format. J Control. Release 166, 227-233 (2013).
-
(2013)
J Control. Release
, vol.166
, pp. 227-233
-
-
Phua, K.K.1
Leong, K.W.2
Nair, S.K.3
|